Open Access. Powered by Scholars. Published by Universities.®
- Discipline
- Keyword
-
- Cardiovascular diseases; Cox's model; nonparametric functional estimation; risk index; ROC analysis; survival analysis (1)
- Interval-censored data; treatment comparison; weighted log-rank test; permutation test (1)
- Multiplie imputation; mother-to-child transmission of HIV; mixture (1)
- Nonparametric; semi-parametric; variable importanct (1)
- Threshold; partial likelihood; survival; ROC curve; concordance; maximal chi-square (1)
Articles 1 - 8 of 8
Full-Text Articles in Survival Analysis
Optimal Cutpoint Estimation With Censored Data, Mithat Gonen, Camelia Sima
Optimal Cutpoint Estimation With Censored Data, Mithat Gonen, Camelia Sima
Memorial Sloan-Kettering Cancer Center, Dept. of Epidemiology & Biostatistics Working Paper Series
We consider the problem of selecting an optimal cutpoint for a continuous marker when the outcome of interest is subject to right censoring. Maximal chi square methods and receiver operating characteristic (ROC) curves-based methods are commonly-used when the outcome is binary. In this article we show that selecting the cutpoint that maximizes the concordance, a metric similar to the area under an ROC curve, is equivalent to maximizing the Youden index, a popular criterion when the ROC curve is used to choose a threshold. We use this as a basis for proposing maximal concordance as a metric to use with …
A New Class Of Rank Tests For Interval-Censored Data, Guadalupe Gomez, Ramon Oller Pique
A New Class Of Rank Tests For Interval-Censored Data, Guadalupe Gomez, Ramon Oller Pique
Harvard University Biostatistics Working Paper Series
No abstract provided.
Calibrating Parametric Subject-Specific Risk Estimation, Tianxi Cai, Lu Tian, Hajime Uno, Scott D. Solomon, L. J. Wei
Calibrating Parametric Subject-Specific Risk Estimation, Tianxi Cai, Lu Tian, Hajime Uno, Scott D. Solomon, L. J. Wei
Harvard University Biostatistics Working Paper Series
No abstract provided.
Estimation For Arbitrary Functionals Of Survival, Kyle Rudser, Michael L. Leblanc, Scott S. Emerson
Estimation For Arbitrary Functionals Of Survival, Kyle Rudser, Michael L. Leblanc, Scott S. Emerson
UW Biostatistics Working Paper Series
No abstract provided.
Joint Spatial Modeling Of Recurrent Infection And Growth With Processes Under Intermittent Observation, Farouk S. Nathoo
Joint Spatial Modeling Of Recurrent Infection And Growth With Processes Under Intermittent Observation, Farouk S. Nathoo
COBRA Preprint Series
In this article we present new statistical methodology for longitudinal studies in forestry where trees are subject to recurrent infection and the hazard of infection depends on tree growth over time. Understanding the nature of this dependence has important implications for reforestation and breeding programs. Challenges arise for statistical analysis in this setting with sampling schemes leading to panel data, exhibiting dynamic spatial variability, and incomplete covariate histories for hazard regression. In addition, data are collected at a large number of locations which poses computational difficulties for spatiotemporal modeling. A joint model for infection and growth is developed; wherein, a …
Nonparametric Regression Using Local Kernel Estimating Equations For Correlated Failure Time Data, Zhangsheng Yu, Xihong Lin
Nonparametric Regression Using Local Kernel Estimating Equations For Correlated Failure Time Data, Zhangsheng Yu, Xihong Lin
Harvard University Biostatistics Working Paper Series
No abstract provided.
Semiparametric Maximum Likelihood Estimation In Normal Transformation Models For Bivariate Survival Data, Yi Li, Ross L. Prentice, Xihong Lin
Semiparametric Maximum Likelihood Estimation In Normal Transformation Models For Bivariate Survival Data, Yi Li, Ross L. Prentice, Xihong Lin
Harvard University Biostatistics Working Paper Series
No abstract provided.
Multiple Imputation Of Timing Of Mother-To-Child Transmission Of Hiv, Elizabeth Brown, Ying Qing Chen
Multiple Imputation Of Timing Of Mother-To-Child Transmission Of Hiv, Elizabeth Brown, Ying Qing Chen
UW Biostatistics Working Paper Series
In this paper, we present a model for imputing timing of mother-to- child transmission (MTCT) of HIV. The method re ects the three modes of MTCT of HIV: in utero, during delivery and via breastfeeding and can accomodate shapes for the baseline hazard that vary between infants. Ad- ditionally, it allows that the majority of infants do not experience MTCT of HIV. Final analyses from the imputed data sets are combined in a mul- tiple imputation framework. The methods is illustrated on a large trial designed to assess the use of antibiotics in preventing MTCT of HIV and is validated …