Open Access. Powered by Scholars. Published by Universities.®
Large or Food Animal and Equine Medicine Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Life Sciences (510)
- Animal Sciences (474)
- Veterinary Preventive Medicine, Epidemiology, and Public Health (355)
- Meat Science (342)
- Veterinary Infectious Diseases (63)
-
- Other Animal Sciences (52)
- Veterinary Physiology (39)
- Medical Sciences (38)
- Physiology (34)
- Veterinary Toxicology and Pharmacology (34)
- Agriculture (31)
- Endocrinology (31)
- Reproductive and Urinary Physiology (31)
- Diseases (30)
- Neuroscience and Neurobiology (30)
- Other Neuroscience and Neurobiology (30)
- Veterinary Microbiology and Immunobiology (29)
- Veterinary Pathology and Pathobiology (26)
- Dairy Science (25)
- Animal Diseases (19)
- Agricultural Economics (15)
- Genetics and Genomics (15)
- Medical Specialties (15)
- Immunology and Infectious Disease (12)
- Organisms (12)
- Social and Behavioral Sciences (12)
- Veterinary Anatomy (11)
- Institution
-
- University of Nebraska - Lincoln (364)
- University of Kentucky (133)
- Universidad de La Salle (81)
- University of Tennessee, Knoxville (47)
- Kansas State University Libraries (36)
-
- SelectedWorks (24)
- Selected Works (12)
- Iowa State University (11)
- Department of Primary Industries and Regional Development, Western Australia (9)
- University of Arkansas, Fayetteville (9)
- Otterbein University (7)
- Murray State University (6)
- South Dakota State University (4)
- California Polytechnic State University, San Luis Obispo (3)
- Chapman University (3)
- Louisiana State University (3)
- Old Dominion University (3)
- The University of Maine (3)
- University of New Hampshire (3)
- Utah State University (3)
- Augustana College (2)
- Children's Mercy Kansas City (2)
- Embry-Riddle Aeronautical University (2)
- Mississippi State University (2)
- University of Rhode Island (2)
- Chinese Academy of Sciences (1)
- Clemson University (1)
- Seattle Pacific University (1)
- WellBeing International (1)
- West Virginia University (1)
- Keyword
-
- Equine (36)
- Horse (32)
- Horses (30)
- Cattle (24)
- Animals (22)
-
- POSTERS (16)
- Sheep (16)
- Caballos (15)
- Enfermedades en caballos (12)
- PEDV (12)
- Swine (11)
- Equinos (10)
- Inseminación artificial (10)
- Cría de caballos (9)
- Enfermedades en equinos (9)
- Female (9)
- Male (9)
- Humans (8)
- NEWSLETTERS (8)
- Horse Diseases (7)
- KISSPEPTIN (7)
- Kisspeptin (7)
- Pregnancy (7)
- Western Australia (7)
- Bovine (6)
- Calf (6)
- Cows (6)
- Feces (6)
- Leptospirosis (6)
- Pharmacokinetics (6)
- Publication Year
- Publication
-
- Nebraska Beef Cattle Reports (318)
- Maxwell H. Gluck Equine Research Center Faculty Publications (88)
- Medicina Veterinaria (78)
- Kansas Agricultural Experiment Station Research Reports (35)
- Faculty Publications and Other Works -- Large Animal Clinical Sciences (27)
-
- Theses and Dissertations--Veterinary Science (27)
- Brian K Whitlock, PhD, DVM, DACT (19)
- Nebraska Beef Quality Assurance Program (15)
- Veterinary Science Faculty Publications (9)
- Claire B. Andreasen (8)
- Animal Science Publications and Other Works (7)
- Undergraduate Honors Thesis Projects (7)
- Historical Research Bulletins of the Nebraska Agricultural Experiment Station (6)
- Journal of the Department of Agriculture, Western Australia, Series 4 (6)
- School of Veterinary and Biomedical Sciences: Dissertations, Theses, and Student Research (6)
- Doctoral Dissertations (5)
- Masters Theses (5)
- Animal Science Undergraduate Honors Theses (4)
- Charles W. Raker (1920 - 2014) (4)
- Graduate Theses and Dissertations (4)
- Honors College Theses (4)
- Animal and Food Sciences Faculty Publications (3)
- Electronic Theses and Dissertations (3)
- Maestría en Ciencias Veterinarias (3)
- Nebraska Agricultural Experiment Station: Historical Circulars (3)
- Pharmacy Faculty Articles and Research (3)
- Reza Seddighi (3)
- Veterinary and Biomedical Sciences -- Department Information and History (3)
- Agriculture reports (2)
- Animal Science (2)
Articles 1 - 30 of 780
Full-Text Articles in Large or Food Animal and Equine Medicine
Extending Knowledge On Biosecurity In Small-Scale And Backyard Systems In The United States, Juliette Di Francesco, Amber Itle, Craig Mcconnel, Ragan Adams, Roselle Busch, Richard Van Vleck Pereira, Terry W. Lehenbauer, Beatriz Martínez-López, Alda F. A. Pires
Extending Knowledge On Biosecurity In Small-Scale And Backyard Systems In The United States, Juliette Di Francesco, Amber Itle, Craig Mcconnel, Ragan Adams, Roselle Busch, Richard Van Vleck Pereira, Terry W. Lehenbauer, Beatriz Martínez-López, Alda F. A. Pires
The Journal of Extension
The number of small-scale and backyard operations has increased in the United States during the past decade, but there is currently a lack of outreach efforts and readily-available educational materials targeting these farming systems. We developed a webinar series on biosecurity to provide training for small-scale and backyard producers, and training tools that can be used by local veterinarians and extension educators to disseminate knowledge and consistent recommendations more effectively. Fewer people attended the webinars than registered, suggesting a gap between interest in biosecurity and commitment to the topic. Participants in the webinar series reported a high level of satisfaction …
Ethyl Pyruvate Failed To Reduce Pro-Inflammatory Cytokines Release Following In Vitro Stimulation In Dairy Calves' Whole Blood., Vincent Dore
Doctoral Dissertations
Recent developments in sepsis treatment showed that control of the late mediator of inflammation, High Mobility Box group-1 (HMGB1), improves survival in animal models of endotoxemia. Ethyl pyruvate is a small-molecule inhibitor that has been shown to reduce the systemic release of HMGB1 during experimental treatment of systemic inflammation in different species. The objectives of this body of work were 1) to explore ethyl pyruvate's ability to modulate early pro-inflammatory cytokines production and immune effector function in treated calves, 2) to evaluate the safety of an administration of ethyl pyruvate infusion in neonatal calves, and 3) to explore ethyl pyruvate's …
Impact Of A Study Abroad Course In Helping Undergraduate Students Affirm Their Career Aspirations To Become Veterinarians: A Qualitative Inquiry, Jose M. Uscanga, M. Craig Edwards, J. Shane Robinson, Rob Terry Jr., Udaya Desilva
Impact Of A Study Abroad Course In Helping Undergraduate Students Affirm Their Career Aspirations To Become Veterinarians: A Qualitative Inquiry, Jose M. Uscanga, M. Craig Edwards, J. Shane Robinson, Rob Terry Jr., Udaya Desilva
Journal of International Agricultural and Extension Education
Twenty-five students who participated in a study abroad course tailored to veterinary medicine during the summer of 2019 were the study’s sources of data. Using photovoice and phenomenology research methods, we sought to explore, understand, and interpret the impact of a study abroad course on pre-vet students’ views regarding veterinary medicine and their aspirations to become veterinarians. Students perceived that veterinary medicine in Mexico was structured differently from the U.S. approach and the nation’s socioeconomic and agroclimatology conditions impacted the delivery of veterinary care and affected the work settings and practice of veterinarians. They not only discerned the uniqueness of …
Cryptosporidiosis In An Alpaca Cria Secondary To Prolongedantimicrobial Administration, Heidi M. Wyrosdick, Caroline Griffin, John J. Schaefer, Joseph Smith
Cryptosporidiosis In An Alpaca Cria Secondary To Prolongedantimicrobial Administration, Heidi M. Wyrosdick, Caroline Griffin, John J. Schaefer, Joseph Smith
Faculty Publications and Other Works -- Large Animal Clinical Sciences
No abstract provided.
Devoting Continuous Efforts To Innovations And Development Of Ruminant Livestock Life-Cycle Nutrition Program, Zhixiong He, Zhaomin Hu, Hongsheng Wang, Jinzhen Jiao, Xuefeng Han, Yong Liu, Shaoxun Tang, Chuanshe Zhou, Min Wang, Zhiliang Tan
Devoting Continuous Efforts To Innovations And Development Of Ruminant Livestock Life-Cycle Nutrition Program, Zhixiong He, Zhaomin Hu, Hongsheng Wang, Jinzhen Jiao, Xuefeng Han, Yong Liu, Shaoxun Tang, Chuanshe Zhou, Min Wang, Zhiliang Tan
Bulletin of Chinese Academy of Sciences (Chinese Version)
Ruminant livestock such as cattle and sheep can provide high-quality beef, mutton and milk, which are high-quality protein sources meeting the increasingly diverse food consumption needs for human being. Developing high-quality herbivorous animal husbandry is a concrete practice of practicing the “Greater Food” approach. The precise supply of forages and concentrates meeting the requirements of all nutrients in the whole life cycle is vital for cost saving and efficiency increasing of ruminant livestock industry, which is an important way to high-quality development. The whole life cycle nutrition is developed on the basis of traditional ruminant nutrition and new technologies made …
Delayed Urethral Obstruction After Migration Of A Ballistic Pellet In An Alpine Wether, Joseph Smith
Delayed Urethral Obstruction After Migration Of A Ballistic Pellet In An Alpine Wether, Joseph Smith
Faculty Publications and Other Works -- Large Animal Clinical Sciences
A one-year-old alpine wether was presented for emergency evaluation of stranguria. Diagnostics identified a moderately distended bladder and mild dehydration. Preliminary lateral radiographs identified two metallic structures consistent with projectile pellets in the pelvic and perineal regions and no evidence of radiopaque uroliths. A tube cystostomy was performed, and a contrast urethrogram revealed one of the pellets in the perineal region was in proximity to the urethral obstruction. Subsequent radiography and ultrasound identified the pellet as being within the lumen of the urethra. Examination of the trichotomized skin revealed two scars, including a scar over the paralumbar fossa in the …
Identifying Barriers To Data Use On U.S. Beef Cow-Calf Operations And Developing Solutions To Improve Cow-Calf Record-Keeping, William Isaac Jumper
Identifying Barriers To Data Use On U.S. Beef Cow-Calf Operations And Developing Solutions To Improve Cow-Calf Record-Keeping, William Isaac Jumper
Theses and Dissertations
Cattle health and production records (CHPR) are data collected by cattle producers and veterinarians in the form of measurements, observations, counts of events over time, and physiologic attributes that describe individual and group-level health and production. These data are useful to both veterinarians and cattle producers for making evidence-based decisions on cow-calf operations. Currently, there are no uniform, industry-wide methods of capturing and recording CHPR in the U.S. cow-calf industry. Although many cow-calf producers in the U.S. are thought to collect some form of CHPR, it is believed that relatively few are doing so in an electronic manner that facilitates …
Pharmacokinetics Of Single Feeding Of Cannabidiol In Cattle: A Pilot Study, Haley Cornette
Pharmacokinetics Of Single Feeding Of Cannabidiol In Cattle: A Pilot Study, Haley Cornette
Honors College Theses
Cannabidiol (CBD) is a substance that has been used in complementary medicine for many years. However, modern medicine has little knowledge of how this substance is utilized and metabolized in ruminant animals. Regulations on quality assurance and use in animals are lacking, and CBD supplementation in livestock is not approved. If CBD supplements can be shown to be safe and effective, detection in the animal will be important for determining regulation of use. A withdrawal period can then be established to allow time for deterioration of product to safe levels before livestock products enter human markets. This study sought to …
Pharmacokinetics Of Intramuscular Maropitant In Pigs (Sus Scrofa Domesticus), Joseph Smith, Jessica E. Gebert, Lisa S. Ebner, Kailee O. Bennett, Rebecca J. Collins, Chiara E. Hampton, Stephanie A. Kleine, Pierre-Yves Mulon, Christopher K. Smith, Reza Seddighi, Genevieve Bussieres, Jonathan P. Mochel, Healther K. Knych
Pharmacokinetics Of Intramuscular Maropitant In Pigs (Sus Scrofa Domesticus), Joseph Smith, Jessica E. Gebert, Lisa S. Ebner, Kailee O. Bennett, Rebecca J. Collins, Chiara E. Hampton, Stephanie A. Kleine, Pierre-Yves Mulon, Christopher K. Smith, Reza Seddighi, Genevieve Bussieres, Jonathan P. Mochel, Healther K. Knych
Faculty Publications and Other Works -- Large Animal Clinical Sciences
Pigs are at risk of vomiting from medical conditions as well as the emetic side effects of drugs administered for peri-operative manipulations, but there is a lack of pharmacokinetic data for potential anti-emetic therapies, such as maropitant, in this species. The main objective of this study was to estimate plasma pharmacokinetic parameters for maropitant in pigs after a single intramuscular (IM) administration dosed at 1.0 mg/ kg. A secondary objective was to estimate pilot pharmacokinetic parameters in pigs after oral (PO) administration at 2.0 mg/kg. Maropitant was administered to six commercial pigs at a dose of 1.0 mg/kg IM. Plasma …
First Bovine Vaccine To Prevent Human Schistosomiasis - A Cluster Randomised Phase 3 Clinical Trial, Allen G. Ross, Donald A. Harn, Delia Chy, Marianette Inobaya, Jerric R. Guevarra, Lisa Shollenberger, Yuesheng Li, Donald P. Mcmanus, Darren J. Gray, Gail M. Williams
First Bovine Vaccine To Prevent Human Schistosomiasis - A Cluster Randomised Phase 3 Clinical Trial, Allen G. Ross, Donald A. Harn, Delia Chy, Marianette Inobaya, Jerric R. Guevarra, Lisa Shollenberger, Yuesheng Li, Donald P. Mcmanus, Darren J. Gray, Gail M. Williams
Biological Sciences Faculty Publications
Objective
Schistosomiasis is a neglected tropical parasitic disease caused by blood flukes of the genus Schistosoma. Schistosoma japonicum is zoonotic in China, the Philippines, and Indonesia, with bovines acting as major reservoirs of human infection. The primary objective of the trial was to examine the impact of a combination of human mass chemotherapy, snail control through mollusciciding, and SjCTPI bovine vaccination on the rate of human infection.
Methods
A 5-year phase IIIa cluster randomized control trial was conducted among 18 schistosomiasis-endemic villages comprising 18,221 residents in Northern Samar, The Philippines.
Results
Overall, bovine vaccination resulted in a statistically significant decrease …
Whole Genome Sequencing For Identification Of Putative Causative Alleles For Hemochromatosis In Horses, Anna M. Rauber-Ramos
Whole Genome Sequencing For Identification Of Putative Causative Alleles For Hemochromatosis In Horses, Anna M. Rauber-Ramos
Schultz-Werth Award Papers
Hemochromatosis is liver disorder in which excess iron is stored in the liver, leading to iron overload and extensive liver damage that can prove fatal. Based on human precedence, a genetic cause for idiopathic hemochromatosis in horses is suspected. Two horses with hemochromatosis were whole genome sequenced, with variants in candidate genes prioritized in analyses of potential pathogenicity. No clear putative variants were found to be present in both horses, suggesting an etiology more complex than the initially suspected Mendelian inheritance. A heterozygous nonsense mutation in STEAP3 metalloreductase (STEAP3) was identified as a potential contributor to hemochromatosis in one of …
Equine Fecal Microbiota Response To Short Term Antibiotic Administration, Jordan Lacey Parker
Equine Fecal Microbiota Response To Short Term Antibiotic Administration, Jordan Lacey Parker
Theses and Dissertations--Veterinary Science
Though generally regarded as safe, research continues to demonstrate negative side effects of antibiotic administration on the gastrointestinal (GIT) microbiota across species. In horses, antibiotic associated diarrhea (AAD) is a life-threatening side effect linked to the GIT microbiota. This study tested the hypothesis that short term antibiotic administration to healthy horses would negatively impact the fecal microbiota as measured by their ability to digest nutrients and produce short chain fatty acids (SCFAs). Twenty-four horses were assigned to one of four treatments: control (CO); potassium penicillin/gentamicin sulfate (KPG); ceftiofur crystalline free acid (EX); trimethoprim/sulfamethoxazole (SMZ); and treated for 4 days. Fecal …
Livestock Cattle As A Predictor Of Schistosomiasis Transmission In Nigeria, Oyetunde T. Oyeyemi, Oluyemi A. Okunlola, Zhiqiang Fu, Yang Hong, Jun-Hu Chen, Lisa M. Shollenberger
Livestock Cattle As A Predictor Of Schistosomiasis Transmission In Nigeria, Oyetunde T. Oyeyemi, Oluyemi A. Okunlola, Zhiqiang Fu, Yang Hong, Jun-Hu Chen, Lisa M. Shollenberger
Biological Sciences Faculty Publications
Livestock cattle have been widely linked to schistosomiasis epidemiology, but little is known about its contribution to schistosomiasis transmission in Nigeria. The aim of this study is to examine the association between prevalence of schistosomiasis and livestock cattle index in Nigeria. The study's data came from three sources: the demographic and health survey (DHS), the malaria indicators survey (MIS), and the expanded special project for the eradication of neglected tropical diseases (ESPEN). Analysis of variance, correlation, and logistic regression were used to evaluate the mean difference in schistosomiasis prevalence across geopolitical zones, the relationship between schistosomiasis prevalence and livestock cattle, …
Effects Of High-Speed Training On Messenger Rna Expression In Two-Year-Old Thoroughbred Racehorses, Mackenzie Grace Johnson
Effects Of High-Speed Training On Messenger Rna Expression In Two-Year-Old Thoroughbred Racehorses, Mackenzie Grace Johnson
Theses and Dissertations--Veterinary Science
Accumulating high-speed exercise has been identified as a significant risk factor for catastrophic injuries in racing Thoroughbreds. Injuries, regardless of severity, are a main cause of withdrawal from the racing industry, raising animal welfare concerns and resulting in significant economic losses. While most of the current literature focuses on catastrophic injuries incurred during racing rather than training, the present study aims to help fill this gap as well as discuss the associated risk factors. The evaluation of messenger RNA (mRNA) expression changes provides an efficient and straightforward approach to identifying horses at risk for catastrophic injury. While alternative injury risk …
Rumen-Protected Methionine Supplementation Improves Lactation, Oxidative Status, And Immune Response During A Subclinical Mastitis Challenge In Lactating Dairy Cows., Anita Paz Lopez
Electronic Theses and Dissertations
Mastitis is a significant problem in the dairy industry, posing numerous challenges for dairy farmers worldwide. Mastitis refers to the inflammation of the mammary gland, primarily caused by bacterial infections. This condition affects the health and well-being of dairy cows and has severe economic implications for farmers and overall dairy production. The prevalence of mastitis substantially threatens milk quality, productivity, and profitability, making it a top concern in the dairy industry. Preventing mastitis in cows is crucial for maintaining the herd's health and ensuring highquality milk production. Nutritional strategies have recently gained greater attention due to a direct impact on …
A Single-Cell Atlas Of Bovine Skeletal Muscle Reveals Mechanisms Regulating Intramuscular Adipogenesis And Fibrogenesis, Leshan Wang, Peidong Gao, Chaoyag Li, Qianglin Liu, Zeyang Yao, Yuxia Li, Xujia Zhang, Jiangwen Sun, Constantine Simintiras, Matthew Welborn, Kenneth Mcmillin, Stephanie Oprescu, Shihuan Kuang, Xing Fu
A Single-Cell Atlas Of Bovine Skeletal Muscle Reveals Mechanisms Regulating Intramuscular Adipogenesis And Fibrogenesis, Leshan Wang, Peidong Gao, Chaoyag Li, Qianglin Liu, Zeyang Yao, Yuxia Li, Xujia Zhang, Jiangwen Sun, Constantine Simintiras, Matthew Welborn, Kenneth Mcmillin, Stephanie Oprescu, Shihuan Kuang, Xing Fu
Computer Science Faculty Publications
Background: Intramuscular fat (IMF) and intramuscular connective tissue (IMC) are often seen in human myopathies and are central to beef quality. The mechanisms regulating their accumulation remain poorly understood. Here, we explored the possibility of using beef cattle as a novel model for mechanistic studies of intramuscular adipogenesis and fibrogenesis.
Methods: Skeletal muscle single-cell RNAseq was performed on three cattle breeds, including Wagyu (high IMF), Brahman (abundant IMC but scarce IMF), and Wagyu/Brahman cross. Sophisticated bioinformatics analyses, including clustering analysis, gene set enrichment analyses, gene regulatory network construction, RNA velocity, pseudotime analysis, and cell-cell communication analysis, were performed to elucidate …
Pharmacokinetics Of Esomeprazole In Goats (Capra Aegagrus Hircus) After Intravenous And Subcutaneous Administration, Rachel L. Fladung, Joseph Smith, Melissa Hines, Windy Soto-Gonzalez, Bryanna Fayne, Rebecca Rahn, Olivia Escher, Lainey Harvill, Joan Bergman, Jessica Garcia, Amanda Kreuder
Pharmacokinetics Of Esomeprazole In Goats (Capra Aegagrus Hircus) After Intravenous And Subcutaneous Administration, Rachel L. Fladung, Joseph Smith, Melissa Hines, Windy Soto-Gonzalez, Bryanna Fayne, Rebecca Rahn, Olivia Escher, Lainey Harvill, Joan Bergman, Jessica Garcia, Amanda Kreuder
Faculty Publications and Other Works -- Large Animal Clinical Sciences
Background: Stressed and hospitalized goats are at risk of developing abomasal (gastric) ulceration, but there is a paucity of pharmacokinetic studies for proton pump inhibiting drugs, such as, esomeprazole in goats.
Objectives: The objectives for this study were to estimate plasma pharmacokinetic parameters for esomeprazole in adult goats after intravenous (IV) and subcutaneous (SQ) administration. A secondary objective was to describe the plasma kinetics of the metabolite esomeprazole sulfone after IV and SC administration in goats.
Materials and methods: Esomeprazole was administered to 5 adult goats in a crossover study at doses of 1 mg/kg IV or 2 mg/kg SC. …
Equine Kinesiology Tape Application To Equine Hock Joints: Impact On Lameness And Movement Evaluation, Kiara Jones
Equine Kinesiology Tape Application To Equine Hock Joints: Impact On Lameness And Movement Evaluation, Kiara Jones
Honors College Theses
Discomfort in the hocks of horses can cause lameness, resulting in poor performance. Diagnosis by veterinarians typically includes evaluating movement or use of ultrasound or radiography to evaluate tendons, ligaments, or bones. Treatment methods and times vary depending on diagnosis, but often include joint injections, medications, and stall rest. Treatments can be costly both financially and regarding time off from practice or competition. Alternative practices such as using equine kinesiology tape to support joints may improve comfort and movement for lower cost. The objective of this project was to evaluate the ease of use and effects of equine kinesiology tape …
Seroprevalence And Titer Concentration Testing For Leptospirosis In Equine, Ashley Himmelsbaugh
Seroprevalence And Titer Concentration Testing For Leptospirosis In Equine, Ashley Himmelsbaugh
Honors College Theses
The most common best management practice used to combat diseases in horses is vaccination, which can decrease the incidence or severity of illness. However, the duration of immunity will vary for each vaccination and must be considered for revaccination purposes. Titer concentration, which evaluates antibodies in the blood, may be a helpful way of determining how long an animal has immunity to a disease. Leptospirosis, a zoonotic, bacterial disease, can result in uveitis, potentially leading to blindness, and abortion in mares. One serovar, Leptospirosis pomona (L. pomona), is associated with most cases of clinical disease in horses in North America. …
Isolation Of Drug-Sensitive Eimeria Species From Wild Turkey Feces And Development Of A Model Bioshuttle Program For Eimeria Meleagrimitis For Domestic Turkeys, Maria Carolina Trujillo Peralta
Isolation Of Drug-Sensitive Eimeria Species From Wild Turkey Feces And Development Of A Model Bioshuttle Program For Eimeria Meleagrimitis For Domestic Turkeys, Maria Carolina Trujillo Peralta
Graduate Theses and Dissertations
The objective of this thesis was to determine the anticoccidial profile of Eimeria spp. derived from wild turkeys. These drug-sensitive Eimeria spp. have potential to be used as vaccine candidates to control coccidiosis in commercial turkeys. Chapter two consists of a brief literature review focused on coccidiosis in turkeys. Chapter three addresses the methodologies utilized to isolate, recover, and speciate Eimeria recovered from wild turkey feces in the eastern two-thirds of the United States. From this, we successfully obtained single oocyst-derived stocks for E. meleagrimitis, E. dispersa, E. meleagridis, E. gallopavonis, and E. adenoeides. Chapter four describes the experiment conducted …
Gabapentin, A Human Therapeutic Medication And An Environmental Substance Transferring At Trace Levels To Horses: A Case Report., Kimberly Brewer, Jacob Machin, George Maylin, Clara Fenger, Abelardo Morales-Briceño, Thomas Tobin
Gabapentin, A Human Therapeutic Medication And An Environmental Substance Transferring At Trace Levels To Horses: A Case Report., Kimberly Brewer, Jacob Machin, George Maylin, Clara Fenger, Abelardo Morales-Briceño, Thomas Tobin
Maxwell H. Gluck Equine Research Center Faculty Publications
Gabapentin, 1-(Aminomethyl)cyclohexaneacetic acid, MW 171.240, is a frequently prescribed high dose human medication that is also used recreationally. Gabapentin is orally absorbed; the dose can be 3,000 mg/day and it is excreted essentially unchanged in urine. Gabapentin is stable in the environment and routinely detected in urban wastewater. Gabapentin randomly transfers from humans to racing horses and is at times detected at pharmacologically ineffective / trace level concentrations in equine plasma and urine. In Ohio racing between January 2019 and July 2020,18 Gabapentin identifications, all less than 2 ng/ml in plasma, were reported. These identifications were ongoing because the horsemen …
Pharmacokinetics Of Butorphanol Following Intravenous And Intramuscular Administration In Donkeys: A Preliminary Study, Lisa S. Ebner, Odette O, Bradley Simon, Ignacio Lizarraga, Joseph Smith, Sherry Cox
Pharmacokinetics Of Butorphanol Following Intravenous And Intramuscular Administration In Donkeys: A Preliminary Study, Lisa S. Ebner, Odette O, Bradley Simon, Ignacio Lizarraga, Joseph Smith, Sherry Cox
Faculty Publications and Other Works -- Large Animal Clinical Sciences
The pharmacokinetics of butorphanol after intravenous (IVB) and intramuscular (IMB) administration in donkeys were determined in this preliminary study. Healthy male gelded donkeys (n = 5), aged 6–12 years old, were administered 0.1 mg/kg butorphanol IV or IM in a randomized, crossover design. Blood samples were obtained at predetermined intervals for 24 h (IVB) and 48 h (IMB) after administration. Plasma butorphanol concentrations were determined by high performance liquid chromatography and pharmacokinetic parameters were calculated. Following IVB administration, mean (± SE) apparent volume of distribution, elimination half-life, total body clearance, and area under the plasma concentration time curve from …
Understanding The Causative Agent, Pathophysiology And Management Of The Kentucky Mare Reproductive Loss Syndrome And Related Syndromes, Thomas Tobin, Gabriel Volpato, Navid Yousefi-Mashouf, Kimberly Brewer
Understanding The Causative Agent, Pathophysiology And Management Of The Kentucky Mare Reproductive Loss Syndrome And Related Syndromes, Thomas Tobin, Gabriel Volpato, Navid Yousefi-Mashouf, Kimberly Brewer
Maxwell H. Gluck Equine Research Center Faculty Presentations
No abstract provided.
Synthesis And Characterization Of D5-Barbarin For Use In Barbarin-Related Research, Sucheta Kudrimoti, Jacob Machin, Adedamola S. Arojojoye, Samuel G. Awuah, Rodney Eisenberg, Clara Fenger, George Maylin, Andreas F. Lehner, Thomas Tobin
Synthesis And Characterization Of D5-Barbarin For Use In Barbarin-Related Research, Sucheta Kudrimoti, Jacob Machin, Adedamola S. Arojojoye, Samuel G. Awuah, Rodney Eisenberg, Clara Fenger, George Maylin, Andreas F. Lehner, Thomas Tobin
Maxwell H. Gluck Equine Research Center Faculty Publications
Based on structural similarities and equine administration experiments, Barbarin, 5-phenyl-2-oxazolidinethione from Brassicaceae plants, is a possible source of equine urinary identifications of aminorex, (R,S)-5-phenyl-4,5-dihydro-1,3-oxazol-2-amine, an amphetamine-related US Drug Enforcement Administration (DEA) controlled substance considered illegal in sport horses. We now report the synthesis and certification of d5-barbarin to facilitate research on the relationship between plant barbarin and such aminorex identifications. D5-barbarin synthesis commenced with production of d5-2-oxo-2-phenylacetaldehyde oxime (d5-oxime) from d5-acetophenone via butylnitrite in an ethoxide/ethanol solution. This d5-oxime was then reduced with lithium aluminum …
Ex Vivo Biomechanical Comparison Of A Novel Compression Screw Fastener And Traditional Ao Cortical Bone Screw For Fixation Of A Simulated Slab Fracture In The Equine Third Carpal Bone, Allison Salinger
Theses and Dissertations
Frontal plane slab fractures account for the majority of third carpal bone (C3) fractures in performance horses. Treatment is stabilization with an AO cortical screw. Complications are fragment splitting, fragment spinning, and irritation of dorsal soft tissue structures. A novel, headless, cannulated screw with interlocking threads (the Headless Compression Screw Fastener, HCSF) has been developed to resist multidirectional forces. Simulated C3 slab fractures were created in nine paired equine carpi. HCSF or AO cortical screws were loaded in shear to failure. Stiffness, maximum load to failure, and yield load was assessed in linear mixed models. No significant difference was detected …
Sporadic Worldwide “Clusters” Of Feed Driven Zilpaterol Identifications In Racing Horses: A Review And Analysis, Jacob Machin, Kimberly Brewer, Abelardo Morales Briceno, Clara Fenger, George Maylin, Thomas Tobin
Sporadic Worldwide “Clusters” Of Feed Driven Zilpaterol Identifications In Racing Horses: A Review And Analysis, Jacob Machin, Kimberly Brewer, Abelardo Morales Briceno, Clara Fenger, George Maylin, Thomas Tobin
Maxwell H. Gluck Equine Research Center Faculty Publications
Zilpaterol is a β2-adrenergic agonist medication approved in certain countries as a cattle feed additive to improve carcass quality. Trace amounts of Zilpaterol can transfer to horse feed, yielding equine urinary “identifications” of Zilpaterol. These “identifications” occur because Zilpaterol is highly bioavailable in horses, resistant to biotransformation and excreted as unchanged Zilpaterol in urine, where it has a 5 day or so terminal half-life.
In horses, urinary steady-state concentrations are reached 25 days (5 half-lives) after exposure to contaminated feed. Zilpaterol readily presents in horse urine, yielding clusters of feed related Zilpaterol identifications in racehorses. The first cluster, April …
Failure Of Passive Transfer In Camel Calves: 4 Cases (2010-2019), Amanda James, Joseph Smith, Julie Sheldon, Ricardo Videla
Failure Of Passive Transfer In Camel Calves: 4 Cases (2010-2019), Amanda James, Joseph Smith, Julie Sheldon, Ricardo Videla
Faculty Publications and Other Works -- Large Animal Clinical Sciences
Failure of passive transfer is a management concern for all ruminant species, but is not well described in the literature for camel calves. This case series presents four camel calves (Camelus dromedarius and Camelus bactrianus) referred to a North American veterinary teaching hospital for diagnosis and management of failure of passive transfer. Diagnostics utilized included hematology, serum biochemistry, and immunologic methods as described for crias. Management included antimicrobial, anti-inflammatory, and plasma transfusion therapies. Three of the four calves survived to discharge, and common diagnostic practices such as evaluation of total solids, total protein, immunoglobulin G, and sodium sulfite appear to …
Intra-Articular Buprenorphine In Horses, Gabriel Castro-Cuellar Dr
Intra-Articular Buprenorphine In Horses, Gabriel Castro-Cuellar Dr
LSU Master's Theses
Opioid drugs have the potential of provide local analgesia in inflamed joints. To date, morphine is the only opioid that has been tested for intra-articular (IA) administration in horses. Having an alternative drug, other than morphine, could widen the therapeutic options, particularly in cases of drug shortages or inaccessibility to specific drugs. The work presented in this dissertation reports the cytotoxic effects of buprenorphine on cultured equine chondrocytes, and the pharmacokinetic, pharmacodynamic and analgesic effects, of IA administered buprenorphine in horses with experimentally induced synovitis.
To evaluate the potential cytotoxic effects on equine cartilage, chondrocytes were obtained from normal equine …
Miniature Companion Pig Sedation And Anesthesia, Joseph Smith, Reza Seddighi
Miniature Companion Pig Sedation And Anesthesia, Joseph Smith, Reza Seddighi
Faculty Publications and Other Works -- Large Animal Clinical Sciences
- Miniature companion pigs (MCP) are increasing in popularity, and as such, there is an increased need for veterinarians trained in sedation and anesthesia for the species.
- MCPs have several species-specific qualities that can complicate injectable drug administration and create challenges for inhalational anesthesia (eg, with endotracheal intubation).
- General anesthetic complications, such as hypothermia and hypotension, are commonly described in miniature companion pigs, so monitoring of vital parameters during anesthetic procedures and recovery is crucial.
Severe Mandibular Osteomyelitis And Exfoliation Of A Mandibular Canine Tooth In A Vietnamese Potbellied Pig, Joseph Smith, Caroline Griffin, Phil Jones, Brenda Mulherin, Silke Hecht
Severe Mandibular Osteomyelitis And Exfoliation Of A Mandibular Canine Tooth In A Vietnamese Potbellied Pig, Joseph Smith, Caroline Griffin, Phil Jones, Brenda Mulherin, Silke Hecht
Faculty Publications and Other Works -- Large Animal Clinical Sciences
∙Preventative care of miniature companion pigs should include regular oral examinations and incorporate routine tusk maintenance.
∙Severe dental disease can lead to significant sequelae, including osteomyelitis leading to loss of mandibular structural integrity.
∙Diagnostic imaging is a useful tool for assessment of dental disease in miniature companion pigs.