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Full-Text Articles in Dentistry

Epithelial Interleukin-8 Responses To Oral Bacterial Biofilms, Rebecca Peyyala, Sreenatha S. Kirakodu, Lucia Novakova, Jeffrey L. Ebersole Oct 2011

Epithelial Interleukin-8 Responses To Oral Bacterial Biofilms, Rebecca Peyyala, Sreenatha S. Kirakodu, Lucia Novakova, Jeffrey L. Ebersole

Center for Oral Health Research Faculty Publications

An in vitro model of bacterial biofilms on rigid gas-permeable contact lenses (RGPLs) was developed to challenge oral epithelial cells. This novel model provided seminal data on oral biofilm-host cell interactions, and with selected bacteria, the biofilms were more effective than their planktonic counterparts at stimulating host cell responses.


Comparison Of An Ultrasonic And A Non-Ultrasonic Endodontic Irrigation Protocol: A Clinical Study, Christopher M. Beus May 2011

Comparison Of An Ultrasonic And A Non-Ultrasonic Endodontic Irrigation Protocol: A Clinical Study, Christopher M. Beus

Master's Theses

The use of irrigation as a method of rendering canals bacteria free continues to be a source of investigation. Recent data suggests that an activated irrigation protocol such as passive ultrasonic irrigation can result in decreased intracanal bacteria. In addition, studies have shown that the activation of various irrigants such as NaOCl and Chlorhexidine can increase the sum antimicrobial effect. The purpose of this randomized, double blinded, prospective in-vivo clinical study was to compare the results of a non-activated irrigation protocol (NAI) using only NaOCl 1.5% to a passive ultrasonic irrigation protocol (PUI) using NaOCl 1.5%, EDTA 17% and Chlorhexidine …


Hydrolysis Of Amelogenin By Matrix Metalloprotease-20 Accelerates Mineralization In Vitro, Vuk Uskoković, Feroz Khan, Haichuan Liu, Halina Ewa Witkowska, Li Zhu, Wu Li, Stefan Habelitz Jan 2011

Hydrolysis Of Amelogenin By Matrix Metalloprotease-20 Accelerates Mineralization In Vitro, Vuk Uskoković, Feroz Khan, Haichuan Liu, Halina Ewa Witkowska, Li Zhu, Wu Li, Stefan Habelitz

Pharmacy Faculty Articles and Research

In the following respects, tooth enamel is a unique tissue in the mammalian body: (a) it is the most mineralized and hardest tissue in it comprising up to 95 wt% of apatite; (b) its microstructure is dominated by parallel rods composed of bundles of 40 – 60 nm wide apatite crystals with aspect ratios reaching up to 1:10,000 and (c) not only does the protein matrix that gives rise to enamel guides the crystal growth, but it also conducts its own degradation and removal in parallel. Hence, when mimicking the process of amelogenesis in vitro, crystal growth has to …