Physical Sciences and Mathematics Commons^™

Multi-Label Model For Toxicity Prediction, Xiu Huan Yap, Michael L. Raymer

Symposium of Student Research, Scholarship, and Creative Activities Materials

Most computational predictive models are specifically trained for a single toxicity endpoint. Since more than 1300 toxicity assays have been reported in the TOXCAST dashboard, achieving high coverage over this growing number of toxicity endpoints remains challenging. Furthermore, single-endpoint models lack the ability to learn dependencies between endpoints, such as those targeting similar biological pathways, which may be used to boost model performance. In this study, we characterize the performance of 3 multi-label classification (MLC) models, namely Classifier Chains (CC), Label Powersets (LP) and Stacking (SBR), on Tox21 challenge data. These MLC models employ the Problem Transformation approach, which is …

Measuring Nomophobia And Exploration Of Consequences And Comorbidities, Sarah Marie Fryman, William L. Romine

Symposium of Student Research, Scholarship, and Creative Activities Materials

Excessive use of smartphones has coined the term “Nomophobia”, or fear of not being able to use your smartphone. For many, these devices have become an extension of ourselves, which raises hesitation on whether or not society has become addicted to smartphones. Specific diagnostic criteria for smartphone addiction have yet to be settled, and even appropriate to use the word “addiction” when describing excessive usage of smartphones is controversial.

We therefore explore utilize current measures to explore the symptoms of nomophobia and their hierarchy, as well as comorbidities including social anxiety, self-esteem, distracted driving and sleep quality. A total of …

Wright State University's Symposium Of Student Research, Scholarship & Creative Activities From Friday April 13, 2018, Wright State University

Symposium of Student Research, Scholarship, and Creative Activities Materials

The student abstract booklet is a compilation of abstracts from students' oral and poster presentations at Wright State University's Symposium of Student Research, Scholarship & Creative Activities on April 13, 2018.

Khealth Bariatrics: A Multisensory Approach To Monitoring Patient’S Postsurgical Behavior, Revathy Venkataramanan, Utkarshani Jaimini, Amit Sheth, Joon K. Shim, Priti Parikh, Dene S. Berman

Symposium of Student Research, Scholarship, and Creative Activities Materials

The rate of obesity is on the rise reaching epidemic proportions. According to American Society for Metabolic and Bariatric Surgery (ASMBS), 500 million people all over the world are obese. The data from Centers for Disease Control and Prevention(CDC) shows that more than 36% of adults in the United States have obesity. According to World Health Organization (WHO), 65% of the world’s population lives in countries where the occurrence of death due to overweight and obesity is higher than being underweight. It is well established that weight loss surgery can play a significant role in reducing, or even eliminating medical …

Measuring Gender-Based Violence Attitude On Twitter, Goonmeet Bajaj, Tanvi Banerjee, Amir Hossein Yazdavar, Valerie L. Shalin, Amit Sheth

Symposium of Student Research, Scholarship, and Creative Activities Materials

This study examines social media to analyze communication patterns, specifically in the Gender-Based Violence domain. It explores the pragmatic content of tweets to categorize them into one of the following groups: Belief, Fact Reporting, or Other to determine the tweeting practices prevalent in this domain.

Legalization Of Gay Marriage And Its Impact On Military Stereotypes Of Homosexuals, Jasmine Moore

Symposium of Student Research, Scholarship, and Creative Activities Materials

Homosexuality has become a popular research topic in a variety of professional fields, and over the last decade has become a priority for the military. Since the implementation of the law repealing Don't Ask Don't Tell (DADT) researchers have questioned what effects repealing this law has had on the military as a whole. Particular attention has been spent on studying the attitudes and stereotypes about homosexuals after DADT was repealed. However, there is a lack of research examining how marriage equality affects society's stereotypes about homosexuals serving in the United States military.

It was hypothesized that participants that have personal …

Wright State University's Celebration Of Research, Scholarship And Creative Activities Book Of Abstracts From Friday, April 21, 2017, Wright State University

Symposium of Student Research, Scholarship, and Creative Activities Materials

The student abstract booklet is a compilation of abstracts from students' oral and poster presentations at Wright State University's Annual Celebration of Research, Scholarship and Creative Activities on April 21, 2017.

Treating Chronic Post Herpetic Neuralgia Using Topical Superconcentrated Capsaicin, Jaree Naqvi, Scott Seider, Jason Miller, Cole Budinsky, Amol Soin

Symposium of Student Research, Scholarship, and Creative Activities Materials

Post Herpetic Neuralgia (PHN) is a painful condition that occurs after reactivation of the dormant Herpes Zoster Virus.Typically PHN presents with a unilateral rash affecting a single dermatome which is accompanied by burning, irritation, and hypersensitivity for >3 months.Current treatment includes anticonvulsants, tricyclic antidepressants, narcotic/nonnarcotic painkillers, and topical lidocaine.

We propose the utilization of a superconcentrated transdermal patch of capsaicin called Qutenza 8%, which is 300 times more potent than current OTC capsaicin. The treatment protocol using Qutenza to treat refractory PHN proposes a novel approach to the treatment of this condition.

Capsaicin is commonly known as the active chemical …

Social Workers’ Salaries Vs. Educational Student Debt Burden: A Losing Battle, Michael Wadham

Symposium of Student Research, Scholarship, and Creative Activities Materials

College tuitions rise at disparate rates with starting salaries and inflation, causing student debt to weigh on social work graduates. Data was collected from 701 social workers in an NASW - Ohio Chapter survey to investigate this disparity and its consequences. The purpose of this study was to analyze the qualitative data set, 174 written comments, for themes and perceptions. The following themes, echoed in current research on the topics of social work salary and student debt burden, were identified: unmanageable debt and financial burden, varying lengths of time and repayment methods, social workers feeling undervalued and underpaid, loan forgiveness …

Comparing Network Centrality Measures Of Non-Traditional Students In An Introductory Physics Class, Emily N. Sandt, Adrienne L. Traxler

Symposium of Student Research, Scholarship, and Creative Activities Materials

The goal of this research was to compare different models of network influence for students. Two research questions were composed: 1. How do common centrality measures compare when ranking students' network influence? 2. Do centrality values of non-traditional students show different trend than traditional students?

Finding Specific, Topic Related Information From A Sea Of Social Media Posts, Scott J. Duberstein, Daniel Asamoah, Derek Doran, Shu Z. Schiller

Symposium of Student Research, Scholarship, and Creative Activities Materials

As social media continues to become an incredible mode of communication in daily life dealing with the exchange of information, these systems provide authors a platform where they can share their thoughts, feelings, and experiences about a number of topics. Harnessing the information expressed publicly through these modes can be incredibly powerful: public perceptions, signals, and data about a variety of specific topics could be extracted and studied from these posts. However, there is a common trade-off in collecting information about a topic from social media: the more specific the topic, generally, the more challenging it is to extract meaningful …

Investigating The After-Effects Of Stochastic Resonance For Use In Laparoscopic Surgery, Muhammad S. Hamdan, Caroline G. L. Cao

Symposium of Student Research, Scholarship, and Creative Activities Materials

Laparoscopic surgery is a modern surgical technique in which surgeons insert tools through small incisions in the abdomen to perform a surgical procedure.

Nondestructive Evaluation & Radar Imaging Using Terahertz Signals, D. Amal Mirando, Michael D. Higgins, Sonya Sokhey, Matthew Larson, Douglas T. Petkie

Symposium of Student Research, Scholarship, and Creative Activities Materials

Nondestructive imaging is a method of examining a material without direct contact that additionally does not alter the properties of the material. The terahertz imaging system currently in development uses the principle of interferometry (a Michelson Interferometer) such that frequency modulated terahertz signals are split and directed to the object under study and a reference mirror; then the detector will acquire the intensity of the combined reflected signals that contains information about the objects in the path of the beam.

Evaluation Of A Brief Marriage Intervention For Internal Behavioral Health Consultants In Military Primary Care, Ashley L. Evans, Jeffrey A. Cigrang, Tatiana D. Grey, James V. Cordova, Elizabeth Najera, Rosalyn S. Pace, Abby D. Fields, Michael A. Glotfelter, Jennifer A. Mitchell, Jolyn Tatum

Symposium of Student Research, Scholarship, and Creative Activities Materials

Military couples face significant challenges to their relationships including demanding schedules, multiple deployments, and frequent moves. Despite the high costs of chronic marital distress, very few military (or civilian) couples seek marriage therapy. The military services and the VA system have implemented collaborative care models in primary care where internal behavioral health consultants are integrated into primary care. Integrated primary care can reduce the stigma of behavioral health services and may increase the odds that couples would seek help earlier. There are no established couple interventions designed for use in primary care. The purpose of this presentation is to describe …

Synthesis Of Functionalized Peek Analogues Via “One-Pot” Synthesis, Zachary B. Ewing, Eric A. Fossum

Symposium of Student Research, Scholarship, and Creative Activities Materials

Poly(arylene ether)s, PAEs

• High performance engineering thermoplastic materials

• Excellent mechanical properties and thermal stability

• Resistant to hydrolysis and oxidation

• Many prepared via nucleophilic aromatic substitution (NAS)

• Electron withdrawing groups (EWG) typically in para positions

• PAEs can also be synthesized with an EWG in the meta positions, creating easily functionalized systems, with no change in the backbone

Wright State University's Celebration Of Research, Scholarship And Creative Activities Book Of Abstracts From Friday, April 15, 2016, Wright State University Office Of Undergraduate Research And Stemm Activities

Symposium of Student Research, Scholarship, and Creative Activities Materials

The student abstract booklet is a compilation of abstracts from students' oral and poster presentations at Wright State University's Annual Celebration of Research, Scholarship and Creative Activities on April 15, 2016.

City360: Visualizing Multimodal City Events For Decision Support, Vaikunth Sridharan, Tanvi Banerjee, Pramod Anantharam, Archana Sheshadri, Roopteja Muppalla, Amit P. Sheth, Krishnaprasad Thirunarayan

Symposium of Student Research, Scholarship, and Creative Activities Materials

Cities are increasingly outfitted with sensors for monitoring various conditions such as traffic, weather, air quality, and infrastructure related issues. Such well outfitted cities are generating massive amounts of multi-modal data leading to daunting challenges in assimilating, visualizing, and making sense of this data by city authorities and citizens. We propose City360 to address these challenges and provide decision support to city authorities and citizens. We demonstrate the utility of our system through concrete use cases for San Francisco Bay area that utilize heterogeneous data from various open city data sources.

Wright State University's Celebration Of Research, Scholarship And Creative Activities Book Of Abstracts From Friday, April 10, 2015, Wright State University Office Of Undergraduate Research And Stemm Activities

Symposium of Student Research, Scholarship, and Creative Activities Materials

The student abstract booklet is a compilation of abstracts from students' oral and poster presentations at Wright State University's fifth annual Celebration of Research, Scholarship and Creative Activities on April 10, 2015.

No Oasis In The Desert: Identification And Implications Of The Food Desert Around An Urban Ohio Hospital, R. J. Sontag

Symposium of Student Research, Scholarship, and Creative Activities Materials

Montgomery County, Ohio’s diabetes prevalence outpaces the nation, and the incidence of adult obesity approaches 1/3. Access to healthy food in the impoverished neighborhood surrounding Dayton’s Good Samaritan Hospital, the site of the Family Medicine residency, is important when educating about health lifestyle. The purpose of this project was to determine whether the area was a food desert and to evaluate the implications of the label.

Characterization Of Calbindin Positive Interneurons Within The Ventral Horn Of The Mouse Spinal Cord, Taylor L. Floyd, David R. Ladle

Symposium of Student Research, Scholarship, and Creative Activities Materials

Sensory-motor circuits in the spinal cord integrate sensory feedback from muscles and modulate locomotor behavior. Although we know how the sensory-motor system generally works, the main issue lies in identifying all neurons involved and understanding their interrelationships. Many interneurons contribute to sensory-motor circuits and have been well studied. For example, Renshaw cells (RC) are inhibitory interneurons that prevent motor neurons from over-activity. A distinguishing feature of RCs is that they are the only interneurons within the ventral-most region of the spinal cord expressing the calcium binding protein calbindin (CB). Recent studies have found other subpopulations of ventral horn interneurons outside …

Expression Of The Nkcc2a Cotransporter In Mouse Central Nervous System, Katherine E. Fahy, James B. Lucot, Hayo Castrop, Mauricio Di Fulvio

Symposium of Student Research, Scholarship, and Creative Activities Materials

Na-K-2Cl cotransporter 2A (NKCC2A), also known as the bumetanide-sensitive cotransporter 1 (BSC1), transports Na+, K+ and Cl- with a stoichiometry of 1:1:2. NKCC2A is considered a kidney specific cotransporter. It is abundantly expressed in apical membrane of the tubular cells in the thick ascending limb of the loop of Henle (TALH) and in the macula densa. However, NKCC2 has also been found at low levels in different cells, including insulin-secreting ones. This secondary active transporter uses the energy stored in the electrochemical gradients of Na and K maintained by the Na/K-ATPase located on the basolateral membrane of the TALH. The …

High Power Pulsed Terahertz Light Generation From Superconducting Antenna Arrays, Nicholas C. Padgett, Stephanie R. Lake, Jason A. Deibel, T. Bullard, D. Latypov, J. Patel, J. Murphy, J. Bulmer, W. Tang, M. Sebastian, Timothy J. Haugan

Symposium of Student Research, Scholarship, and Creative Activities Materials

Terahertz radiation is invaluable in spectroscopy and imaging due to its nondestructive nature. It has become a key focus for those wishing to develop sensors capable of detecting weapons and narcotics unobtrusively and at a distance. An ultrafast pulsed (femtoseconds) laser incident on a superconducting ring causes the emission of terahertz (THz) radiation. It is theorized that the radiation is a result of the supercurrent being modulated by the breaking and recombining of Cooper pairs on the order of picoseconds, where the time scale determines the frequency of the emitted radiation. We propose to investigate the terahertz emission from Yttrium …

Wright State University's Celebration Of Research, Scholarship, And Creative Activities Book Of Abstracts From Friday, April 11, 2014, Wright State University Office Of Undergraduate Research And Stemm Activities

Symposium of Student Research, Scholarship, and Creative Activities Materials

The student abstract booklet is a compilation of abstracts from students' oral and poster presentations at Wright State University's second annual Celebration of Research, Scholarship and Creative Activities on April 11, 2014.

Student Growth Measures For Teacher And Principal Evaluations, Suzanne Franco, Allison Mueller

Symposium of Student Research, Scholarship, and Creative Activities Materials

There were three Ohio research efforts about Student Growth Measures (SGM) for Teacher and Principal Evaluations: 1) extended testing for previously non-­‐tested subjects and grades, 2) relationship between the teacher and principal evaluation systems’ implementation plans, and 3) an empirical study of Local Education Agencies’ (LEA) year-­‐end evaluation data from 2013. In 2011-­‐2012 Ohio offered a 2 year mini-­‐grant to LEAs agreeing to administer extended testing for Value-­‐Added measures (VAM) in grades and content areas not represented in the Ohio Achievement Assessment (OAA). The mini-­‐grant allowed the state to create testing pools sufficient to produce teacher-­‐level VAMs. American College Testing …

The Role Of The Nurse In Family Coping After Miscarriage, Wesley Hannebaum

Symposium of Student Research, Scholarship, and Creative Activities Materials

When a miscarriage occurs, it affects the entire family unit, making coping an important part of healing during this time. After miscarriage, women are at increased risk for developing mental disorders such as anxiety and depression. Miscarriage is seldom seen as a concern for the father of the lost child, and thus their feelings are often ignored. It is important for the nurse to know how to best help these men, women, and the rest of the involved family cope after miscarriage so they can move on in a healthy way. The following is a review of the literature to …

Wright State University Celebration Of Research, Scholarship And Creative Activities Book Of Abstracts Friday, April 12, 2013, Wright State University Office Of Undergraduate Research And Stemm Activities

Symposium of Student Research, Scholarship, and Creative Activities Materials

The student abstract booklet is a compilation of abstracts from students' oral and poster presentations at Wright State University's second annual Celebration of Research, Scholarship and Creative Activities on April 12, 2013.

Wright State University Celebration Of Research, Scholarship And Creative Activities Book Of Abstracts Friday, April 13, 2012, Wright State University Office Of Undergraduate Research And Stemm Activities

Symposium of Student Research, Scholarship, and Creative Activities Materials

The student abstract booklet is a compilation of abstracts from students' oral and poster presentations at Wright State University's second annual Celebration of Research, Scholarship and Creative Activities on April 13, 2012.

Eti‐385 As A Novel Anti‐Emetic Against Drug Induced Emesis, Theresa Fennell, James Lucot, Samantha Spitak, Emily Smith, Teresa Garret

Symposium of Student Research, Scholarship, and Creative Activities Materials

Drugs currently used to prevent emesis (nausea and vomiting) target only one or a few of the pathways used by emetic stimuli to trigger the reflex. Thus, an anti-emetic drug will only be effective against some stimuli. Prior work determined that 8-OH-DPAT (DPAT, a 5-HT1A agonist) was a universally effective anti-emetic. Although DPAT prevented emesis, it also elicited an extreme anxiety response making it unsuitable for therapeutic use. Presently, there exists no universal anti-emetic drug. We tested a proprietary drug developed from DPAT, ETI-385, which successfully prevented emesis in musk shrews against chemotherapy, drug and motion stimuli. For FDA purposes, …

Wright State University Celebration Of Research, Scholarship And Creative Activities Book Of Abstracts Friday, April 8, 2011, Wright State University Office Of Undergraduate Research And Stemm Activities

Symposium of Student Research, Scholarship, and Creative Activities Materials

The student abstract booklet is a compilation of abstracts from students' oral and poster presentations at Wright State University's second annual Celebration of Research, Scholarship and Creative Activities on April 8, 2011.

Role Of The 3'Lghrr In Tcdd-Induced Suppression Of The Immunoglobulin Heavy Chain, Jayharsh L. Panchal, Eric J. Romer, David Ellis, Tharu Fernando, Courtney E. W. Sulentic

Symposium of Student Research, Scholarship, and Creative Activities Materials

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) inhibits antibody secretion and immunoglobulin heavy chain (IgH) expression. Our previous work has shown that a possible mechanism for inhibition of IgH expression could be inhibition of the 3’IgH regulatory region (3’IgHRR). The 3’IgHRR has four enhancer regions (hs3a; hs1,2; hs3b; hs4) which are purported to control IgH gene expression. Previously we demonstrated a sensitive inhibition by TCDD of LPS-induced 3’IgHRR activity which is correlated with an inhibition of LPS-induced hs1,2 enhancer activity; however, the hs4 enhancer showed TCDD-induced activation following the co-treatment of TCDD and LPS. Therefore, the objective of the current study was to determine if …