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Full-Text Articles in Social and Behavioral Sciences
The Effect Of Sinoaortic Denervation On Renal Wrap Hypertension, J. Mark Van Ness, Carmen Hinojosa-Laborde, Teresa Craig, Joseph R. Haywood
The Effect Of Sinoaortic Denervation On Renal Wrap Hypertension, J. Mark Van Ness, Carmen Hinojosa-Laborde, Teresa Craig, Joseph R. Haywood
College of the Pacific Faculty Articles
The purpose of this study was to determine whether sinoaortic deafferentation (SAD) alters the severity of hypertension or sympathoadrenal contribution to mean blood pressure (MAP) during renal wrap hypertension. Male Sprague-Dawley rats were implanted with radiotelemetry transmitters for 24-hour recording of MAP and heart rate. All rats underwent either SAD or sham SAD (Intact) surgery and were allowed to recover for 10 to 14 days. The rats were then assigned to a normotensive (Sham) group or a hypertensive (Wrap) group in which 1-kidney figure-8 renal wrap was performed. SAD increased the acute MAP response to renal wrap (Intact-Sham=5+/-1 mm Hg, …
The Effect Of Sinoaortic Deafferentation On Renal Wrap Hypertension, J. Mark Van Ness, Teresa Craig, Carmen Hinojosa-Laborde, Joseph R. Haywood
The Effect Of Sinoaortic Deafferentation On Renal Wrap Hypertension, J. Mark Van Ness, Teresa Craig, Carmen Hinojosa-Laborde, Joseph R. Haywood
College of the Pacific Faculty Articles
The purpose of this study was to determine whether sinoaortic deafferentation (SAD) alters the severity of hypertension or sympathoadrenal contribution to mean blood pressure (MAP) during renal wrap hypertension. Male Sprague-Dawley rats were implanted with radiotelemetry transmitters for 24-hour recording of MAP and heart rate. All rats underwent either SAD or sham SAD (Intact) surgery and were allowed to recover for 10 to 14 days. The rats were then assigned to a normotensive (Sham) group or a hypertensive (Wrap) group in which 1-kidney figure-8 renal wrap was performed. SAD increased the acute MAP response to renal wrap (Intact-Sham=5+/-1 mm Hg, …