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Full-Text Articles in Statistics and Probability

Mesenchymal Stem Cells In Autoimmune Disease: A Systematic Review And Meta-Analysis Of Pre-Clinical Studies, Hailey N. Swain, Parker D. Boyce, Bradley A. Bromet, Kaiden Barozinksy, Lacy Hance, Dakota Shields, Gayla R. Olbricht, Julie A. Semon Aug 2024

Mesenchymal Stem Cells In Autoimmune Disease: A Systematic Review And Meta-Analysis Of Pre-Clinical Studies, Hailey N. Swain, Parker D. Boyce, Bradley A. Bromet, Kaiden Barozinksy, Lacy Hance, Dakota Shields, Gayla R. Olbricht, Julie A. Semon

Mathematics and Statistics Faculty Research & Creative Works

Mesenchymal Stem Cells (MSCs) Are of Interest in the Clinic Because of their Immunomodulation Capabilities, Capacity to Act Upstream of Inflammation, and Ability to Sense Metabolic Environments. in Standard Physiologic Conditions, They Play a Role in Maintaining the Homeostasis of Tissues and Organs; However, there is Evidence that They Can Contribute to Some Autoimmune Diseases. Gaining a Deeper Understanding of the Factors that Transition MSCs from their Physiological Function to a Pathological Role in their Native Environment, and Elucidating Mechanisms that Reduce their Therapeutic Relevance in Regenerative Medicine, is Essential. We Conducted a Systematic Review and Meta-Analysis of Human MSCs …


A Kinetic Model For Blood Biomarker Levels After Mild Traumatic Brain Injury, Sima Azizi, Daniel B. Hier, Blaine Allen, Tayo Obafemi-Ajayi, Gayla R. Olbricht, Matthew S. Thimgan, Donald C. Wunsch Jul 2021

A Kinetic Model For Blood Biomarker Levels After Mild Traumatic Brain Injury, Sima Azizi, Daniel B. Hier, Blaine Allen, Tayo Obafemi-Ajayi, Gayla R. Olbricht, Matthew S. Thimgan, Donald C. Wunsch

Mathematics and Statistics Faculty Research & Creative Works

Traumatic brain injury (TBI) imposes a significant economic and social burden. The diagnosis and prognosis of mild TBI, also called concussion, is challenging. Concussions are common among contact sport athletes. After a blow to the head, it is often difficult to determine who has had a concussion, who should be withheld from play, if a concussed athlete is ready to return to the field, and which concussed athlete will develop a post-concussion syndrome. Biomarkers can be detected in the cerebrospinal fluid and blood after traumatic brain injury and their levels may have prognostic value. Despite significant investigation, questions remain as …


Student Preclass Preparation By Both Reading The Textbook And Watching Videos Online Improves Exam Performance In A Partially Flipped Course, Kaleb Bassett, Gayla R. Olbricht, Katie Shannon Sep 2020

Student Preclass Preparation By Both Reading The Textbook And Watching Videos Online Improves Exam Performance In A Partially Flipped Course, Kaleb Bassett, Gayla R. Olbricht, Katie Shannon

Mathematics and Statistics Faculty Research & Creative Works

The flipped classroom has the potential to improve student performance. Because flipping involves both preclass preparation and problem solving in the classroom, the means by which increased learning occurs and whether the method of delivering content matters is of interest. In a partially flipped cell biology course, students were assigned online videos before the flipped class and textbook reading before lectures. Low-stakes assessments were used to incentivize both types of preclass preparation. We hypothesized that more students would watch the videos than read the textbook and that both types of preparation would positively affect exam performance. A multiple linear regression …


Birth Mass Is The Key To Understanding The Negative Correlation Between Lifespan And Body Size In Dogs, Rong Fan, Gayla R. Olbricht, Xavior Baker, Chen Hou Dec 2016

Birth Mass Is The Key To Understanding The Negative Correlation Between Lifespan And Body Size In Dogs, Rong Fan, Gayla R. Olbricht, Xavior Baker, Chen Hou

Mathematics and Statistics Faculty Research & Creative Works

Larger dog breeds live shorter than the smaller ones, opposite of the mass-lifespan relationship observed across mammalian species. Here we use data from 90 dog breeds and a theoretical model based on the first principles of energy conservation and life history tradeoffs to explain the negative correlation between longevity and body size in dogs. We found that the birth/adult mass ratio of dogs scales negatively with adult size, which is different than the weak interspecific scaling in mammals. Using the model, we show that this ratio, as an index of energy required for growth, is the key to understanding why …