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Physical Sciences and Mathematics Commons™
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- Atmospheric aerosols (1)
- Cytochrome P450; coumarins; docking; quantitative structure-activity relationship (QSAR); hologram quantitative structure-activity relationship (HQSAR); comparative molecular field analysis (CoMFA); comparative molecular similarity index analysis (CoMSIA); molecular modeling; active site; competitive inhibition; time-dependent inhibition (1)
- Flashes TGFs (1)
- Geology (1)
- Human endogenous retroviruses (HERVs) (1)
Articles 1 - 4 of 4
Full-Text Articles in Physical Sciences and Mathematics
Gamma Ray Flashes Produced By Lightning Observed At Ground Level By Tetra-Ii, D. J. Pleshinger, S. T. Alnussirat, J. Arias, S. Bai, Y. Banadaki, M. L. Cherry, Anderson Sunda-Meya
Gamma Ray Flashes Produced By Lightning Observed At Ground Level By Tetra-Ii, D. J. Pleshinger, S. T. Alnussirat, J. Arias, S. Bai, Y. Banadaki, M. L. Cherry, Anderson Sunda-Meya
Faculty and Staff Publications
In its first 2 years of operation, the ground-based Terrestrial gamma ray flash and Energetic Thunderstorm Rooftop Array (TETRA)-II array of gamma ray detectors has recorded 22 bursts of gamma rays of millisecond-scale duration associated with lightning. In this study, we present the TETRA-II observations detected at the three TETRA-II ground-level sites in Louisiana, Puerto Rico, and Panama together with the simultaneous radio frequency signals from the lightning data sets VAISALA Global Lightning Dataset, VAISALA National Lightning Detection Network, Earth Networks Total Lightning Network, andWorld Wide Lightning Location Network. The relative timing between the gamma ray events and the lightning …
An Overview Of Handheld Sun Photometer Measurements Of Atmospheric Aerosols In New Orleans, Louisiana: A Case Study Of The Xavier University Study Site., M. Bradley, B. Sevalia, M. Gasseller
An Overview Of Handheld Sun Photometer Measurements Of Atmospheric Aerosols In New Orleans, Louisiana: A Case Study Of The Xavier University Study Site., M. Bradley, B. Sevalia, M. Gasseller
Faculty and Staff Publications
Aerosol optical depth (AOT) was measured at Xavier University of Louisiana (XULA, 29.96ᵒ N, 90.11° W and 3m above sea level) using a GLOBE handheld sun photometer. The measurements were done at two different wavelengths, 505nm and 625nm. The measured values were used to extrapolate the AOT values for wavelengths 667nm, 551nm, 532nm and 490nm at the XULA site. The measured and calculated AOT values were then compared with values from the nearest AERONET station at Wave CIS site 6 (AERONET, 28.87ᵒ N, 90.48° W and 33m above sea level), which is 60 miles south of XULA. In this study …
Coumarins And P450s, Studies Reported To-Date, Maryam Foroozesh, Jayalakshmi Sridhar, Navneet Goyal, Jiawang Liu
Coumarins And P450s, Studies Reported To-Date, Maryam Foroozesh, Jayalakshmi Sridhar, Navneet Goyal, Jiawang Liu
Faculty and Staff Publications
Cytochrome P450 enzymes (CYPs) are important phase I enzymes involved in themetabolism of endogenous and xenobiotic compounds mainly through mono-oxygenation reactions into more polar and easier to excrete species. In addition to their role in detoxification, they play important roles in the biosynthesis of endogenous compounds and the bioactivation of xenobiotics. Coumarins, phytochemicals abundant in food and commonly used in fragrances and cosmetics, have been shown to interact with P450 enzymes as substrates and/or inhibitors. In this review, these interactions and their significance in pharmacology and toxicology are discussed in detail.
Transactivation Of Human Endogenous Retroviruses By Tumor Viruses And Their Functions In Virus-Associated Malignancies., Jungang Chen, Maryam Foroozesh, Zhiqiang Qin
Transactivation Of Human Endogenous Retroviruses By Tumor Viruses And Their Functions In Virus-Associated Malignancies., Jungang Chen, Maryam Foroozesh, Zhiqiang Qin
Faculty and Staff Publications
Human endogenous retroviruses (HERVs), viral-associated sequences, are normal components of the human genome and account for 8–9% of our genome. These original provirus sequences can be transactivated to produce functional products. Several reactivated HERVs have been implicated in cancers and autoimmune diseases. An emerging body of literature supports a potential role of reactivated HERVs in viral diseases, in particular viral-associated neoplasms. Demystifying studies on the mechanism(s) of HERV reactivation could provide a new framework for the development of treatment and prevention strategies targeting virus-associated tumors. Although available data suggest that coinfection by other viruses, such as Kaposi’s Sarcoma-associated herpesvirus (KSHV) …