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Full-Text Articles in Nanotechnology
Peptide Functionalized Surfactant Msns, Sonia Barrett
Peptide Functionalized Surfactant Msns, Sonia Barrett
Kansas State University Undergraduate Research Conference
Antibiotic resistance in bacteria has become a rising problem since the first antibiotic was created, further aggravated by the improper overuse to treat common infections, because of this pharmaceutical companies must keep making new and stronger antibiotics. Surfactants are plentiful and effective killers of many surface bacteria and are also varied in their structure, all have a hydrophilic head and long hydrophobic carbon chain. These long hydrophobic carbon chains can pierce through the lipid bilayers that make up bacteria cell membranes and cause cytoplasmic leakage and lysis of the cell wall, leading to cell death. One proposed surfactant is synthesized …
Peptide Conjugation Of Branched Amphiphilic Peptide Capsules, Baltazar Claro-Martinez
Peptide Conjugation Of Branched Amphiphilic Peptide Capsules, Baltazar Claro-Martinez
Kansas State University Undergraduate Research Conference
In recent years, nanocarrier cellular therapy has been a rapidly growing area for research in the treatment of malignant and infectious diseases – most notably cancer. Conventional cancer treatment has consisted of highly toxic, highly insoluble, untargeted delivery of drugs that kill both cancerous and healthy cells. Research in the Tomich lab consists of the synthesis of Branched Amphiphilic Peptide Capsules (BAPCs), which are self-assembling peptide nanospheres composed of one or both of these branched peptide sequences: h5 and h9. These peptides possess similar molecular characteristics of phosphoglycerides but are synthesized chemically within the lab. Previous publications by the Tomich …
Therapeutic Peptide Sequences And Gatekeepers Loaded With Mesoporous Silica Nanoparticles, Dursitu Hassen
Therapeutic Peptide Sequences And Gatekeepers Loaded With Mesoporous Silica Nanoparticles, Dursitu Hassen
Kansas State University Undergraduate Research Conference
The research community is developing and looking into new ways of effectively delivering anti-cancer treatment. According to National Cancer Institute over 1.5 million new cases of cancer are predicted in the United States, just alone in 2018. The major hurdles that have been identified by scientists are finding mechanisms that assist in decreasing the side effects of cancer treatment and to increase the effectiveness of the drug. In our lab, a highly toxic peptide sequence, SA-K6L9-AS is encapsulated in MSNs (mesoporous silica nanoparticles) and capped with a gatekeeper. The function of a gatekeeper is preventing the …
Design Of Sensors For In-Vivo Detection Of Cancer Related Enzymes, Laura Soto
Design Of Sensors For In-Vivo Detection Of Cancer Related Enzymes, Laura Soto
Kansas State University Undergraduate Research Conference
Cancer continues to be among the leading causes of death worldwide. In 2018, there were approximately 9.6 million cancer deaths, just in the United States alone, there were 1.7 million new cancer cases and 600,000 deaths. That is why, there is an urgent need for better ways to battle cancer. Therefore, the goal of this project is to create a nanobiosensor which would have T1 and T2 based imaging capabilities to measure cancer enzymatic activity. The diagnostic tool would be useful to differentiate between benign and malignant tumors in-vivo and to quantify the effect of cancer treatments, such …