Physical Sciences and Mathematics Commons^™

Studies On Regulation Of Dihydrotestosterone Binding To And Releasing From The Androgen Receptor, Tahyra M. Resto Santos

Theses and Dissertations

The androgen receptor (AR) is a nuclear receptor that responds to testosterone and 5α-dihydrotestosterone (DHT) by modulating gene expression in a variety of cells, including prostate and muscle tissues. Studies of small molecule interaction with AR have shown diphenyl compounds inhibiting through a binding site labeled Binding Function 3 (BF3). The goal of this research is to analyze the interaction of the BF3 site with DDT and related compounds. Amino acids that are exposed on the surface of the BF3 that might interact with different compounds were mutated. Mutant proteins were tested experimentally for their impact on the inhibition the …

The Development Of Screening Platforms To Identify Novel Anti-Infectives That Inhibit Protein Synthesis In Pseudomonas Aeruginosa, Casey Anne Hughes

Theses and Dissertations

Pseudomonas aeruginosa, a Gram-negative opportunistic pathogen, is a leading cause of nosocomial infections and is becoming increasingly antibiotic resistant. Aminoacyl-tRNA synthetases (aaRSs) catalyze the covalent attachment of amino acids to their cognate tRNAs and serve as validated targets for the development of new anti-infectives. In P. aeruginosa, the genome contains two genes (tyrS and tyrZ) which encode two distinct TyrRS enzymes. The genes encoding both P. aeruginosa TyrRS-Z and TyrRS-S were cloned, overexpressed in E. coli cells, and purified to homogeneity. Both forms of TyrRS were active in aminoacylation and were developed into screening platforms using scintillation proximity …

Pm2.5 Data Reliability And Air Quality Improvement Trends In Beijing, Huimin Li

Theses and Dissertations

PM2.5 has been a main environmental concern due to its adverse effects on human health and society. We used data from two sources: monitoring station of the U.S. Embassy in Beijing, and several nearby monitoring stations of the Chinese Ministry of Environmental Protection. This study includes investigating (1) PM2.5 historical data reliability, (2) PM2.5 real-time data reliability, and (3) air quality improvement trends in Beijing over the past decade. We used graphical methods, descriptive statistics, correlation analysis, and inferential analyses including paired samples t-test, ANOVA, and Kruskal-Wallis test. We reported effect sizes to aid study on practical significance. Inferential procedures' …

Molten-Salt Synthesized Pyrochlore Nanoparticles For Multifunctional Applications, Jose P. Zuniga

Theses and Dissertations

There is a need in the scientific world to design and develop high quality nanomaterials with multifunctional applications. In this work, we explore the molten-salt method (MSS) as a new green method for the synthesis of complex metal oxides. We adjusted all synthesis parameters such as time, temperature and pH to generate an optimum La2Hf2O7 nanoparticle with a well define shape and surface. Activator ions such as Eu3+, Tb3+, Dy3+, Bi3+ and uranium ion (U4+, U6+) were used to monitor its structural and optical behavior effect when doped.

Our results showed effective quantum yield, thermal, pressure stability, near to white …

Existence And Classification Of Solutions To Nonlinear Elliptic Equations, Haseeb E. Ansari

Theses and Dissertations

The so-called Lane-Emden equation is a model in astrophysics, useful to problems in analysis and conformal geometry, and is closely related to the Yamabe Problem and the Uniformization Theorem. We discuss several important results for the equation, which include proving that the equation admits a distribution solution if and only if p is greater than the Serrin exponent, that classical solutions admit the form of a "bubble function" if p is equal to the Sobolev exponent, and no classical solutions exist for p less than the Sobolev exponent. A new proof of an extended result is also included.

Three Dimensional Carbon Nanotube Yarn Based Perovskite Solar Cells, Istiak Hussain

Theses and Dissertations

Perovskite solar cells (PSC) have emerged as a promising photovoltaic technology in lab scale with a short time of research due to their high power conversion efficiency, simple device fabrication, all solid-state structure and the possibility to ingrate the traditional device into fiber format. In this work, a three-dimensional (3D) perovskite solar cell is demonstrated using functionalized carbon nanotube yarn (CNT) as both cathode and anode. TiO2 and 2,2,7,-7-tetrakis(N,N-di-p-methoxyphenylamine)-9,9'-spirobifluorene (Spiro-OMeTAD) are used as the electron transporting and hole transporting material respectively. The TiO2 oxide layer is deposited on the top of the twisted carbon nanotube yarn and annealed with TiCl4 …

Contact Numbers For Packing Of Spherical Particles, Eduardo Alejandro Ramirez Martinez

Theses and Dissertations

This thesis covers packings of spherical particles. The main object of this investigation is the contact number of a packing. New bounds for contact numbers of certain families of sphere packings in dimension 3 are obtained as the outcome of this research.

Studying Mechanical And Structural Properties Of Β-Lg And Β-Cn Fibrils Using Atomic Force Microscopy, Hugo A. Villar

Theses and Dissertations

Amyloid fibrils from milk proteins have recently been the subject of extensive investigations in biophysics. The purpose of this thesis is to investigate the dynamics of fibrillation and the mechanical properties of β-LG and β-CN fibers using AFM-Quantitative Nanomechanical Mapping (QNM) and AFM-force spectroscopy. β-LG required one day of heating at 80 °C , pH 2 to fibrillate in solution; β-CN required three days. Using the AFM-QNM mode an average elastic modulus of 4.3 GPa was determined for the β-LG fibers and 3.1 GPa for β-casein fibers. A persistence length of 920 nm was determined using end to end distance …

Asymptotic Quantization For A Condensation System Associated With A Discrete Distribution, Shankar Parajulee

Theses and Dissertations

Let P := (1/3)P ○ S1–1 + (1/3)P ○ S2–1 + (1/3)v be a condensation measure on R, where S1(x) = (1/5)x, S2(x) = (1/5)x + 4/5 for all x ∈ R , and v is a discrete distribution on R with the support of v equals C := {(2/5), (3/5)}. For such a measure P we determine the optimal sets of n–means and the nth quantization errors for all n ≥ 2. In addition, we show that the quantization dimension of the condensation measure P exists and equals …

Effects On Altering Reaction Conditions In Suzuki Cross Coupling Reactions Using The Microwave, Javier Alejandro Perez

Theses and Dissertations

Over the last few decades, Suzuki coupling has become a common process for the synthesis of intermediates in pharmaceutical and industrial applications. It is well known that palladium is an effective catalyst for the formation of cross-coupled products. Therefore, this catalyst was tested in a series of reactions. Also, it is believed that other catalyst with similar properties to palladium can work, for example cerium. Therefore, a cerium hydroxide catalyst was synthesized in lab and used as a potential catalyst for the Suzuki reaction. For this study, some bases were investigated (NaOH, Na2CO 3, K3PO4, NaNO3, NaHCO3, etc) for the …

The Mathematical Aspects Of Theoretical Physics, Hassan Kesserwani

Theses and Dissertations

The aim of this thesis is to outline the mathematical machinery of general relativity, quantum gravity, cosmology and an introduction to string theory under one body of work. We will flesh out tensor algebra and the formalism of differential geometry. After deriving the Einstein field equation, we will outline its traditional applications. We then linearize the field equation by a perturbation method and describe the mathematics of gravitational waves and their spherical harmonic analysis. We then transition into the derivation of the Schwarzschild metric and the Kruskal coordinate transformation, in order to set the stage for quantum gravity. This sets …

Photocatalytic Degradation Of Simazine Using Zno/Go Composites, Kenneth Ray Flores

Theses and Dissertations

The photocatalytic degradation of simazine (SIM) by Zinc oxide/graphene oxide (ZnO/GO) composites, under visible light irradiation, was investigated to determine various reaction parameters, of initial pH, ZnO loading on GO, and catalyst mass. A pH of 2 was determined to be the optimal reaction pH for all ZnO/GO catalysts. A loading mass of 40mg for the 20 & 30mmol composites; whereas a 10mg mass was determined to be most effective for the 10mmol composite. The reaction followed second order kinetics for the degradation process, the reaction dependence was determined to be on the concentration of SIM in solution. All ZnO/GO …

Green Synthesis/Biosynthesis Of Silver Nanoparticles By Using Orange Peel Extract, Leela Joshi

Theses and Dissertations

Joshi, Leela, Green Synthesis/Biosynthesis of Silver Nanoparticles by Using Orange Peel Extract. Master of Science (MS), December, 2018, 40 pages, 23 figures, references, 36 titles. In this work, we report synthesis of silver nanoparticles (AgNPs) with an average size of ~6 nm. The aqueous solution of Ag+ ions is reduced using an aqueous extract from orange peel (Citrus Sinensis) at varying pHs. Reduction of Ag+ ions in solution was monitored using UV-visible absorption spectroscopy, and the corresponding surface plasmon resonance of AgNPs at 435 nm. The solution changed color from yellow to reddish-brown upon bioreduction of silver nitrate in orange …

Identities For Partitions Of N With Parts From A Finite Set, Acadia Larsen

Theses and Dissertations

We show for a prime power number of parts m that the first differences of partitions into at most m parts can be expressed as a non-negative linear combination of partitions into at most m – 1 parts. To show this relationship, we combine a quasipolynomial construction of p(n,m) with a new partition identity for a finite number of parts. We prove these results by providing combinatorial interpretations of the quasipolynomial of p(n,m) and the new partition identity. We extend these results by establishing conditions for when partitions of n with parts coming from …

Generalized &Thetas;-Parameter Peakon Solutions For A Cubic Camassa-Holm Model, Michael Rippe

Theses and Dissertations

In this paper we outline a method for obtaining generalized peakon solutions for a cubic Camassa-Holm model originally introduced by Fokas (1995) and recently shown to have a Lax pair representation and bi-Hamiltonian structure by Qiao et al (2012). By considering an amended signum function—denoted sgn &thetas;(x)—where sgn(0) = &thetas; for a constant &thetas;, we explore new generalized peakon solutions for this model. In this context, all previous peakon solutions are of the case &thetas; = 0. Further, we aim to analyze the algebraic quadratic equation resulting from a substitution of the single-peakon ansatz equipped with our amended …

Functionalized And Nanostructured Fibers For Photocatalysis And Energy Conversion, Jared R. Jaksik

Theses and Dissertations

Fiber-type / flexible materials present a unique opportunity for the incorporation of photocatalytic / energy generating technology, as they typically have a broad surface area exposed to light (clothing, curtains, carpet). In this work, several methods of harvesting incident light striking a flexible substrate to perform useful work are examined. In the first section a gold and silver nanoparticle augmented TiO2 thin film textile coating is evaluated for its self-cleaning / UV-protective / anti-microbial properties, and stability of the film / substrate over time is examined. In the second section a dye sensitized / hybrid type solar cell architecture based …

Design And Characterization Of An Affordable Laser Communication System, Andrea Tellez

Theses and Dissertations

Over the last decades, an exponential growth in communication demand has been observed. Radio Frequency (RF) band has been one of the most used bandwidths for data transmission in the world. Given the influence and the continuous growth of communication technology, the RF spectrum is overpopulated. More efficient systems are necessary to meet the communication needs of this generation. A change to optical bandwidth is the most practical alternative to deal with the congestion of radio frequency.

The aim of this thesis is to present the features of Free Space Optical links with off-the-shelf components. A description of how these …

Experimental And Computational Studies Of Rotation And Proton Tunneling In Organic Molecules And Molecular Dimers, Agapito Serrato Iii

Theses and Dissertations

An introduction to the relations of classical and quantum mechanics are presented in brief. As is an overview of the instrumentation and quantum chemical analysis performed to characterize the molecules presented in in this thesis. The pure rotational spectrum of 3,3,3-trifluoro-2(trifluoromethyl)propanoic acid, perfluorobutyric acid–formic acid dimer, and tropolone–formic acid dimer were measured using high-resolution microwave spectroscopy. The spectra have been observed using a cavity-based Fourier-transform microwave (FTMW) spectrometer and/or a chirped-pulse FTMW.

Design And Development Of Inquiry-Based Materials For Conducting Observational Astronomy Research At Utrgv, Americo Francisco Hinojosa Lee

Theses and Dissertations

The purpose of this work is to develop instructional materials to enhance the expertise of students in conducting observational astronomy research. The designed instructional units aim to provide students with an adequate knowledge of astronomy and hone their skills necessary in conducting observations, collecting and analyzing data including processing of astronomical images.

The instructional design is anchored on the ADDIE model (Analyze, Design, Develop, Implement and Evaluate). The phases from ADDIE were used as a framework to accomplish the process of developing the instructional materials. After following the ADDIE, it was possible to define performance goals and tasks which were …

Microwave-Assisted Ring-Opening Polymerization Of Poly(Ε-Caprolactone), Nancy Obregon

Theses and Dissertations

Poly(ϵ-caprolactone) (PCL) is a biodegradable polyester notorious by its promising properties and applications in the biomedical field. In this work, microwave-assisted ringopening polymerization (ROP) of ϵ-caprolactone (ϵ-CL) was performed. Stannous octoate [Sn(Oct)2] was used as catalyst with and without an alcohol initiator. The different initiators tested were glycerol, diethylene glycol (DEG) and poly(ethylene) glycol (PEG). Aiming to establish reaction parameters, the influence of different reaction times, temperatures, and monomer:initiator:catalyst ratios were examined. It was observed that the reaction was obtained and high molecular weight PCL was achieved successfully without an initiator. However, mixed results were obtained using an initiator. Products …

Removal Of Chromium(Vi) And Chromium(Iii) Ions From Aqueous Solution Using Bio-Char Generated From Agricultural Waste Products, Diego Fernando Gonzalez

Theses and Dissertations

Heavy metals are one of the most persistent and prevalent contaminants in the aquatic environment. The removal of chromium from aqueous solution, especially in the hexavalent form is difficult. New technologies, techniques and/or new materials have been designed in order to effectively and efficiently remove chromium from the aqueous environment. The project focuses on the comparison of the effects of pH, time, temperature, binding capacity on bio-char’ generated from agricultural waste produces vs an amino modified derivative of the bio-char. Pineapple skins were dried, ground, sieved, and pyrolyzed to produce a bio-char material. The bio-char was analyzed using FTIR to …

Carbon Nanotube Yarn Based Dye Sensitized Solar Cells With Enhanced Electron/Hole Pair Recombination Prevention Characteristics, Glenn E. Grissom

Theses and Dissertations

Carbon nanotube yarn based solar cells (CNTYSCs) show promise in a variety of applications such as military and smart fabrics. We use a highly aligned and interwoven Carbon nanotube yarn (CNTY) for the working electrode (WE) and counter electrode (CE), to create a flexible super strong, conductive, and photo active surface for the support of a calcined TiO2 nano-solution and macro-solution deposition as a base for added functionalizations of a dye-sensitized solar cell (DSSC) that is able to maintain its flexibility and integrity. The CNT fiber based solar cells have power conversion ability that is independent of the direction of …

Magnetic Phases Of Large-Spin Ultracold Bosons: Quantum Dimer Models And Spin Liquid Phases, Todd C. Rutkowski

Graduate Dissertations and Theses

This thesis investigates the plausibility of producing a quantum spin liquid (QSL) with ultracold bosonic atoms optically confined to the Mott insulating state. QSLs have received a great deal of attention for being an antiferromagnetic groundstate with many exotic properties, including the absence of local order, long-range entanglement, and fractionalized excitations. However, the identification and characterization of these phases in solid state systems remains a great challenge. Here we outline an alternate route to uncovering the QSL phase, which from the nature of spin angular momentum for ultracold atoms encounters many properties unique to these systems along the way. This …

On A Generalization Of The Hanoi Towers Group, Rachel Skipper

Graduate Dissertations and Theses

In 2012, Bartholdi, Siegenthaler, and Zalesskii computed the rigid kernel for the only known group for which it is non-trivial, theHanoi towers group. There they determined the kernel was the Klein 4 group. We present a simpler proof of this theorem. In thecourse of the proof, we also compute the rigid stabilizers and present proofs that this group is a self-similar, self-replicating, regular branch group.

We then construct a family of groups which generalize the Hanoi towers group and study the congruence subgroup problem for the groups in this family. We show that unlike the Hanoi towers group, the groups …

On A Pseudodifferential Calculus With Modest Boundary Decay Condition, Binbin Huang

Graduate Dissertations and Theses

A boundary decay condition, called vanishing to infinite logarithmic order is introduced. A pseudodifferential calculus, extending the b-calculus of Melrose, is proposed based on this modest decay condition. The mapping properties, composition rule, and normal operators are studied. Instead of functional analytic methods, a geometric approach is invoked in pursuing the Fredholm criterion. As an application, a detailed proof of the Atiyah-Patodi-Singer index theorem, including a review of Dirac operators of product type and construction of the heat kernel, is presented.

Oxidation Of Dibenzothiophene To Dibenzothiophene-Sufone Using A Molybdenum (Vi) Oxide Catalyst: A Kinetic Study Testing Solvent Dependency And Mole Ratio Efficiency, Tomas Trevino Jr.

Theses and Dissertations

Oxidative desulfurization (ODS) is currently a solution to hydrodesulphurization. Currently, industrial usage of hydrodesulphurization (HDS) is the common source for petroleum purification. Unfortunately, HDS comes with environmental and economical ramifications. Due to the problems and potential hazards being presented with HDS, ODS has become a topic of interest in research development. A kinetic study using molybdenum (VI) oxide as a catalyst was used in oxidative desulfurization. Factors such as mole ratio and solvent dependency were tested for efficiency. As activation energy was calculated to show maximum efficiency with respect to temperature and concentration. Gas Chromatography, FT-IR, and Mass Spectroscopy were …

Remediation Of Trivalent And Hexavalent Chromium Ions From Aqueous Solutions Using Titanium Dioxide Polymorphs, Yvette Cantu

Theses and Dissertations

Three titanium dioxide (TiO2) polymorphs were synthesized and used for the removal of chromium (III) and chromium (VI) from aqueous solutions. Various solution parameters were studied to determine the effects of pH, temperature, time, possible interfering ions, and capacities on the binding of Cr(III) and Cr(VI) to all three polymorphs. pH assays determined the optimum pH for the binding of both Cr(III) and Cr(VI) to each polymorph. Adsorption isotherms determined that the adsorption of Cr(III) was non-spontaneous for the three polymorphs with ΔG values ranging from 6.03 to 12.89 kJ/mol. Furthermore, the binding of Cr(VI) to anatase was also non-spontaneous …

Development Of An Innovative Observational Astronomy Class For High School Students In Collaboration With The University Of Texas/Rio Grande Valley, Alan W. Hendrick

Theses and Dissertations

The vision presented by the National Academy of Science Standards is for all students to spend more time ‘doing’ science in order to develop science literacy and be better prepared not only for college but also in understanding and participation in global current events. A course in observational Astronomy is just that, an opportunity for student to “do ‘science by collaborating with actual scientists in real research. The course follows a path in which students learn foundational knowledge and apply this knowledge to complete a successful celestial observation, interpreting the results by making inferences and predictions. This paper begins with …

Hydrodesulfurization Of Dibenzothiophene Using Lanthanum Doped Comos2, Carolina Valdes Bracamontes

Theses and Dissertations

Hydrodesulfurization (HDS) is a technique used in petrochemical industry for the removal of sulfur from crude oil. Using dibenzothiophene (DBT) as a target molecule and CoMoS2 catalysts doped with various concentrations of lanthanum were studied for catalytic activity in the removal of DBT from solution. Catalysts were synthesized using ammonium tetrathiomolydate, cobalt chloride and lanthanum nitrate under a solvothermal decomposition in decalin at 350 °C with H2 gas at 160 psi. To evaluate decomposition effects, a second set of catalyst precursors were decomposed in a tube furnace at 450 °C under a constant flow of 10%/90% H2/Ar. Characterizations of the …

Synthesis Of Tetraethyl ((2-Amino-1,4-Phenylene)Bis(Methylene)) Bis(Phosphonate): An Intermediate In The Synthesis Of Amino-Substituted Conjugated Materials, Ariel Ivan Torres Burgueno

Theses and Dissertations

Discussed here are the syntheses of the phosphonate precursors for the Wittig-Horner synthesis of poly-phenylene vinylene (PPV) and distyrylbenzene (DSB) derivatives and their respective distyrylbenzene analogs containing amino moieties. The synthesis of the different compounds was achieved through bromination, Michaelis-Arbuzov reaction, reduction of the nitro group with a commercial cobalt sulfide catalyst and sodium borohydride. Preliminary evidence for the synthesis of amino substituted distyrylbenzene and of nitro/alkoxy substituted poly(p-phenylene vinylene) was obtained. Characterization of the products was performed by 1H-NMR. Preliminary results of the synthesis of a novel amino-substituted distyrylbenzene (DSB) are presented. The luminescence of the new DSB was …