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Medical Biotechnology Commons

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Full-Text Articles in Medical Biotechnology

Selecting Medical Hardware Using Pairwise Comparisons: A Patient's Perspective Of Cochlear Implant Device Selection, Timothy R. Anderson, Shabnam Razeghian Jahromi Sep 2016

Selecting Medical Hardware Using Pairwise Comparisons: A Patient's Perspective Of Cochlear Implant Device Selection, Timothy R. Anderson, Shabnam Razeghian Jahromi

Engineering and Technology Management Faculty Publications and Presentations

Selecting medical hardware can be a difficult and permanent decision for patients that they are often unprepared for. The authors explore the use of pairwise comparison techniques to better inform medical decision making in an application of choosing between three major cochlear implant manufacturers. This paper appears to be the first study to apply a pairwise comparison decision making approach for cochlear implant device selection. Also, unlike many medical decision making studies that are developed by the healthcare professional, this model and analysis was conducted entirely by the patient for the purpose of making the real-world decision of a device. …


An Informational Algorithm As The Basis For Perception-Action Control Of The Instantaneous Axes Of The Knee, Wangdo Kim, Margarida M. Espanha, António P. Veloso, Duarte Araújo, Filipa João, Luis Carrão, Sean S. Kohles Mar 2013

An Informational Algorithm As The Basis For Perception-Action Control Of The Instantaneous Axes Of The Knee, Wangdo Kim, Margarida M. Espanha, António P. Veloso, Duarte Araújo, Filipa João, Luis Carrão, Sean S. Kohles

Mechanical and Materials Engineering Faculty Publications and Presentations

Traditional locomotion studies emphasize an optimization of the desired movement trajectories while ignoring sensory feedback. We propose an information based theory that locomotion is neither triggered nor commanded but controlled. The basis for this control is the information derived from perceiving oneself in the world. Control therefore lies in the human-environment system. In order to test this hypothesis, we derived a mathematical foundation characterizing the energy that is required to perform a rotational twist, with small amplitude, of the instantaneous axes of the knee (IAK). We have found that the joint’s perception of the ground reaction force may be replaced …


Dynamic Matrix Composition In Engineered Cartilage With Stochastic Supplementation Of Growth Factors, Asit K. Saha, J. (Jagannath) Mazumdar, Sean S. Kohles Jun 2005

Dynamic Matrix Composition In Engineered Cartilage With Stochastic Supplementation Of Growth Factors, Asit K. Saha, J. (Jagannath) Mazumdar, Sean S. Kohles

Mechanical and Materials Engineering Faculty Publications and Presentations

Dynamic extracellular matrix (ECM) synthesis is explored in a hypothesized engineered cartilage construct. Growth (α) and decay (β) rate parameters are developed from a previous engineered cartilage model. The presented mathematical model was constructed from the parameterized experimental data using a deterministic and stochastic examination of ECM synthesis based on a negative feedback control mechanism. A growth factor supplementation is incorporated in a probabilistic mathematical approach. The growth factor component modified an initial deterministic model through a Gaussian white noise fluctuation. As the primary constituents of ECM, the mathematical tool is intended to characterize the probable steady state distribution of …