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Full-Text Articles in Medicine and Health Sciences

Unlv Mental Health Initiatives: Unifying Through Innovation And Collaboration, The Lincy Institute, Unlv Practice, Behere Nv, Unlv Department Of Psychology Apr 2024

Unlv Mental Health Initiatives: Unifying Through Innovation And Collaboration, The Lincy Institute, Unlv Practice, Behere Nv, Unlv Department Of Psychology

Lincy Institute Events

Nevada persistently ranks at or near the bottom in the country for overall access to mental health services despite the need (Mental Health America, 2015-2023). UNLV faculty are developing initiatives to change this unacceptable situation. The Lincy Institute, in partnership with UNLV PRACTICE, BeHERE Nevada, and researchers from the Department of Psychology, offered a community forum showcasing three mental health initiatives harnessing faculty collaboration and innovation to drive overdue changes in Nevada’s mental-health landscape. Following the presentations policymakers engaged in open discussion with UNLV presenters and the audience. The three main initiatives showcased in this forum …


Mountain West State Health System Rankings, 2023, Julia Salangsang, Ivan Sun, Caitlin J. Saladino, William E. Brown Jr. Oct 2023

Mountain West State Health System Rankings, 2023, Julia Salangsang, Ivan Sun, Caitlin J. Saladino, William E. Brown Jr.

Health

This fact sheet presents data from the “2023 Scorecard on State Health System Performance” published by The Commonwealth Fund. The original report includes data from all 50 states and measures health system performance based on health care access, quality, use of services, costs, health disparities, reproductive care and women’s health, and health outcomes.


Chemotherapeutic Drug Resistance Associated With Differential Mirna Expression Of Mir-375 And Mir-27 Among Oral Cancer Cell Lines, Kieran Huni May 2023

Chemotherapeutic Drug Resistance Associated With Differential Mirna Expression Of Mir-375 And Mir-27 Among Oral Cancer Cell Lines, Kieran Huni

UNLV Theses, Dissertations, Professional Papers, and Capstones

Objective: Although progress has been made towards the identification of molecular profiles that influence oral cancer growth and metastasis, recent advances have suggested that non-coding microRNAs (such as miR-21, miR-27, miR-145, miR-155, miR-365, miR-375 and miR-494) may be involved in multiple aspects of chemotherapeutic responsiveness. Based upon the paucity of information regarding this phenomenon, this project will determine whether these specific microRNAs are correlated with oral cancer responsiveness to chemotherapies, including Paclitaxel, Cisplatin and Fluorouracil (5FU).Methods: Commercially available and well-characterized oral squamous cell carcinoma cell lines (SCC4, SCC9, SCC15, SCC25 and CAL27) were used for this study. Experimental 96-well assays …


A Pilot Program To Inform High School Students About Allied Healthcare Professions, Nhu Mac May 2023

A Pilot Program To Inform High School Students About Allied Healthcare Professions, Nhu Mac

UNLV Theses, Dissertations, Professional Papers, and Capstones

The literature revealed the lack of diversity in the workforce, limited recruiting and retention methods, and lack of exposure to these professions as the contributions to the shortage and demand for the profession of occupational therapy (OT), physical therapy (PT), and speech- language pathology (SLP). As a result, the fourteen-week program to inform high school students about OT, PT, and SLP roles in the community and public health was implemented at Desert Pines High School in Clark County School District (CCSD) to see if it would influence their perceived attitudes, knowledge, beliefs, and the likelihood of pursuing these careers. Using …


Oral Prevalence Of Akkermancia Muciniphila Among Pediatric And Adult Orthodontic And Non-Orthodontic Patients, Ching Shen May 2023

Oral Prevalence Of Akkermancia Muciniphila Among Pediatric And Adult Orthodontic And Non-Orthodontic Patients, Ching Shen

UNLV Theses, Dissertations, Professional Papers, and Capstones

Akkermansia muciniphila (AM) is one of many highly abundant intestinal microbes that influences homeostasis and metabolic disorders and may also play a role in oral disorders. However, there is little evidence regarding the oral prevalence of this organism. Based upon this lack of evidence, the primary goal of this project is to survey an existing saliva repository to determine the overall prevalence of this organism and any associations with demographic or patient characteristics (age, sex, body mass index, race/ethnicity, orthodontic therapy). Using an approved protocol, a total n = 141 pediatric samples from an existing saliva repository were screened using …


Dental Pulp Stem Cell Differentiation Potential Of Bmp-2 And Bmp-4, David Li May 2023

Dental Pulp Stem Cell Differentiation Potential Of Bmp-2 And Bmp-4, David Li

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction: Many studies are now evaluating the potential for dental pulp stem cells (DPSC) to assist with more complex and biotechnology applications, such as facilitating and promoting osseointegration following dental implants. However, the effects of factors that may control osseointegration and bone repair using DPSC including bone morphogenic proteins (BMP-2, BMP-4) are not yet well understood.Objective: Based upon this lack of evidence, the primary goal of this project is to evaluate the potential effects of BMPs (alone or in combination with other growth factors) to induce factors associated with osteogenesis. Methods: DPSC isolates from an existing repository (n = 13) …


Leveraging Simulation To Understand Nursing Student Learning In Technologically Complex Environment, Deborah Rojas May 2023

Leveraging Simulation To Understand Nursing Student Learning In Technologically Complex Environment, Deborah Rojas

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction The adoption of simulation technologies in schools of nursing has increased significantly over the last 5 years. Results regarding the use of simulation technology have been positive. The use of simulation technologies has been developed to include complex nursing situations that resemble real clinical settings. Research has demonstrated that memory recall is better in an environment that is the same or similar to the environment in which the learning took place (Krokos et al., 2018). For this reason, educators have used simulation technologies to create realistic environments where students can learn. However, learning outcomes in simulations are affected by …


Differential Effects Of Extracellular Matrix Glycoproteins Fibronectin And Laminin-5 On Dental Pulp Stem Cell Phenotypes And Responsiveness, Hyungbin Lee May 2023

Differential Effects Of Extracellular Matrix Glycoproteins Fibronectin And Laminin-5 On Dental Pulp Stem Cell Phenotypes And Responsiveness, Hyungbin Lee

UNLV Theses, Dissertations, Professional Papers, and Capstones

Dental pulp stem cells (DPSCs) are mesenchymal stem cells (MSCs) with the potential to differentiate in a limited number of other tissue types. Some evidence has suggested the modulation of DPSC growth may be mediated, in part, by exogenous extracellular matrix (ECM) glycoproteins, including fibronectin (FN) and laminin-5 (LN5). Although preliminary research suggests that some ECM glycoproteins may work as functional biomaterials to modulate DPSC growth responses, the primary goal of this project is to determine the specific effects of FN and LN5 on DPSC growth and viability.Using an existing DPSC repository, n = 16 DPSC isolates were cultured and …


Socio-Demographic, Maternal, And Infant Characteristics Associated With Pacifier Use Among Six-Months Old Infants In Clark County, Nevada, Kaelia Lynn Saniatan, Smriti Neupane, Chad L. Cross, Gabriela S. Buccini Apr 2023

Socio-Demographic, Maternal, And Infant Characteristics Associated With Pacifier Use Among Six-Months Old Infants In Clark County, Nevada, Kaelia Lynn Saniatan, Smriti Neupane, Chad L. Cross, Gabriela S. Buccini

Epidemiology & Biostatistics Faculty Publications

Background

Pacifier use can interfere with nurturing care practices such as breastfeeding, soothing, and sleeping. Due to contradicting beliefs, recommendations, and the high frequency of pacifier use, understanding its associations may support shaping equitable public health recommendations. This study explored the socio-demographic, maternal, and infant characteristics associated with pacifier use among six-months old infants in Clark County, Nevada.

Method

Cross-sectional survey was conducted in 2021 with a sample of mothers (n = 276) of infants under six months old in Clark County, Nevada. Participants were recruited through advertisements in birth, lactation, pediatric care centers, and social media. We used binomial …


Advancing Health Equity In The Us Military, James D. Mancuso, John Young, Jennifer Rusiecki, Shauna Stahlman, Natasha Schvey, Toya Randolph, Candy Wilson, Catherine Witkop, Patrick Hyde, Althea Green, Patcho Santiago, Donald Shell, Tracy Sbrocco Mar 2023

Advancing Health Equity In The Us Military, James D. Mancuso, John Young, Jennifer Rusiecki, Shauna Stahlman, Natasha Schvey, Toya Randolph, Candy Wilson, Catherine Witkop, Patrick Hyde, Althea Green, Patcho Santiago, Donald Shell, Tracy Sbrocco

Journal of Health Disparities Research and Practice

Eliminating health disparities and achieving health equity are central to US national health objectives and the Military Health System’s “quadruple aim,” which has readiness as its core aim. Because military service members enjoy universal eligibility for health care, it is sometimes assumed that health disparities do not exist in the Department of Defense (DoD). However, while some studies have shown that disparities have been attenuated or eliminated in the DoD, others suggest that significant disparities remain. Reasons these disparities may remain include that universal eligibility for care does not necessarily result in equal to access to care, and that equal …


Self-Reported Covid-19 Diagnosis And Severity And Its Association With Utilization Of And Delays In Needed Medical Care, Mohammad Hesam Alavi Dec 2022

Self-Reported Covid-19 Diagnosis And Severity And Its Association With Utilization Of And Delays In Needed Medical Care, Mohammad Hesam Alavi

UNLV Theses, Dissertations, Professional Papers, and Capstones

Covid-19, caused by the virus SARS-CoV-2, was declared a pandemic by the World Health Organization (WHO) on March 11, 2020. The pandemic-related disruptions and the pursuant lockdowns have adversely impacted every aspect of people’s lives including access to medical care, cancer care, preventive medicine, mental health, and dental care in an already imperfect healthcare system in the US. This study utilized the 2020 self-reported data from quarters 3 and 4 of the National Health Interview Survey, a cross-sectional interview survey by the Centers for Disease Control and Prevention, to determine the possible association of self-reported COVID diagnosis, test positivity, and …


Predicting Flossing Through The Application Of The Multi-Theory Model (Mtm) Of Health Behavior Change Among Minority Adolescents In The United States, Manoj Sharma, Kavita Batra, Ching-Chen Chen, Chia-Liang Dai, Ravi Batra, David Cappelli Nov 2022

Predicting Flossing Through The Application Of The Multi-Theory Model (Mtm) Of Health Behavior Change Among Minority Adolescents In The United States, Manoj Sharma, Kavita Batra, Ching-Chen Chen, Chia-Liang Dai, Ravi Batra, David Cappelli

Social & Behavioral Health Faculty Publications

Adolescents from minority groups are particularly susceptible to poor oral hygiene behaviors, including lack of daily flossing. This cross-sectional study aimed to conduct an exploratory behavioral research to identify evidence-based (theory-based) approaches to promote flossing behavior among African American/Black and Latinx/Hispanic (minority) adolescents. A 39-item psychometrically valid web-based questionnaire was used to collect responses from a nationwide sample of minority adolescents aged 10–17 years residing in the United States. The data were analyzed using bivariate and multivariate statistical methods. Of 520 minority adolescents (260 African American/Black and 260 Latinx/Hispanic adolescents), the proportion of flossing was nearly equally split in the …


Executive Summary: Driving The Southern Nevada Health Economy Forward, Tripp Umbach Oct 2022

Executive Summary: Driving The Southern Nevada Health Economy Forward, Tripp Umbach

Policy Briefs and Reports

The University of Nevada, Las Vegas (UNLV) plans to develop an integrated academic health center within the Las Vegas Medical District (LVMD).1 The academic health center includes UNLV’s five health science schools and mental and behavioral health, which is distributed among several colleges (medicine, liberal arts, urban affairs, and education) in the university. University Medical Center (UMC), a major teaching hospital, will also be an important driver of the academic health center. For the purposes of this report, UNLV’s medical and health science entities along with UMC are referred to collectively as the UNLV Academic Health Center.


Driving The Southern Nevada Health Economy Forward: Benefits Of A Transformational Unlv Academic Health Center, Tripp Umbach Oct 2022

Driving The Southern Nevada Health Economy Forward: Benefits Of A Transformational Unlv Academic Health Center, Tripp Umbach

Policy Briefs and Reports

The University of Nevada, Las Vegas (UNLV) plans to develop an integrated academic health center within the Las Vegas Medical District (LVMD). The academic health center includes UNLV’s five health science schools and mental and behavioral health, which is distributed among several colleges (medicine, liberal arts, urban affairs, and education) in the university. University Medical Center (UMC), a major teaching hospital, will also be an important driver of the academic health center. For the purposes of this report, UNLV’s medical and health science entities along with UMC are referred to collectively as the UNLV Academic Health Center. Additional academic health …


Assessing The Compliance Of Dental Clinicians Towards Regulatory Infection Control Guidelines Using A Newly Developed Survey Tool: A Pilot Cross-Sectional Study In India, Pragati Kaurani, Kavita Batra, Himangini Rathore Hooja, N. Gopi Chander, Anamitra Bhowmick, Suraj Arora, Suheel Manzoor Baba, Shafait Ullah Khateeb, Anshad M. Abdulla, Vishakha Grover, Priyanka Saluja Sep 2022

Assessing The Compliance Of Dental Clinicians Towards Regulatory Infection Control Guidelines Using A Newly Developed Survey Tool: A Pilot Cross-Sectional Study In India, Pragati Kaurani, Kavita Batra, Himangini Rathore Hooja, N. Gopi Chander, Anamitra Bhowmick, Suraj Arora, Suheel Manzoor Baba, Shafait Ullah Khateeb, Anshad M. Abdulla, Vishakha Grover, Priyanka Saluja

School of Medicine Faculty Publications

Adherence to the dental practice regulatory guidelines instituted during the COVID- 19 pandemic is essential to minimize the transmission of SARS-CoV-2 strains. Given the lack of a valid and reliable survey tool to assess the adherence to dental practice guidelines, this study aims to develop, validate, and test a survey tool on a pilot sample of dental clinicians practicing in India. A survey tool was developed/validated through a sequential phasic approach: Phase Ideveloping survey using conceptual and literature framework; Phase II: ascertaining its validity and reliability; Phase III: pilot testing; and Phase IV: assessing construct validity by exploratory factor analysis …


Motherhood Together: Effects Of An Adapted Prenatal Curriculum On Mother And Infant Outcomes, Rebecca Lovan, Clare Brown, Keneshia Bryant-Moore, Leslie Mccormack, Nicole Ward, Shannon Kalkwarf, Beverly English, Elizabeth Riley Sep 2022

Motherhood Together: Effects Of An Adapted Prenatal Curriculum On Mother And Infant Outcomes, Rebecca Lovan, Clare Brown, Keneshia Bryant-Moore, Leslie Mccormack, Nicole Ward, Shannon Kalkwarf, Beverly English, Elizabeth Riley

Journal of Health Disparities Research and Practice

Background: Research shows that pregnant women experiencing housing insecurity are more likely to face barriers to prenatal care that can lead to negative health outcomes for both mother and infant. Previous studies have also shown that prenatal education programs provide pregnant mothers with the knowledge and resources that increase the likelihood of positive health outcomes. An interprofessional healthcare team in Central Arkansas modified an existing prenatal education program to create Motherhood Together, a program specifically tailored for pregnant women facing house insecurity.

Methods: The purpose of this initial evaluation of the Motherhood Together program was to identify the feasibility of …


Health Rankings: Mountain West States, 2021, Hira Ahmed, Sofia Takhtadjian, Olivia K. Cheche, Elia Del Carmen Solano-Patricio, Caitlin J. Saladino, William E. Brown Jr. Aug 2022

Health Rankings: Mountain West States, 2021, Hira Ahmed, Sofia Takhtadjian, Olivia K. Cheche, Elia Del Carmen Solano-Patricio, Caitlin J. Saladino, William E. Brown Jr.

Health

Using data from the United Health Foundation’s “America’s Health Rankings Annual Report 2021,” this fact sheet compares various measures of health in the Mountain West using data from 2014 to 2021. The original report includes data on the five determinants of health including social and economic factors, physical environment, clinical care, behaviors, and health outcomes. This fact sheet examines health metrics for the Mountain West states of Arizona, Colorado, Nevada, New Mexico, and Utah.


A Feasibility Study To Identify If The Induction Of The Relationship Based Care Program Enhance The Caring Skills Of Registered Nurses?, Jennifer Millet Aug 2022

A Feasibility Study To Identify If The Induction Of The Relationship Based Care Program Enhance The Caring Skills Of Registered Nurses?, Jennifer Millet

UNLV Theses, Dissertations, Professional Papers, and Capstones

The purpose of this Doctor of Nursing Practice project was to educate the Registered Nurses (RNs) to implement the Relationship Based Care (RBC) model and Jean Watson’s Theory of Human Caring principles into their practice. The model and principles were put into practice by the RNs, followed by examining the RNs perception and practices of caring and confidence skills had improved after the intervention. The mission of this project was to promote quality outcomes and patient satisfaction through caring relationships. Strengthening these relationships will help the caregiver experience the essence of care and be able to better connect to another …


Assessing Covid-19 Booster Hesitancy And Its Correlates: An Early Evidence From India, Geetanjali C. Achrekar, Kavita Batra, Yashashri Urankar, Ravi Batra, Naved Iqbal, Sabiha A. Choudhury, Deepti Hooda, Roohi Khan, Suraj Arora, Aditi Singh, Francesco Chirico, Manoj Sharma Jun 2022

Assessing Covid-19 Booster Hesitancy And Its Correlates: An Early Evidence From India, Geetanjali C. Achrekar, Kavita Batra, Yashashri Urankar, Ravi Batra, Naved Iqbal, Sabiha A. Choudhury, Deepti Hooda, Roohi Khan, Suraj Arora, Aditi Singh, Francesco Chirico, Manoj Sharma

School of Medicine Faculty Publications

The emergence of SARS-CoV-2 mutants, waning immunity, and breakthrough infections prompted the use of booster doses of the COVID-19 vaccine to fight against the pandemic. India started booster doses in January 2022 and it is critical to determine the intention of booster dose uptake and its correlates. Therefore, the current cross-sectional study aimed to investigate booster dose acceptability and associated predictors among the Indian population. A convenience sampling technique was utilized to recruit a sample of 687 Indian residents. A 55-item psychometric validated survey tool was used to assess booster dose acceptability, vaccine literacy and vaccine confidence. Univariate, bivariate, and …


Parental Education On Human Papillomavirus Vaccination, Marguarette J. Suprien May 2022

Parental Education On Human Papillomavirus Vaccination, Marguarette J. Suprien

UNLV Theses, Dissertations, Professional Papers, and Capstones

The human papillomavirus (HPV) is a worldwide condition that produces several diseases, including cervical, anogenital, and oral cancer, among others (Fishman et al., 2014). The Center for Disease Control and Prevention (CDC; 2016a) stated that HPV is among the most reported sexually transmitted diseases in the United States. Over 150 viruses are associated with HPV, and 40 types of the virus can be spread via sexual contact, including vaginal, oral, and anal sex (CDC, 2016; CDC, 2016b; CDC, 2016c). Evidence shows that approximately 79 million individuals are infected in the United States, and 14 million Americans are infected with the …


Comparative Effects Of High-Intensity Interval Warm-Up Exercise And Bronchodilator On Exercise-Induced Bronchoconstriction In Children With Mild Asthma, Michael Wong May 2022

Comparative Effects Of High-Intensity Interval Warm-Up Exercise And Bronchodilator On Exercise-Induced Bronchoconstriction In Children With Mild Asthma, Michael Wong

UNLV Theses, Dissertations, Professional Papers, and Capstones

Purpose: The troubling link between obesity and asthma in children, along with greater associated detrimental health effects, warrants investigation to better understand the mechanisms driving this relationship as well as its consequences, especially during exercise. Bronchodilators and interval warm-up exercises are recommended by the American Thoracic Society to prevent exercise-induced bronchoconstriction (EIB). Whether interval warm-up exercise can prevent EIB to the same extent as bronchodilators in asthmatic children is unknown but clinically important. Therefore, the first purpose of this study is to investigate the effects of obesity on pulmonary function, exercise tolerance, and exercise-induced bronchoconstriction in asthmatic children. The second …


Essential Tools For Sustainability Of A Student-Led, Pro-Bono Back School, Cory Brown, Rosalie Gutierrez, Jennifer Montes, Rondale Scruggs May 2022

Essential Tools For Sustainability Of A Student-Led, Pro-Bono Back School, Cory Brown, Rosalie Gutierrez, Jennifer Montes, Rondale Scruggs

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background: In 2018, University of Nevada Las Vegas Doctor of Physical Therapy (DPT) students and faculty, in cooperation with a community partner, created a student-led pro bono Back School to address a gap in healthcare for underinsured individuals with low back pain in Southern Nevada. To support the sustainability of the Back School, the authors of this paper set out to develop a student club to recruit and train DPT students to volunteer in the program using a specifically designed electronic training manual. Overall, the aim was to encourage students to join the new club's leadership team to prepare future …


Physical Therapy Alumni Rural Employment Assessment, Karen Aleyda Santos, Nikkita Jacob Crozier May 2022

Physical Therapy Alumni Rural Employment Assessment, Karen Aleyda Santos, Nikkita Jacob Crozier

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction and Purpose: The University of Nevada, Las Vegas Doctor of Physical Therapy program (UNLVPT) encourages rural and underserved employment by requiring students to complete one clinical experience in either a rural or underserved setting. Students who participate in rural clinical experiences may be more likely to practice in rural settings. UNLVPT also assesses rural interest level during each student’s education. The purpose of this study was to determine if relationship exists between students’ pre- or post-clinical experience rural interest level and their practice location within the first two years after graduation. We hypothesized that an interest in rural practice …


Utilizing Emotional Intelligence To Cultivate Occupational Therapy Students' Leadership Skills, Talina Minasian May 2022

Utilizing Emotional Intelligence To Cultivate Occupational Therapy Students' Leadership Skills, Talina Minasian

UNLV Theses, Dissertations, Professional Papers, and Capstones

Emotional intelligence (EI) education is a crucial component to facilitating professional and leadership skills. Strengthening emotional competence through training and education can support clinician success. The healthcare sector is complex and presents many challenges and emotionally demanding circumstances. Sharpening emotional intelligence skills can provide tools for students, practitioners, and leaders to effectively respond and rise above difficult situations. There is a strong need for healthcare programs to supplement their curriculums with EI learning.

This doctoral project explored the benefits and impact of integrating emotional intelligence education into a leadership course for entry-level occupational therapy (OT) students. Using current literature, a …


Family-Centered Psychosocial Care For Pediatric Oncology Patients, Jessica W. Casey May 2022

Family-Centered Psychosocial Care For Pediatric Oncology Patients, Jessica W. Casey

UNLV Theses, Dissertations, Professional Papers, and Capstones

Psychosocial conditions are prevalent in pediatric oncology patients (Kahalley et al., 2013). Family and social support are essential aspects of a patient's health care outcomes (Merck & McElfresh, 2019). Anxiety and depression are common in pediatric oncology patients due to trauma during treatment (Pao & Kazak, 2015). These patients also can have preexisting developmental or behavioral conditions before starting treatment. Treatment side effects can also cause cognitive and behavioral changes (Nixon, 2014b). Nurses should be knowledgeable and confident in their ability to care for patients' psychosocial health and development. The purpose of this Doctor of Nursing Practice (DNP) project is …


Is Dietary Teaching Via Telehealth Effective In Lowering Hgba1c In Adult Patients With Prediabetes Or Type 2 Diabetes?, Mia Mccallum-Crawford May 2022

Is Dietary Teaching Via Telehealth Effective In Lowering Hgba1c In Adult Patients With Prediabetes Or Type 2 Diabetes?, Mia Mccallum-Crawford

UNLV Theses, Dissertations, Professional Papers, and Capstones

Prediabetes and Type 2 diabetes mellitus (T2DM) are two common conditions diagnosed in the primary care setting. Both conditions benefit from a healthy lifestyle, managing blood sugar levels, and getting diabetes self-management education and support (DSMES). Within the past two decades, the healthcare community in the US has witnessed a substantial rise in diabetes among adults. Overall, the self-management of diabetes continues to worsen nationally. The purpose of this project is to improve patients’ self-management of both Prediabetes and T2DM through nutrition and show how nutritional counseling via telehealth provided by a nurse practitioner can improve HgbA1C values over 3 …


Comparative Expression Of Exosome-Derived Dental Pulp Stem Cell (Dpsc) Microrna, Matthew Hunsaker May 2022

Comparative Expression Of Exosome-Derived Dental Pulp Stem Cell (Dpsc) Microrna, Matthew Hunsaker

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction: Dental pulp stem cells (DPSC) are pluripotent stem cells capable of differentiating into several tissue types. Several studies have demonstrated DPSC can be extracted from deciduous and permanent teeth, including third molars (wisdom teeth) - however, much less is known regarding the factors that determine and regulate pluripotency and differentiation responsiveness among these harvested DPSC. Recent evidence has suggested small, non-coding microRNAs mediate (in part) differentiation and self-renewal among some stromal and hematopoetic stem cells, although much remains to be discovered regarding microRNA regulation of DPSC phenotypes. Based upon this information, the overall goal of this study was to …


Regional Health Benefits Of The Nevada Renewable Energy Initiative, Alireza Rezaee May 2022

Regional Health Benefits Of The Nevada Renewable Energy Initiative, Alireza Rezaee

UNLV Theses, Dissertations, Professional Papers, and Capstones

In recent years, there have been tremendous efforts to replace fossil fuels with renewable energy to mitigate emissions of greenhouse gases and air pollutants in the United States. Nevada was among the first states that established the renewable portfolio standards (RPS), requiring a certain percentage of electricity sold to the customers for consumption coming from renewable resources. The recent Nevada Senate Bill 358, signed by Nevada’s Governor in 2019, set a target that by 2030 not less than 50% of electricity sold in Nevada should come from renewable resources. This research investigates how this Bill could provide health benefits for …


Differential Expression Of Cellular And Exosomal Microrna Isolated From Oral Cancer Cells And Their Resistance To Chemotherapy, Brady Petersen May 2022

Differential Expression Of Cellular And Exosomal Microrna Isolated From Oral Cancer Cells And Their Resistance To Chemotherapy, Brady Petersen

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction: MicroRNAs are abundant small non-coding RNA with a variety of known functions, including transcriptional activation and inhibition. Recent evidence has suggested that microRNA expression may influence the responsiveness of some cancers to chemotherapy, including liver and lung cancers. Some evidence has now suggested that specific microRNAs, such as miR-21, miR-155, and miR-375, may influence oral cancer responsiveness to chemotherapy – although much remains to be discovered.

Objective: Based upon the lack of evidence in this area, the primary objective of this study was to evaluate microRNA expression and responsiveness among oral cancers.

Methods: Five commercially available oral cancer cell …


Assessment Of Oral Human Papillomavirus In Pediatric And Adult Patients Within A Multi-Ethnic Clinic Population, Melissa Kornhaber May 2022

Assessment Of Oral Human Papillomavirus In Pediatric And Adult Patients Within A Multi-Ethnic Clinic Population, Melissa Kornhaber

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction: Human papillomavirus (HPV) encompasses a large family of oncogenic viruses responsible for increasing rates of both cervical and oral cancer, particularly among minority and low-income populations. Although this represents an increasingly significant public health risk, few studies have screened for oral HPV within Nevada. Based upon this information, the primary objective of this study was to provide a temporal analysis of oral HPV screening among a primarily low-income, minority patient population.

Methods: This retrospective analysis was reviewed and approved by the Institutional Review Board (IRB). In brief, unstimulated saliva samples were previously obtained from clinical patient volunteers that provided …