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Design Of A Dynamic Focusing Microscope Objective For Oct Imaging, Supraja Murali
Design Of A Dynamic Focusing Microscope Objective For Oct Imaging, Supraja Murali
Electronic Theses and Dissertations
Optical Coherence Tomography (OCT) is a novel optical imaging technique that has assumed significant importance in bio-medical imaging in the last two decades because it is non-invasive and provides accurate, high resolution images of three dimensional cross-sections of body tissue, exceeding the capabilities of the current predominant imaging technique ultrasound. In this thesis, high resolution OCT is investigated for in vivo detection of abnormal skin pathology for the early diagnosis of cancer. The technology presented is based on a dynamic focusing microscopic imaging probe conceived for skin imaging and the detection of abnormalities in the epithelium. A novel method for …
System Design And Optimization Of Optical Coherence Tomography, Avni Ceyhun Akcay
System Design And Optimization Of Optical Coherence Tomography, Avni Ceyhun Akcay
Electronic Theses and Dissertations
Optical coherence imaging, including tomography (OCT) and microscopy (OCM), has been a growing research field in biomedical optical imaging in the last decade. In this imaging modality, a broadband light source, thus of short temporal coherence length, is used to perform imaging via interferometry. A challenge in optical coherence imaging, as in any imaging system towards biomedical diagnosis, is the quantification of image quality and optimization of the system components, both a primary focus of this research. We concentrated our efforts on the optimization of the imaging system from two main standpoints: axial point spread function (PSF) and practical steps …