Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Life Sciences (3)
- Biochemistry (2)
- Biochemistry, Biophysics, and Structural Biology (2)
- Chemicals and Drugs (2)
- Medical Specialties (2)
-
- Pharmaceutical Preparations (2)
- Biomechanics (1)
- Biotechnology (1)
- Chemistry (1)
- Diseases (1)
- Disorders of Environmental Origin (1)
- Endocrinology, Diabetes, and Metabolism (1)
- Exercise Science (1)
- Inorganic Chemicals (1)
- Kinesiology (1)
- Medicinal-Pharmaceutical Chemistry (1)
- Molecular Biology (1)
- Obstetrics and Gynecology (1)
- Oncology (1)
- Organic Chemicals (1)
- Other Chemicals and Drugs (1)
- Physical Sciences and Mathematics (1)
- Reproductive and Urinary Physiology (1)
- Institution
- Keyword
-
- Alginate (1)
- Alginates (1)
- Allosteric Integrase inhibitors (1)
- Alpha-tocopherol (1)
- Ascorbic acid (1)
-
- Biotechnology (1)
- Boronates (1)
- CANDLES (1)
- Caveolin (1)
- Chromatography (1)
- Endocrinology (1)
- FSH (1)
- GPCR (1)
- Glucuronate (1)
- Glucuronides (1)
- HIV-1 Integrase Multimerization (1)
- Human Immunodeficiency Virus (1)
- Infertility (1)
- Lectin (1)
- Lectins (1)
- Lipid Rafts (1)
- Metastatic breast cancer (1)
- Quantification (1)
- Reactive oxygen species (1)
- Recombinant proteins (1)
- Reproducibility (1)
- Reproduction (1)
- Thesis (1)
Articles 1 - 6 of 6
Full-Text Articles in Medical Biochemistry
The Effects Of Alpha-Tocopherol And Ascorbic Acid On Metastatic Breast Cancer Cells, Scout Treadwell
The Effects Of Alpha-Tocopherol And Ascorbic Acid On Metastatic Breast Cancer Cells, Scout Treadwell
Honors Theses
Breast cancer is a multifaceted, complex disease that affects hundreds of thousands of patients every year. Although there has a been a decline in the mortality rate of this disease, it is still vital to investigate and discover new possible treatments. One area of research involves the generation of reactive oxygen species (ROS) in cancer cells and the possibility of ROS-induced apoptosis. Antioxidants such as Vitamin C and Vitamin E have been shown to serve as pro-oxidants. Instead of detoxifying the cell from damaging ROS, these compounds can stimulate ROS production, triggering an apoptotic cascade in the cell. In this …
Lectin Properties Of Synthetically Produced Glucuronate, Alginate, And Related Boronates, Vanessa Angel
Lectin Properties Of Synthetically Produced Glucuronate, Alginate, And Related Boronates, Vanessa Angel
Honors Theses
In the nineteenth century, researchers discovered that some proteins had the ability to agglutinate red blood cells (Goldstein, 1980). These proteins were found mainly in the seeds of leguminous plants and were named phytohemagglutinins or hemagglutinins. Particular hemagglutinins were able to agglutinate red blood cells (RBCs) of a specific blood type. Now a days, these proteins are more widely known as Lectins. Lectins are proteinaceous macromolecules of nonimmune origin, capable of interacting with carbohydrates to form complexes (Goldstein, 1980). Lectins sources derive mainly from leguminous plants, animals, fruiting bodies of fungi, and bacteria. This research focuses on identifying the lectin …
Mutations In The Human Follicle Stimulating Hormone Receptor Caveolin Interaction Motif Cause Increased Basal Activation, Elizabeth Altman
Mutations In The Human Follicle Stimulating Hormone Receptor Caveolin Interaction Motif Cause Increased Basal Activation, Elizabeth Altman
Honors Theses
Over twelve percent of women aged fifteen to forty-five in America suffer from infertility and/or impaired fecundity and over seven million women have used infertility services, such as intrauterine insemination and in vitro fertilization. Some cases of infertility may be due to dysfunctional human follicle stimulating hormone (hFSH) signaling. hFSH plays a role in spermatogenesis in males, as well as follicle maturation and estrogen production in females. Problems with either hFSH or the hFSH receptor (hFSHR) decrease fertility in males and cause complete infertility in females. As part of the hypothalamic-pituitary-gonadal axis, hFSH is released from the pituitary gland and …
Hiv-1 Integrase Multimerization By Quinoline Based Drugs, Samer Beauti
Hiv-1 Integrase Multimerization By Quinoline Based Drugs, Samer Beauti
Honors Theses
Human Immunodeficiency Virus Type 1 (HIV-1), a single stranded RNA retrovirus, affects over 30,000,000 people world-wide1. The virus works by infecting and promoting destruction of CD4 immune cells. and thus, suppressing proper immune functions2. Contrary to DNA viruses, the absence of extensive proofreading mechanisms in RNA viruses makes HIV latency a major obstacle in the discovery of long-term, effective treatments. Moreover, the importance of exploring novel therapeutic targets and designing complimentary inhibitory molecules remains steadfast in HIV research3 Recently, HIV-1 Integrase (IN) multimerization, the core enzyme used for integration of the viral DNA into an invaded host chromosome, has been …
Effects Of Aging & Exercise On Production Of Glial Cell Line-Derived Neurotrophic Factor Protein By Fast & Slow Skeletal Muscle, Maria Jaramillo
Effects Of Aging & Exercise On Production Of Glial Cell Line-Derived Neurotrophic Factor Protein By Fast & Slow Skeletal Muscle, Maria Jaramillo
Honors Theses
Exercise is a positive form of reinforcing positive lifestyle choices. There are many benefits to exercising such as decreased risk of cardiovascular disease and improved mental condition (Centers for Disease Control and Prevention). In addition, exercise can serve a protecting role for the nervous system. One form in which exercise can protect the nervous system is by increasing the production of neurotrophic factors, specifically glial cell line-derived neurotrophic factor. Another way by which exercise can protect the nervous system is by preserving muscle tissue due to actively recruiting it. The goal of this study was to explore the effects of …
Sds Non-Acrylamide Polymeric Gel-Filled Capillary Electrophoresis For Molecular Size Separation Of Protein, Devon Andres
Sds Non-Acrylamide Polymeric Gel-Filled Capillary Electrophoresis For Molecular Size Separation Of Protein, Devon Andres
Honors Theses
Sodium dodecyl sulfide (SDS) non-acrylamide gel-filled capillary columns are a new technology being used for analysis and separation of biotechnology-derived proteins. This research was to compare this new technology to the current methods of SDS polyacrylamide gel electrophoresis (SDS-PAGE) and high-performance size-exclusion chromatography (HPSEC). The molecular mass of four different recombinant proteins were determined by two commercialized SDS non-acrylamide gel-filled capillary columns, SDS-PAGE, and HPSEC. The data obtained showed that the SDS non-acrylamide gel-filled capillary columns were compatible with the SDS-PAGE technique for molecular mass determination. HPSEC was shown to be unreliable for molecular weight determination. SDS non-acrylamide gel-filled capillary …