Physical Sciences and Mathematics Commons^™

Probing The Inner Structure Of Active Galactic Nuclei Through Reverberation Mapping, Viraja Chandrashekhar Khatu

Electronic Thesis and Dissertation Repository

In the centres of massive galaxies, active galactic nuclei (AGN) are supermassive black holes, surrounded by an accretion disk of ionized gas, that release tremendous energy in the form of electromagnetic radiation. Because AGN are unresolved through telescopes, we employ reverberation mapping (RM) to study their structure. RM capitalizes on the fact that AGN are variable – the continuum emission from the accretion disk varies, and surrounding gas (in the broad-line region, BLR) responds to those variations with a positive time lag. RM translates the measured time lag into a size of the BLR. Combined with gas velocities (measured from …

Compound Sums, Their Distributions, And Actuarial Pricing, Ang Li

Electronic Thesis and Dissertation Repository

Compound risk models are widely used in insurance companies to mathematically describe their aggregate amount of losses during certain time period. However, evaluation of the distribution of compound random variables and the computation of the relevant risk measures are non-trivial. Therefore, the main purpose of this thesis is to study the bounds and simulation methods for both univariate and multivariate compound distributions. The premium setting principles related to dependent multivariate compound distributions are studied. .

In the first part of this thesis, we consider the upper and lower bounds of the tail of bivariate compound distributions. Our results extend those …

Using An Analytical Approach Of The Kuramoto Model To Stimulate 3d Neural Activity Of The Stomach, Morteza Al Rabya

Undergraduate Student Research Internships Conference

No abstract provided.

Numerical Simulation Of Adaptive Metabolic Response To Anti-Angiogenic Treatment In Renal Cell Carcinoma, Saranya Varakunan

Undergraduate Student Research Internships Conference

Renal cell carcinoma, a malignant kidney cancer, is often treated using anti-angiogenic drugs to prevent the growth of blood vessels within the tumour. Although tumours initially respond to this treatment, they eventually develop resistance. This resistance is hypothesized to be caused by a switch to a symbiotic metabolism that allows cells to survive even with a low blood supply.

This project seeks to computationally model the transport of oxygen, lactate, and glucose within a tumour in order to examine how cancer metabolism adapts to changes in blood vessels.

On The Estimation Of Heston-Nandi Garch Using Returns And/Or Options: A Simulation-Based Approach, Xize Ye

Electronic Thesis and Dissertation Repository

In this thesis, the Heston-Nandi GARCH(1,1) (henceforth, HN-GARCH) option pricing model is fitted via 4 maximum likelihood-based estimation and calibration approaches using simulated returns and/or options. The purpose is to examine the benefits of the joint estimation using both returns and options over the fundamental returns-only estimation on GARCH models. From our empirical studies, with the additional option sample, we can improve the efficiency of the estimates for HN-GARCH parameters. Nonetheless, the improvements for the risk premium factor, both from empirical standard errors, and sample RMSEs, are insignificant. In addition, option prices are simulated with a pre-defined noise structure and …

Complex Event Processing As A Service In Multi-Cloud Environments, Wilson A. Higashino

Electronic Thesis and Dissertation Repository

The rise of mobile technologies and the Internet of Things, combined with advances in Web technologies, have created a new Big Data world in which the volume and velocity of data generation have achieved an unprecedented scale. As a technology created to process continuous streams of data, Complex Event Processing (CEP) has been often related to Big Data and used as a tool to obtain real-time insights. However, despite this recent surge of interest, the CEP market is still dominated by solutions that are costly and inflexible or too low-level and hard to operate.

To address these problems, this research …

Tropical Cyclone Wind Hazard Assessment For Southeast Part Of Coastal Region Of China, Sihan Li

Electronic Thesis and Dissertation Repository

Tropical cyclone (TC) or typhoon wind hazard and risk are significant for China. The return period value of the maximum typhoon wind speed is used to characterize the typhoon wind hazard and assign wind load in building design code. Since the historical surface observations of typhoon wind speed are often scarce and of short period, the typhoon wind hazard assessment is often carried out using the wind field model and TC track model. For a few major cities in the coastal region of mainland China, simple or approximated wind field models and a circular subregion method (CSM) have been used …

Using Cellular Automata And Lattice Boltzmann Methods To Model Cancer Growth: Analysis Of Combination Treatment Outcomes, Jenna L. Butler

Electronic Thesis and Dissertation Repository

In Canada it is estimated that 76,600 people will die of cancer in 2014. Cancer, a collection of over 200 diseases, has differences existing between globally, between individuals and overtime in one individual. Treatment options are similarly varied. These differences make selecting the best possible treatment for every type of cancer very challenging. In addition, with no single cure for cancer, treatments are often combined in different ways to form the best overall option. In an attempt to synthesize the properties of these diseases into a collection of common cellular changes, Hanahan and Weinberg proposed ``the hallmarks of cancer" -- …

An Approach To Artificial Society Generation For Video Games, Bryan Sarlo

Electronic Thesis and Dissertation Repository

Since their inception in the 1940s, video games have always had a need for non-player characters (NPCs) driven by some form of artificial intelligence (AI). More recently, researchers and developers have attempted to create believable, or human-like, agents by modeling them after humans by borrowing concepts from the social sciences. This thesis explores an approach to generating a society of such believable agents with human-like attributes and social connections. This approach allows agents to form various kinds of relationships with other agents in the society, and even provides an introductory form of shared or influenced attributes based on their spouse …

Analysis Of Re-Advanceable Mortgages, Almas Naseem

Electronic Thesis and Dissertation Repository

According to Canadian tax law the interest payments on loans used for investment purposes are tax deductible while interest on personal mortgage loans is not. One way of transforming from non-tax deductible to tax deductible interest expenses is to borrow against home equity to make investments. This can be achieved through a re-advanceable mortgage and has been promoted by personal financial planners as a way of significantly decreasing the time required to pay off a mortgage and the associated total interest cost. However, the notion of risk associated with the investment holdings is not emphasized. Using simulation we study the …

Migration Behaviour Of Discontinuous Buffers In Capillary Electrophoresis During Protein Enrichment, Ting Li

Electronic Thesis and Dissertation Repository

To enrich protein at sub-microliter sample volumes, our group has developed a discontinuous buffer system which consists of an acid and a base inside a capillary. Upon voltage application, the protein moves towards and stacks at the pH junction. Prior to this work, we only focused on the protein enrichment and have not investigated the migration behaviour of various ions in this system. However, it is important to understand the mechanism of the migration of these ions, because the pH junction formation and further the protein enrichment are based on it. In this work, the ion migration patterns at the …