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Masters Theses

James Madison University

Other Medicine and Health Sciences

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The Effect Of Acute Aerobic Exercise On Hemostasis In Obstructive Sleep Apnea Patients, Ryan A. Martin May 2016

The Effect Of Acute Aerobic Exercise On Hemostasis In Obstructive Sleep Apnea Patients, Ryan A. Martin

Masters Theses

Purpose: To determine the hemostatic response after acute aerobic exercise in Obstructive Sleep Apnea (OSA). Methods: Eighteen males were recruited from the university and local community. Individuals who presented evidence of cardiovascular, pulmonary, or metabolic disease were excluded. Apnea-Hypopnea Index (AHI) > 5 was criteria for OSA. Subjects performed a treadmill exercise test at 35% and 70% predicted VO2reserve during the morning hours. Pre exercise blood samples were obtained after 15 minutes supine rest and within two minutes following exercise. Repeated Measures ANOVA were performed for Factor VIII antigen, tPA antigen, tPA activity, and PAI-1 activity across two time ...