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2016

University of Kentucky

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Articles 1 - 30 of 272

Full-Text Articles in Physical Sciences and Mathematics

Sdss-Iv Manga: Spatially Resolved Star Formation Histories In Galaxies As A Function Of Galaxy Mass And Type, D. Goddard, D. Thomas, C. Maraston, K. Westfall, J. Etherington, R. Riffel, M. D. Mallmann, Z. Zheng, M. Argudo-Fernández, J. Lian, M. Bershady, K. Bundy, N. Drory, D. Law, Renbin Yan, D. Wake, A. Weijmans, D. Bizyaev, J. Brownstein, R. R. Lane, R. Maiolino, K. Masters, M. Merrifield, C. Nitschelm, K. Pan, A. Roman-Lopes, T. Storchi-Bergmann, D. P. Schneider Dec 2016

Sdss-Iv Manga: Spatially Resolved Star Formation Histories In Galaxies As A Function Of Galaxy Mass And Type, D. Goddard, D. Thomas, C. Maraston, K. Westfall, J. Etherington, R. Riffel, M. D. Mallmann, Z. Zheng, M. Argudo-Fernández, J. Lian, M. Bershady, K. Bundy, N. Drory, D. Law, Renbin Yan, D. Wake, A. Weijmans, D. Bizyaev, J. Brownstein, R. R. Lane, R. Maiolino, K. Masters, M. Merrifield, C. Nitschelm, K. Pan, A. Roman-Lopes, T. Storchi-Bergmann, D. P. Schneider

Physics and Astronomy Faculty Publications

We study the internal gradients of stellar population properties within 1.5 Re for a representative sample of 721 galaxies, with stellar masses ranging between 109 M and 1011.5 M from the SDSS-IV MaNGA Integral-Field-Unit survey. Through the use of our full spectral fitting code firefly, we derive light- and mass-weighted stellar population properties and their radial gradients, as well as full star formation and metal enrichment histories. We also quantify the impact that different stellar population models and full spectral fitting routines have on the derived stellar population properties and the radial gradient measurements. In …


Myofilament Calcium Sensitivity: Consequences Of The Effective Concentration Of Troponin I, Jalal K. Siddiqui, Svetlana B. Tikunova, Shane D. Walton, Bin Liu, Meredith Meyer, Pieter P. De Tombe, Nathan Neilson, Peter M. Kekenes-Huskey, Hussam E. Salhi, Paul M.L. Janssen, Brandon J. Biesiadecki, Jonathan P. Davis Dec 2016

Myofilament Calcium Sensitivity: Consequences Of The Effective Concentration Of Troponin I, Jalal K. Siddiqui, Svetlana B. Tikunova, Shane D. Walton, Bin Liu, Meredith Meyer, Pieter P. De Tombe, Nathan Neilson, Peter M. Kekenes-Huskey, Hussam E. Salhi, Paul M.L. Janssen, Brandon J. Biesiadecki, Jonathan P. Davis

Chemistry Faculty Publications

Control of calcium binding to and dissociation from cardiac troponin C (TnC) is essential to healthy cardiac muscle contraction/relaxation. There are numerous aberrant post-translational modifications and mutations within a plethora of contractile, and even non-contractile, proteins that appear to imbalance this delicate relationship. The direction and extent of the resulting change in calcium sensitivity is thought to drive the heart toward one type of disease or another. There are a number of molecular mechanisms that may be responsible for the altered calcium binding properties of TnC, potentially the most significant being the ability of the regulatory domain of TnC to …


Sdss-Iv Manga: The Impact Of Diffuse Ionized Gas On Emission-Line Ratios, Interpretation Of Diagnostic Diagrams And Gas Metallicity Measurements, Kai Zhang, Renbin Yan, Kevin Bundy, Matthew Bershady, L. Matthew Haffner, René Walterbos, Roberto Maiolino, Christy Tremonti, Daniel Thomas, Niv Drory, Amy Jones, Francesco Belfiore, Sebastian F. Sánchez, Aleksandar M. Diamond-Stanic, Dmitry Bizyaev, Christian Nitschelm, Brett Andrews, Jon Brinkmann, Joel R. Brownstein, Edmond Cheung, Cheng Li, David R. Law, Alexandre Roman Lopes, Daniel Oravetz, Kaike Pan, Thaisa Storchi Bergmann, Audrey Simmons Dec 2016

Sdss-Iv Manga: The Impact Of Diffuse Ionized Gas On Emission-Line Ratios, Interpretation Of Diagnostic Diagrams And Gas Metallicity Measurements, Kai Zhang, Renbin Yan, Kevin Bundy, Matthew Bershady, L. Matthew Haffner, René Walterbos, Roberto Maiolino, Christy Tremonti, Daniel Thomas, Niv Drory, Amy Jones, Francesco Belfiore, Sebastian F. Sánchez, Aleksandar M. Diamond-Stanic, Dmitry Bizyaev, Christian Nitschelm, Brett Andrews, Jon Brinkmann, Joel R. Brownstein, Edmond Cheung, Cheng Li, David R. Law, Alexandre Roman Lopes, Daniel Oravetz, Kaike Pan, Thaisa Storchi Bergmann, Audrey Simmons

Physics and Astronomy Faculty Publications

Diffuse ionized gas (DIG) is prevalent in star-forming galaxies. Using a sample of 365 nearly face-on star-forming galaxies observed by Mapping Nearby Galaxies at APO, we demonstrate how DIG in star-forming galaxies impacts the measurements of emission-line ratios, hence the interpretation of diagnostic diagrams and gas-phase metallicity measurements. At fixed metallicity, DIG-dominated low Σ regions display enhanced [S II]/Hα, [N II]/Hα, [O II]/Hβ and [O I]/Hα. The gradients in these line ratios are determined by metallicity gradients and Σ. In line ratio diagnostic diagrams, contamination by DIG moves H II …


Distributed All-Ip Mobility Management Architecture Supported By The Ndn Overlay, Zhiwei Yan, Guanggang Geng, Sherali Zeadally, Yong-Jin Park Dec 2016

Distributed All-Ip Mobility Management Architecture Supported By The Ndn Overlay, Zhiwei Yan, Guanggang Geng, Sherali Zeadally, Yong-Jin Park

Information Science Faculty Publications

Two of the most promising candidate solutions for realizing the next-generation all-IP mobile networks are Mobile IPv6 (MIPv6), which is the host-based and global mobility supporting protocol, and Proxy MIPv6 (PMIPv6), which is the network-based and localized mobility supporting protocol. However, the unprecedented growth of mobile Internet traffic has resulted in the development of distributed mobility management (DMM) architecture by the Internet engineering task force DMM working group. The extension of the basic MIPv6 and PMIPv6 to support their distributed and scalable deployment in the future is one of the major goals of the DMM working group. We propose an …


Sdss-Iv Manga – The Spatially Resolved Transition From Star Formation To Quiescence, Francesco Belfiore, Roberto Maiolino, Claudia Maraston, Eric Emsellem, Matthew A. Bershady, Karen L. Masters, Dmitry Bizyaev, Médéric Boquien, Joel R. Brownstein, Kevin Bundy, Aleksandar M. Diamond-Stanic, Niv Drory, Timothy M. Heckman, David R. Law, Olena Malanushenko, Audrey Oravetz, Kaike Pan, Alexandre Roman-Lopes, Daniel Thomas, Anne-Marie Weijmans, Kyle B. Westfall, Renbin Yan Dec 2016

Sdss-Iv Manga – The Spatially Resolved Transition From Star Formation To Quiescence, Francesco Belfiore, Roberto Maiolino, Claudia Maraston, Eric Emsellem, Matthew A. Bershady, Karen L. Masters, Dmitry Bizyaev, Médéric Boquien, Joel R. Brownstein, Kevin Bundy, Aleksandar M. Diamond-Stanic, Niv Drory, Timothy M. Heckman, David R. Law, Olena Malanushenko, Audrey Oravetz, Kaike Pan, Alexandre Roman-Lopes, Daniel Thomas, Anne-Marie Weijmans, Kyle B. Westfall, Renbin Yan

Physics and Astronomy Faculty Publications

Using spatially resolved spectroscopy from SDSS-IV MaNGA we have demonstrated that low ionization emission-line regions (LIERs) in local galaxies result from photoionization by hot evolved stars, not active galactic nuclei, hence tracing galactic region hosting old stellar population where, despite the presence of ionized gas, star formation is no longer occurring. LIERs are ubiquitous in both quiescent galaxies and in the central regions of galaxies where star formation takes place at larger radii. We refer to these two classes of galaxies as extended LIER (eLIER) and central LIER (cLIER) galaxies, respectively. cLIERs are late-type galaxies primarily spread across the green …


Very Rapid Onset Cannabis Dependence Risk In Relation To Co-Occurring Use Of Other Psychoactive Drugs, Olga A. Vsevolozhskaya, Fernando A. Wagner, James C. Anthony Dec 2016

Very Rapid Onset Cannabis Dependence Risk In Relation To Co-Occurring Use Of Other Psychoactive Drugs, Olga A. Vsevolozhskaya, Fernando A. Wagner, James C. Anthony

Biostatistics Presentations

Background: Epidemiological estimates for lifetime cumulative incidence indicate that for every 9-11 who start using cannabis, one becomes a case of the cannabis dependence syndrome (CDS) – i.e., roughly 9%-11%. More recent estimates clarify that CDS risk might be much lower among ’cannabis only’ users, due in part to the fact that many ’cannabis only’ users try the drug a few times and never again. We turned to Hill functional analysis in order to study CDS probability soon after 1st cannabis use, estimated across strata defined by the number of recent days of cannabis use, with an acknowledgment that a …


Self-Reported Sleep Apnea And Dementia Risk: Findings From The Prevention Of Alzheimer's Disease With Vitamin E And Selenium Trial, Xiuhua Ding, Richard J. Kryscio, Joshua Turner, Gregory A. Jicha, Gregory E. Cooper, Allison M. Caban-Holt, Frederick A. Schmitt, Erin L. Abner Dec 2016

Self-Reported Sleep Apnea And Dementia Risk: Findings From The Prevention Of Alzheimer's Disease With Vitamin E And Selenium Trial, Xiuhua Ding, Richard J. Kryscio, Joshua Turner, Gregory A. Jicha, Gregory E. Cooper, Allison M. Caban-Holt, Frederick A. Schmitt, Erin L. Abner

Sanders-Brown Center on Aging Faculty Publications

OBJECTIVES: To investigate the association between baseline sleep apnea and risk of incident dementia in the Prevention of Alzheimer's Disease with Vitamin E and Selenium (PREADViSE) study and to explore whether the association depends on apolipoprotein E (APOE) ɛ4 allele status.

DESIGN: Secondary analysis based on data collected during PREADViSE.

SETTING: Participants were assessed at 128 local clinical study sites during the clinical trial phase and later were followed by telephone from a centralized location.

PARTICIPANTS: Men enrolled in PREADViSE (without dementia or other active neurological conditions that affect cognition such as major psychiatric disorders, including depression; N = …


Inter-Relationships Linking Probability Of Becoming A Case Of Nicotine Dependence With Frequency Of Tobacco Cigarette Smoking, Olga A. Vsevolozhskaya, James C. Anthony Dec 2016

Inter-Relationships Linking Probability Of Becoming A Case Of Nicotine Dependence With Frequency Of Tobacco Cigarette Smoking, Olga A. Vsevolozhskaya, James C. Anthony

Biostatistics Faculty Publications

INTRODUCTION: Once smoking starts, some tobacco cigarette smokers (TCS) can make very rapid transitions into tobacco dependence syndromes (TCD). With adjustment for smoking frequency, we posit female excess risk for this rapid-onset TCD. In a novel application of functional analysis for tobacco research, we estimate four Hill function parameters and plot TCD risk against a gradient of smoking frequency, as observed quite soon after smoking onset.

METHODS: In aggregate, the National Surveys of Drug Use and Health, 2004-2013, identified 1546 newly incident TCS in cross-sectional research, each with standardized TCD assessment.

RESULTS: Hill function estimates contradict our apparently over-simplistic hypothesis. …


Genomics And Csf Analyses Implicate Thyroid Hormone In Hippocampal Sclerosis Of Aging, Peter T. Nelson, Yuriko Katsumata, Kwangsik Nho, Sergey C. Artiushin, Gregory A. Jicha, Wang-Xia Wang, Erin L. Abner, Andrew J. Saykin, Walter A. Kukull, Alzheimer’S Disease Neuroimaging Initiative (Adni), David W. Fardo Dec 2016

Genomics And Csf Analyses Implicate Thyroid Hormone In Hippocampal Sclerosis Of Aging, Peter T. Nelson, Yuriko Katsumata, Kwangsik Nho, Sergey C. Artiushin, Gregory A. Jicha, Wang-Xia Wang, Erin L. Abner, Andrew J. Saykin, Walter A. Kukull, Alzheimer’S Disease Neuroimaging Initiative (Adni), David W. Fardo

Sanders-Brown Center on Aging Faculty Publications

We report evidence of a novel pathogenetic mechanism in which thyroid hormone dysregulation contributes to dementia in elderly persons. Two single nucleotide polymorphisms (SNPs) on chromosome 12p12 were the initial foci of our study: rs704180 and rs73069071. These SNPs were identified by separate research groups as risk alleles for non-Alzheimer’s neurodegeneration. We found that the rs73069071 risk genotype was associated with hippocampal sclerosis (HS) pathology among people with the rs704180 risk genotype (National Alzheimer’s Coordinating Center/Alzheimer’s Disease Genetic Consortium data; n = 2113, including 241 autopsy-confirmed HS cases). Furthermore, both rs704180 and rs73069071 risk genotypes were associated with widespread brain …


Sdss-Iv Manga: A Serendipitous Observation Of A Potential Gas Accretion Event, Edmond Cheung, David V. Stark, Song Huang, Kate H. R. Rubin, Lihwai Lin, Christy Tremonti, Kai Zhang, Renbin Yan, Dmitry Bizyaev, Médéric Boquien Nov 2016

Sdss-Iv Manga: A Serendipitous Observation Of A Potential Gas Accretion Event, Edmond Cheung, David V. Stark, Song Huang, Kate H. R. Rubin, Lihwai Lin, Christy Tremonti, Kai Zhang, Renbin Yan, Dmitry Bizyaev, Médéric Boquien

Physics and Astronomy Faculty Publications

The nature of warm, ionized gas outside of galaxies may illuminate several key galaxy evolutionary processes. A serendipitous observation by the MaNGA survey has revealed a large, asymmetric Hα complex with no optical counterpart that extends ≈8'' (≈6.3 kpc) beyond the effective radius of a dusty, starbursting galaxy. This Hα extension is approximately three times the effective radius of the host galaxy and displays a tail-like morphology. We analyze its gas-phase metallicities, gaseous kinematics, and emission-line ratios and discuss whether this Hα extension could be diffuse ionized gas, a gas accretion event, or something else. We find …


Sdss-Iv Manga Ifs Galaxy Survey—Survey Design, Execution, And Initial Data Quality, Renbin Yan, Kevin Bundy, David R. Law, Matthew A. Bershady, Brett Andrews, Brian Cherinka, Aleksandar M. Diamond-Stanic, Niv Drory, Nicholas Macdonald, José R. Sánchez-Gallego, Daniel Thomas, David A. Wake, Anne-Marie Weijmans, Kyle B. Westfall, Kai Zhang, Alfonso Aragón-Salamanca, Francesco Belfiore, Dmitry Bizyaev, Guillermo A. Blanc, Michael R. Blanton, Joel Brownstein, Michele Cappellari, Richard D'Souza, Eric Emsellem, Hai Fu, Patrick Gaulme, Mark T. Graham, Daniel Goddard, James E. Gunn, Paul Harding Nov 2016

Sdss-Iv Manga Ifs Galaxy Survey—Survey Design, Execution, And Initial Data Quality, Renbin Yan, Kevin Bundy, David R. Law, Matthew A. Bershady, Brett Andrews, Brian Cherinka, Aleksandar M. Diamond-Stanic, Niv Drory, Nicholas Macdonald, José R. Sánchez-Gallego, Daniel Thomas, David A. Wake, Anne-Marie Weijmans, Kyle B. Westfall, Kai Zhang, Alfonso Aragón-Salamanca, Francesco Belfiore, Dmitry Bizyaev, Guillermo A. Blanc, Michael R. Blanton, Joel Brownstein, Michele Cappellari, Richard D'Souza, Eric Emsellem, Hai Fu, Patrick Gaulme, Mark T. Graham, Daniel Goddard, James E. Gunn, Paul Harding

Physics and Astronomy Faculty Publications

The MaNGA Survey (Mapping Nearby Galaxies at Apache Point Observatory) is one of three core programs in the Sloan Digital Sky Survey IV. It is obtaining integral field spectroscopy for 10,000 nearby galaxies at a spectral resolution of R ~ 2000 from 3622 to 10354 Å. The design of the survey is driven by a set of science requirements on the precision of estimates of the following properties: star formation rate surface density, gas metallicity, stellar population age, metallicity, and abundance ratio, and their gradients; stellar and gas kinematics; and enclosed gravitational mass as a function of radius. We describe …


Adjustment And Optimization Of The Cropping Systems Under Water Constraint, Pingli An, Wei Ren, Xiliin Liu, Mengmei Song, Xuemin Li Nov 2016

Adjustment And Optimization Of The Cropping Systems Under Water Constraint, Pingli An, Wei Ren, Xiliin Liu, Mengmei Song, Xuemin Li

Plant and Soil Sciences Faculty Publications

The water constraint on agricultural production receives growing concern with the increasingly sharp contradiction between demand and supply of water resources. How to mitigate and adapt to potential water constraint is one of the key issues for ensuring food security and achieving sustainable agriculture in the context of climate change. It has been suggested that adjustment and optimization of cropping systems could be an effective measure to improve water management and ensure food security. However, a knowledge gap still exists in how to quantify potential water constraint and how to select appropriate cropping systems. Here, we proposed a concept of …


Spray Printing Of Organic Semiconducting Single Crystals, Grigorios-Panagiotis Rigas, Marcia M. Payne, John E. Anthony, Peter N. Horton, Fernando A. Castro, Maxim Shkunov Nov 2016

Spray Printing Of Organic Semiconducting Single Crystals, Grigorios-Panagiotis Rigas, Marcia M. Payne, John E. Anthony, Peter N. Horton, Fernando A. Castro, Maxim Shkunov

Chemistry Faculty Publications

Single-crystal semiconductors have been at the forefront of scientific interest for more than 70 years, serving as the backbone of electronic devices. Inorganic single crystals are typically grown from a melt using time-consuming and energy-intensive processes. Organic semiconductor single crystals, however, can be grown using solution-based methods at room temperature in air, opening up the possibility of large-scale production of inexpensive electronics targeting applications ranging from field-effect transistors and light-emitting diodes to medical X-ray detectors. Here we demonstrate a low-cost, scalable spray-printing process to fabricate high-quality organic single crystals, based on various semiconducting small molecules on virtually any substrate by …


Selective Growth Of Epitaxial Sr2Iro4 By Controlling Plume Dimensions In Pulsed Laser Deposition, Sung S. Ambrose Seo, J. Nichols, J. Hwang, Jsaminka Terzic, John H. Gruenewald, Maryam Souri, Justin K. Thompson, John G. Connell, Gang Cao Nov 2016

Selective Growth Of Epitaxial Sr2Iro4 By Controlling Plume Dimensions In Pulsed Laser Deposition, Sung S. Ambrose Seo, J. Nichols, J. Hwang, Jsaminka Terzic, John H. Gruenewald, Maryam Souri, Justin K. Thompson, John G. Connell, Gang Cao

Physics and Astronomy Faculty Publications

We report that epitaxial Sr2IrO4 thin-films can be selectively grown using pulsed laser deposition (PLD). Due to the competition between the Ruddlesden-Popper phases of strontium iridates (Srn+1IrnO3n+1), conventional PLD methods often result in mixed phases of Sr2IrO4 (n = 1), Sr3Ir2O7 (n = 2), and SrIrO3 (n = ∞). We have discovered that reduced PLD plume dimensions and slow deposition rates are the key for stabilizing pure Sr2IrO4 phase thin-films, identified by real-time in-situ monitoring of their optical spectra. …


The Quenching Timescale And Quenching Rate Of Galaxies, Jianhui Lian, Renbin Yan, Kai Zhang, Xu Kong Nov 2016

The Quenching Timescale And Quenching Rate Of Galaxies, Jianhui Lian, Renbin Yan, Kai Zhang, Xu Kong

Physics and Astronomy Faculty Publications

The average star formation rate (SFR) in galaxies has been declining since the redshift of 2. A fraction of galaxies quench and become quiescent. We constrain two key properties of the quenching process: the quenching timescale and the quenching rate among galaxies. We achieve this by analyzing the galaxy number density profile in NUV−u color space and the distribution in NUV−u versus ui color–color diagram with a simple toy-model framework. We focus on galaxies in three mass bins between 1010 and 1010.6 M . In the NUV−u versus ui color–color …


Estimating Propensity Parameters Using Google Pagerank And Genetic Algorithms, David Murrugarra, Jacob Miller, Alex N. Mueller Nov 2016

Estimating Propensity Parameters Using Google Pagerank And Genetic Algorithms, David Murrugarra, Jacob Miller, Alex N. Mueller

Mathematics Faculty Publications

Stochastic Boolean networks, or more generally, stochastic discrete networks, are an important class of computational models for molecular interaction networks. The stochasticity stems from the updating schedule. Standard updating schedules include the synchronous update, where all the nodes are updated at the same time, and the asynchronous update where a random node is updated at each time step. The former produces a deterministic dynamics while the latter a stochastic dynamics. A more general stochastic setting considers propensity parameters for updating each node. Stochastic Discrete Dynamical Systems (SDDS) are a modeling framework that considers two propensity parameters for updating each node …


Holographic Renormalization Of Einstein-Maxwell-Dilaton Theories, Bom Soo Kim Nov 2016

Holographic Renormalization Of Einstein-Maxwell-Dilaton Theories, Bom Soo Kim

Physics and Astronomy Faculty Publications

We generalize the boundary value problem with a mixed boundary condition that involves the gauge and scalar fields in the context of Einstein-Maxwell-Dilaton theories. In particular, the expectation value of the dual scalar operator can be a function of the expectation value of the current operator. The properties are prevalent in a fixed charge ensemble because the conserved charge is shared by both fields through the dilaton coupling, which is also responsible for non-Fermi liquid properties. We study the on-shell action and the stress energy tensor to note practical importances of the boundary value problem. In the presence of the …


Sign-Problem-Free Monte Carlo Simulation Of Certain Frustrated Quantum Magnets, Fabien Alet, Kedar Damle, Sumiran Pujari Nov 2016

Sign-Problem-Free Monte Carlo Simulation Of Certain Frustrated Quantum Magnets, Fabien Alet, Kedar Damle, Sumiran Pujari

Physics and Astronomy Faculty Publications

We introduce a quantum Monte Carlo (QMC) method for efficient sign-problem-free simulations of a broad class of frustrated S =1/2 antiferromagnets using the basis of spin eigenstates of clusters to avoid the severe sign problem faced by other QMC methods. We demonstrate the utility of the method in several cases with competing exchange interactions and flag important limitations as well as possible extensions of the method.


Target And Beam-Target Spin Asymmetries In Exclusive Π+ And Π Electroproduction With 1.6- To 5.7-Gev Electrons, P. E. Bosted, A. S. Biselli, S. Careccia, G. Dodge, R. Fersch, N. Guler, S. E. Kuhn, J. Pierce, Y. Prok, X. Zheng, K. P. Adhikari, D. Adikaram, Z. Akbar, M. J. Amaryan, S. Anefalos Pereira, G. Asryan, H. Avakian, R. A. Badui, J. Ball, N. A. Baltzell, M. Battaglieri, V. Batourine, I. Bedlinskiy, S. Boiarinov, W. J. Briscoe, S. Bültmann, V. D. Burkert, T. Cao, D. S. Carman, A. Celentano, Wesley P. Gohn Nov 2016

Target And Beam-Target Spin Asymmetries In Exclusive Π+ And Π− Electroproduction With 1.6- To 5.7-Gev Electrons, P. E. Bosted, A. S. Biselli, S. Careccia, G. Dodge, R. Fersch, N. Guler, S. E. Kuhn, J. Pierce, Y. Prok, X. Zheng, K. P. Adhikari, D. Adikaram, Z. Akbar, M. J. Amaryan, S. Anefalos Pereira, G. Asryan, H. Avakian, R. A. Badui, J. Ball, N. A. Baltzell, M. Battaglieri, V. Batourine, I. Bedlinskiy, S. Boiarinov, W. J. Briscoe, S. Bültmann, V. D. Burkert, T. Cao, D. S. Carman, A. Celentano, Wesley P. Gohn

Physics and Astronomy Faculty Publications

Beam-target double-spin asymmetries and target single-spin asymmetries in exclusive π+ and quasiexclusive π− electroproduction were obtained from scattering of 1.6- to 5.7-GeV longitudinally polarized electrons from longitudinally polarized protons (for π+) and deuterons (for π−) using the CEBAF Large Acceptance Spectrometer (CLAS) at Jefferson Lab. The kinematic range covered is 1.1 < W < 2.6 GeV and 0.05 < Q2 < 5 GeV2, with good angular coverage in the forward hemisphere. The asymmetry results were divided into approximately 40 000 kinematic bins for π+ from free protons and 15 000 bins for π− production from bound nucleons in the deuteron. The …


The Intermediate-Line Region In Active Galactic Nuclei, T. P. Adhikari, A. Różańska, B. Czerny, K. Hryniewicz, Gary J. Ferland Oct 2016

The Intermediate-Line Region In Active Galactic Nuclei, T. P. Adhikari, A. Różańska, B. Czerny, K. Hryniewicz, Gary J. Ferland

Physics and Astronomy Faculty Publications

We show that the recently observed suppression of the gap between the broad-line region (BLR) and the narrow-line region (NLR) in some active galactic nuclei (AGNs) can be fully explained by an increase of the gas density in the emitting region. Our model predicts the formation of the intermediate-line region (ILR) that is observed in some Seyfert galaxies by the detection of emission lines with intermediate-velocity FWHM ~ 700–1200 km s−1. These lines are believed to be originating from an ILR located somewhere between the BLR and NLR. As was previously proved, the apparent gap is assumed to …


Structure And Physical Conditions In The Huygens Region Of The Orion Nebula, C. R. O'Dell, Gary J. Ferland, M. Peimbert Oct 2016

Structure And Physical Conditions In The Huygens Region Of The Orion Nebula, C. R. O'Dell, Gary J. Ferland, M. Peimbert

Physics and Astronomy Faculty Publications

Hubble Space Telescope images, MUSE maps of emission lines, and an atlas of high velocity resolution emission-line spectra have been used to establish for the first time correlations of the electron temperature, electron density, radial velocity, turbulence, and orientation within the main ionization front of the nebula. From the study of the combined properties of multiple features, it is established that variations in the radial velocity are primarily caused by the photoevaporating ionization front being viewed at different angles. There is a progressive increase of the electron temperature and density with decreasing distance from the dominant ionizing star θ1 …


Sdss-Iv Manga: Stellar Population Gradients As A Function Of Galaxy Environment, D. Goddard, D. Thomas, C. Maraston, K. Westfall, J. Etherington, R. Riffel, M. D. Mallmann, Z. Zheng, M. Argudo-Fernández, M. A. Bershady, K. Bundy, N. Drory, D. Law, Renbin Yan, D. Wake, A. Weijmans, D. Bizyaev, J. Brownstein, R. R. Lane, R. Maiolino, K. Masters, M. Merrifield, C. Nitschelm, K. Pan, A. Roman-Lopes, T. Storchi-Bergmann Oct 2016

Sdss-Iv Manga: Stellar Population Gradients As A Function Of Galaxy Environment, D. Goddard, D. Thomas, C. Maraston, K. Westfall, J. Etherington, R. Riffel, M. D. Mallmann, Z. Zheng, M. Argudo-Fernández, M. A. Bershady, K. Bundy, N. Drory, D. Law, Renbin Yan, D. Wake, A. Weijmans, D. Bizyaev, J. Brownstein, R. R. Lane, R. Maiolino, K. Masters, M. Merrifield, C. Nitschelm, K. Pan, A. Roman-Lopes, T. Storchi-Bergmann

Physics and Astronomy Faculty Publications

We study the internal radial gradients of stellar population properties within 1.5 Re and analyse the impact of galaxy environment. We use a representative sample of 721 galaxies with masses ranging between 109 M and 1011.5 M from the SDSS-IV survey MaNGA. We split this sample by morphology into early-type and late-type galaxies. Using the full spectral fitting code firefly, we derive the light and mass-weighted stellar population properties, age and metallicity, and calculate the gradients of these properties. We use three independent methods to quantify galaxy environment, namely the Nth nearest neighbour, the …


The Growth Of The Central Region By Acquisition Of Counterrotating Gas In Star-Forming Galaxies, Yan-Mei Chen, Yong Shi, Christy A. Tremonti, Matt Bershady, Michael Merrifield, Eric Emsellem, Yi-Fei Jin, Song Huang, Hai Fu, David A. Wake, Kevin Bundy, David Stark, Lihwai Lin, Maria Argudo-Fernandez, Thaisa Storchi Bergmann, Dmitry Bizyaev, Joel Brownstein, Martin Bureau, John Chisholm, Niv Drory, Qi Guo, Lei Hao, Jian Hu, Cheng Li, Ran Li, Alexandre Roman Lopes, Kai-Ke Pan, Rogemar A Riffel, Daniel Thomas, Lan Wang, Renbin Yan Oct 2016

The Growth Of The Central Region By Acquisition Of Counterrotating Gas In Star-Forming Galaxies, Yan-Mei Chen, Yong Shi, Christy A. Tremonti, Matt Bershady, Michael Merrifield, Eric Emsellem, Yi-Fei Jin, Song Huang, Hai Fu, David A. Wake, Kevin Bundy, David Stark, Lihwai Lin, Maria Argudo-Fernandez, Thaisa Storchi Bergmann, Dmitry Bizyaev, Joel Brownstein, Martin Bureau, John Chisholm, Niv Drory, Qi Guo, Lei Hao, Jian Hu, Cheng Li, Ran Li, Alexandre Roman Lopes, Kai-Ke Pan, Rogemar A Riffel, Daniel Thomas, Lan Wang, Renbin Yan

Physics and Astronomy Faculty Publications

Galaxies grow through both internal and external processes. In about 10% of nearby red galaxies with little star formation, gas and stars are counter-rotating, demonstrating the importance of external gas acquisition in these galaxies. However, systematic studies of such phenomena in blue, star-forming galaxies are rare, leaving uncertain the role of external gas acquisition in driving evolution of blue galaxies. Here, based on new measurements with integral field spectroscopy of a large representative galaxy sample, we find an appreciable fraction of counter-rotators among blue galaxies (9 out of 489 galaxies). The central regions of blue counter-rotators show younger stellar populations …


On Combining Family- And Population- Based Sequencing Data, Yuriko Katsumata, David W. Fardo Oct 2016

On Combining Family- And Population- Based Sequencing Data, Yuriko Katsumata, David W. Fardo

Biostatistics Faculty Publications

Several statistical group-based approaches have been proposed to detect effects of variation within a gene for each of the population- and family-based designs. However, unified tests to combine gene-phenotype associations obtained from these 2 study designs are not yet well established. In this study, we investigated the efficient combination of population-based and family-based sequencing data to evaluate best practices using the Genetic Analysis Workshop 19 (GAW19) data set. Because one design employed whole genome sequencing and the other whole exome sequencing, we examined variants overlapping both data sets. We used the family-based sequence kernel association test (famSKAT) to analyze the …


Comparing Performance Of Non-Tree-Based And Tree-Based Association Mapping Methods, Katherine L. Thompson, David W. Fardo Oct 2016

Comparing Performance Of Non-Tree-Based And Tree-Based Association Mapping Methods, Katherine L. Thompson, David W. Fardo

Statistics Faculty Publications

A central goal in the biomedical and biological sciences is to link variation in quantitative traits to locations along the genome (single nucleotide polymorphisms). Sequencing technology has rapidly advanced in recent decades, along with the statistical methodology to analyze genetic data. Two classes of association mapping methods exist: those that account for the evolutionary relatedness among individuals, and those that ignore the evolutionary relationships among individuals. While the former methods more fully use implicit information in the data, the latter methods are more flexible in the types of data they can handle. This study presents a comparison of the 2 …


Causal Effect Estimation In Sequencing Studies: A Bayesian Method To Account For Confounder Adjustment Uncertainty, Chi Wang, Jinpeng Liu, David W. Fardo Oct 2016

Causal Effect Estimation In Sequencing Studies: A Bayesian Method To Account For Confounder Adjustment Uncertainty, Chi Wang, Jinpeng Liu, David W. Fardo

Biostatistics Faculty Publications

Estimating the causal effect of a single nucleotide variant (SNV) on clinical phenotypes is of interest in many genetic studies. The effect estimation may be confounded by other SNVs as a result of linkage disequilibrium as well as demographic and clinical characteristics. Because a large number of these other variables, which we call potential confounders, are collected, it is challenging to select and adjust for the variables that truly confound the causal effect. The Bayesian adjustment for confounding (BAC) method has been proposed as a general method to estimate the average causal effect in the presence of a large number …


Enhanced Metallic Properties Of Srruo3 Thin Films Via Kinetically Controlled Pulsed Laser Epitaxy, Justin K. Thompson, J. Nichols, S. Lee, S. Ryee, John H. Gruenewald, John G. Connell, Maryam Souri, J. M. Johnson, J. Hwang, M. J. Han, H. N. Lee, D. -W. Kim, Sung S. Ambrose Seo Oct 2016

Enhanced Metallic Properties Of Srruo3 Thin Films Via Kinetically Controlled Pulsed Laser Epitaxy, Justin K. Thompson, J. Nichols, S. Lee, S. Ryee, John H. Gruenewald, John G. Connell, Maryam Souri, J. M. Johnson, J. Hwang, M. J. Han, H. N. Lee, D. -W. Kim, Sung S. Ambrose Seo

Physics and Astronomy Faculty Publications

Metal electrodes are a universal element of all electronic devices. Conducting SrRuO3 (SRO) epitaxial thin films have been extensively used as electrodes in complex-oxide heterostructures due to good lattice mismatches with perovskite substrates. However, when compared to SRO single crystals, SRO thin films have shown reduced conductivity and Curie temperatures (TC), which can lead to higher Joule heating and energy loss in the devices. Here, we report that high-quality SRO thin films can be synthesized by controlling the plume dynamics and growth rate of pulsed laser epitaxy (PLE) with real-time optical spectroscopic monitoring. The SRO thin …


Fedrr: Fast, Exhaustive Detection Of Redundant Hierarchical Relations For Quality Improvement Of Large Biomedical Ontologies, Guangming Xing, Guo-Qiang Zhang, Licong Cui Oct 2016

Fedrr: Fast, Exhaustive Detection Of Redundant Hierarchical Relations For Quality Improvement Of Large Biomedical Ontologies, Guangming Xing, Guo-Qiang Zhang, Licong Cui

Institute for Biomedical Informatics Faculty Publications

Background: Redundant hierarchical relations refer to such patterns as two paths from one concept to another, one with length one (direct) and the other with length greater than one (indirect). Each redundant relation represents a possibly unintended defect that needs to be corrected in the ontology quality assurance process. Detecting and eliminating redundant relations would help improve the results of all methods relying on the relevant ontological systems as knowledge source, such as the computation of semantic distance between concepts and for ontology matching and alignment.

Results: This paper introduces a novel and scalable approach, called FEDRR – Fast, Exhaustive …


Fluctuations In A Cosmology With A Spacelike Singularity And Their Gauge Theory Dual Description, Robert H. Brandenberger, Elisa G. M. Ferreira, Ian A. Morrison, Yi-Fu Cai, Sumit R. Das, Yi Wang Oct 2016

Fluctuations In A Cosmology With A Spacelike Singularity And Their Gauge Theory Dual Description, Robert H. Brandenberger, Elisa G. M. Ferreira, Ian A. Morrison, Yi-Fu Cai, Sumit R. Das, Yi Wang

Physics and Astronomy Faculty Publications

We consider a time-dependent deformation of anti–de Sitter (AdS) space-time which contains a spacelike “singularity”—a spacelike region of high curvature. Making use of the AdS/CFT correspondence we can map the bulk dynamics onto the boundary. The boundary theory has a time dependent coupling constant which becomes small at times when the bulk space-time is highly curved. We investigate the propagation of small fluctuations of a test scalar field from early times before the bulk singularity to late times after the singularity. Under the assumption that the AdS/CFT correspondence extends to deformed AdS space-times, we can map the bulk evolution of …


Large Linear Magnetoresistance In Heavily-Doped Nb:Srtio3 Epitaxial Thin Films, Hyunwoo Jin, Keundong Lee, Seung-Hyub Baek, Jin-Sang Kim, Byung-Ki Cheong, Bae Ho Park, Sungwon Yoon, B. J. Suh, Changyoung Kim, Sung S. Ambrose Seo, Suyoun Lee Oct 2016

Large Linear Magnetoresistance In Heavily-Doped Nb:Srtio3 Epitaxial Thin Films, Hyunwoo Jin, Keundong Lee, Seung-Hyub Baek, Jin-Sang Kim, Byung-Ki Cheong, Bae Ho Park, Sungwon Yoon, B. J. Suh, Changyoung Kim, Sung S. Ambrose Seo, Suyoun Lee

Physics and Astronomy Faculty Publications

Interaction between electrons has long been a focused topic in condensed-matter physics since it has led to the discoveries of astonishing phenomena, for example, high-Tc superconductivity and colossal magnetoresistance (CMR) in strongly-correlated materials. In the study of strongly-correlated perovskite oxides, Nb-doped SrTiO3 (Nb:SrTiO3) has been a workhorse not only as a conducting substrate, but also as a host possessing high carrier mobility. In this work, we report the observations of large linear magnetoresistance (LMR) and the metal-to-insulator transition (MIT) induced by magnetic field in heavily-doped Nb:STO (SrNb0.2Ti0.8O3) epitaxial thin …