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University of Nebraska - Lincoln

2000

Robert Katz Publications

Articles 1 - 2 of 2

Full-Text Articles in Physics

Ion-Kill Dosimetry, Robert Katz, F. A. Cucinotta, M. Fromm, A. Chambaudet May 2000

Ion-Kill Dosimetry, Robert Katz, F. A. Cucinotta, M. Fromm, A. Chambaudet

Robert Katz Publications

Unanticipated late effects in neutron and heavy ion therapy, not attributable to overdose, imply a qualitative difference between low and high LET therapy. We identify that difference as ‘ion kill’, associated with the spectrum of z/β in the radiation field, whose measurement we label ‘ion-kill dosimetry’.


Track Theory Predictions For Single-Hit Cell Survival, Robert Katz, Francis Cucinotta Jan 2000

Track Theory Predictions For Single-Hit Cell Survival, Robert Katz, Francis Cucinotta

Robert Katz Publications

The track theory of cell survival after heavy-ion irradiation is based on the probability of survival after a single-particle transit, called ‘‘ion-kill’’ (not track core), joined to the cumulative effect of δ rays from adjacent ions in a beam, called ‘‘gamma-kill’’ (not penumbra). The model offers a set of equations containing four parameters, E0 and m for the single-hit multitarget statistical model for gamma-kill, and additionally σ0 and κ for ion-kill. A single set of parameters is used to fit a family of survival curves obtained with ions of different LET simultaneously.