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Full-Text Articles in Physics
Propagating Conformational Changes Over Long (And Short) Distances In Proteins, Edward Yu, Daniel E. Koshland Jr.
Propagating Conformational Changes Over Long (And Short) Distances In Proteins, Edward Yu, Daniel E. Koshland Jr.
Edward Yu
The problem of the propagation of conformational changes over long distances or through a closely packed protein is shown to fit a model of a ligand-induced conformational change between two protein states selected by evolution. Moreover, the kinetics of the pathway between these states is also selected so that the energy of ligand binding and the speed of the transition between conformational states are physiologically appropriate. The crystallographic data of a wild-type aspartate receptor that has negative cooperativity and a mutant that has no cooperativity but has native transmembrane signaling are shown to support this model.
Synthesis And Characterization Of A New Class Of Μ3-Oh-Bridged Trimers That Contain Octahedrally Coordinated Divalent Metal Ions Bridged By Three Acetate Ligands And A Unique Catecholate Ligand. Solid State Molecular Structures Of The [(Py)5mii3(Oac)3(Μ3-Oh)((Cat)] Complexes (M = Mn(Ii), Fe(Ii), Co(Ii), Ni(Ii)), R.A. Reynolds, Edward Yu, W.R. Dunham, D. Coucouvanis
Synthesis And Characterization Of A New Class Of Μ3-Oh-Bridged Trimers That Contain Octahedrally Coordinated Divalent Metal Ions Bridged By Three Acetate Ligands And A Unique Catecholate Ligand. Solid State Molecular Structures Of The [(Py)5mii3(Oac)3(Μ3-Oh)((Cat)] Complexes (M = Mn(Ii), Fe(Ii), Co(Ii), Ni(Ii)), R.A. Reynolds, Edward Yu, W.R. Dunham, D. Coucouvanis
Edward Yu
The synthesis and structural characterization of a new class of “basic” trinuclear acetate clusters with solely divalent metal ions and a central μ3-OH ligand are reported. These molecules with the [(py)5MII3(OAc)3(μ3-OH)(cat)] stoichiometry (M = Mn, Fe, Co, Ni) are X-ray isomorphous and isostructural and contain octahedrally coordinated metal ions. The core consists of an antiferromagnetically coupled M3 unit with the metals arranged in the corners of an isosceles triangle. Two of the M−M distances vary between 2.98 and 3.16 Å, and the longer M−M distance is observed between 3.65 and 3.76 Å. As expected from the relative ionic radius lengths, …
Absolute Integrated Cross Sections For Some O2 Herzberg I Transitions Near 248–249 Nm, Zhen-Chuan Bao, Edward Yu, John R. Baker
Absolute Integrated Cross Sections For Some O2 Herzberg I Transitions Near 248–249 Nm, Zhen-Chuan Bao, Edward Yu, John R. Baker
Edward Yu
A frequency doubled tunable dye laser system with ∼0.4 cm−1 resolution was used to measure the integrated absorption cross sections of more than 20 rotational transitions in the O2 Herzberg I (A 3Σ+ u ←X 3Σ− g ) 8‐0 and 9‐0 vibrational bands near 248 nm and 249 nm. Oxygen pressures from 200 to 800 Torr and path lengths from 5 to 25 m were employed. The measured absorbances were fitted using a nonlinear least squares analysis and Beer’s Law to obtain absolute values for the individual transition integrated cross sections in good agreement with a recent spectral simulation and …