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Articles 1 - 6 of 6
Full-Text Articles in Physics
Zno Nanoparticles Modulate The Ionic Transport And Voltage Regulation Of Lysenin Nanochannels, Sheenah L. Bryant, Josh E. Eixenberger, Steven Rossland, Holly Apsley, Connor Hoffman, Nisha Shrestha, Michael Mchugh, Alex Punnoose, Daniel Fologea
Zno Nanoparticles Modulate The Ionic Transport And Voltage Regulation Of Lysenin Nanochannels, Sheenah L. Bryant, Josh E. Eixenberger, Steven Rossland, Holly Apsley, Connor Hoffman, Nisha Shrestha, Michael Mchugh, Alex Punnoose, Daniel Fologea
Physics Faculty Publications and Presentations
Background: The insufficient understanding of unintended biological impacts from nanomaterials (NMs) represents a serious impediment to their use for scientific, technological, and medical applications. While previous studies have focused on understanding nanotoxicity effects mostly resulting from cellular internalization, recent work indicates that NMs may interfere with transmembrane transport mechanisms, hence enabling contributions to nanotoxicity by affecting key biological activities dependent on transmembrane transport. In this line of inquiry, we investigated the effects of charged nanoparticles (NPs) on the transport properties of lysenin, a pore-forming toxin that shares fundamental features with ion channels such as regulation and high transport rate.
Results: …
Ribonucleoprotein Purification And Characterization Using Rna Mango, Shanker Shyam S. Panchapakesan, Matthew L. Ferguson, Eric J. Hayden, Xin Chen, Aaron A. Hoskins, Peter J. Unrau
Ribonucleoprotein Purification And Characterization Using Rna Mango, Shanker Shyam S. Panchapakesan, Matthew L. Ferguson, Eric J. Hayden, Xin Chen, Aaron A. Hoskins, Peter J. Unrau
Physics Faculty Publications and Presentations
The characterization of RNA–protein complexes (RNPs) is a difficult but increasingly important problem in modern biology. By combining the compact RNA Mango aptamer with a fluorogenic thiazole orange desthiobiotin (TO1-Dtb or TO3-Dtb) ligand, we have created an RNA tagging system that simplifies the purification and subsequent characterization of endogenous RNPs. Mango-tagged RNP complexes can be immobilized on a streptavidin solid support and recovered in their native state by the addition of free biotin. Furthermore, Mango-based RNP purification can be adapted to different scales of RNP isolation ranging from pull-down assays to the isolation of large amounts of biochemically defined cellular …
Estimates For The Number Of Visible Galaxy-Spanning Civilizations And The Cosmological Expansion Of Life, S. Jay Olson
Estimates For The Number Of Visible Galaxy-Spanning Civilizations And The Cosmological Expansion Of Life, S. Jay Olson
Physics Faculty Publications and Presentations
If advanced civilizations appear in the universe with an ability and desire to expand, the entire universe can become saturated with life on a short timescale, even if such expanders appear rarely. Our presence in an apparently untouched Milky Way thus constrains the appearance rate of galaxyspanning Kardashev type III (K3) civilizations, if it is assumed that some fraction of K3 civilizations will continue their expansion at intergalactic distances. We use this constraint to estimate the appearance rate of K3 civilizations for 81 cosmological scenarios by specifying the extent to which humanity is a statistical outlier. We find that in …
A New Model Of Roche-Lobe Overflow For Short-Period Gaseous Planets And Binary Stars, Brian Jackson, Phil Arras, Kaloyan Penev, Sarah Peacock, Pablo Marchant
A New Model Of Roche-Lobe Overflow For Short-Period Gaseous Planets And Binary Stars, Brian Jackson, Phil Arras, Kaloyan Penev, Sarah Peacock, Pablo Marchant
Physics Faculty Publications and Presentations
Some close-in gaseous exoplanets are nearly in Roche-lobe contact, and previous studies show tidal decay can drive hot Jupiters into contact during the main sequence of their host stars. Improving upon a previous model, we present a revised model for mass transfer in a semi-detached binary system that incorporates an extended atmosphere around the donor and allows for an arbitrary mass ratio. We apply this new formalism to hypothetical, confirmed, and candidate planetary systems to estimate mass loss rates and compare with models of evaporative mass loss. Overflow may be significant for hot Neptunes out to periods of ∼ 2 …
Ultra Short Period Planets In K2 With Companions: A Double Transiting System For Epic 220674823, Brian Jackson
Ultra Short Period Planets In K2 With Companions: A Double Transiting System For Epic 220674823, Brian Jackson
Physics Faculty Publications and Presentations
Two transiting planets have been identified orbiting K2 target EPIC 220674823. One object is an ultra-short-period planet (USP) with a period of just 0.57 days (13.7 hours), while the other has a period of 13.3 days. Both planets are small, with the former having a radius of Rp1 = 1.5 R⊕ and the latter Rp2 = 2.5 R⊕. Follow-up observations, including radial velocity (with uncertainties of 110 ms−1) and high-resolution adaptive optics imagery, show no signs of stellar companions. EPIC 220674823 is the 12th confirmed or validated planetary system in which an …
Review Article: Molecular Beam Epitaxy Of Lattice-Matched Inalas And Ingaas Layers On Inp (111)A, (111)B, And (110), Christopher D. Yerino, Baolai Liang, Diana L. Huffaker, Paul J. Simmonds, Minjoo Larry Lee
Review Article: Molecular Beam Epitaxy Of Lattice-Matched Inalas And Ingaas Layers On Inp (111)A, (111)B, And (110), Christopher D. Yerino, Baolai Liang, Diana L. Huffaker, Paul J. Simmonds, Minjoo Larry Lee
Physics Faculty Publications and Presentations
For more than 50 years, research into III–V compound semiconductors has focused almost exclusively on materials grown on (001)-oriented substrates. In part, this is due to the relative ease with which III–Vs can be grown on (001) surfaces. However, in recent years, a number of key technologies have emerged that could be realized, or vastly improved, by the ability to also grow high-quality III–Vs on (111)- or (110)-oriented substrates These applications include: next-generation field-effect transistors, novel quantum dots, entangled photon emitters, spintronics, topological insulators, and transition metal dichalcogenides. The first purpose of this paper is to present a comprehensive review …