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Full-Text Articles in Dentistry
Amelioration Of Oral Mucositis Pain By Nasa Near-Infrared Light-Emitting Diodes In Bone Marrow Transplant Patients, Brian Hodgson, David Margolis, Donna E. Salzman, Dan C. Eastwood, Sergey Tarima, Lisa D. Williams, Jane E. Sande, William P. Vaughan, Harry T. Whelan
Amelioration Of Oral Mucositis Pain By Nasa Near-Infrared Light-Emitting Diodes In Bone Marrow Transplant Patients, Brian Hodgson, David Margolis, Donna E. Salzman, Dan C. Eastwood, Sergey Tarima, Lisa D. Williams, Jane E. Sande, William P. Vaughan, Harry T. Whelan
Brian D Hodgson
Purpose This study seeks to investigate the use of extra-orally applied near-infrared phototherapy for the reduction of oral pain secondary to chemotherapy- and radiation therapy-induced mucositis in adult and pediatric hematopoietic stem cell transplant (HSCT) patients. Methods Eighty HSCT patients were divided into regular (R) and low (L) risk groups, then to experimental (E) and placebo (P) groups, resulting in four groups (ER, EL, PR, PL). Experimental subjects received 670 (±10) nm gallium-aluminum-arsinide light-emitting diode device for 80 s at ∼50 mW/cm2 energy density and power exposure of 4 J/cm2. Placebo patients received the same procedures, but with a placebo …