Diseases Commons^™

Long-Acting Cabotegravir And The Emergence Of Drug-Resistant Hiv, Katharine Gurski

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Educational Case: Endometrial Ectopia In Endometriosis And Adenomyosis, Carolyn G. Chen, Joanna S.Y. Chan

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

No abstract provided.

Transmission Of Yellow Fever Vaccine Virus Through Blood Transfusion And Organ Transplantation In The Usa In 2021: Report Of An Investigation, Carolyn V. Gould, Rebecca J. Free, Julu Bhatnagar, Raymond A. Soto, Tricia L. Royer, Warren R. Maley, Sean Moss, Matthew A. Berk, Rebecca Craig-Shapiro, Rosy Priya L. Kodiyanplakkal, Lars F. Westblade, Thangamani Muthukumar, Yoram A. Puius, Amresh Raina, Azam Hadi, Kymberly A. Gyure, Danielle Trief, Marcus Pereira, Matthew J. Kuehnert, Vennus Ballen, Debra A. Kessler, Kimberly Dailey, Charles Omura, Thuy Doan, Steve Miller, Michael R. Wilson, Jennifer A. Lehman, Jana M. Ritter, Elizabeth Lee, Luciana Silva-Flannery, Sarah Reagan-Steiner, Jason O. Velez, Janeen J. Laven, Kelly A. Fitzpatrick, Amanda Panella, Emily H. Davis, Holly R. Hughes, Aaron C. Brault, Kirsten St George, Amy B. Dean, Joel Ackelsberg, Sridhar V. Basavaraju, Charles Y. Chiu, J. Erin Staples

Department of Medicine Faculty Papers

BACKGROUND: In 2021, four patients who had received solid organ transplants in the USA developed encephalitis beginning 2-6 weeks after transplantation from a common organ donor. We describe an investigation into the cause of encephalitis in these patients.

METHODS: From Nov 7, 2021, to Feb 24, 2022, we conducted a public health investigation involving 15 agencies and medical centres in the USA. We tested various specimens (blood, cerebrospinal fluid, intraocular fluid, serum, and tissues) from the organ donor and recipients by serology, RT-PCR, immunohistochemistry, metagenomic next-generation sequencing, and host gene expression, and conducted a traceback of blood transfusions received by …

Identification Of Potential Non-Invasive Biomarkers In Diastrophic Dysplasia, Chiara Paganini, Ricki S. Carroll, Chiara Gramegna Tota, Andrea J. Schelhaas, Alessandra Leone, Angela L. Duker, David A. O'Connell, Ryan F. Coghlan, Brian Johnstone, Carlos R. Ferreira, Sabrina Peressini, Riccardo Albertini, Antonella Forlino, Luisa Bonafé, Ana Belinda Campos-Xavier, Andrea Superti-Furga, Andreas Zankl, Antonio Rossi, Michael B. Bober

Student Papers, Posters & Projects

Diastrophic dysplasia (DTD) is a recessive chondrodysplasia caused by pathogenic variants in the SLC26A2 gene encoding for a cell membrane sulfate/chloride antiporter crucial for sulfate uptake and glycosaminoglycan (GAG) sulfation. Research on a DTD animal model has suggested possible pharmacological treatment approaches. In view of future clinical trials, the identification of non-invasive biomarkers is crucial to assess the efficacy of treatments. Urinary GAG composition has been analyzed in several metabolic disorders including mucopolysaccharidoses. Moreover, the N-terminal fragment of collagen X, known as collagen X marker (CXM), is considered a real-time marker of endochondral ossification and growth velocity and was studied …

Impact Of The Covid-19 Pandemic On The Management Of Risk Factors In Patients With Stable Atherosclerotic Vascular Disease, Dean Karalis, Patrick Moeller, Albert Crawford, Maria Janelli, Scott Hessen

Division of Cardiology Faculty Papers

Background

Effective control of risk factors in patients with ASCVD is important to reduce recurrent cardiovascular events. However, many ASCVD patients do not have their risk factors controlled, and this may have worsened during the COVID-19 pandemic.

Methods

We retrospectively evaluated risk factor control among 24,760 ASCVD patients who had at least 1 outpatient encounter both pre-pandemic and during the first year of the pandemic. Risk factors were uncontrolled if the blood pressure (BP) ≥ 130/80 mm Hg, LDL-C ≥ 70 mg/dL, HgbA1c ≥ 7 for diabetic patients, and patients were current smokers.

Results

During the pandemic, many patients had …

30th Annual Scientific Congress Of Hong Kong College Of Cardiology Proceedings

Journal of the Hong Kong College of Cardiology

No abstract provided.

Clinical Characteristics And Implications Of Bradycardia In Covid‐19 Patients Treated With Remdesivir: A Single‐Center Retrospective Cohort Study, Ariyon Schreiber, Justin S. Bauzon, Kavita Batra, Salman Mohammed, Kevin Lee, Nazanin Houshmand, Uyen Pham, Celica Cosme, Kim Inciong, Omar Al‑Taweel, Keaton Nasser, Jibran Rana, Chris Sossou, Ariel Go, Dalia Hawwass, Jimmy Diep, Chowdhury H. Ahsan

School of Medicine Faculty Publications

Background and Objectives: Remdesivir is an antiviral drug used to treat coronavirus disease 2019 (COVID-19) with a relatively obscure cardiac efect profle. Previous studies have reported bradycardia associated with remdesivir, but few have examined its clinical characteristics. The objective of this study was to investigate remdesivir associated bradycardia and its associated clinical characteristics and outcomes. Methods: This is a single-institution retrospective study that investigated bradycardia in 600 patients who received remdesivir for treatment of COVID-19. A total of 375 patients were included in the study after screening for other known causes of bradycardia (atrioventricular [AV] nodal blockers). All patients were …

Psychedelics Can Save: The Scientific And Social Case For Rescheduling Psychedelic Compounds, Galen M. Fader

Chancellor’s Honors Program Projects

No abstract provided.

Ua94/6/1 Clinic Covid-19 Reflections - Decker, A. Decker

Student/Alumni Personal Papers

Reflections on the Covid-19 by WKU Communication Sciences & Disorders graduate student A. Decker.

Ua94/6/1 Clinic Covid-19 Reflections - Mckay-Wilkins, A. Mckay-Wilkins

Student/Alumni Personal Papers

Reflections of Covid-19 pandemic by WKU Communication Sciences & Disorders graduate student A. McKay-Wilkins.

Ua94/6/1 Clinic Covid-19 Reflections - Gabbard, A. Gabbard

Student/Alumni Personal Papers

Reflections of Covid-19 pandemic by WKU Communication Sciences & Disorders graduate student A. Gabbard.

Ua94/6/1 Clinic Covid-19 Reflections - Rich, A. Rich

Student/Alumni Personal Papers

Reflections of Covid-19 pandemic by WKU Communication Sciences & Disorders graduate student A. Rich.

Ua94/6/1 Clinic Covid-19 Reflections - Whobrey, A. Whobrey

Student/Alumni Personal Papers

Reflections of Covid-19 pandemic by WKU Communication Sciences & Disorders graduate student A. Whobrey.

Ua94/6/1 Clinic Covid-19 Reflections - Robinson, C. Robinson

Student/Alumni Personal Papers

Reflections of Covid-19 pandemic by WKU Communication Sciences & Disorders graduate student C. Robinson.

Ua94/6/1 Clinic Covid-19 Reflections - Wheeler, H. Wheeler

Student/Alumni Personal Papers

Reflections of Covid-19 pandemic by WKU Communication Sciences & Disorders graduate student H. Wheeler.

Ua94/6/1 Clinic Covid-19 Reflections - Barnes, K. Barnes

Student/Alumni Personal Papers

Reflections of Covid-19 pandemic by WKU Communication Sciences & Disorders graduate student K. Barnes.

Ua94/6/1 Clinic Covid-19 Reflections - Church, K. Church

Student/Alumni Personal Papers

Reflections of Covid-19 pandemic by WKU Communication Sciences & Disorders graduate student K. Church.

Ua94/6/1/ Clinic Covid-19 Reflections - Holloman, K. Holloman

Student/Alumni Personal Papers

Reflections of Covid-19 pandemic by WKU Communication Sciences & Disorders graduate student K. Holloman

Ua94/6/1 Clinic Covid-19 Reflections - Perdew, H. Perdew

Student/Alumni Personal Papers

Reflections of Covid-19 pandemic by WKU Communication Sciences & Disorders graduate student H. Perdew.

Ua94/6/1 Clinic Covid-19 Reflections - Couch, E. Couch

Student/Alumni Personal Papers

Reflections of Covid-19 pandemic by WKU Communication Sciences & Disorders graduate student E. Couch.

Ua94/6/1 Clinic Covid-19 Reflections - Thomas, K. Thomas

Student/Alumni Personal Papers

Reflections of Covid-19 pandemic by WKU Communication Sciences & Disorders graduate student K. Thomas.

Ua94/6/1 Clinic Covid-19 Reflections - Williamson, K. Williamson

Student/Alumni Personal Papers

Reflections of Covid-19 pandemic by WKU Communication Sciences & Disorders graduate student K. Williamson.

Ua94/6/1 Clinic Covid-19 Reflections - Williams, C. Williams

Student/Alumni Personal Papers

Reflections of Covid-19 pandemic by WKU Communication Sciences & Disorders graduate student C. Williams.

Ua94/6/1 Clinic Covid-19 Reflections - Gunderson, H. Gunderson

Student/Alumni Personal Papers

Reflections of Covid-19 pandemic by WKU Communication Sciences & Disorders graduate student H. Gunderson.

Ua94/6/1 Clinic Covid-19 Reflections - Wethington, L. Wethington

Student/Alumni Personal Papers

Reflections of Covid-19 pandemic by WKU Communication Sciences & Disorders graduate student L. Wethington.

Ua94/6/1 Clinic Covid-19 Reflections - Belcher, E. Belcher

Student/Alumni Personal Papers

Reflections of Covid-19 pandemic by WKU Communication Sciences & Disorders graduate student E. Belcher.

Ua94/6/1 Clinic Covid-19 Reflections - Weizapfel, M. Weizapfel

Student/Alumni Personal Papers

Reflections of Covid-19 pandemic by WKU Communication Sciences & Disorders graduate student M. Weizapfel.

Ua94/6/1 Clinic Covid-19 Reflections - Rogan, R. Rogan

Student/Alumni Personal Papers

Reflections of Covid-19 pandemic by WKU Communication Sciences & Disorders graduate student R. Rogan.

Ua94/6/1 Clinic Covid-19 Reflections - Saling, R. Saling

Student/Alumni Personal Papers

Reflections of Covid-19 pandemic by WKU Communication Sciences & Disorders graduate student R. Saling.

Ua94/6/1 Clinic Covid-19 Reflections - Smith, R. Smith

Student/Alumni Personal Papers

Reflections of Covid-19 pandemic by WKU Communication Sciences & Disorders graduate student R. Smith.