Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Optics (87)
- Engineering (50)
- Atomic, Molecular and Optical Physics (48)
- Biological and Chemical Physics (48)
- Medicine and Health Sciences (44)
-
- Life Sciences (34)
- Mathematics (32)
- Plasma and Beam Physics (31)
- Applied Mathematics (26)
- Fluid Dynamics (22)
- Analytical, Diagnostic and Therapeutic Techniques and Equipment (21)
- Electrical and Computer Engineering (21)
- Biochemistry, Biophysics, and Structural Biology (20)
- Chemistry (17)
- Condensed Matter Physics (17)
- Nuclear (13)
- Other Physics (12)
- Partial Differential Equations (12)
- Elementary Particles and Fields and String Theory (9)
- Engineering Physics (9)
- Pharmacology, Toxicology and Environmental Health (9)
- Astrophysics and Astronomy (8)
- Diagnosis (8)
- Food Science (8)
- Non-linear Dynamics (8)
- Applied Mechanics (7)
- Materials Chemistry (7)
- Mechanical Engineering (7)
- Institution
- Keyword
-
- Physics (27)
- Raman spectroscopy (23)
- Holography (19)
- Photopolymers (17)
- Ultrasound (12)
-
- Photopolymer (10)
- Raman Spectroscopy (10)
- Vibrational spectroscopy (7)
- Cytotoxicity (6)
- Holographic recording (6)
- KdV equation (6)
- Methods (6)
- Eddies (5)
- Holographic gratings (5)
- Nanomedicine (5)
- Oral cancer (5)
- Partial Least Squares Regression (5)
- Scattering (5)
- Sensors (5)
- Stokes flow (5)
- Atomic data (4)
- Beta-decay (4)
- Centrifugal filtration (4)
- Doxorubicin (4)
- Fluid dynamics (4)
- High frequency (4)
- Holographic sensors (4)
- In vitro screening (4)
- Infrared spectroscopy (4)
- Nanoparticles (4)
- Publication Year
Articles 31 - 60 of 388
Full-Text Articles in Physics
The Prospect Of Microwave Heating: Towards A Faster And Deeper Crack Healing In Asphalt Pavement, Shi Xu, Xueyan Liu, Amir Tabakovic, Erik Schlangen
The Prospect Of Microwave Heating: Towards A Faster And Deeper Crack Healing In Asphalt Pavement, Shi Xu, Xueyan Liu, Amir Tabakovic, Erik Schlangen
Articles
Microwave heating has been shown to be an effective method of heating asphalt concrete and in turn healing the damage. As such, microwave heating holds great potential in rapid (1–3 min) and effective damage healing, resulting in improvement in the service life, safety, and sustainability of asphalt pavement. This study focused on the microwave healing effect on porous asphalt concrete. Steel wool fibres were incorporated into porous asphalt to improve the microwave heating efficiency, and the optimum microwave heating time was determined. Afterwards, the microwave healing efficiency was evaluated using a semi–circular bending and healing programme. The results show that …
Diagnostics Of A Large Volume Pin-To-Plate Atmospheric Plasma Source For The Study Of Plasma Species Interactions With Cancer Cell Cultures, Laurence Scally, Chaitanya Sarangapani, Brijesh Tiwari, Renee Malone, Hugh Byrne, James Curtin, P.J. Cullen
Diagnostics Of A Large Volume Pin-To-Plate Atmospheric Plasma Source For The Study Of Plasma Species Interactions With Cancer Cell Cultures, Laurence Scally, Chaitanya Sarangapani, Brijesh Tiwari, Renee Malone, Hugh Byrne, James Curtin, P.J. Cullen
Articles
A large gap pin-to-plate, atmospheric pressure plasma reactor is demonstrated as means of in vitro study of plasma species interactions with cell cultures. By employing optical emission and optical absorption spectroscopy, we report that the pin-to-pate plasma array had an optimal discharge frequency for cell death of 1000 Hz in ambient air for the target cancer cell line; human glioblastoma multiform (U-251MG). The detected plasma chemistry contained reactive oxygen and nitrogen species including OH, N2, N2+, and O3. We show that, by varying the plasma discharge frequency, the plasma chemistry can be tailored …
Impact Of Dynamic Sub-Populations Within Grafted Chains On The Protein Binding And Colloidal Stability Of Pegylated Nanoparticles, Delyan Hristov, Hender Lopez, Yannick Ortin, Kate O'Sullivan, Kenneth A. Dawson, Dermot F. Brougham
Impact Of Dynamic Sub-Populations Within Grafted Chains On The Protein Binding And Colloidal Stability Of Pegylated Nanoparticles, Delyan Hristov, Hender Lopez, Yannick Ortin, Kate O'Sullivan, Kenneth A. Dawson, Dermot F. Brougham
Articles
Polyethylene glycol grafting has played a central role in preparing the surfaces of nano-probes for biological interaction, to extend blood circulation times and to modulate protein recognition and cellular uptake. However, the role of PEG graft dynamics and conformation in determining surface recognition processes is poorly understood primarily due to the absence of a microscopic picture of the surface presentation of the polymer. Here a detailed NMR analysis reveals three types of dynamic ethylene glycol units on PEG-grafted SiO2 nanoparticles (NPs) of the type commonly evaluated as long-circulating theranostic nano-probes; a narrow fraction with fast dynamics associated with the chain …
The Potential Of Raman Spectroscopy In The Diagnosis Of Dysplastic And Malignant Oral Lesions, Ola Ibrahim, M. Toner, Steven Flint, Hugh Byrne, Fiona Lyng
The Potential Of Raman Spectroscopy In The Diagnosis Of Dysplastic And Malignant Oral Lesions, Ola Ibrahim, M. Toner, Steven Flint, Hugh Byrne, Fiona Lyng
Articles
Early diagnosis, treatment and/or surveillance of oral premalignant lesions are important in preventing progression to oral squamous cell carcinoma (OSCC). The current gold standard is through histopathological diagnosis, which is limited by inter and intra observer and sampling errors. The objective of this work was to use Raman spectroscopy to discriminate between benign, mild, moderate and severe dysplasia and OSCC in formalin fixed paraffin preserved (FFPP) tissues. The study included 72 different pathologies from which 17 were benign lesions, 20 mildly dysplastic, 20 moderately dysplastic, 10 severely dysplastic and 5 invasive OSCC. The glass substrate and paraffin wax background were …
Biomedical Applications Of Vibrational Spectroscopy: Oral Cancer Diagnostics, Hugh Byrne, Isha Behl, Genecy Calado, Ola Ibrahim, M. Toner, Sheila Galvin, Claire M. Healy, Steven Flint, Fiona Lyng
Biomedical Applications Of Vibrational Spectroscopy: Oral Cancer Diagnostics, Hugh Byrne, Isha Behl, Genecy Calado, Ola Ibrahim, M. Toner, Sheila Galvin, Claire M. Healy, Steven Flint, Fiona Lyng
Articles
Vibrational spectroscopy, based on either infrared absorption or Raman scattering, has attracted increasing attention for biomedical applications. Proof of concept explorations for diagnosis of oral potentially malignant disorders and cancer are reviewed, and recent advances critically appraised. Specific examples of applications of Raman microspectroscopy for analysis of histological, cytological and saliva samples are presented for illustrative purposes, and the future prospects, ultimately for routine, chairside in vivo screening are discussed.
Combined Experimental And Modeling Analysis For Thedevelopment Of Optical Materials Suitable To Enhance Theimplementation Of Plasmonic-Enhanced Luminescent Down-Shifting Solutions On Existing Silicon-Based Photovoltaic Devices, James Walshe, Mihaela Girtan, Sarah Mccormack, John Doran, George Amarandei
Combined Experimental And Modeling Analysis For Thedevelopment Of Optical Materials Suitable To Enhance Theimplementation Of Plasmonic-Enhanced Luminescent Down-Shifting Solutions On Existing Silicon-Based Photovoltaic Devices, James Walshe, Mihaela Girtan, Sarah Mccormack, John Doran, George Amarandei
Articles
The development of highly efficient solar collectors requires modulating the light interactions with the semiconducting materials. Incorporating luminescent species and metal nanoparticles within a semitransparent polymeric material (e.g., polymethyl methacrylate (PMMA)) leads to the formation of a plasmon-enhanced luminescent down-shifting (PLDS) layer, which offers a retrofittable approach toward expanding the wavelength range over which the conversion process can effectively occur. Adding antireflection coatings (ARCs) further controls the spectral response. However, with each additional component comes additional loss pathways. In this study, the losses related to light interactions with the PMMA and the ARCs have been investigated theoretically using a transfer …
Optimisation Of Retrofit Wall Insulation: An Irish Case Study, Rakshit D. Muddu, D M. Gowda, Anthony James Robinson, Aimee Byrne
Optimisation Of Retrofit Wall Insulation: An Irish Case Study, Rakshit D. Muddu, D M. Gowda, Anthony James Robinson, Aimee Byrne
Articles
Ireland has one of the highest rates of emissions per capita in the world and its residential sector is responsible for approximately 10% of total national CO2 emissions. Therefore, reducing the CO2 emissions in this sector will play a decisive role in achieving EU targets of reducing emissions by 40% by 2030. To better inform decisions regarding retrofit of the existing building stock, this study proposes Optimum Insulation Thicknesses (OIT) for typical walls in 25 regions in Ireland. The calculation of OIT includes annual heat energy expenditure, CO2 emissions, and material payback period. The approach taken is based on Heating …
Monitoring Stem Cell Differentiation Using Raman Microspectroscopy: Chondrogenic Differentiation, Towards Cartilage Formation, Francesca Ravera, Esen Efeoglu, Hugh Byrne
Monitoring Stem Cell Differentiation Using Raman Microspectroscopy: Chondrogenic Differentiation, Towards Cartilage Formation, Francesca Ravera, Esen Efeoglu, Hugh Byrne
Articles
Mesenchymal Stem Cells (MSCs) have the ability to differentiate into chondrocytes, the only cellular components of cartilage and are therefore ideal candidates for cartilage and tissue repair technologies. Chondrocytes are surrounded by cartilage-like extracellular matrix (ECM), a complex network rich in glycosaminoglycans, proteoglycans, and collagen, which, together with a multitude of intracellular signalling molecules, trigger the chondrogenesis and allow the chondroprogenitor to acquire the spherical morphology of the chondrocytes. However, although the mechanisms of the differentiation of MSCs have been extensively explored, it has been difficult to provide a holistic picture of the process, in situ. Raman Micro Spectroscopy (RMS) …
Semiclassical Backreaction On Asymptotically Anti–De Sitter Black Holes, Peter Taylor, Cormac Breen
Semiclassical Backreaction On Asymptotically Anti–De Sitter Black Holes, Peter Taylor, Cormac Breen
Articles
We consider a quantum scalar field on the classical background of an asymptotically anti–de Sitter black hole and the backreaction the field’s stress-energy tensor induces on the black hole geometry. The backreaction is computed by solving the reduced-order semiclassical Einstein field equations sourced by simple analytical approximations for the renormalized expectation value of the scalar field stress-energy tensor. When the field is massless and conformally coupled, we adopt Page’s approximation to the renormalized stress-energy tensor, while for massive fields we adopt a modified version of the DeWitt-Schwinger approximation. The latter approximation must be modified so that it possesses the correct …
Acute Growth Inhibition & Toxicity Analysis Of Nano-Polystyrene Spheres On Raphidocelis Subcapitata, Anthony Reynolds, Michelle Giltrap, Gordon Chambers
Acute Growth Inhibition & Toxicity Analysis Of Nano-Polystyrene Spheres On Raphidocelis Subcapitata, Anthony Reynolds, Michelle Giltrap, Gordon Chambers
Articles
Micro/nano-plastics (MNPs) have been found within many environments and organisms including humans, making them a significant and growing concern. Initial research into the potential detrimental effects these MNPs both from acute and chronic exposure has been ongoing but still requires substantially more data to clarify. This research presents the response of nano-polystyrene (NPS) on Raphidocelis subcapitata, a freshwater alga, under an existing acute toxicity test along with additional analytical techniques to try identifying possible sources of toxicity. R. subcapitata cells were exposed for 72 h to a concentration range of 0–100 mg/l NPS. Growth Inhibition (GI) testing showed the …
Five-Wave Resonances In Deep Water Gravity Waves: Integrability, Numerical Simulations And Experiments, Dan Lucas, Marc Perlin, Dian-Yong Liu, Shane Walsh, Rossen Ivanov, Miguel D. Bustamante
Five-Wave Resonances In Deep Water Gravity Waves: Integrability, Numerical Simulations And Experiments, Dan Lucas, Marc Perlin, Dian-Yong Liu, Shane Walsh, Rossen Ivanov, Miguel D. Bustamante
Articles
In this work we consider the problem of finding the simplest arrangement of resonant deep water gravity waves in one-dimensional propagation, from three perspectives: Theoretical, numerical and experimental. Theoretically this requires using a normal-form Hamiltonian that focuses on 5-wave resonances. The simplest arrangement is based on a triad of wave vectors K1 + K2 = K3 (satisfying specific ratios) along with their negatives, corresponding to a scenario of encountering wave packets, amenable to experiments and numerical simulations. The normal-form equations for these encountering waves in resonance are shown to be non-integrable, but they admit an integrable reduction …
Evaluation Of Postoperative Refractive Error Correction After Cataract Surgery, Ellen Konadu Antwi-Adjei, Emmanuel Owusu, Emmanuel Kobia-Acquah, Emmanuella Esi Dadzie, Emmanuel Anarfi, Seth Wanye
Evaluation Of Postoperative Refractive Error Correction After Cataract Surgery, Ellen Konadu Antwi-Adjei, Emmanuel Owusu, Emmanuel Kobia-Acquah, Emmanuella Esi Dadzie, Emmanuel Anarfi, Seth Wanye
Articles
Suboptimal cataract surgery outcomes remain a challenge in most developing countries. In Ghana, about 2 million people have been reported to be blind due to cataract with about 20% new cases being recorded yearly. The aim of this study was to evaluate postoperative correction of refractive errors after cataract surgery in a selected eye hospital in Ashanti Region, Ghana. This was a retrospective study where medical records of patients (aged 40–100) who reported to an eye hospital in Ghana from 2013–2018 were reviewed. Included in the study were patients aged ≥40 years and patients with complete records. Data on patient …
Enhancing The Visibility Of Vernier Effect In A Tri-Microfiber Coupler Fiber Loop Interferometer For Ultrasensitive Refractive Index And Temperature Sensing, Fangfang Wei, Dejun Liu, Zhe Wang, Zhuochen Wang, Gerald Farrell, Qiang Wu, Gang-Ding Peng, Yuliya Semenova
Enhancing The Visibility Of Vernier Effect In A Tri-Microfiber Coupler Fiber Loop Interferometer For Ultrasensitive Refractive Index And Temperature Sensing, Fangfang Wei, Dejun Liu, Zhe Wang, Zhuochen Wang, Gerald Farrell, Qiang Wu, Gang-Ding Peng, Yuliya Semenova
Articles
In this paper a Vernier effect based sensor is analyzed and demonstrated experimentally in a tri-microfiber coupler (Tri-MFC) and polarization-maintaining fiber (PMF) loop interferometer (Tri-MFC-PMF) to provide ultrasensitive refractive index and temperature sensing. The main novelty of this work is an analysis of parameters of the proposed Tri-MFC-PMF with the objective of determining the conditions leading to a strong Vernier effect. It has been identified by simulation that the Vernier effect is a primary factor in the design of Tri-MFC-PMF loop sensing structure for sensitivity enhancement. It is furthermore demonstrated experimentally that enhancing the visibility of the Vernier spectrum in …
Can Ethanol Affect The Cell Structure - A Dynamic Molecular And Raman Spectroscopy Study, Luis Felipe Carvalho, Laurita Dos Santos, Kate O'Callaghan, Franck Bonnier, Steven Flint, Fiona Lyng, Hugh Byrne
Can Ethanol Affect The Cell Structure - A Dynamic Molecular And Raman Spectroscopy Study, Luis Felipe Carvalho, Laurita Dos Santos, Kate O'Callaghan, Franck Bonnier, Steven Flint, Fiona Lyng, Hugh Byrne
Articles
The role that tobacco consumption plays in the etiology of oral cancer carcinogenesis, and of alcohol consumption acting as a co-factor, have been well established. However, in recent years, the contribution of alcohol consumption alone to oral cancer has been proposed. In fact, a high percentage of patients who develop oral cancer have both habits (tobacco and alcohol consumption), and other small patient groups only consume alcohol or do not have any other identifiable bad habits. In the present study, we demonstrate for the first time, using a combination of dynamic molecular modelling and Raman spectroscopy, that ethanol has a …
Quantitative Analysis Of Human Blood Serum Using Vibrational Spectroscopy., Hugh Byrne, Franck Bonnier, Jennifer Mcintyre, Drishya Rajan Parachalil
Quantitative Analysis Of Human Blood Serum Using Vibrational Spectroscopy., Hugh Byrne, Franck Bonnier, Jennifer Mcintyre, Drishya Rajan Parachalil
Articles
Analysis of bodily fluids using vibrational spectroscopy has attracted increasing attention in recent years. In particular, infrared spectroscopic screening of blood products, particularly blood serum, for disease diagnostics has been advanced considerably, attracting commercial interests. However, analyses requiring quantification of endogenous constituents or exogenous agents in blood are less well advanced. Recent advances towards this end are reviewed, focussing on infrared and Raman spectroscopic analyses of human blood serum. The importance of spectroscopic analysis in the native aqueous environment is highlighted, and the relative merits of infrared absorption versus Raman spectroscopy are considered, in this context. It is argued that …
Liposomal Encapsulation Of Silver Nanoparticles (Agnp) Improved Nanoparticle Uptake And Induced Redox Imbalance To Activate Caspase-Dependent Apoptosis, Azeez Yusuf, Alan Casey
Liposomal Encapsulation Of Silver Nanoparticles (Agnp) Improved Nanoparticle Uptake And Induced Redox Imbalance To Activate Caspase-Dependent Apoptosis, Azeez Yusuf, Alan Casey
Articles
Macrophages play a crucial role in several diseases’ development and progression, such as in cancer and arthritis through ROS generation and infammation. This makes macrophages a therapeutic target in these diseases. While silver nanoparticles (AgNP) have been widely used as an antibacterial and investigated as anticancer, its potential against macrophages may be limited due to its inherent oxidative mechanism. Here we encapsulated AgNP in a dipalmitoyl-phosphatidyl choline (DPPC) liposome (forming Lipo-AgNP) to suppress AgNP-induced ROS and enhance its cytotoxicity against THP1-diferentiated macrophages (TDM). Our fndings showed that while Lipo-AgNP had signifcantly more of a cytotoxic efect on TDMs (p<0.01), it also signifcantly suppressed AgNP induced ROS generation and unexpectedly suppressed reduced glutathione (GSH) levels (p<0.05) resulting in a redox imbalance in comparison to the unexposed control TDMs. Lipo-AgNP was also found to cause an increase DNA damage through H2AX histone phosphorylation and inhibition of Bcl-2 protein expression. This increased the Bax/Bcl2 ratio causing possible release of cytochrome C and subsequent caspase 3/7-dependent apoptosis. It was found that the diference between the mechanism of AgNP and Lipo-AgNP cytotoxicity may have been through the signifcantly increased Lipo-AgNP uptake by the TDMs as early as 30 min post-exposure (p<0.05), changing the nanoparticle pharmacokinetic. In conclusion, the improved uptake of AgNP within the liposome caused ROS-independent caspase activation induced by Lipo-AgNP and this was facilitated by increased DNA damage, the induced redox imbalance and an increased Bax/Bcl-2 ratio.
High-Sensitivity Temperature Sensor Based On Anti-Resonance In High-Index Polymer-Coated Optical Fiber Interferometers, Xiaokang Lian, Qiang Wu, Gerald Farrell, Yuliya Semenova
High-Sensitivity Temperature Sensor Based On Anti-Resonance In High-Index Polymer-Coated Optical Fiber Interferometers, Xiaokang Lian, Qiang Wu, Gerald Farrell, Yuliya Semenova
Articles
Compared to the multimode interference (MMI) effect, the anti-resonance (AR) effect does not rely on the multimode property of the optical waveguide. This Letter shows that fiber bending can suppress the MMI and can break the superposition of AR spectra of multiple modes in a high-index polymer-coated optical fiber interferometer based on a single-mode fiber-polymer-coated no-core fiber-single-mode fiber hetero-structure. This results in the dominance of the AR spectrum of an individual mode and consequently in periodic sharp transmission dips. As a result of this phenomenon and large thermo-optical and thermal expansion coefficients of the polymer, a compact, high-sensitivity and linear …
Simultaneous Measurement Of Displacement And Temperature Based On Two Cascaded Balloon-Like Bent Fibre Structures, Ke Tian, Ruoning Wang, Meng Zhang, Xiafan Wang, Xin Wang, Guoyong Jin, Elfed Lewis, Gerald Farrell, Pengfei Wang
Simultaneous Measurement Of Displacement And Temperature Based On Two Cascaded Balloon-Like Bent Fibre Structures, Ke Tian, Ruoning Wang, Meng Zhang, Xiafan Wang, Xin Wang, Guoyong Jin, Elfed Lewis, Gerald Farrell, Pengfei Wang
Articles
A low-cost optical fibre sensor based on two cascaded balloon-like bent fibre (BBF) structures for simultaneous displacement and temperature measurement is reported. The sensor is fabricated by cascading two balloon-like bent single-mode fibres (SMFs) which with different bending radii, generating two separate interference dips within a limited wavelength range. The wavelength of the two interference dips exhibits different responses to external displacement and temperature variations, hence simultaneous measurement of displacement and temperature is realized. Experimental results show that the proposed optical fibre sensor achieves a displacement sensitivity of −318.8 pm/μm and a temperature sensitivity of 47.4 pm/°C. Taking advantage of …
Microfluidic Flow Direction And Rate Vector Sensor Based On A Partially Gold-Coated Tfbg, Changyu Shen, Dejun Liu, Xiaokang Lian, Tingting Lang, Chunliu Zhao, Yuliya Semenova, Jacques Albert
Microfluidic Flow Direction And Rate Vector Sensor Based On A Partially Gold-Coated Tfbg, Changyu Shen, Dejun Liu, Xiaokang Lian, Tingting Lang, Chunliu Zhao, Yuliya Semenova, Jacques Albert
Articles
In microfluidic chips applications, the monitoring of the rate and the direction of a microfluidic flow is very important. Here, we demonstrate a liquid flow rate and a direction sensor using a partially gold-coated tilted fiber Bragg grating (TFBG) as the sensing element. Wavelength shifts and amplitude changes of the TFBG transmission resonances in the near infrared reveal the direction of the liquid flowing along the fiber axis in the vicinity of the TFBG due to a nanoscale gold layer over part of the TFBG. For a device length of 10 mm (and a diameter of 125 µm for easy …
Nis2 As A Broadband Saturable Absorber For Ultrafast Pulse Lasers, Pengfei Wang, Han Zhang, Yu Yin, Qiuyun Ouyang, Yujin Chen, Elfed Lewis, Gerald Farrell, Masaki Tokurakawa, Sulaiman Wadi Harun, Cong Wang, Shi Li
Nis2 As A Broadband Saturable Absorber For Ultrafast Pulse Lasers, Pengfei Wang, Han Zhang, Yu Yin, Qiuyun Ouyang, Yujin Chen, Elfed Lewis, Gerald Farrell, Masaki Tokurakawa, Sulaiman Wadi Harun, Cong Wang, Shi Li
Articles
Nickel disulfide (NiS2) has recently been found to possess strong nonlinear saturable absorption properties. This feature is highly attractive for nonlinear photonics applications. Ultrafast pulse generation is successfully demonstrated in this article for both Ytterbium- and Erbium-doped fibre lasers using micro-fibre deposited nickel disulfide (NiS2) as a saturable absorber (SA). The fabricated SA device has a modulation depth of 23% at 1.06 μm and 30.8% at 1.55 μm. Stable dissipative soliton operation was achieved at 1064.5 nm with a pulse duration of 11.7 ps and another stable conventional soliton pulse train was also obtained at 1560.2 nm with a pulse …
Intense Mid-Infrared Emission At 3.9 Μm In Ho3+-Doped Zbya Glasses For Potential Use As A Fiber Laser, Haiyan Zhao, Ruicong Wang, Xin Wang, Shijie Jia, Yaxian Fan, Elfed Lewis, Gerald Farrell, Shunbin Wang, Pengfei Wang
Intense Mid-Infrared Emission At 3.9 Μm In Ho3+-Doped Zbya Glasses For Potential Use As A Fiber Laser, Haiyan Zhao, Ruicong Wang, Xin Wang, Shijie Jia, Yaxian Fan, Elfed Lewis, Gerald Farrell, Shunbin Wang, Pengfei Wang
Articles
Intense mid-infrared emission at 3.9 µm in Ho3+-doped ZBYA glasses with direct upper laser level (Ho3+ : 5 I5) pumping at a wavelength of 888 nm is reported for the first time, to the best of our knowledge. Spectroscopic parameters were determined using the Judd–Ofelt theory and the measured absorption spectrum. The maximum emission cross section of the Ho3+-doped ZBYA glass is estimated to be 2.7 × 10−21 cm2 at 3906 nm. Additionally, fluorescence spectra and lifetimes of ZBYA glasses with different Ho3+ ion doping concentrations were measured. The results provide theoretical and experimental basis for better selection of rare-earth-doped …
Stacked Volume Holographic Gratings For Extending The Operational Wavelength Range In Led And Solar Applications, Sanjay Keshri, Julia Marín-Sáez, Izabela Naydenova, Kevin Murphy, Jesús Atencia, Daniel Chemisana, Sean Garner, María-Victoria Collados, Suzanne Martin
Stacked Volume Holographic Gratings For Extending The Operational Wavelength Range In Led And Solar Applications, Sanjay Keshri, Julia Marín-Sáez, Izabela Naydenova, Kevin Murphy, Jesús Atencia, Daniel Chemisana, Sean Garner, María-Victoria Collados, Suzanne Martin
Articles
A novel stacking procedure is presented for volume phase holographic gratings (VPHGs) recorded in photopolymer material using Corning Willow Glass as a flexible substrate in order to achieve broader angular and spectral selectivity in a diffractive device with high efficiency for solar and LED applications. For the first time to our knowledge, we have shown a device designed for use with a white LED that has the same input and output angles and high efficiency when illuminated by different wavelengths. In this paper, two VPHGs were designed, experimentally recorded, and tested when illuminated at normal incidence. The experimental approach is …
Silicon Microcantilever Sensors To Detect The Reversible Conformational Change Of A Molecular Switch, Spiropyan, Catherine M. Grogan, George Amarandei, Shauna Lawless, Francis Pedreschi, Fiona Lyng, Fernando Benito-Lopez, Roberto Raiteri, Laisa Florea
Silicon Microcantilever Sensors To Detect The Reversible Conformational Change Of A Molecular Switch, Spiropyan, Catherine M. Grogan, George Amarandei, Shauna Lawless, Francis Pedreschi, Fiona Lyng, Fernando Benito-Lopez, Roberto Raiteri, Laisa Florea
Articles
The high sensitivity of silicon microcantilever sensors has expanded their use in areas ranging from gas sensing to bio-medical applications. Photochromic molecules also represent promising candidates for a large variety of sensing applications. In this work, the operating principles of these two sensing methods are combined in order to detect the reversible conformational change of a molecular switch, spiropyran. Thus, arrays of silicon microcantilever sensors were functionalized with spiropyran on the gold covered side and used as test microcantilevers. The microcantilever deflection response was observed, in five sequential cycles, as the transition from the spiropyran (SP) (CLOSED) to the merocyanine …
Towards A Rapid Screening Of Liver Grafts At The Operating Room Using Mid-Infrared Spectroscopy, David Perezguaita, Marta Moreno Torres, Ramiro Jover, Eugenia Pareja, Bernard Lendl, Julia Kuligowsky, Guillermo Quintas
Towards A Rapid Screening Of Liver Grafts At The Operating Room Using Mid-Infrared Spectroscopy, David Perezguaita, Marta Moreno Torres, Ramiro Jover, Eugenia Pareja, Bernard Lendl, Julia Kuligowsky, Guillermo Quintas
Articles
The estimation of steatosis in a liver graft is mandatory prior to liver transplantation, as the risk of graft failure increases with the level of infiltrated fat. However, the assessment of liver steatosis before transplantation is typically based on a qualitative or semiquantitative characterization by visual inspection and palpation and histological analysis. Thus, there is an unmet need for transplantation surgeons to have access to a diagnostic tool enabling an in situ fast classification of grafts prior to extraction. In this study, we have assessed an attenuated total reflection−Fourier transform infrared (ATR−FTIR) spectroscopic method compatible with the requirements of an …
Empirical Study On The Effects Of Acquisition Parameters For Ftir Hyperspectral Imaging Of Brain Tissue, David Perezguaita, Julia Sacharz, Mustafa Kasniz, Shaiju Nazeer, Bayden Wood, Philip Heraud
Empirical Study On The Effects Of Acquisition Parameters For Ftir Hyperspectral Imaging Of Brain Tissue, David Perezguaita, Julia Sacharz, Mustafa Kasniz, Shaiju Nazeer, Bayden Wood, Philip Heraud
Articles
Fourier transform infrared (FTIR) spectroscopic imaging is a powerful technique for molecular imaging of pathologies associated with the nervous systems including multiple sclerosis research. However, there is no standard methodology or standardized protocol for FTIR imaging of tissue sections that maximize the ability to discriminate between the molecular, white and granular layers, which is essential in the investigation of the mechanism of demyelination process. Tissue sections are heterogeneous, complex and delicate, hence the parameters to generate high quality images in minimal time becomes essential in the modern clinical laboratory. This article presents an FTIR spectroscopic imaging study of post-mortem human …
Discriminant Analysis And Feature Selection In Mass Spectrometry Imaging Using Constrained Repeated Random Sampling - Cross Validation (Corrs-Cv), David Perezguaita, Julia Kuligowsky, Guillermo Quintas
Discriminant Analysis And Feature Selection In Mass Spectrometry Imaging Using Constrained Repeated Random Sampling - Cross Validation (Corrs-Cv), David Perezguaita, Julia Kuligowsky, Guillermo Quintas
Articles
No abstract provided.
Birefringent Optofluidic Gratings, Sergio Calixto, Jose L. Garcia-Cordero, Diana F. Cedillo-Alcantar, Izabela Naydenova, Guillermo Garnica
Birefringent Optofluidic Gratings, Sergio Calixto, Jose L. Garcia-Cordero, Diana F. Cedillo-Alcantar, Izabela Naydenova, Guillermo Garnica
Articles
A set of parallel microfluidic channels behaving as a diffraction grating operating in the Raman-Nath regime has been fabricated and studied. The diffraction efficiency of such structure can be tuned by selecting a liquid with a particular refractive index and/or optical anisotropy. Alternatively the optical properties of the liquid can be characterised by measuring the diffraction efficiency and the state of polarization of the diffracted beam. In this work, the microfluidic channels under study have been filled with penicillin molecules dissolved in water. Due to the chirality of the penicillin, the liquid has been found to have circular birefringence of …
Investigation Of The Chemical Composition Of Plasma-Treated Water By Midiplexc And Its Antimicrobial Effect On L. Monocytogenes And Pseudomonas Fluorescens Monospecies Suspension Cultures, Oliver Handorf, Harald Below, Uta Schnabel, Katharina Riedel
Investigation Of The Chemical Composition Of Plasma-Treated Water By Midiplexc And Its Antimicrobial Effect On L. Monocytogenes And Pseudomonas Fluorescens Monospecies Suspension Cultures, Oliver Handorf, Harald Below, Uta Schnabel, Katharina Riedel
Articles
Plasma -generated compounds conceived by microwave -induced plasma (MidiPLexc) were physicochemically investigated in their molecular compositions. Therefore, plasma -treated water (PTW) was generated by treatment with the MidiPLexc within a 1 l glass bottle for a pre -treatment time of 100 s, 300 s and 900 s. The PTW was further investigated in its composition of reactive oxygen/nitrogen species. For this purpose, the hydrogen peroxide (H2O2) concentration of the PTW was determined electrochemically using chronoamperometry, and the anionic components were determined using ion chromatography. As a result, H2O2 concentrations of up to 720 mg l−1 , nitrite concentrations of 1600 …
A Catalogue Of Locus Algorithm Pointings For Optimal Differential Photometry For 23,779 Quasars, Oisın Creaner, Kevin Nolan, David Grennan, Niall Smith, Eugene Hickey
A Catalogue Of Locus Algorithm Pointings For Optimal Differential Photometry For 23,779 Quasars, Oisın Creaner, Kevin Nolan, David Grennan, Niall Smith, Eugene Hickey
Articles
This paper presents a catalogue of optimised pointings for differential photometry of23,779 quasars extracted from the Sloan Digital Sky Survey (SDSS) Catalogue and ascore for each indicating the quality of the Field of View (FoV) associated with thatpointing. Observation of millimagnitude variability on a timescale of minutes typicallyrequires differential observations with reference to an ensemble of reference stars. Foroptimal performance, these reference stars should have similar colour and magnitudeto the target quasar. In addition, the greatest quantity and quality of suitable refer-ence stars may be found by using a telescope pointing which offsets the target objectfrom the centre of the …
A Vibrational Spectroscopic Based Approach For Diagnosing Babesia Bovis Infection, Anja Ruther, David Perezguaita, William Poole, Brian Cooke, Carlos Suarez, Philip Heraud, Bayden Wood
A Vibrational Spectroscopic Based Approach For Diagnosing Babesia Bovis Infection, Anja Ruther, David Perezguaita, William Poole, Brian Cooke, Carlos Suarez, Philip Heraud, Bayden Wood
Articles
Babesia bovis parasites present a serious and significant health concern for the beef and dairy industries in many parts of the world. Difficulties associated with the current diagnostic techniques include they are prone to human error (microscopy) or expensive and time consuming (Polymerase Chain Reaction) to perform. Little is known about the biochemical changes in blood that are associated with Babesia infections. The discovery of new biomarkers will lead to improved diagnostic outcomes for the cattle industry. Vibrational spectroscopic technologies can record a chemical snapshot of the entire organism and the surrounding cell thereby providing a phenotype of the organism …