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Full-Text Articles in Physical Sciences and Mathematics

Inhibition Of Hsv-1 Binding By Egcg-Stearate, Valerie Paschalis Jan 2019

Inhibition Of Hsv-1 Binding By Egcg-Stearate, Valerie Paschalis

Theses, Dissertations and Culminating Projects

Herpes simplex virus type 1 (HSV-1) is the causative agent of oral herpes, and is able to establish lifelong latent infection along with painful, recurring symptoms. Epigallocatechin-3- gallate (EGCG) is the most abundant polyphenol derived from green tea (Camellia sinensis), whose anti-inflammatory, antioxidant, anti-cancer, and antiviral properties have been widely studied. Although EGCG is not chemically stable and has poor hydrophobicity, lipophilic derivatives of EGCG have shown increased stability as well as increased antiviral efficacy against HSV. Previous studies have demonstrated that EGCG stearate (EGCG-S), a derivative of EGCG esterified at the 4’ position with stearic acid, is able to ...

A Latent Spatial Piecewise Exponential Model For Interval-Censored Disease Surveillance Data With Time-Varying Covariates And Misclassification, Yaxuan Sun, Chong Wang, William Q. Meeker, Max Morris, Marisa L. Rotolo, Jeffery Zimmerman Jan 2019

A Latent Spatial Piecewise Exponential Model For Interval-Censored Disease Surveillance Data With Time-Varying Covariates And Misclassification, Yaxuan Sun, Chong Wang, William Q. Meeker, Max Morris, Marisa L. Rotolo, Jeffery Zimmerman

Veterinary Diagnostic and Production Animal Medicine Publications

Understanding the dynamics of disease spread is critical to achieving effective animal disease surveillance. A major challenge in modeling disease spread is the fact that the true disease status cannot be known with certainty due to the imperfect diagnostic sensitivity and specificity of the tests used to generate the disease surveillance data. Other challenges in modeling such data include interval censoring, relating disease spread to distance between units, and incorporating time-varying covariates, which are the unobserved disease statuses. We propose a latent spatial piecewise exponential model (PEX) with misclassification of events to address the challenges in modeling such disease surveillance ...

Master’S Project: Vermont Town Forest Recreation Planning And Community Assistance Program: The Future Of Forest-Based Outdoor Recreation, Taylor M. Luneau

Rubenstein School Masters Project Publications

The Vermont Town Forest Recreation Planning Community Assistance Program (VTFRP) was a comprehensive community planning process held in ten diverse towns across Vermont. Led by the Urban and Community Forestry Program and the SE Group, the VTFRP helped towns develop a vision for the future management of their forests through open house workshops, site visits, steering committee meetings, and community surveys. The process provided towns with a forest recreation planning toolkit and an individualized action-based forest stewardship and recreation plan. By analyzing data from the community surveys and open house activities across all ten towns, my project considered the recreation ...

Diaryl Hydroxylamines As Pan Or Dual Inhibitors Of Indoleamine 2,3-Dioxygenase-1, Indoleamine 2,3-Dioxygenase-2 And Tryptophan Dioxygenase, Maria Winters, James B. Duhadaway, Khoa N. Pham, Ariel Lewis-Ballester, Shorouk Badir, Jenny Wai, Eesha Sheikh, Syun-Ru Yeh, George C. Pendergast, Alexander J. Muller, William Paul Malachowski Jan 2019

Diaryl Hydroxylamines As Pan Or Dual Inhibitors Of Indoleamine 2,3-Dioxygenase-1, Indoleamine 2,3-Dioxygenase-2 And Tryptophan Dioxygenase, Maria Winters, James B. Duhadaway, Khoa N. Pham, Ariel Lewis-Ballester, Shorouk Badir, Jenny Wai, Eesha Sheikh, Syun-Ru Yeh, George C. Pendergast, Alexander J. Muller, William Paul Malachowski

Physics Faculty Research and Scholarship

Tryptophan (Trp) catabolizing enzymes play an important and complex role in the development of cancer. Significant evidence implicates them in a range of inflammatory and immunosuppressive activities. Whereas inhibitors of indoleamine 2,3-dioxygenase-1 (IDO1) have been reported and analyzed in the clinic, fewer inhibitors have been described for tryptophan dioxygenase (TDO) and indoleamine 2,3-dioxygenase-2 (IDO2) which also have been implicated more recently in cancer, inflammation and immune control. Consequently the development of dual or pan inhibitors of these Trp catabolizing enzymes may represent a therapeutically important area of research. This is the first report to describe the development of ...

The Future Of Recreational Fisheries: Advances In Science, Monitoring, Management, And Practice, Jacob W. Brownscombe, Kieran Hyder, Warren Potts, Kyle L. Wilson, Kevin L. Pope, Andy J. Danylchuk, Steven J. Cooke, Adrian Clarke, Robert Arlinghaus, John R. Post Jan 2019

The Future Of Recreational Fisheries: Advances In Science, Monitoring, Management, And Practice, Jacob W. Brownscombe, Kieran Hyder, Warren Potts, Kyle L. Wilson, Kevin L. Pope, Andy J. Danylchuk, Steven J. Cooke, Adrian Clarke, Robert Arlinghaus, John R. Post

Nebraska Cooperative Fish & Wildlife Research Unit -- Staff Publications

Recreational fisheries (RF) are complex social-ecological systems that play an important role in aquatic environments while generating significant social and economic benefits around the world. The nature of RF is diverse and rapidly evolving, including the participants, their priorities and behaviors, and the related ecological impacts and social and economic benefits. RF can lead to negative ecological impacts, particularly through overexploitation of fish populations and spread of non-native species and genotypes through stocking. Hence, careful management and monitoring of RF is essential to sustain these ecologically and socioeconomically important resources. This special issue on recreational fisheries contains diverse research, syntheses ...

Jan 2019

Rehab Tracker: Framework For Monitoring And Enhancing Nmes Patient Compliance, Timothy Stevens

We describe the development of a cyber-physical system (Rehab Tracker) for improving patient compliance with at-home physical rehabilitation using neuromuscular electrical stimulation (NMES) therapy. Rehab Tracker consists of three components: 1) hardware modifications to sense and store use data from an FDA-approved NMES therapy device and provide Bluetooth communication capability, 2) an iOS-based smartphone/tablet application to receive and transmit NMES use data and serve as a conduit for patient-provider interactions and 3) a back-end server platform to receive device use data, display compliance data for provider review and provide automated positive and remedial push notifications to patients to improve ...

Jan 2019

Shizen Nōhō: Restoring The Relationship Between Food, Nature, And People In Japan, Katharine Graham

Scripps Senior Theses

In Japan’s postwar era, agriculture has become highly industrialized, involving heavy machinery, chemical fertilizers, and pesticides, all in the name of “progress.” Through employing such practices, humans have attempted to improve upon nature’s way of doing things, and in turn have degraded the soil’s fertility, natural ecosystems, and human health. In response to this, Shizen Nōhō has emerged in Japan as an alternative way of cultivating food. Shizen Nōhō practitioners challenge the notion that we need chemical fertilizers, pesticides, and machinery to farm successfully. Rather, they advocate for a way of growing food that functions seamlessly with ...

When Human Cognitive Modeling Meets Pins: User-Independent Inter-Keystroke Timing Attacks, Ximing Liu, Yingjiu Li, Robert H. Deng, Bing Chang, Shujun Li Jan 2019

When Human Cognitive Modeling Meets Pins: User-Independent Inter-Keystroke Timing Attacks, Ximing Liu, Yingjiu Li, Robert H. Deng, Bing Chang, Shujun Li

Research Collection School Of Information Systems

This paper proposes the first user-independent inter-keystroke timing attacks on PINs. Our attack method is based on an inter-keystroke timing dictionary built from a human cognitive model whose parameters can be determined by a small amount of training data on any users (not necessarily the target victims). Our attacks can thus be potentially launched on a large scale in real-world settings. We investigate inter-keystroke timing attacks in different online attack settings and evaluate their performance on PINs at different strength levels. Our experimental results show that the proposed attack performs significantly better than random guessing attacks. We further demonstrate that ...

Call For Abstracts - Resrb 2019, July 8-9, Wrocław, Poland, Wojciech M. Budzianowski Dec 2018

Call For Abstracts - Resrb 2019, July 8-9, Wrocław, Poland, Wojciech M. Budzianowski

Wojciech Budzianowski

No abstract provided.

Strong Equivalence And Program's Structure In Arguing Essential Equivalence Between First-Order Logic Programs, Yuliya Lierler

Yuliya Lierler

Answer set programming  is a prominent declarative programming paradigm used in formulating combinatorial search problems and implementing distinct knowledge representation formalisms. It is common that several related and yet substantially different answer set programs exist for a given problem. Sometimes these encodings may display significantly different performance. Uncovering precise formal links between these programs is often important and yet far from trivial. This paper claims the correctness   of a number of interesting program rewritings. Notably, they  assume  programs with variables and  such important language features as choice, disjunction, and aggregates. We showcase the utility of some considered rewritings  by using ...

Automatic Program Rewriting In Non-Ground Answer Set Programs, Nicholas Hippen, Yuliya Lierler Dec 2018

Automatic Program Rewriting In Non-Ground Answer Set Programs, Nicholas Hippen, Yuliya Lierler

Yuliya Lierler

Answer set programming is a popular constraint programming paradigm that has seen wide use across various industry applications. However, logic programs under answer set semantics often require careful design and nontrivial expertise from a programmer to obtain satisfactory solving times. In order to reduce this burden on a software engineer we propose an automated rewriting technique for non-ground logic programs that we implement in a system Projector. We conduct rigorous experimental analysis, which shows that applying system Projector to a logic program can improve its performance, even after significant human-performed optimizations.

Dec 2018

Side Chain Modifications To Improve Peptide Structure–Activity Relations, Neelam Lahankar

Seton Hall University Dissertations and Theses (ETDs)

While natural peptides, are ideal starting points for peptide-based drug design and development, they suffer from high conformational instability, which results in susceptibility to proteolytic degradation and poor bioavailability. Peptidomimetics in recent years has helped circumvent these shortcomings by improving the pharmacological properties of polypeptides. Peptidomimetics contain essential elements (pharmacophores) that mimic a natural peptide or protein in 3D space and retain the ability to interact with the biological target producing the same biological effect. In contrast, they offer conformationally restricted structures, potentially minimizing cross-target interactions, which leads to better transport properties through biologic membranes and resistance to immune responses ...

Theoretical Studies Of Ultrafast Electron Dynamics In Atoms And Molecules Via High-Order Harmonic Generation, Paul Abanador

The interaction of atoms and molecules with strong laser pulses is of fundamental interest in physics and chemistry. Notably, the process known as high-order harmonic generation (HHG) refers to the production of extreme-ultraviolet (XUV) light, which occurs when an ensemble of atoms or molecules is subjected to a strong infrared laser field. Characterized by an attosecond time scale (1 as = 10^-18 s), the HHG process provides the capability for experimental measurements to capture the ultrafast motion of electrons in these target atoms and molecules. The underlying physical mechanism behind this process naturally leaves imprints in the properties of the ...

My Experience Teaching General Chemistry To A Student Who Is Visually Impaired, Katherine M E Stewart Dec 2018

My Experience Teaching General Chemistry To A Student Who Is Visually Impaired, Katherine M E Stewart

Journal of Science Education for Students with Disabilities

This paper summarizes my experience with teaching a first-year, General Chemistry course to a visually impaired student. This includes accommodations and modifications for both the lecture material and the laboratory. Included are also examples of formats and syntax for txt-based quizzes, tests, and laboratory reports, as well as other general accommodations for both the student and the service dog.

Application Of Bradford’S Law Of Scattering On Research Publication In Astronomy & Astrophysics Of India, Satish Kumar, Senthilkumar R. Dec 2018

Application Of Bradford’S Law Of Scattering On Research Publication In Astronomy & Astrophysics Of India, Satish Kumar, Senthilkumar R.

Library Philosophy and Practice (e-journal)

The present study is focused on examining the application of Bradford’s law of scattering on research articles published in the field of Astronomy & Astrophysics by Indian scientist during 1988-2017. The bibliographic data was retrieved from Web of Science (WoS) bibliographic data base for different period of time. Total 18,877 journal’s article have been published by Indian scientist in the field of Astronomy & Astrophysics during 1988-2017 which was further retrieved and analyzed separately for different blocks of 10 years as well as for 30 years consolidated too. The core journal of the field was identified. The Bradford law ...

Elaia 2018, Stephen Case Dec 2018

Elaia 2018, Stephen Case

ELAIA

Over the years, the Program has continued to grow and flourish, and the depth of its research continues to increase. This inaugural journal represents the fruits of that development, containing capstone research projects from the 2018 Honors Program senior class and their faculty mentors. The Table of Contents is diverse, and in that way it is a crystal clear reflection of our program’s community of scholars.

I, along with the members of the Honors Council, am gratified by the work of each student and faculty mentor printed within these pages. Congratulations, everyone!

- Stephen Lowe, Honors Program Director

A Proficient Two-Stage Stratified Randomized Response Strategy, Tanveer A. Tarray, Housila P. Singh Dec 2018

A Proficient Two-Stage Stratified Randomized Response Strategy, Tanveer A. Tarray, Housila P. Singh

Journal of Modern Applied Statistical Methods

A stratified randomized response model based on R. Singh, Singh, Mangat, and Tracy (1995) improved two-stage randomized response strategy is proposed. It has an optimal allocation and large gain in precision. Conditions are obtained under which the proposed model is more efficient than R. Singh et al. (1995) and H. P. Singh and Tarray (2015) models. Numerical illustrations are also given in support of the present study.

Dec 2018

Discontinuity Propagation In Delay Differential-Algebraic Equations, Benjamin Unger

Electronic Journal of Linear Algebra

The propagation of primary discontinuities in initial value problems for linear delay differential-algebraic equations (DDAEs) is discussed. Based on the (quasi-) Weierstra{\ss} form for regular matrix pencils, a complete characterization of the different propagation types is given and algebraic criteria in terms of the matrices are developed. The analysis, which is based on the method of steps, takes into account all possible inhomogeneities and history functions and thus serves as a worst-case scenario. Moreover, it reveals possible hidden delays in the DDAE and allows to study exponential stability of the DDAE based on the spectral abscissa. The new classification ...

Dec 2018

Asymptotic Results On The Condition Number Of Fd Matrices Approximating Semi-Elliptic Pdes, Paris Vassalos

Electronic Journal of Linear Algebra

This work studies the asymptotic behavior of the spectral condition number of the matrices $A_{nn}$ arising from the discretization of semi-elliptic partial differential equations of the form \bdm -\left( a(x,y)u_{xx}+b(x,y)u_{yy}\right)=f(x,y), \edm on the square $\Omega=(0,1)^2,$ with Dirichlet boundary conditions, where the smooth enough variable coefficients $a(x,y), b(x,y)$ are nonnegative functions on $\overline{\Omega}$ with zeros. In the case of coefficient functions with a single and common zero, it is discovered that apart from the minimum order of the zero ...

Late Quaternary Evolution And Stratigraphic Framework Influence On Coastal Systems Along The North-Central Gulf Of Mexico, Usa, Robert Hollis

Master's Theses

Coastal systems in the Gulf of Mexico are threatened to reduced sediment supply, storm impacts and relative sea level rise (RSLR). The geologic record can provide insights of geomorphic threshold crossings (formation, progradation, transgression, destruction) to these forcing mechanisms to predict future barrier evolution to climate change. The stratigraphic framework and antecedent topography directly influence coastal evolution over geologic timescales. This study synthesizes ~2100km of geophysical data, 700+ sediment cores, and 63 radiocarbon dates to regionally map two sequence boundaries, multiple ravinement surfaces and fourteen depositional facies. One marine isotope stage (MIS) 6 valley’s fill provided up to 300 ...

Nonlinear Optical Characterization Of Solids, Alex Farnsworth Dec 2018

Nonlinear Optical Characterization Of Solids, Alex Farnsworth

Vibrational Sum Frequency Generation (VSFG) and the similar Second Harmonic Generation (SHG) are both classified as nonlinear optical phenomena, with the hallmark trait being that the input and output frequencies are different. Both of these systems are remarkable tools due to their surface specific nature. Still, there is much that is not known about the response from these systems, especially the nonresonant SFG response. We have worked to better understand SFG signal, specifically the nonresonant temporal profile. We have also collected results that call into question some underlying assumptions about time-based suppression methods when working with single crystal substrates.

As ...

Dynamical Electron Vortices In Attosecond Double Photoionization Of H2, Jean Marcel Ngoko Djiokap, A. V. Meremianin, N. L. Manakov, L. B. Madsen, S. X. Hu, Anthony F. Starace Dec 2018

Dynamical Electron Vortices In Attosecond Double Photoionization Of H2, Jean Marcel Ngoko Djiokap, A. V. Meremianin, N. L. Manakov, L. B. Madsen, S. X. Hu, Anthony F. Starace

Anthony F. Starace Publications

We study electron momentum vortices in single-photon double ionization of H2 by time-delayed, counterrotating, elliptically polarized attosecond pulses propagating along either parallel or perpendicular to the molecular axis R. For kˆ | R, kinematical vortices occur similar to those found for He. For R, we find dynamical vortex structures originating from an ellipticity-dependent interplay of 1+u and 1+u continuum amplitudes. We propose a complete experiment to determine the magnitudes and relative phase of these amplitudes by varying pulse ellipticities and time delays.

Dec 2018

Holocene Formation And Evolution Of Horn Island, Mississippi, Usa, Nina Gal

Master's Theses

Horn Island, one of the most stable barriers along the Mississippi-Alabama chain, provides critical habitat, helps regulate estuarine conditions in the Mississippi Sound, and reduces wave energy and storm surge for the mainland. This study integrates 2,200 km of high-resolution geophysics, 35 sediment cores, and 15 radiocarbon ages to better understand the formation and evolution of the island in response to sea-level rise, storms, and antecedent geology. The Biloxi and Pascagoula incised valleys converge at Horn Island and have played a profound role in the evolution of the system. Within the incised valleys, numerous shallow paleochannels between 4 and ...

Regularity Radius: Properties, Approximation And A Not A Priori Exponential Algorithm, David Hartman, Milan Hladik Dec 2018

Regularity Radius: Properties, Approximation And A Not A Priori Exponential Algorithm, David Hartman, Milan Hladik

Electronic Journal of Linear Algebra

The radius of regularity, sometimes spelled as the radius of nonsingularity, is a measure providing the distance of a given matrix to the nearest singular one. Despite its possible application strength this measure is still far from being handled in an efficient way also due to findings of Poljak and Rohn providing proof that checking this property is NP-hard for a general matrix. There are basically two approaches to handle this situation. Firstly, approximation algorithms are applied and secondly, tighter bounds for radius of regularity are considered. Improvements of both approaches have been recently shown by Hartman and Hlad\'{i ...

Coupling Between Land–Ocean–Atmosphere And Pronounced Changes In Atmospheric/Meteorological Parameters Associated With The Hudhud Cyclone Of October 2014, Akshansa Chauhan, Rajesh Kumar, Ramesh P. Singh Dec 2018

Coupling Between Land–Ocean–Atmosphere And Pronounced Changes In Atmospheric/Meteorological Parameters Associated With The Hudhud Cyclone Of October 2014, Akshansa Chauhan, Rajesh Kumar, Ramesh P. Singh

Mathematics, Physics, and Computer Science Faculty Articles and Research

India is vulnerable to all kinds of natural hazards associated with land, ocean, biosphere, atmosphere, and snow/glaciers. These natural hazards impact large areas and the population living in the affected regions. India is surrounded by ocean on three sides and is vulnerable to cyclonic activities. Every year cyclones hit the east and west coasts of India, affecting the population living along the coasts and infrastructure and inland areas. The extent of the affected inland areas depends on the intensity of the cyclone. On 12 October 2014, a strong cyclone “Hudhud” hit the east coast of India that caused a ...

Land Use And Land Cover Changes, And Environment And Risk Evaluation Of Dujiangyan City (Sw China) Using Remote Sensing And Gis Techniques, Biswajit Nath, Zheng Niu, Ramesh P. Singh Dec 2018

Land Use And Land Cover Changes, And Environment And Risk Evaluation Of Dujiangyan City (Sw China) Using Remote Sensing And Gis Techniques, Biswajit Nath, Zheng Niu, Ramesh P. Singh

Mathematics, Physics, and Computer Science Faculty Articles and Research

Understanding of the Land Use and Land Cover (LULC) change, its transitions and Landscape risk (LR) evaluation in earthquake-affected areas is important for planning and urban sustainability. In the present study, we have considered Dujiangyan City and its Environs (DCEN), a seismic-prone area close to the 2008 Wenchuan earthquake (8.0 Mw) during 2007–2018. Five different multi-temporal data sets for the years 2007, 2008, 2010, 2015, and 2018 were considered for LULC mapping, followed by the maximum likelihood supervised classification technique. The individual LULC maps were further used in four time periods, i.e., 2007–2018, 2008–2018, 2010 ...

User Attitudes About Duo Two-Factor Authentication At Byu, Jonathan Dutson Dec 2018

User Attitudes About Duo Two-Factor Authentication At Byu, Jonathan Dutson

Simple password-based authentication provides insufficient protection against increasingly common incidents of online identity theft and data loss. Although two-factor authentication (2FA) provides users with increased protection against attackers, users have mixed feelings about the usability of 2FA. We surveyed the students, faculty, and staff of Brigham Young University (BYU) to measure user sentiment about DUO Security, the 2FA system adopted by BYU in 2017. We find that most users consider DUO to be annoying, and about half of those surveyed expressed a preference for authentication without using a second-factor. About half of all participants reported at least one instance of ...

Subsets Of Vertices Of The Same Size And The Same Maximum Distance, Maria Axenovich, Dominik Duerrschnabel Dec 2018

Subsets Of Vertices Of The Same Size And The Same Maximum Distance, Maria Axenovich, Dominik Duerrschnabel

Theory and Applications of Graphs

For a simple connected graph $G=(V,E)$ and a subset $X$ of its vertices, let $$d^*(X) = \max\{{\rm dist}_G(x,y): x,y\in X\}$$ and let

$h^*(G)$ be the largest $k$ such that there are disjoint vertex subsets $A$ and $B$ of $G$, each of size $k$ such that $d^*(A) = d^*(B).$

Let $h^*(n) = \min \{h^*(G): |V(G)|=n\}$. We prove that $h^*(n) = \lfloor (n+1)/3 \rfloor,$ for $n\geq 6.$ This solves the homometric set problem restricted to the largest distance exactly. In addition we compare $h^*(G)$ with ...

Tcp Server And Client: Bookstore Enquiry, Fawaz Bukhowa Dec 2018

Tcp Server And Client: Bookstore Enquiry, Fawaz Bukhowa

Student Scholar Symposium Abstracts and Posters

An application called "Bookstore Enquiry", and it is implemented in Java using TCP client-server program. It contains two programs; one program is called "Server" and another one is called "Client". In this application, the 'server' maintains information about books and for each book it stores information like 'BookId', 'BookName', 'BookEdition', 'AvailableStock', 'UnitPrice', 'Discount'. This application works in such a way that, the server runs indefinitely and waits for client requests. The Client will accept the BookId & BookName from console and send it to server. If the server finds any books that matches with sent details, then it shows "BOOK FOUND ...

Quantification Of Voc Emissions From Carbonized Refuse-Derived Fuel Using Solid-Phase Microextraction And Gas Chromatography-Mass Spectrometry, Andrzej Białowiec, Monika Micuda, Antoni Szumny, Jacek Łyczko, Jacek A. Koziel Dec 2018

Quantification Of Voc Emissions From Carbonized Refuse-Derived Fuel Using Solid-Phase Microextraction And Gas Chromatography-Mass Spectrometry, Andrzej Białowiec, Monika Micuda, Antoni Szumny, Jacek Łyczko, Jacek A. Koziel

Agricultural and Biosystems Engineering Publications

In this work, for the first time, the volatile organic compound (VOC) emissions from carbonized refuse-derived fuel (CRDF) were quantified on a laboratory scale. The analyzed CRDF was generated from the torrefaction of municipal waste. Headspace solid-phase microextraction (SPME) and gas chromatography-mass spectrometry (GC-MS) was used to identify 84 VOCs, including many that are toxic, e.g., derivatives of benzene or toluene. The highest emissions were measured for nonanal, octanal, and heptanal. The top 10 most emitted VOCs contributed to almost 65% of the total emissions. The VOC mixture emitted from torrefied CRDF differed from that emitted by other types ...