Translational Medical Research Commons^™

Provision Of Pandemic Disease Information By Health Sciences Librarians: A Multisite Comparative Case Series., Robin Featherstone, Gabriel Boldt, Nazi Torabi, Shauna-Lee Konrad

Nazi Torabi

Objective: The research provides an understanding of pandemic information needs and informs professional development initiatives for librarians in disaster medicine. Methods: Utilizing a multisite, comparative case series design, the researchers conducted semi-structured interviews and examined supplementary materials in the form of organizational documents, correspondence, and websites to create a complete picture of each case. The rigor of the case series was ensured through data and investigator triangulation. Interview transcripts were coded using NVivo to identify common themes and points of comparison. Results: Comparison of the four cases revealed a distinct difference between “client-initiated” and “librarian-initiated” provision of pandemic information. Librarian-initiated …

Gender Does Not Influence The Relationship Between Posterior Cruciate Ligament Design And Patient-Reported Outcomes In Patients Receiving Primary Unilateral Total Knee Arthroplasty, Ryan Milan

Electronic Thesis and Dissertation Repository

The effect of the interaction between gender and posterior cruciate ligament (PCL) prosthesis design on patient-reported outcomes is an understudied area of research. We evaluated 1613 patients, from the Ontario Joint Replacement Registry (2001-2006), who underwent primary total knee replacement. This study investigated the impact of the gender-PCL design interaction on Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) change scores and patient satisfaction, by performing linear regression analysis, using full-adjusted models that also included the gender-PCL prosthesis design interaction variable. PCL prosthesis design did not affect WOMAC change scores or satisfaction (p>0.05). Moreover, Gender did not influence either …

Innovations In Primary Care: Implementing Clinical Care Management In Primary Care Practices, Sai Cherala

Sai Cherala

The Massachusetts Patient Centered Medical Home Initiative (MA PCMHI) is a statewide, multi-payer demonstration that seeks to transform 46 primary care practices into PCMHs. Clinical care management of high-risk patients is a key element of the PCMH and a new service for most primary care practices. Training for practices in the MA PCMHI includes the clinical care manager (CCM) role, identification/tracking of highest-risk patients, care plan development/implementation, care coordination, and communications. Content is delivered through learning collaborative sessions, monthly webinars and practice-based transformation facilitation. Assessment of progress towards implementation is made through practice-based data on clinical care management measures and …

Jefferson Hosts Third Interprofessional Education Conference, Kevin Lyons Phd, Christine Arenson Md, Elizabeth Speakman Rn, Phd, Carolyn Giordano Phd

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.

Genetic Risk Factors For Type 2 Diabetes: A Trans-Regulatory Genetic Architecture?, Steven C. Elbein, Eric R. Gamazon, Swapan K. Das, Neda Rasouli, Philip A. Kern, Nancy J. Cox

Clinical and Translational Science Faculty Publications

To date, 68 loci have been associated with type 2 diabetes (T2D) or glucose homeostasis traits. We report here the results of experiments aimed at functionally characterizing the SNPs replicated for T2D and glucose traits. We sought to determine whether these loci were associated with transcript levels in adipose, muscle, liver, lymphocytes, and pancreatic β-cells. We found an excess of trans, rather than cis, associations among these SNPs in comparison to what was expected in adipose and muscle. Among transcripts differentially expressed (FDR < 0.05) between muscle or adipose cells of insulin-sensitive individuals and those of insulin-resistant individuals (matched on BMI), trans-regulated transcripts, in contrast to the cis-regulated ones, were enriched. The paucity of …

Exploring Pregnant Women’S Perceptions And Decision Making Of Household Chemicals: Phthalates As A Model, Justin M. Ashley

Electronic Thesis and Dissertation Repository

Recent research has identified a group of plasticizers known as phthalates as potential anti-androgens and a risk to developing male fetuses. A constructivist grounded theory study was used to understand pregnant women and obstetrical care providers’ perceptions of phthalates. Twenty-three pregnant women and twelve obstetrical care providers (Obstetricians, Family Physicians, and Midwives) from Southwestern Ontario participated in semi-structured interviews. Pregnant women and clinicians had little knowledge regarding phthalates and the potential associated risks. Women felt that knowledge of these risks would be important to prenatal counselling while clinicians required more evidence. Two separate but related models emerged from the data …

The Effects Of A Group Visit Program On Outcomes Of Diabetes Care In An Urban Family Practice., Jeffrey A Reitz, Mona Sarfaty, James Diamond, Brooke Salzman

Department of Family & Community Medicine Faculty Papers

Diabetes mellitus is a prevalent chronic health condition associated with significant morbidity and mortality. Those with diabetes must acquire self-efficacy in the tasks necessary for them to successfully manage their disease. In this study, a controlled pre- and post-design was used to determine the effect of an adult support and education group visit program embedded in an urban academic family medicine practice on weight and the achievement of treatment goals for hemoglobin A1C, low-density lipoprotein (LDL) blood concentration, and blood pressure (BP) several months after it was implemented. Participants in the program were matched to a comparison group based on …

“We Should Be Listening To Our Elders”: Evaluation Of Transfer Of Indigenous Knowledge Between Anishinabe Youth And Elders, Kassandra Kulmann

Electronic Thesis and Dissertation Repository

Indigenous knowledge (IK) (knowledge held by Indigenous peoples regarding local environments, ways of life and culture) can potentially improve health and environment conditions. This thesis examines IK transfer between Anishinabe Elders and youth. A knowledge translation intervention was applied to address community concerns regarding decline of IK transfer between Elders and youth.

Youth were hired to participate in a summer school and interview Elders regarding environment and health issues. Qualitative interviews were conducted with youth before and after their internships to evaluate their experiences and IK uptake. The summer school and internships were effective for facilitating IK transfer between Elders …

How Do Parents Use Health Information With The Aid Of A Knowledge Broker When Living With And Caring For Their Young Children With Cerebral Palsy?, Stephanie E. Lagosky

Electronic Thesis and Dissertation Repository

This research aims to understand how parents use health information (such as those developed from the Move & PLAY study) with the aid of a knowledge broker when living with and caring for young children with cerebral palsy. This research was conducted under a qualitative case study methodology and used questionnaires and in-depth interviews to collect data. Findings include the complexity of both parental use of health information and the desire to use a knowledge broker. A provisional model has been created to help describe information use of parents with young children with cerebral palsy. This provisional model is an …

Stereotactic Ablative Radiotherapy For Comprehensive Treatment Of Oligometastatic Tumors (Sabr-Comet): Study Protocol For A Randomized Phase Ii Trial., Michael Lock

Michael Lock

No abstract provided.

Adherence To Canadian Best Practice Recommendations For Stroke Care: The Case Of Post-Stroke Depression, Katherine L. Salter

Electronic Thesis and Dissertation Repository

Context: Canadian best practice recommendations for identification and treatment of post-stroke depression (PSD) have been established, but whether they have been adopted is not known.

Objectives: To compare current with recommended best practice.

Methods: A retrospective chart review from 5 inpatient rehabilitation programs in Southwestern Ontario was completed and a short online survey addressing current practices, opinions and attitudes regarding PSD conducted.

Results: Screening for PSD was documented in 41 of 294 patient records. Of the 41 patients screened, 16 were referred for assessment and 6 diagnosed with PSD. However, 113 patients (38.9%) received pharmacotherapy. Most staff …

Community-Based Partnerships For Improving Chronic Disease Management, James Plumb, Laura Carson Weinsten, Rickie Brawer, Kevin Scott

Department of Family & Community Medicine Faculty Papers

With the growing burden of chronic disease, the medical and public health communities are re-examining their roles and opportunities for more effective prevention and clinical interventions. The potential to significantly improve chronic disease prevention and have an impact on morbidity and mortality from chronic conditions is enhanced by adopting strategies that incorporate a social ecology perspective, realigning the patient-physician relationship, integrating population health perspectives into the Chronic Care Model, and effectively engaging communities using established principles of community engagement.

Copyright © 2012 Elsevier Inc. All rights reserved.

An International Survey On Liver Metastases Radiotherapy, Michael Lock

Michael Lock

Abstract BACKGROUND: An international survey of radiation therapy (RT) of liver metastases was undertaken by the Liver Cancer Workgroup of the Third International Consensus on Metastases Workshop at the 2010 American Society for Radiation Oncology (ASTRO) meeting. MATERIAL AND METHODS: Canadian, European, Australian, New Zealand and American centers participated in this online survey. The survey had four objectives: 1) to describe the practice patterns for RT of liver metastases; 2) to report on the use of low-dose RT for symptomatic liver metastases; 3) to report on the use of technology; and 4) to describe the regional differences in the management …

Hearts And Minds: Examining The Evolution Of The Egyptian Excerebration And Evisceration Traditions Through The Impact Mummy Database, Andrew D. Wade

Electronic Thesis and Dissertation Repository

Egyptian mummification and funerary rituals were a transformative process, making the deceased a pure being; free of disease, injury, and disfigurements, as well as ethical and moral impurities. Consequently, the features of mummification available to specific categories of individuals hold social and ideological significance. This study refutes long-held classical stereotypes, particularly dogmatic class associations; demonstrates the apocryphal nature of universal heart retention; and expands on the purposes of excerebration and evisceration implied by synthetic and radiological analyses.

Features of the embalming traditions, specifically the variable excerebration and evisceration traditions, represented the Egyptian view of death. Fine-grain analyses, through primary imaging …

Provision Of Pandemic Disease Information By Health Sciences Librarians: A Multisite Comparative Case Series., Robin Featherstone, Gabriel Boldt, Nazi Torabi, Shauna-Lee Konrad

Western Libraries Publications

Objective: The research provides an understanding of pandemic information needs and informs professional development initiatives for librarians in disaster medicine. Methods: Utilizing a multisite, comparative case series design, the researchers conducted semi-structured interviews and examined supplementary materials in the form of organizational documents, correspondence, and websites to create a complete picture of each case. The rigor of the case series was ensured through data and investigator triangulation. Interview transcripts were coded using NVivo to identify common themes and points of comparison. Results: Comparison of the four cases revealed a distinct difference between “client-initiated” and “librarian-initiated” provision of pandemic information. Librarian-initiated …

Information Sharing To Promote Informed Choice In Prenatal Screening In The Spirit Of The Sogc Clinical Practice Guideline: A Proposal For An Alternative Model, Meredith G. Vanstone

Meredith Vanstone

The 2011 SOGC clinical practice guideline “Prenatal Screening for Fetal Aneuploidy in Singleton Pregnancies” recommends that clinicians offer prenatal screening to all pregnant women and provide counselling in a non-directive manner . Non-directive counselling is intended to facilitate autonomous decision-making and remove the clinician’s views regarding a particular course of action . However, recent research in genetic counselling raises concerns that nondirective counselling is neither possible nor desirable, and that it may not be the best way to facilitate informed choice . We propose an alternative model of information-sharing specific to prenatal screening that combines attributes of the models of …

An Exploration Of Knowledge Translation Amongst Homecare Providers, Family Caregivers, And Clients, L. Jansen

Electronic Thesis and Dissertation Repository

The aim of this two-phased investigation was to enhance understanding of urinary incontinence (UI) knowledge translation (KT) to inform how UI management knowledge might be translated within in-home nursing practice and family caregiving. Although UI can be managed conservatively, it is a principal reason for the breakdown of family-care and care recipient admission to long-term care. Research has afforded little insight into family caregivers’ experience of KT and the process of in-home KT for UI management.

The first study used a hermeneutic phenomenological approach to explore family caregivers’ experience of UI KT. Data were collected from in-depth interviews with a …

Improving Cancer Survivorships: Targeting Physical Activity And Inactivity At Teachable Moments, Siew Yim Loh Assoc Prof

Siew Yim Loh

This article presents a brief overview on the importance of adopting healthy behavior during and after the completion of primary cancer treatment. Increasing evidences are advocating physical activity engagement in cancer survivors due to its convincing beneficial outcomes. Today, outcomes from numerous trials confirmed the need to examine beyond physical activity engagement, into physical inactivity as an independent factor for cancer recurrences. Reducing cancer-risk related behaviors via increase physical activity and reduce inactivity is now receiving much attention in the field of cancer survivorship. Both realms of activity and inactivity are now acknowledged as influential independent factors contributing to better …

Barriers To Participation In A Randomized Controlled Trial Of, Siew Yim Loh Assoc Prof

Siew Yim Loh

range from patient-related, through institutional-related to staff-related factors. This paper highlights the low response rate and the recruitment barriers faced in our Qigong exercises trial. Materials and Method: The Qigong trial is a three-arm trial with a priori power size of 114 patients for 80% power. The University Malaya Medical Centre database showed a total of 1,933 patients from 2006-2010 and 751 patients met our inclusion criteria. These patients were approached via telephone interview. 131 out of 197 patients attended the trial and the final response rate was 48% (n=95/197). Results: Multiple barriers were identified, and were regrouped as patientrelated, …

Are We Ready To Address The New Expectations Of Work And Workers In The Transforming World Of Work?, Lynn Shaw Dr.

Lynn Shaw

This sounding board article focuses on the transformative world of work and the need to prevent occupational injustice for future workers and work places.

Work Transition Tips For Workers, Lynn Shaw Dr.

Lynn Shaw

No abstract provided.

Getting The Message Across: Principles For Developing Brief-Knowledge Transfer (B-Kt) Communiqués, Lynn Shaw Dr.

Lynn Shaw

Objective: This feature article on knowledge transfer presents principles and strategies to support the development of short communiqués to end-users. Participants: Formal and informal knowledge brokers are the targeted users of the strategies. Methods: Research studies and conceptual literature in knowledge transfer informed the development of brief-Knowledge Transfer (b-KT) principles. Principles are explained and a sample of how they informed the development of KIT-Tip Sheets is offered to promote ways to use principles in knowledge dissemination. Results: b-KT principles can be used as a framework to guide the development of short communiqués by knowledge brokers in work practice but also …

Improving Quit Rates For Tobacco-Dependent Hospitalized Patients, Marion G. Mann

UNF Graduate Theses and Dissertations

Abstract

Purpose: The purpose of this project was to evaluate outcomes of an existing inpatient tobacco cessation counseling program with 30-day follow-up among recently admitted tobacco-dependent patients who were tobacco-dependent.

Background/Significance: Tobacco use is considered the number one most preventable cause of disease, disability, and death in the United States. Despite associated dangers, approximately 21% Americans currently smoke. This has led to increased hospital admissions and chronic disease management, costing the United States approximately $96 billion per year. Decades of research and evidence-based clinical practice guidelines substantiate that inpatient tobacco cessation counseling has the potential to improve quit rates post-hospital …

The Career Support Network (Csn): Workforce Programming Through A New Lens, Rickie Brawer, Mph, Phd, James D. Plumb Md, Mph, Stephen Kern, Phd, Otr/L, Faota

Department of Family & Community Medicine Faculty Papers

Challenges:

Loss of Earn center as referral source

Multiple IRB submissions

Training/orientation at Philadelphia Prison System for working with pre-release prisoners

Service team organization/scheduling

Coordinating of cohorts at various stages of enrollment

Sepa-Reads: Cardiovascular Health Literacy Coalition, Rickie Brawer, Mph, Phd, James D. Plumb Md, Mph, Rob Simmons Drph,Mph,Ches, Martha Romney Rn,Ms,Jd,Mph, Patricia Yurchick, Rn, Mba, Cphq, Leslie Stearns

Department of Family & Community Medicine Faculty Papers

Poster includes:

Health literacy definition

Factors that contribute to health literacy

Extent of the literacy problem

What do we know from a decade of research?

Readmission rates

Evaluation: long and short term outcomes

And much more.

The International Effort: Building The Bridge For Translational Medicine: Report Of The 1st International Conference Of Translational Medicine (Ictm), Xiaoming Chen, Roland Andersson, William Cs Cho, David Christiani, Richard Coico, Jeffery Drazen, Markus Ege, Thomas Fehniger, Hongwei Gao, Kunlin Jin, Michael N. Liebman, Elena Lopez, Giuseppe Marraro, Gyorgy Marko-Varga, Francesco M. Marincola, Laurentiu M. Popescu, Claudio Spada, Aamir Shahzad, Ena Wang, Wei Wang, Xiangdong Wang, Yong-Xiao Wang, Jinglin Xia, Jia Qu

Research outputs 2012

Background : Supported by the International Society for Translational Medicine (ISTM), Wenzhou Medical College and the First Affiliated Hospital of Wenzhou Medical College, the International Conference on Translational Medicine (ICTM) was held on October 22–23, 2011 in Wenzhou, China. Nearly 800 registrants attended the meeting, primarily representing institutes and hospitals in Europe, The United States of America, And Asia, and China. The meeting was chaired and organized by Dr. Xiangdong Wang, Xiaoming Chen, Richard Coico, Jeffrey M. Drazen, Richard Horton, Francesco M. Marincola, Laurentiu M. Popescu, Jia Qu and Aamir Shahzad.

Findings : The meeting focused on the communication of …

Using A Dnp-Led Transitional Care Program To Prevent Rehospitalization In Elderly Patients With Heart Failure Or Chronic Obstructive Pulmonary Disease, Moira L. Long,

Doctor of Nursing Practice (DNP) Projects

ABSTRACT: TRANSITIONAL CARE FOR PATIENTS WITH CHRONIC DISEASE

BACKGROUND OF PROBLEM:

The Affordable Care Act of 2010 has put a spotlight on ensuring safe patient transfers between health care settings to prevent rehospitalization. Hospital readmissions are often influenced by a lack of outpatient transitional care programs to ensure the continuity of care during the transition from the inpatient setting to home. This gap in continuity further exacerbates the issues of patient management of medication regimens, adverse drug events, and follow-up with providers. These exacerbations combined with ineffective symptom management can all result in decompensation and rehospitalization. An extensive review of …

Research Annual Report 2012, Children's Mercy Hospital

Research Annual Reports

Annual report of the research at Children's Mercy Hospital in Kansas City MO, a pediatric medical center.

The New First Amendment And Its Implications For Combating Obesity Through Regulation Of Advertising, Tamara R. Piety, Samantha Graff

Tamara R. Piety

This chapter reviews the recent decisions of the Supreme Court as they bear on attempts to combat childhood obesity through regulating marketing and concludes that attempts to regulate marketing will face substantial First Amendment obstacles in the courts.

Mechanisms Of An Occupation-Based Approach For Persons With Chronic Pain And Work Loss., J. Scott, R. Hills, A. Schmidt, J. Stroud, C. Kerr, Lynn Shaw Dr., A. Bossers

Lynn Shaw

Current literature demonstrates a significant investigation of chronic pain. The actual mechanisms that promote adaptation, accommodation, and change, however, are not explicated in the current literature on chronic pain. Our goal was to conduct a mini realist synthesis approach in current literature to identify mechanisms critical to promote return to work (RTW) for persons with chronic pain. Specifically, we sought to identify if the mechanisms of these programs are consistent with an occupation-based approach used in Occupational Therapy (OT).