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Survival Analysis Commons

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Articles 1 - 4 of 4

Full-Text Articles in Survival Analysis

Deletion/Substitution/Addition Algorithm For Partitioning The Covariate Space In Prediction, Annette Molinaro, Mark J. Van Der Laan Nov 2004

Deletion/Substitution/Addition Algorithm For Partitioning The Covariate Space In Prediction, Annette Molinaro, Mark J. Van Der Laan

U.C. Berkeley Division of Biostatistics Working Paper Series

We propose a new method for predicting censored (and non-censored) clinical outcomes from a highly-complex covariate space. Previously we suggested a unified strategy for predictor construction, selection, and performance assessment. Here we introduce a new algorithm which generates a piecewise constant estimation sieve of candidate predictors based on an intensive and comprehensive search over the entire covariate space. This algorithm allows us to elucidate interactions and correlation patterns in addition to main effects.


Estimating A Survival Distribution With Current Status Data And High-Dimensional Covariates, Mark J. Van Der Laan, Aad Van Der Vaart Sep 2004

Estimating A Survival Distribution With Current Status Data And High-Dimensional Covariates, Mark J. Van Der Laan, Aad Van Der Vaart

U.C. Berkeley Division of Biostatistics Working Paper Series

We consider the inverse problem of estimating a survival distribution when the survival times are only observed to be in one of the intervals of a random bisection of the time axis. We are particularly interested in the case that high-dimensional and/or time-dependent covariates are available, and/or the survival events and censoring times are only conditionally independent given the covariate process. The method of estimation consists of regularizing the survival distribution by taking the primitive function or smoothing, estimating the regularized parameter by using estimating equations, and finally recovering an estimator for the parameter of interest.


Nonparametric And Semiparametric Inference For Models Of Tumor Size And Metastasis, Debashis Ghosh May 2004

Nonparametric And Semiparametric Inference For Models Of Tumor Size And Metastasis, Debashis Ghosh

The University of Michigan Department of Biostatistics Working Paper Series

There has been some recent work in the statistical literature for modelling the relationship between the size of primary cancers and the occurrences of metastases. While nonparametric methods have been proposed for estimation of the tumor size distribution at which metastatic transition occurs, their asymptotic properties have not been studied. In addition, no testing or regression methods are available so that potential confounders and prognostic factors can be adjusted for. We develop a unified approach to nonparametric and semiparametric analysis of modelling tumor size-metastasis data in this article. An equivalence between the models considered by previous authors with survival data …


Estimating Predictors For Long- Or Short-Term Survivors, Lu Tian, Wei Wang, L. J. Wei Nov 2003

Estimating Predictors For Long- Or Short-Term Survivors, Lu Tian, Wei Wang, L. J. Wei

Harvard University Biostatistics Working Paper Series

No abstract provided.