Design of Experiments and Sample Surveys Commons^™

Action Plan: Gym Cleanliness At The Jaeger Center, Blair A. O'Connor

CAFE Symposium 2024

I have created an action plan to assess current patrons' satisfaction with the cleaning materials provided at the Gettysburg College Jaeger Center, and increase the amount or variety if the need is there. Due to a combination of behaviors and bacteria in the Jaeger Center, gym users are at risk of contracting infections. The objective of this plan is for gym users to feel more empowered and safe in their environment. While there may be individuals who feel like increased disinfecting efforts and supplies are not necessary at the Jaeger Center, what may not be a concern for one person …

A Comparison Of Quaternion Neural Network Backpropagation Algorithms, Jeremiah Bill, Bruce A. Cox, Lance Champaign

Faculty Publications

This research paper focuses on quaternion neural networks (QNNs) - a type of neural network wherein the weights, biases, and input values are all represented as quaternion numbers. Previous studies have shown that QNNs outperform real-valued neural networks in basic tasks and have potential in high-dimensional problem spaces. However, research on QNNs has been fragmented, with contributions from different mathematical and engineering domains leading to unintentional overlap in QNN literature. This work aims to unify existing research by evaluating four distinct QNN backpropagation algorithms, including the novel GHR-calculus backpropagation algorithm, and providing concise, scalable implementations of each algorithm using a …

Uconn Baseball Batting Order Optimization, Gavin Rublewski, Gavin Rublewski

Honors Scholar Theses

Challenging conventional wisdom is at the very core of baseball analytics. Using data and statistical analysis, the sets of rules by which coaches make decisions can be justified, or possibly refuted. One of those sets of rules relates to the construction of a batting order. Through data collection, data adjustment, the construction of a baseball simulator, and the use of a Monte Carlo Simulation, I have assessed thousands of possible batting orders to determine the roster-specific strategies that lead to optimal run production for the 2023 UConn baseball team. This paper details a repeatable process in which basic player statistics …

Arousing Motives Or Eliciting Stories? On The Role Of Pictures In A Picture–Story Exercise, Philipp Schäpers, Stefan Krumm, Filip Lievens, Nikola Stenzel

Research Collection Lee Kong Chian School Of Business

Picture–story exercises (PSE) form a popular measurement approach that has been widely used for the assessment of implicit motives. However, current theorizing offers two diverging perspectives on the role of pictures in PSEs: either to elicit stories or to arouse motives. In the current study, we tested these perspectives in an experimental design. We administered a PSE either with or without pictures. Results from N = 281 participants revealed that the experimental manipulation had a medium to large effect for the affiliation and power motive domains, but no effect for the achievement motive domain. We conclude that the herein chosen …

Modeling And Fitting Two-Way Tables Containing Outliers, David L. Farnsworth

Articles

A model is proposed for two-way tables of measurement data containing outliers. The two independent variables are categorical and error free. Neither missing values nor replication are present. The model consists of the sum of a customary additive part that can be fit using least squares and a part that is composed of outliers. Recommendations are made for methods for identifying cells containing outliers and for fitting the model. A graph of the observations is used to determine the outliers’ locations. For all cells containing an outlier, replacement values are determined simultaneously using a classical missing-data tool. The result is …

Reducing Print Time While Minimizing Loss In Mechanical Properties In Consumer Fdm Parts, Long Le, Mitchel A. Rabsatt, Hamid Eisazadeh, Mona Torabizadeh

Mechanical & Aerospace Engineering Faculty Publications

Fused deposition modeling (FDM), one of various additive manufacturing (AM) technologies, offers a useful and accessible tool for prototyping and manufacturing small volume functional parts. Polylactic acid (PLA) is among the commonly used materials for this process. This study explores the mechanical properties and print time of additively manufactured PLA with consideration to various process parameters. The objective of this study is to optimize the process parameters for the fastest print time possible while minimizing the loss in ultimate strength. Design of experiments (DOE) was employed using a split-plot design with five factors. Analysis of variance (ANOVA) was employed to …

Investigation And Statistical Modeling Of The Mechanical Properties Of Additively Manufactured Lattices, Derek G. Spear, Anthony N. Palazotto

Faculty Publications

This paper describes the background, test methodology, and experimental results associated with the testing and analysis of quasi-static compression testing of additively manufactured open-cell lattice structures. The study aims to examine the effect of lattice topology, cell size, cell density, and surface thickness on the mechanical properties of lattice structures. Three lattice designs were chosen, the Diamond, I-WP, and Primitive Triply Periodic Minimal Surfaces (TPMSs). Uniaxial compression tests were conducted for every combination of the three lattice designs, three cell sizes, three cell densities, and three surface thicknesses. In order to perform an efficient experiment and gain the most information …

Tennis Anyone? Teaching Experimental Design By Designing And Executing A Tennis Ball Experiment, Laura Pyott

Mathematics Faculty Publications

Understanding the abstract principles of statistical experimental design can challenge undergraduate students, especially when learned in a lecture setting. This article presents a concrete and easily replicated example of experimental design principles in action through a hands-on learning activity for students enrolled in an experimental design course. The activity, conducted during five 50-min classes, requires the students to work as a team to design and execute a simple and safe factorial experiment and collect and analyze the data. During three in-class design meetings, the students design and plan all aspects of the experiment, including choosing the response variable and factors, …

Resource-Saving Technologies For The Production Of Elastic Leather Materials: Collective Monograph, Olena Korotych, Anatolii Danylkovych, Serhii Bilinskyi, Serhii Bondarenko, Slava Branovitska, Vasyl Chervinskyi, Nataliia Khliebnikova, Alona Kudzieva, Viktor Lishchuk, Nataliia Lysenko, Olena Mokrousova, Nataliia Omelchenko, Vera Palamar, Yuliia Potakh, Oksana Romanyuk, Olga Sanginova, Oleksandr Zhyhotsky

Chemistry Publications and Other Works

This monograph contains a collection of recent research papers focusing on advancing existing technologies and developing new technologies to improve the environmentally friendliness and save resources during the production of elastic leather materials. The papers are organized based on the type of technological process used to preserve raw hides. A lot of attention is devoted to mathematical planning, simulations, and multicriteria optimization of the technological processes using newly developed chemical reagents. The monograph contains a complex study of physicochemical properties and characteristics of the resulting leather materials. The developed technologies were tested by the private joint-stock company Chinbar (Kyiv, Ukraine) …

Protocol For A National Probability Survey Using Home Specimen Collection Methods To Assess Prevalence And Incidence Of Sars-Cov-2 Infection And Antibody Response, Aaron J. Siegler, Patrick S. Sullivan, Travis Sanchez, Ben Lopman, Mansour Fahimi, Charles Sailey, Martin Frankel, Richard Rothenberg, Colleen F. Kelley, Heather Bradley

Publications and Research

Purpose: The U.S. response to the SARS-CoV-2 epidemic has been hampered by early and ongoing delays in testing for infection; without data on where infections were occurring and the magnitude of the epidemic, early public health responses were not data-driven. Understanding the prevalence of SARSCoV- 2 infections and immune response is critical to developing and implementing effective public health responses. Most serological surveys have been limited to localities that opted to conduct them and/or were based on convenience samples. Moreover, results of antibody testing might be subject to high false positive rates in the setting of low prevalence of immune …

Rdc Data Alternatives: Conducting Research During Covid-19, Kristi Thompson, Elizabeth Hill

Western Libraries Presentations

Recent physical distancing protocols pertaining to the COVID-19 Pandemic have meant that RDC researchers need to find alternatives ways of carrying out their research. The Real Time Remote Access (RTRA) program offers one alternative way to access confidential Statistics Canada data. Other options include using the Statistics Canada public use files and analyzing data from other sources.

The presenters, data librarians from Western Libraries will discuss the differences between the data that can be accessed through the RTRA the RDC. RTRA data is a very useful option for some types of questions but also has some important limitations. We will …

How We Can Extend The Standard Deviation Notion With Neutrosophic Interval And Quadruple Neutrosophic Numbers, Victor Christianto, Florentin Smarandache, Muhammad Aslam

Branch Mathematics and Statistics Faculty and Staff Publications

During scientific demonstrating of genuine specialized framework we can meet any sort and rate model vulnerability. Its reasons can be incognizance of modelers or information mistake. In this way, characterization of vulnerabilities, as for their sources, recognizes aleatory and epistemic ones. The aleatory vulnerability is an inalienable information variety related with the researched framework or its condition. Epistemic one is a vulnerability that is because of an absence of information on amounts or procedures of the framework or the earth [7]. Right now, we examine fourfold neutrosophic numbers and their potential application for practical displaying of physical frameworks, particularly in …

A Comparison Of Academic Performance Measures Of Hsta Participants With Non-Hsta Participants: Is It Possible To Narrow The African American-White Achievement Gap?, Sherron Mckendall, Alan Mckendall, Ann Chester

Faculty & Staff Scholarship

Historically, African American and other underserved students encounter academic challenges in pursuit of a college degree—one of which is their performance on standardized tests. This paper analyzes College Grade Point Averages (CGPAs), ACT Composite (ACTC), and SAT Total (SATT) scores of students who participated in the Health Sciences and Technology Academy (HSTA), an out-of-school-time (OST) program, and Non-HSTA (NHSTA) students attending West Virginia University. Traditionally, OST programs provide academic enrichment to underserved youth to increase their chances for post-secondary entry and success. Two-Way Factorial ANOVA determined if HSTA participants performed better on academic measures than their NHSTA counterparts. The ANOVAs …

Trends And Disparities In Self-Reported And Measured Osteoporosis Among Us Adults, 2007-2014., Qing Wu, Yingke Xu, Ge Lin

Environmental & Occupational Health Faculty Publications

(1) Background: Studies examining osteoporosis trends among US adults by different socioeconomic status (SES) are limited. The prevalence of self-reported osteoporosis in the US is rarely reported. (2) Methods: Data from the National Health and Nutritional Examination Survey (NHANES) between 2007–2008 and 2013–2014 cycles were analyzed. Age-adjusted prevalence of self-reported and that of measured osteoporosis were calculated overall and by sex, race/ethnicity, education attainment, and SES. (3) Results: The prevalence of self-reported osteoporosis was higher than that of measured osteoporosis in all three survey cycles for women, and in 2007–2008 and 2009–2010 for men. Participants with high school/GED or higher …

I Spy With My Little Eye … A Knee About To Go 'Pop'? Can Coaches And Sports Medicine Professionals Predict Who Is At Greater Risk Of Acl Rupture?, Anne Inger Mørtvedt, Tron Krosshaug, Roald Bahr, Erich Petushek

Michigan Tech Publications

BACKGROUND: The vertical drop jump (VDJ) test is widely used for clinical assessment of ACL injury risk, but it is not clear whether such assessments are valid.

AIM: To examine if sports medicine professionals and coaches are able to identify players at risk of sustaining an ACL injury by visually assessing player performance during a VDJ test.

METHODS: 102 video clips of elite female handball and football players performing a baseline VDJ test were randomly extracted from a 738-person prospective cohort study that tracked ACL injuries. Of the sample, 20 of 102 went on to suffer an ACL injury. These …

Animal Research, Accountability, Openness And Public Engagement: Report From An International Expert Forum, Elisabeth H. Ormandy, Daniel M. Weary, Katarina Cvek, Mark Fisher, Kathrin Herrmann, Pru Hobson-West, Michael Mcdonald, William Milsom, Margaret Rose, Andrew Rowan, Joanne Zurlo, Marina A.G. Von Keyserlingk

Oversight of Animal Experimentation Collection

In November 2013, a group of international experts in animal research policy (n = 11) gathered in Vancouver, Canada, to discuss openness and accountability in animal research. The primary objective was to bring together participants from various jurisdictions (United States, Sweden, Australia, New Zealand, Germany, Canada and the United Kingdom) to share practices regarding the governance of animals used in research, testing and education, with emphasis on the governance process followed, the methods of community engagement, and the balance of openness versus confidentiality. During the forum, participants came to a broad consensus on the need for: (a) evidence-based metrics to …

Optimal Design For A Causal Structure, Zaher Kmail

Department of Statistics: Dissertations, Theses, and Student Work

Linear models and mixed models are important statistical tools. But in many natural phenomena, there is more than one endogenous variable involved and these variables are related in a sophisticated way. Structural Equation Modeling (SEM) is often used to model the complex relationships between the endogenous and exogenous variables. It was first implemented in research to estimate the strength and direction of direct and indirect effects among variables and to measure the relative magnitude of each causal factor.

Historically, traditional optimal design theory focuses on univariate linear, nonlinear, and mixed models. There is no current literature on the subject of …

Maquiladoras In Central America: An Analysis Of Workforce Schedule, Productivity And Fatigue., Jose L. Barahona

Masters Theses & Specialist Projects

Textile factories or Maquiladoras are very abundant and predominant in Central American economies. However, they all do not have the same standardized work schedule or routines. Most of the Maquiladoras only follow schedules and regulations established by the current labor laws without taking into consideration many variables within their organization that could affect their overall performance. As a result, the purpose of the study is to analyze the current working structure of a textile Maquiladora and determine the most suitable schedule that will abide with the current working structure but also increase production levels, employee morale and decrease employee fatigue. …

Automated Monitoring Of Behaviour In Zebrafish After Invasive Procedures, Anthony G. Deakin, Jonathan Buckley, Hamzah S. Alzu'bi, Andrew R. Cossins, Joseph W. Spencer, Waleed Al'nuaimy, Iain S. Young, Jack S. Thomson, Lynne U. Sneddon

Validation of Animal Experimentation Collection

Fish are used in a variety of experimental contexts often in high numbers. To maintain their welfare and ensure valid results during invasive procedures it is vital that we can detect subtle changes in behaviour that may allow us to intervene to provide pain-relief. Therefore, an automated method, the Fish Behaviour Index (FBI), was devised and used for testing the impact of laboratory procedures and efficacy of analgesic drugs in the model species, the zebrafish. Cameras with tracking software were used to visually track and quantify female zebrafish behaviour in real time after a number of laboratory procedures including fin …

Is Animal-Based Biomedical Research Being Used In Its Original Context?, Constança Carvalho, Daniel Alves, Andrew Knight, Luís Vicente

Validation of Animal Experimentation Collection

No abstract provided.

Critically Evaluating Animal Research, Andrew Knight

Validation of Animal Experimentation Collection

No abstract provided.

A Simulation Study Of Diagnostics For Bias In Non-Probability Samples, Philip S. Boonstra, Roderick Ja Little, Brady T. West, Rebecca R. Andridge, Fernanda Alvarado-Leiton

The University of Michigan Department of Biostatistics Working Paper Series

A non-probability sampling mechanism is likely to bias estimates of parameters with respect to a target population of interest. This bias poses a unique challenge when selection is 'non-ignorable', i.e. dependent upon the unobserved outcome of interest, since it is then undetectable and thus cannot be ameliorated. We extend a simulation study by Nishimura et al. [International Statistical Review, 84, 43--62 (2016)], adding a recently published statistic, the so-called 'standardized measure of unadjusted bias', which explicitly quantifies the extent of bias under the assumption that a specified amount of non-ignorable selection exists. Our findings suggest that this new …

Recent Efforts To Elucidate The Scientific Validity Of Animal-Based Drug Tests By The Pharmaceutical Industry, Pro-Testing Lobby Groups, And Animal Welfare Organisations, Jarrod Bailey

Validation of Animal Experimentation Collection

Background: Even after several decades of human drug development, there remains an absence of published, substantial, comprehensive data to validate the use of animals in preclinical drug testing, and to point to their predictive nature with regard to human safety/toxicity and efficacy. Two recent papers, authored by pharmaceutical industry scientists, added to the few substantive publications that exist. In this brief article, we discuss both these papers, as well as our own series of three papers on the subject, and also various views and criticisms of lobby groups that advocate the animal testing of new drugs.

Main text: We argue …

Extrapolation Of Animal Research Data To Humans: An Analysis Of The Evidence, Rebecca Ram

Validation of Animal Experimentation Collection

The ethical arguments against animal experimentation remain ever-strong. In addition, the scientific case against the use of animals in research grows more compelling, with exponential progress in the development of alternative methods and new research technologies. The Dutch authorities recently announced an ambitious, but welcome, proposal to phase out “the use of laboratory animals in regulatory safety testing of chemicals, food ingredients, pesticides and (veterinary) medicines” by 2025, as well as “the use of laboratory animals for the release of biological products, such as vaccines” (Netherlands National Committee for the protection of animals used for scientific purposes, NCad, 2016, p. …

Recent Developments In Alternatives To Animal Testing, Katy Taylor

Application of Alternative Methods Collection

Methods that replace techniques that use live animals, or methods of testing substances without live animal use, are known as alternatives, replacements or non-animal methods. Some prefer the term advanced technologies given the fact that they often rely on more sophisticated technology and are more human- relevant than the animal test they replace (see Langley et al., 2015). There have been efforts to replace animal tests since the 1960s. Significant progress initially came in replacing animals used to diagnose human disease; to produce biological drugs (such as vaccines); and to safety test batches of these drugs as they were produced. …

The Changing Paradigm In Preclinical Toxicology: In Vitro And In Silico Methods In Liver Toxicity Evaluations, Fozia Noor

Application of Alternative Methods Collection

In vitro methods, based on human primary cells, cell lines, and genetically modified reporter cell lines, have greatly expanded the scope of in vitro toxicology. Other significant progress in the area of human-induced pluripotent stem cells (hiPSCs) (Asgari et al., 2010; Schwartz et al., 2014; Shinde et al., 2016; Shtrichman, Germanguz and Itskovitz-Eldor, 2013) is allowing the application of patient and disease-specific hiPSCs (Ghodsizadeh et al., 2010; McCracken et al., 2014; Siller et al., 2013). Moreover, the tools of precise genome editing with engineered nucleases, such as the zinc finger nucleases (zfns), the transcription activator-like effecter nucleases (talens) and, more …

How To Evaluate The Science Of Non-Human Animal Use In Biomedical Research And Testing: A Proposed Format For Debate, Ray Greek, Lisa A. Kramer

Validation of Alternative Methods Collection

Over time, the interpretation of science has occasionally been corrupted by vested interest groups, be they financially motivated or ego driven. Scientific consensus and widespread public beliefs usually catch up with the evidence, but this can take a very long time and often costs lives. The use of non-human animals in biomedical research and testing is a scientific endeavor and, as such, can and should be evaluated in light of the best science currently available. But facts that have been accepted in all areas of science are routinely ignored or called into question by well-funded, vested interest groups, compromising the …

How Can The Final Goal Of Completely Replacing Animal Procedures Successfully Be Achieved?, Christiane Baumgartl-Simons, Christiane Hohense

Validation of Alternative Methods Collection

Article 23 of European Union (EU) Directive 86/609/EEC required that Member States promote the development and validation of alternative technologies and stated that the European Commission (EC) “shall report before the end of 1987 on the possibility of modifying tests and guidelines” (European Parliament, 1986, Article 23). This Directive was replaced by Directive 2010/63/EU on the protection of animals used for scientific purposes, which now requires that Member States develop and validate alternative approaches much more precisely and specifies that the ultimate objective is the “full replacement of procedures on live animals for scientific and educational purposes, as soon as …

Cronbach’S Alpha Under Insufficient Effort Responding: An Analytic Approach, Stephen W. Carden, Trevor R. Camper, Nicholas S. Holtzman

Department of Psychology Faculty Publications

Surveys commonly suffer from insufficient effort responding (IER). If not accounted for, IER can cause biases and lead to false conclusions. In particular, Cronbach’s alpha has been empirically observed to either deflate or inflate due to IER. This paper will elucidate how IER impacts Cronbach’s alpha in a variety of situations. Previous results concerning internal consistency under mixture models are extended to obtain a characterization of Cronbach’s alpha in terms of item validities, average variances, and average covariances. The characterization is then applied to contaminating distributions representing various types of IER. The discussion will provide commentary on previous simulation-based investigations, …

Replacing Animal Tests To Improve Safety For Humans, Kathy Archibald, Robert Coleman, Tamara Drake

Application of Alternative Methods Collection

In this chapter, we propose a new, pragmatic approach that could accelerate the replacement of most, if not all, regulatory animal tests with superior tests based on human biology. We also propose that changes to the requirements for safety testing, issued by the us Food and Drug Administration (fda), must be made in order to enable the use of superior new tests, which are currently disadvantaged by the outdated language of the regulations. But first, it is imperative to establish some level of understanding of the efficacy of existing animal-based methods in order to know whether any possible replacement is …