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Full-Text Articles in Physical Sciences and Mathematics
Characterization Of Glycated Proteins By 13C Nmr Spectroscopy, Carolyn I. Neglia, Helga J. Cohen, Albert R. Garber, Suzanne R. Thorpe, John W. Baynes
Characterization Of Glycated Proteins By 13C Nmr Spectroscopy, Carolyn I. Neglia, Helga J. Cohen, Albert R. Garber, Suzanne R. Thorpe, John W. Baynes
Faculty Publications
13C NMR spectroscopy has been used to characterize Amadori (ketoamine) adducts formed by reaction of [2-13C]glucose with free amino groups of protein. The spectra of glycated proteins were acquired in phosphate buffer at pH 7.4 and were interpreted by reference to the spectra of model compounds, N alpha-formyl-N epsilon-fructose-lysine and glycated poly-L-lysine (GlcPLL). The anomeric carbon region of the spectrum (approximately 90-105 ppm) of glycated cytochrome c was superimposable on that of N alpha-formyl-N epsilon-fructose-lysine, and contained three peaks characteristic of the alpha- and beta-furanose and beta-pyranose anomers of Amadori adducts to peripheral lysine residues on protein (pK alpha approximately …
A Continuous Dilution Calibration Technique For Flame Atomic-Absorption Spectrophotometry, Julian Tyson, J. M.H. Appleton
A Continuous Dilution Calibration Technique For Flame Atomic-Absorption Spectrophotometry, Julian Tyson, J. M.H. Appleton
Chemistry Department Faculty Publication Series
Calibration in atomic-absorption spectrometry is achieved by means of a concentration-gradient chamber using a single concentrated standard solution. Calibration is rapid and extends over the entire working concentration range of the analyte, irrespective of the shape of the conventionally obtained calibration curve. No curve-fitting approximations are involved. With well-designed apparatus, deviations are less than 1%.
Honorary Publicity Secretary's Column, Julian Tyson
Honorary Publicity Secretary's Column, Julian Tyson
Chemistry Department Faculty Publication Series
No abstract provided.
A Three Part Research Report: The Synthesis Of Potential Insecticides, N-(4-Heteroaryloxybenzoyl)-N'-(2,4-Dichlorobenzoyl) Hydrazines: A Reinvestigation Of Hexamethylphosphoramide With Ketoximes; Regioselective Fluoralkoxylation And Polyfluoroalkoxylation Of Activated Dihalobenzenes And Dihaloheterocycles, Gary A. Decrescenzo
Retrospective Theses and Dissertations
This report discusses research in three areas of organic synthesis: The synthesis of potential insecticides; the reinvestigation of the reaction of hexamethylphosphoramide with ketoximes; and the regioselective fluoroalkoxylation and polyfluoroalkoxylation of activated dihalobenzenes and dihaloheterocycles. In Part I, a series of N-(4-heteroaryloxybenzoyl)-N'-(2, 3-dichlorobenzoyl) hydrazines are synthesized, and attempts at cyclic dehydration to the corresponding 2, 5-disubstituted-1, 3, 4-oxadiazoles are discussed. In Part II, the synthesis of N, N-dimethyl-N'-aryl amidines by the reaction of aryl alkyl and diaryl ketoximes with HMPA is discussed. In Part III, a series of activated dihalobenzenes and dihaloheterocycles are reacted with sodium trifluoroethoxide to study the …
Copper And Barium As Dietary Discriminants: The Effects Of Diagenesis, J B. Lambert, S V. Simpson, Carole B. Szpunar, J E. Buikstra
Copper And Barium As Dietary Discriminants: The Effects Of Diagenesis, J B. Lambert, S V. Simpson, Carole B. Szpunar, J E. Buikstra
Chemistry: Faculty Publications and Other Works
In skeletons excavated from Woodland sites, copper and barium levels are found to have been contaminated by influx from the soil environment. Electron microprobe scans for both elements show build-up along the outer surface of femur cross sections. Elemental levels for Cu and Ba are lower in the femur or fibula than in the more porous rib. The distribution of Cu in the immediately surrounding soil is highly anisotropic. These observations indicate that Cu and Ba should not be used for dietary inferences about ancient populations without independent evidence that diagenesis is not important.