Large or Food Animal and Equine Medicine Commons^™

Pharmacokinetics Of Famotidine In Goats After Intravenous Administration, Olivia Escher, Joseph Smith, Kamryn Christopher, Bryan Hogan, Lainey Harvill, Makenna Hopson, Sherry Cox

Faculty Publications and Other Works -- Large Animal Clinical Sciences

No abstract provided.

Effects Of Strong Oxidants Present In Acer Spp. On Hemolysis Methemoglobin Production In Equine Erythrocytes, Gabrielle Mcgeorge, Jeffrey Lehman

Undergraduate Honors Thesis Projects

Maple toxicosis is a deadly condition affecting equines after they have ingested wilted leaves of the genus Acer (i.e., maple species). It is characterized by hemolytic anemia and methemoglobinemia. Although the toxins responsible for causing toxicosis have not been identified, they are thought to be strong oxidants. The objective of this study is to determine the effect of eight compounds (galloyl derivatives) found in Acer spp. on hemolysis and methemoglobin production in bioassays with equine erythrocytes. Seven of the compounds are known constituents of Acer spp. that are commercially available. One of the compounds--acertannin--was isolated and characterized from leaf extracts …

Kisspeptin Modulates Luteinizing Hormone Release And Ovarian Follicular Dynamics In Pre-Pubertal And Adult Murrah Buffaloes, Vishalkumar Pottapenjera, Srinivasa R. Rajanala, Chandrasekhar Reddy, Arunakumari Gangineni, Kiran Avula, Sandeep K. Bejjanki, Sriravali Sathagopam, Surabhi Kesharwani, Sathya Velmurugan

Pharmacology and Nutritional Sciences Faculty Publications

Kisspeptin is a neuropeptide that governs the reproductive axis upstream to GnRH. We wanted to study whether kisspeptin modulates plasma LH and FSH levels and ovarian follicular dynamics in buffaloes and whether kisspeptin can be used for fixed time artificial insemination (FTAI). We carried out these studies in comparison with buserelin, a potent GnRH agonist. Kisspeptin dose-dependently increased plasma LH levels. However, the kisspeptin-induced increase in LH was short-lived as the peak reached in 15–30 min returned to basal values by 1–2 h. The kisspeptin-induced increase in LH level was less compared to buserelin-induced increase in LH level which sustained …

An Epidemiologic Study Of Antimicrobial Resistance Of Staphylococcus Species Isolated From Equine Samples Submitted To A Diagnostic Laboratory, Ronita Adams, Jackie Smith, Stephan Locke, Erica Phillips, Erdal Erol, Craig N. Carter, Agricola Odoi

Veterinary Science Faculty Publications

Background

Antimicrobial resistance limits traditional treatment options and increases costs. It is therefore important to estimate the magnitude of the problem so as to provide empirical data to guide control efforts. The aim of this study was to investigate the burden and patterns of antimicrobial resistance (AMR) among equine Staphylococcus samples submitted to the University of Kentucky Veterinary Diagnostic Laboratory (UKVDL) from 1993 to 2009. Retrospective data of 1711 equine Staphylococcus samples submitted to the UKVDL during the time period 1993 to 2009 were included in the study. Antimicrobial susceptibility testing, that included 16 drugs, were performed using cultures followed …

Development Of A Novel Ex Vivo Equine Corneal Model, Todd L. Marlo, Elizabeth A. Giuliano, Ajay Sharma, Rajiv R. Mohan

Pharmacy Faculty Articles and Research

Objective

To develop an ex vivo equine corneal organ culture model. Specifically, to assess the equine cornea's extracellular matrix and cellularity after 7 days using two different culture techniques: either (i) immersion system or (ii) air/liquid interface system, to determine the best ex vivo equine corneal model.

Animals Studied

Fourteen healthy equine corneas of various breeds.

Procedures

Equine corneas with 2 mm of perilimbal sclera were freshly harvested from 7 horses undergoing humane euthanasia. One corneal–scleral ring (CSR) from each horse was randomly placed in the (i) immersion condition organ culture system (IC), with the contralateral CSR being placed in …

Therapeutic Neonatal Hepatic Gene Therapy In Mucopolysaccharidosis Vii Dogs, Katherine Parker Ponder, John R. Melniczek, Lingfei Xu, Margaret A. Weil, Thomas M. O'Malley, Patricia A. O'Donnell, Van W. Knox, Gustavo D. Aguirre, Hamutal Mazrier, N Matthew Ellinwood, Margaret M. Sleeper, Albert M. Maguire, Susan W. Volk, Robert L. Mango, Jean Zweigle, John H. Wolfe, Mark E. Haskins

Gustavo D. Aguirre, VMD, PhD

Dogs with mucopolysaccharidosis VII (MPS VII) were injected intravenously at 2–3 days of age with a retroviral vector (RV) expressing canine β-glucuronidase (cGUSB). Five animals received RV alone, and two dogs received hepatocyte growth factor (HGF) before RV in an attempt to increase transduction efficiency. Transduced hepatocytes expanded clonally during normal liver growth and secreted enzyme with mannose 6-phosphate. Serum GUSB activity was stable for up to 14 months at normal levels for the RV-treated dogs, and for 17 months at 67-fold normal for the HGF/RV-treated dog. GUSB activity in other organs was 1.5–60% of normal at 6 months for …

Trauma Craneoencefálico En Equinos, Ana Cristina Convit

Medicina Veterinaria

No abstract provided.

Beneficios Y Ventajas De La Inseminación Artificial Utilizando Semen Congelado En Programas De Reproducción En Equinos, Pedro Felipe Mesa Guerra

Medicina Veterinaria

No abstract provided.

Estudio Retrospectivo De Caballos Con Síndrome De Abdomen Agudo Diagnosticados Con Desplazamiento De Colon Dorsal Derecho En El Centro De Veterinaria Y Zootecnia De La Universidad Ces Durante El Período 2005 - 2013, María Camila Maldonado Vera

Medicina Veterinaria

El estudio retrospectivo pretende dar una descripción acerca de los datos históricos de pacientes equinos diagnosticados con desplazamiento de colon dorsal derecho en el Centro de Veterinaria y Zootecnia de la Universidad CES; esto con el fin de caracterizar los signos clínicos más comúnmente asociados a esta patología, resultados del examen físico, hallazgos en las ayudas diagnósticas y exámenes de laboratorio, mortalidad pre y postquirúrgica, así como también tratamiento y manejo medico postquirurgico , en el período de tiempo comprendido entre junio 2005 a julio 2013. Se analizaron las historias clínicas de 425 pacientes recibidos en el CES atendidos por …

Análisis De La Capacidad Diagnóstica De Zoonosis Neurológicas De Tipo Viral En Équidos En Cundinamarca, Ximena Bernal

Medicina Veterinaria

Las zoonosis de tipo viral en equinos, su detección y diagnóstico se han convertido en un reto para la salud pública en Colombia, ya que son enfermedades de declaración obligatoria ante las autoridades sanitarias y considerando la alta morbilidad y letalidad que estas enfermedades pueden llegar a causar en los équidos, se busca facilitar prácticas de manejo, de exportación e importación, eliminación, prevención y control. Teniendo en cuenta esto, se realizó el trabajo haciendo una comparación acerca de las pruebas diagnósticas realizadas en el departamento de Cundinamarca para este tipo de zoonosis y las realizadas internacionalmente, midiendo en términos de …

Efecto De Polipéptidos Linforeticulares, En Los Valores Hemáticos E Inmunoglobulina G En Un Grupo De Equinos De Paso Colombiano En Tabio, Cundinamarca, Diana Patricia Pacheco González, Adriana Paola Bermúdez Rodríguez

Medicina Veterinaria

Los Polipéptidos linforeticulares de origen esplénico y hepático porcino son una alternativa como inmunoestimulantes y coadyuvantes en diferentes procedimientos biológicos y enfermedades. Este tratamiento de apoyo metabólico se asocia al concepto de que la célula es una fábrica de proteínas y necesita por consiguiente de un soporte metabólico específico para si misma o un tejido en deterioro. El objetivo del trabajo fue determinar el efecto de los polipéptidos linforeticulares sobre los valores hemáticos y de inmunoglobulina G en un grupo de equinos de paso criollo Colombiano en Tabio, Cundinamarca. Se seleccionaron 20 equinos sanos del criadero Danielandia, separados en un …