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Rhetorics Of Species Revivalism And Biotechnology – A Roundtable Dialogue, Eva Kasprzycka, Charlotte Wrigley, Adam Searle, Richard Twine Jan 2023

Rhetorics Of Species Revivalism And Biotechnology – A Roundtable Dialogue, Eva Kasprzycka, Charlotte Wrigley, Adam Searle, Richard Twine

Animal Studies Journal

This informal dialogue contextualises and explores contemporary practices of nonhuman animal gene-modification in de-extinction projects. Looking at recent developments in biotechnology’s role in de-extinction sciences and industries, these interdisciplinary scholars scrutinise the neoliberal impetus driving ‘species revivalism’ in the wake of the Capitalocene. Critical examinations of species integrity, cryo-preservation, techno-optimism, rewilding initiatives and projects aimed at restoring extinct animals such as the woolly mammoth and bucardo are used to map some of the necessary restructuring of conservation policies and enterprises that could secure viably sustainable – and just – futures for nonhuman animals at risk of extinction. The authors question …


The Illegal Wildlife Trade: Through The Eyes Of A One-Year-Old Pangolin (Manis Javanica), Lelia Bridgeland-Stephens Jan 2020

The Illegal Wildlife Trade: Through The Eyes Of A One-Year-Old Pangolin (Manis Javanica), Lelia Bridgeland-Stephens

Animal Studies Journal

This paper explores the literature on the illegal wildlife trade (IWT) by following the journey of a single imagined Sunda pangolin (Manis javanica) through the entire trading process. Literature on IWT frequently refers to non-human animals in terms of collectives, species, or body parts, for example ‘tons of pangolin scales’, rather than as subjective individuals. In contrast, this paper centralizes the experiences of an individual pangolin by using a cross- disciplinary methodology, combining fact with a fictional narrative of subjective pangolin experience, in an empathetic and egomorphic process. The paper draws together known legislation, trade practices, and pangolin biology, structured …


Forum Proceedings From “Uavs: Pros Vs Cons Symposium” In Toronto, Canada, June 2013, Katina Michael Feb 2014

Forum Proceedings From “Uavs: Pros Vs Cons Symposium” In Toronto, Canada, June 2013, Katina Michael

Associate Professor Katina Michael

Unmanned Aerial Systems (UAS), widely referred to as drones, are becoming increasingly relevant in civilian as well as military applications. UAS have been used by emergency services to help respond to and map environmental crises, to find missing people, to fight fires, and respond to traffic accidents. Their use in policing and border patrol functions is being trialled in many Western countries. Like other recent technologies (mobile phones etc), as they become cheaper and easier to use, they are likely to become much more prevalent in civilian life across a range of applications.

This conference will examine the current state …


Induced Pluripotent Stem Cells As Tools For Disease Modelling And Drug Discovery In Alzheimer's Disease, Lezanne Ooi, Kuldip Sidhu, Anne Poljak, Greg Sutherland, Michael D. O'Connor, Perminder Sachdev, Gerald Munch Jan 2013

Induced Pluripotent Stem Cells As Tools For Disease Modelling And Drug Discovery In Alzheimer's Disease, Lezanne Ooi, Kuldip Sidhu, Anne Poljak, Greg Sutherland, Michael D. O'Connor, Perminder Sachdev, Gerald Munch

Faculty of Science - Papers (Archive)

Alzheimer’s disease (AD) is a progressive neurodegenerative brain disorder that leads to a progressive decline in a person’s memory and ability to communicate and carry out daily activities. The brain pathology in AD is characterized by extensive neuronal loss, particularly of cholinergic neurons, intracellular neurofibrillary tangles composed of the tau protein (NFTs) and extracellular deposition of plaques composed of β-amyloid (Aβ), a cleavage product of the amyloid precursor protein (APP). These two insoluble protein aggregates are accompanied by a chronic inflammatory response and extensive oxidative damage. Whereas dys-regulation of APP expression or processing appears to be important for the familial, …


A Reagentless Thermal Post-Synthetic Rearrangement Of An Allyloxy-Tagged Metal-Organic Framework, Andrew D. Burrows, Sally O. Hunter, Mary F. Mahon, Christopher Richardson Jan 2013

A Reagentless Thermal Post-Synthetic Rearrangement Of An Allyloxy-Tagged Metal-Organic Framework, Andrew D. Burrows, Sally O. Hunter, Mary F. Mahon, Christopher Richardson

Faculty of Science - Papers (Archive)

Direct heating of a metal-organic framework provides a simple, controllable way of effecting a covalent post-synthetic modification. Herein we report that an allyloxy-tagged zinc metal-organic framework undergoes a thermally-promoted aromatic Claisen rearrangement through which the framework connectivity and porosity are maintained.


Ten Trenches: A Scienceart Collaboration, Timothy J. Cohen, Martin Cohen, Stephanie Kermode, Michael G. Leggett Jan 2013

Ten Trenches: A Scienceart Collaboration, Timothy J. Cohen, Martin Cohen, Stephanie Kermode, Michael G. Leggett

Faculty of Science - Papers (Archive)

Collaborative and cross-disciplinary research by a group of artists and scientists in an Australian rural setting generates data and ideas that form the basis of a wider understanding of the ramifications of global warming and cooling within the local, regional and national community. The work is viewed as an initial educational platform that will allow the public to see and understand the complexities of climate-based research.


Privacy Issues And Solutions In Social Network Sites, Xi Chen, Katina Michael Dec 2012

Privacy Issues And Solutions In Social Network Sites, Xi Chen, Katina Michael

Associate Professor Katina Michael

The boom of the internet and the explosion of new technologies have brought with them new challenges and thus new connotations of privacy. Clearly, when people deal with e-government and e-business, they do not only need the right to be let alone, but also to be let in secret. Not only do they need freedom of movement, but also to be assured of the secrecy of their information. Solove [6] has critiqued traditional definitions of privacy and argued that they do not address privacy issues created by new online technologies. Austin [7] also asserts: “[w]e do need to sharpen and …


Indian Millennials: Are Microchip Implants A More Secure Technology For Identification And Access Control?, Christine Perakslis, Katina Michael Oct 2012

Indian Millennials: Are Microchip Implants A More Secure Technology For Identification And Access Control?, Christine Perakslis, Katina Michael

Associate Professor Katina Michael

This mixed methods study with a sequential explanatory strategy explored qualitatively the statistically significant quantitative findings relative to Indian respondents’ perceptions about RFID (radio frequency identification) transponders implanted into the human body. In the first analysis phase of the study, there was a significant chi-square analysis reported (χ2 = 56.64, df = 3, p = .000) relative to the perception of small business owners (N = 453) that implanted chips are a more secure form of identification and/or access control in organizations and the respondents’ country of residence. Countries under study included Australia, India, the UK and US. The country …


Bryophyte Species Composition Over Moisture Gradients In The Windmill Islands, East Antarctica: Development Of A Baseline For Monitoring Climate Change Impacts, J Wasley, S A. Robinson, J D. Turnbull, D H. King, W Wanek, M Popp Oct 2012

Bryophyte Species Composition Over Moisture Gradients In The Windmill Islands, East Antarctica: Development Of A Baseline For Monitoring Climate Change Impacts, J Wasley, S A. Robinson, J D. Turnbull, D H. King, W Wanek, M Popp

Faculty of Science - Papers (Archive)

Extreme environmental conditions prevail on the Antarctic continent and limit plant diversity to cryptogamic communities, dominated by bryophytes and lichens. Even small abiotic shifts, associated with climate change, are likely to have pronounced impacts on these communities that currently exist at their physiological limit of survival. Changes to moisture availability, due to precipitation shifts or alterations to permanent snow reserves, will most likely cause greatest impact. In order to establish a baseline for determining the effect of climate change on continental Antarctic terrestrial communities and to better understand bryophyte species distributions in relation to moisture in a floristically important Antarctic …


The Value Of Government Mandated Location-Based Services In Emergencies In Australia, Anas Aloudat, Katina Michael, Roba Abbas, Mutaz Al-Debei Jul 2012

The Value Of Government Mandated Location-Based Services In Emergencies In Australia, Anas Aloudat, Katina Michael, Roba Abbas, Mutaz Al-Debei

Associate Professor Katina Michael

The adoption of mobile technologies for emergency management has the capacity to save lives. In Australia in February 2009, the Victorian Bushfires claimed 173 lives, the worst peace-time disaster in the nation’s history. The Australian government responded swiftly to the tragedy by going to tender for mobile applications that could be used during emergencies, such as mobile alerts and location services. These applications, which are becoming increasingly accurate with the evolution of positioning techniques, have the ability to deliver personalized information direct to the citizen during crises, complementing traditional broadcasting mediums like television and radio. Indeed governments have a responsibility …


The Isolation Of Bioactive Flavonoids From Jacaranda Obtusifolia H. B. K. Ssp. Rhombifolia (G. F. W. Meijer) Gentry, Sorachai Khamsan, Saisunee Liawruangrath, Aphiwat Teerawutkulrag, Stephen G. Pyne, Mary J. Garson, Boonsom Liawruangrath Jun 2012

The Isolation Of Bioactive Flavonoids From Jacaranda Obtusifolia H. B. K. Ssp. Rhombifolia (G. F. W. Meijer) Gentry, Sorachai Khamsan, Saisunee Liawruangrath, Aphiwat Teerawutkulrag, Stephen G. Pyne, Mary J. Garson, Boonsom Liawruangrath

Faculty of Science - Papers (Archive)

The paper describes the bioassay-guided isolation, structure elucidation and anticancer evaluation of five flavonoids (-)-liquiritigenin (1), (-)-neoliquiritin (2), isoliquiritigenin (3), isoliquiritin (4) and formononetin (5) from the twigs of Jacaranda obtusifolia H. B. K. ssp. rhombifolia (G. F. W. Meijer) Gentry. The structures were elucidated based on 1H, 13C NMR, comprehensive 2D NMR, MS analyses and comparison with previously reported spectral data. Compounds 1 and 3 were demonstrated to be inhibitory in vitro against NCI-H187 (small cell lung cancer) with IC50 values of 30.1 and 16.6 μg mL-1, respectively. The isolates were non-cytotoxic to Vero cells (African green monkey kidney).


Translocation Of The Eastern Bristlebird 1: Radio-Tracking Of Post-Release Movements, David Bain, Kris French, Jack Baker, Jean Clarke May 2012

Translocation Of The Eastern Bristlebird 1: Radio-Tracking Of Post-Release Movements, David Bain, Kris French, Jack Baker, Jean Clarke

Faculty of Science - Papers (Archive)

Translocating birds to a new area of habitat to restore or supplement depleted populations may pose a significant threat to the translocated individuals. While for many species, translocated individuals appear to move larger distances than resident animals, species with poor dispersal capacity may be restricted in movements and translocation methods may need to accommodate differences in movements to ensure success. In this study, designed to provide insights to inform our broader programme of translocations in New South Wales, Australia, we investigated post-release movements in the endangered, semi-flightless Eastern Bristlebird (Dasyornis brachypterus). We predicted that movements would be minimal, with few …


Manufacturing On The Move? Beyond The High Dollar In The Debate About Making Things In Australia - The Case Of The Australian Surfboard Industry - Ausccer Discussion Paper No. 2012/2, Andrew Warren, Chris Gibson May 2012

Manufacturing On The Move? Beyond The High Dollar In The Debate About Making Things In Australia - The Case Of The Australian Surfboard Industry - Ausccer Discussion Paper No. 2012/2, Andrew Warren, Chris Gibson

Faculty of Science - Papers (Archive)

In October 2011 surfboard manufacturer BASE abruptly closed its factory on the Gold Coast resulting in the direct loss of 50 jobs. A few days later, nearby D’Arcy Surfboards also announced it was shedding workers and downsizing from a state-of-the art purpose built factory into a backyard workshop. Each business exported surfboards internationally and employed some of Australia’s best known surfboard-makers. The troubles facing these workshops added to those brewing at the very same in Australia’s steel, aluminium, automotive and garment industries. With renewed public debate and media commentary on the future of manufacturing, we now face a crisis in …


Commentary On: Mann, Steve (2012): Wearable Computing, Katina Michael, M.G. Michael Apr 2012

Commentary On: Mann, Steve (2012): Wearable Computing, Katina Michael, M.G. Michael

Associate Professor Katina Michael

In Professor Steve Mann- inventor, physicist, engineer, mathematician, scientist, designer, developer, project director, filmmaker, artist, instrumentalist, author, photographer, actor, activist- we see so much of the paradigmatic classical Greek philosopher. I recall asking Steve if technology shaped society or society shaped technology. He replied along the lines that the question was superfluous. Steve instead pointed to praxis, from which all theory, lessons or skills stem, are practiced, embodied and realized. Steve has always been preoccupied by the application of his ideas into form. In this way too, he can be considered a modern day Leonardo Da Vinci.


Book Review: Securing The Cloud: Cloud Computer Security Techniques And Tactics, Katina Michael Apr 2012

Book Review: Securing The Cloud: Cloud Computer Security Techniques And Tactics, Katina Michael

Associate Professor Katina Michael

With so much buzz around Cloud Computing, books like this one written by Winkler are much in demand. Winkler’s experience in the computing business shines through and as readers we are spoiled with a great deal of useful strategic information- a jam packed almost 300 page volume on securing the cloud.


In Memoriam: Associate Professor Dr Elaine Lawrence, Katina Michael Apr 2012

In Memoriam: Associate Professor Dr Elaine Lawrence, Katina Michael

Associate Professor Katina Michael

Despite being a graduate of the rigorous Bachelor of Information Technology at the University of Technology, Sydney (UTS) in 1996, I was unfortunate in that I missed being taught by Associate Professor Elaine Lawrence who began working at UTS in 1990 as a Lecturer in Computing Science. Dr Lawrence became a senior lecturer in 2000, and subsequently an associate professor in 2006. Our paths crossed in 2002 when I was tasked to deliver a new course entitled “eBusiness Principles” in my first year of lecturing at the University of Wollongong, and after an initial scurry to find an adequate textbook, …


Process-Evaluation Of Tropospheric Humidity Simulated By General Circulation Models Using Water Vapor Isotopologues: 1. Comparison Between Models And Observations, Camille Risi, David Noone, John Worden, Christian Frankenberg, Gabriele Stiller, Michael Kiefer, Bernd Funke, Kaley Walker, Peter Bernath, Matthias Schneider, Debra Wunch, Vanessa Sherlock, Nicholas M. Deutscher, David W. Griffith, Paul O. Wennberg, Kimberly Strong, Dan Smale, Emmanuel Mahieu, Sabine Barthlott, Frank Hase, Omar Garcia, Justus Notholt, Thorsten Warneke, Geoffrey Toon, David Sayres, Sandrine Bony, Jeonghoon Lee, Derek Brown, Ryu Uemura, Christophe Sturm Mar 2012

Process-Evaluation Of Tropospheric Humidity Simulated By General Circulation Models Using Water Vapor Isotopologues: 1. Comparison Between Models And Observations, Camille Risi, David Noone, John Worden, Christian Frankenberg, Gabriele Stiller, Michael Kiefer, Bernd Funke, Kaley Walker, Peter Bernath, Matthias Schneider, Debra Wunch, Vanessa Sherlock, Nicholas M. Deutscher, David W. Griffith, Paul O. Wennberg, Kimberly Strong, Dan Smale, Emmanuel Mahieu, Sabine Barthlott, Frank Hase, Omar Garcia, Justus Notholt, Thorsten Warneke, Geoffrey Toon, David Sayres, Sandrine Bony, Jeonghoon Lee, Derek Brown, Ryu Uemura, Christophe Sturm

Faculty of Science - Papers (Archive)

[1] The goal of this study is to determine how H2O and HDO measurements in water vapor can be used to detect and diagnose biases in the representation of processes controlling tropospheric humidity in atmospheric general circulation models (GCMs). We analyze a large number of isotopic data sets (four satellite, sixteen ground-based remote-sensing, five surface in situ and three aircraft data sets) that are sensitive to different altitudes throughout the free troposphere. Despite significant differences between data sets, we identify some observed HDO/H2O characteristics that are robust across data sets and that can be used to evaluate models. We evaluate …


The Role Of Streptokinase As A Virulence Determinant Of Streptococcus Pyogenes - Potential For Therapeutic Targeting, Jason D. Mcarthur, Simon M. Cook, Carola Venturini, Mark J. Walker Mar 2012

The Role Of Streptokinase As A Virulence Determinant Of Streptococcus Pyogenes - Potential For Therapeutic Targeting, Jason D. Mcarthur, Simon M. Cook, Carola Venturini, Mark J. Walker

Faculty of Science - Papers (Archive)

Streptococcus pyogenes is a major human pathogen responsible for numerous diseases ranging from uncomplicated skin and throat infections to severe, life threatening invasive disease such as necrotising fasciitis and streptococcal toxic shock syndrome. These severe invasive infections progress rapidly and produce high rates of morbidity and mortality despite the implementation of aggressive treatment plans. The activation of plasminogen and the acquisition of plasmin activity at the bacterial cell surface is critical for the invasive pathogenesis of this organism. To facilitate this process, S. pyogenes secrete streptokinase, a potent plasminogen activating protein. Here, we describe the role of streptokinase in invasive …


Seed Bank Persistence And Climate Change, Mark K. J Ooi Feb 2012

Seed Bank Persistence And Climate Change, Mark K. J Ooi

Faculty of Science - Papers (Archive)

"The strong mechanistic relationship between climatic factors and seed dormancy and germination suggests that forecast climatic changes will significantly affect seed bank persistence. This review focuses on the potential impact of changing temperature, rainfall and fire regimes on the longevity of long-term persistent seed-banks. Currently, there are few studies investigating the mechanistic responses of demographic processes, such as seed-bank dynamics, to forecast climate change. However, from the work that has been published, several key points have been highlighted. First, increased air temperatures will produce significantly higher soil temperatures in open and sparsely vegetated habitats. Some evidence shows that this could …


Sousveillance And The Social Implications Of Point Of View Technologies In The Law Enforcement Sector, Katina Michael, M.G. Michael Feb 2012

Sousveillance And The Social Implications Of Point Of View Technologies In The Law Enforcement Sector, Katina Michael, M.G. Michael

Associate Professor Katina Michael

Policing today has become a high-tech affair; especially in the provision of incident event tracking and reporting systems increasingly being used to provide evidence in a court of law. These in-car video (ICV) and body worn recording systems are said to increase convictions and eliminate false claims made by defendants, providing documentary support to police officers and their associated actions in an incident. But today, new technologies such as smart phones equipped with cameras and global positioning system chipsets can also be found in the hands of the everyday citizen, used to capture everyday happenings and distributed to social networks …


Book Review: Security Risk Management: Building An Information Security Risk Management Program From The Ground Up, Katina Michael Jan 2012

Book Review: Security Risk Management: Building An Information Security Risk Management Program From The Ground Up, Katina Michael

Associate Professor Katina Michael

In an age of outsourcing tasks that are not considered to be a core competency of the business, organisations have often relied on external consultants for matters pertaining to security. In actual fact, most companies could have utilized existing skill-sets in-house to produce a security risk management program, if only they knew what steps to take, and how to go about it all. Evan Wheeler in his book on information security risk management does just that- he equips professionals tasked with security, with the thinking required to create a program that is more preoccupied with the complex strategic-level questions than …


Location Privacy Under Dire Threat As Uberveillance Stalks The Streets, Katina Michael, Roger Clarke Jan 2012

Location Privacy Under Dire Threat As Uberveillance Stalks The Streets, Katina Michael, Roger Clarke

Associate Professor Katina Michael

Location tracking and monitoring applications have proliferated with the arrival of smart phones that are equipped with onboard global positioning system (GPS) chipsets. It is now possible to locate a smart phone user down to 10 metres of accuracy on average. Innovators have been quick to capitalise on this emerging market by introducing novel pedestrian tracking technologies which can denote the geographic path of a mobile user. At the same time there is contention by law enforcement personnel over the need for a warrant process to track an individual in a public space. This paper considers the future of location …


Radiocarbon Bomb Spike Reveals Biological Effects Of Antarctic Climate Change, Laurence J Clarke, Sharon A. Robinson, Quan Hua, David J. Ayre, David Fink Jan 2012

Radiocarbon Bomb Spike Reveals Biological Effects Of Antarctic Climate Change, Laurence J Clarke, Sharon A. Robinson, Quan Hua, David J. Ayre, David Fink

Faculty of Science - Papers (Archive)

The Antarctic has experienced major changes in temperature, wind speed and stratospheric ozone levels during thelast 50 years. However, until recently continental Antarctica appeared to be little impacted by climate warming, thusbiological changes were predicted to be relatively slow. Detecting the biological effects of Antarctic climate changehas been hindered by the paucity of long-term data sets, particularly for organisms that have been exposed to thesechanges throughout their lives. We show that radiocarbon signals are preserved along shoots of the dominant Antarcticmoss flora and use these to determine accurate growth rates over a period of several decades, allowing us toexplore the …


Clinical Dyslipidaemia Is Associated With Changes In The Lipid Composition And Inflammatory Properties Of Apolipoprotein-B-Containing Lipoproteins From Women With Type 2 Diabetes, M Ståhlman, T H. Pham, M Adiels, Todd Mitchell, Stephen J. Blanksby, B Fagerberg, K Ekross, J Boren Jan 2012

Clinical Dyslipidaemia Is Associated With Changes In The Lipid Composition And Inflammatory Properties Of Apolipoprotein-B-Containing Lipoproteins From Women With Type 2 Diabetes, M Ståhlman, T H. Pham, M Adiels, Todd Mitchell, Stephen J. Blanksby, B Fagerberg, K Ekross, J Boren

Faculty of Science - Papers (Archive)

Aims/hypothesis The aim of this study was to use lipidomics to determine if the lipid composition of apolipoprotein-Bcontaining lipoproteins is modified by dyslipidaemia in type 2 diabetes and if any of the identified changes potentially have biological relevance in the pathophysiology of type 2 diabetes.

Methods VLDL and LDL from normolipidaemic and dyslipidaemic type 2 diabetic women and controls were isolated and quantified with HPLC and mass spectrometry. A detailed molecular characterisation of VLDL triacylglycerols (TAG) was also performed using the novel ozone-induced dissociation method, which allowed us to distinguish vaccenic acid (C18:1 n-7) from oleic acid (C18:1 n-9) in …


Optimization Of Colorimetric Det Technique For The In Situ, Two-Dimensional Measurement Of Iron(Ii) Distributions In Sediment Porewaters, William W. Bennett, Peter R. Teasdale, David T. Welsh, Jarad G. Panther, Dianne F. Jolley Jan 2012

Optimization Of Colorimetric Det Technique For The In Situ, Two-Dimensional Measurement Of Iron(Ii) Distributions In Sediment Porewaters, William W. Bennett, Peter R. Teasdale, David T. Welsh, Jarad G. Panther, Dianne F. Jolley

Faculty of Science - Papers (Archive)

No abstract provided.


Coral Reefs And Reef Islands Of The Amirantes Archipelago, Western Indian Ocean, Sarah Hamylton, Tom Spencer, Annelise B. Hagan Jan 2012

Coral Reefs And Reef Islands Of The Amirantes Archipelago, Western Indian Ocean, Sarah Hamylton, Tom Spencer, Annelise B. Hagan

Faculty of Science - Papers (Archive)

No abstract provided.


Inorganic Arsenic And Iron(Ii) Distributions In Sediment Porewaters Investigated By A Combined Dgt - Colourimetric Det Technique, William Bennett, Peter R. Teasdale, David T. Welsh, Jarad Panther, Ryan R. Stewart, Helen L. Price, Dianne F. Jolley Jan 2012

Inorganic Arsenic And Iron(Ii) Distributions In Sediment Porewaters Investigated By A Combined Dgt - Colourimetric Det Technique, William Bennett, Peter R. Teasdale, David T. Welsh, Jarad Panther, Ryan R. Stewart, Helen L. Price, Dianne F. Jolley

Faculty of Science - Papers (Archive)

No abstract provided.


Dye Regeneration And Charge Recombination In Dye-Sensitized Solar Cells With Ferrocene Derivatives As Redox Mediators, Torben Daeneke, Attila J. Mozer, Tae-Hyuk Kwon, Noel W. Duffy, Andrew B. Holmes, Udo Bach, Leone Spiccia Jan 2012

Dye Regeneration And Charge Recombination In Dye-Sensitized Solar Cells With Ferrocene Derivatives As Redox Mediators, Torben Daeneke, Attila J. Mozer, Tae-Hyuk Kwon, Noel W. Duffy, Andrew B. Holmes, Udo Bach, Leone Spiccia

Faculty of Science - Papers (Archive)

Ferrocene compounds are promising redox shuttles for application in dye-sensitized solar cells (DSCs). Chemical modification of the cyclopentadienyl rings is easily achievable affording almost unlimited variation of the redox properties. This allows fine-tuning of the driving force for dye-regeneration and optimization of the energy conversion efficiency of DSCs. Herein, six ferrocene derivatives have been chosen for investigation which cover the large redox potential range of 0.85 V, by virtue of simple alkylation and halogenation of the cyclopentadienyl ring, and enable improved matching of the energy levels of the sensitizer and the electrolyte. Although the focus of this work was to …


Direct Detection Of Additives And Degradation Products From Polymers By Liquid Extraction Surface Analysis Employing Chip-Based Nanospray Mass Spectrometry, Martin Paine, Phillip Barker, Shane A. Maclaughlin, Todd W. Mitchell, Stephen J. Blanksby Jan 2012

Direct Detection Of Additives And Degradation Products From Polymers By Liquid Extraction Surface Analysis Employing Chip-Based Nanospray Mass Spectrometry, Martin Paine, Phillip Barker, Shane A. Maclaughlin, Todd W. Mitchell, Stephen J. Blanksby

Faculty of Science - Papers (Archive)

Rationale: Polymer-based surface coatings in outdoor applications experience accelerated degradation due to exposure to solar radiation, oxygen and atmospheric pollutants. These deleterious agents cause undesirable changes to the polymers aesthetic and mechanical properties reducing its lifetime. The use of antioxidants such as hindered amine light stabilisers (HALS) retard these degradative processes, however, mechanisms for HALS action and polymer degradation are poorly understood. Methods: Detection of the hindered amine light stabiliser (HALS) TINUVIN®123 (bis (1-octyloxy-2,2,6,6-tetramethyl-4-piperidyl) sebacate) and the polymer degradation products directly from a polyester-based coil coating was achieved by liquid extraction surface analysis (LESA) coupled to a triple quadrupole QTRAP® …


Different Radiolabelling Methods Alter The Pharmacokinetic And Biodistribution Properties Of Plasminogen Activator Inhibitor Type 2 (Pai-2) Forms, Marie Ranson, Paula Berghofer, Kara L. Vine, Ivan Greguric, Rachael Shepherd, Andrew Katsifis Jan 2012

Different Radiolabelling Methods Alter The Pharmacokinetic And Biodistribution Properties Of Plasminogen Activator Inhibitor Type 2 (Pai-2) Forms, Marie Ranson, Paula Berghofer, Kara L. Vine, Ivan Greguric, Rachael Shepherd, Andrew Katsifis

Faculty of Science - Papers (Archive)

Introduction: Tumour-associated urokinase plasminogen activator (uPA) is a critical marker of invasion and metastasis, and it is recognised as having strong prognostic relevance as well as being a therapeutic target. The specific uPA inhibitor plasminogen activator inhibitor type-2 (PAI-2, SerpinB2) specifically targets cell bound uPA and is internalised. Furthermore, preclinical studies have established the “proof-of-principle” of uPA-targeting by PAI-2-cytotoxin conjugates in human carcinoma models. However, these studies also suggest that PAI-2 is rapidly cleared via the renal system with low total dose reaching the tumour. In this study, a comparative single photon emission computed tomography (SPECT) and biodistribution (BD) analysis …