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Articles 1 - 4 of 4
Full-Text Articles in Medical Physiology
Gelatinase Activity In The Mouse Uterus During Early Pregnancy, Carol A. Brenner, Richard R. Adler, Gary L. Nieder
Gelatinase Activity In The Mouse Uterus During Early Pregnancy, Carol A. Brenner, Richard R. Adler, Gary L. Nieder
Gary L. Nieder
No abstract provided.
Gelatinase Activity In The Mouse Uterus During Early Pregnancy, Carol A. Brenner, Richard R. Adler, Gary L. Nieder
Gelatinase Activity In The Mouse Uterus During Early Pregnancy, Carol A. Brenner, Richard R. Adler, Gary L. Nieder
Neuroscience, Cell Biology & Physiology Faculty Publications
No abstract provided.
Differentiation Of Renal Beta-Intercalated Cells To Alpha-Intercalated And Principal Cells In Culture., Geza Fejes-Tóth, Aniko Náray-Fejes-Tóth
Differentiation Of Renal Beta-Intercalated Cells To Alpha-Intercalated And Principal Cells In Culture., Geza Fejes-Tóth, Aniko Náray-Fejes-Tóth
Dartmouth Scholarship
The renal collecting duct is a heterogenous epithelium consisting of intercalated cells (ICC) and principal cells (PC). The origin of this cellular heterogeneity is not clear. To test the hypothesis that the two cell types might originate from one another, pure populations of ICC (beta subtype) and PC were isolated by fluorescence-activated cell sorting and grown on permeable supports. After the monolayers reached confluence, the expression of ICC- and PC-specific functions and antigens was monitored. Cultures of sorted beta-ICC, in addition to expressing ICC-specific functions (such as an electrogenic H+ secretion) and antigens, progressively acquired PC functions (amiloride-sensitive Na+ transport …
Anion Permeation In An Apical Membrane Chloride Channel Of A Secretory Epithelial Cell, Dan R. Halm, Raymond A. Frizzell
Anion Permeation In An Apical Membrane Chloride Channel Of A Secretory Epithelial Cell, Dan R. Halm, Raymond A. Frizzell
Neuroscience, Cell Biology & Physiology Faculty Publications
Single channel currents though apical membrane Cl channels of the secretory epithelial cell line T84 were measured to determine the anionic selectivity and concentration dependence of permeation. The current-voltage relation was rectified with single channel conductance increasing at positive potentials. At 0 mV the single channel conductance was 41 ± 2 pS. Permeability, determined from reversal potentials, was optimal for anions with diameters between 0.4 and 0.5 nm. Anions of larger diameter had low permeability, consistent with a minimum pore diameter of 0.55 nm. Permeability for anions of similar size was largest for those ions with a more symmetrical charge …