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Medical Biomathematics and Biometrics Commons™
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Articles 1 - 7 of 7
Full-Text Articles in Medical Biomathematics and Biometrics
Demographics Of Periprosthetic Joint Infection Rates, Katelynn Donnelly, Abigail Erwin, Andrew Chapple, Peter Krause, Vinod Dasa
Demographics Of Periprosthetic Joint Infection Rates, Katelynn Donnelly, Abigail Erwin, Andrew Chapple, Peter Krause, Vinod Dasa
Medical Research Day
Introduction: Risk factors for periprosthetic joint infections (PJIs) following total joint arthroplasties (TJAs) include patient demographics and comorbidities such as age, gender, obesity, rheumatoid arthritis, and diabetes. 1 However, there is insufficient research analyzing the number of PJIs in certain racial subsets of the population despite the presence of disparities due to race that still exists in orthopedics today. 2 The purpose of this study is to investigate if PJI rates differ by race, as well as other patient demographics. This may uncover valuable information on how race relates to PJIs which is frequently unaccounted for in other studies. This …
Lack Of Demographic Information In Tha/Tka Randomized Controlled Trial Publications, Katelynn Donnelly, Hannah Theriot, John Bourgeois, Andrew Chapple, Peter Krause, Vinod Dasa
Lack Of Demographic Information In Tha/Tka Randomized Controlled Trial Publications, Katelynn Donnelly, Hannah Theriot, John Bourgeois, Andrew Chapple, Peter Krause, Vinod Dasa
Medical Research Day
Introduction: The impact of social determinants of health (SDOH) has been documented in orthopedic literature. However, there is a lack of data on the inclusion of these variables in orthopedic studies. Our aim was to investigate how many THA and TKA randomized controlled trials (RCTs) report SDOH variables such as race, ethnicity, insurance, income, and education within the manuscript. Methods: A literature review was conducted on a PubMed search for RCTs published from 2017-2019 in 4 major orthopedic journals which routinely publish on total joint arthroplasty: JBJS, Journal of Arthroplasty, CORR, and Osteoarthritis and Cartilage. The inclusion criteria, THA/TKA RCTs …
Demographics Of Periprosthetic Joint Infections Rates, Katelynn Donnelly, Abigail Erwin, Andrew Chapple, Peter Krause, Vinod Dasa
Demographics Of Periprosthetic Joint Infections Rates, Katelynn Donnelly, Abigail Erwin, Andrew Chapple, Peter Krause, Vinod Dasa
Medical Research Day
Introduction: Risk factors for periprosthetic joint infections (PJIs) following total joint arthroplasties (TJAs) include patient demographics and comorbidities such as age, gender, obesity, rheumatoid arthritis, and diabetes. However, there is insufficient research analyzing the number of PJIs in certain racial subsets of the population despite the presence of disparities due to race that still exists in orthopedics today. The purpose of this study is to investigate if PJI rates differ by race, as well as other patient demographics. This may uncover valuable information on how race relates to PJIs which is frequently unaccounted for in other studies. This study aims …
Neutrophil Dynamics Affect Mycobacterium Tuberculosis Granuloma Outcomes And Dissemination, Caitlin Hult, Joshua T. Mattila, Hannah P. Gideon, Jennifer J. Linderman, Denise E. Kischner
Neutrophil Dynamics Affect Mycobacterium Tuberculosis Granuloma Outcomes And Dissemination, Caitlin Hult, Joshua T. Mattila, Hannah P. Gideon, Jennifer J. Linderman, Denise E. Kischner
Math Faculty Publications
Neutrophil infiltration into tuberculous granulomas is often associated with higher bacteria loads and severe disease but the basis for this relationship is not well understood. To better elucidate the connection between neutrophils and pathology in primate systems, we paired data from experimental studies with our next generation computational model GranSim to identify neutrophil-related factors, including neutrophil recruitment, lifespan, and intracellular bacteria numbers, that drive granuloma-level outcomes. We predict mechanisms underlying spatial organization of neutrophils within granulomas and identify how neutrophils contribute to granuloma dissemination. We also performed virtual deletion and depletion of neutrophils within granulomas and found that neutrophils play …
Decoding Clinical Biomarker Space Of Covid-19: Exploring Matrix Factorization-Based Feature Selection Methods, Farshad Saberi-Movahed, Mahyar Mohammadifard, Adel Mehrpooya, Mohammad Rezaei-Ravari, Kamal Berahmand, Mehrdad Rostami, Saeed Karami, Mohammad Najafzadeh, Davood Hajinezhad, Mina Jamshidi, Farshid Abedi, Mahtab Mohammadifard, Elnaz Farbod, Farinaz Safavi, Mohammadreza Dorvash, Shahrzad Vahedi, Mahdi Eftekhari, Farid Saberi-Movahed, Iman Tavassoly
Decoding Clinical Biomarker Space Of Covid-19: Exploring Matrix Factorization-Based Feature Selection Methods, Farshad Saberi-Movahed, Mahyar Mohammadifard, Adel Mehrpooya, Mohammad Rezaei-Ravari, Kamal Berahmand, Mehrdad Rostami, Saeed Karami, Mohammad Najafzadeh, Davood Hajinezhad, Mina Jamshidi, Farshid Abedi, Mahtab Mohammadifard, Elnaz Farbod, Farinaz Safavi, Mohammadreza Dorvash, Shahrzad Vahedi, Mahdi Eftekhari, Farid Saberi-Movahed, Iman Tavassoly
Publications and Research
One of the most critical challenges in managing complex diseases like COVID-19 is to establish an intelligent triage system that can optimize the clinical decision-making at the time of a global pandemic. The clinical presentation and patients’ characteristics are usually utilized to identify those patients who need more critical care. However, the clinical evidence shows an unmet need to determine more accurate and optimal clinical biomarkers to triage patients under a condition like the COVID-19 crisis. Here we have presented a machine learning approach to find a group of clinical indicators from the blood tests of a set of COVID-19 …
The Effect Of Using Bolometric Exercises On Enhancing Explosive Strength Among Female Students Of The Faculty Of Physical Education At Yarmouk University, Mohammed A. Mqableh, Sulaiman M. Qazaqzeh, Bassam M. Khalifa, Sumayeh M. Ekhwelah
The Effect Of Using Bolometric Exercises On Enhancing Explosive Strength Among Female Students Of The Faculty Of Physical Education At Yarmouk University, Mohammed A. Mqableh, Sulaiman M. Qazaqzeh, Bassam M. Khalifa, Sumayeh M. Ekhwelah
Journal of the Association of Arab Universities for Research in Higher Education (مجلة اتحاد الجامعات العربية (للبحوث في التعليم العالي
The Effect of Using bolometric Exercises on Enhancing Explosive Strength among Female Students of the Faculty of Physical Education at Yarmouk University. The study purpose was to identify the effect of bolometric exercises on improving the explosive force of female students in the Faculty of Physical Education at Yarmouk University. The researchers used the experimental method. The sample consisted of 22 students in the course of preparation and physical fitness for the first semester of the academic year (2018-2019) and the sample was chosen by randomly. The researchers designed a training program that includes training exercises, consisting of (18) training …
Covid19 Disease Map, A Computational Knowledge Repository Of Virus–Host Interaction Mechanisms, Marek Ostaszewski, Tomáš Helikar, Bhanwar Lal Puniya, A Host Of Co-Authors, Covid-19 Disease Map Community
Covid19 Disease Map, A Computational Knowledge Repository Of Virus–Host Interaction Mechanisms, Marek Ostaszewski, Tomáš Helikar, Bhanwar Lal Puniya, A Host Of Co-Authors, Covid-19 Disease Map Community
Department of Biochemistry: Faculty Publications
We need to effectively combine the knowledge from surging literature with complex datasets to propose mechanistic models of SARS-CoV-2 infection, improving data interpretation and predicting key targets of intervention. Here, we describe a large-scale community effort to build an open access, interoperable and computable repository of COVID-19 molecular mechanisms. The COVID-19 Disease Map (C19DMap) is a graphical, interactive representation of disease-relevant molecular mechanisms linking many knowledge sources. Notably, it is a computational resource for graph-based analyses and disease modelling. To this end, we established a framework of tools, platforms and guidelines necessary for a multifaceted community of biocurators, domain experts, …