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Full-Text Articles in Medicine and Health Sciences
The Use And Effectiveness Of Coping Mechanisms In Parents Of Children With Type 1 Diabetes, J. Shelley Dornan
The Use And Effectiveness Of Coping Mechanisms In Parents Of Children With Type 1 Diabetes, J. Shelley Dornan
MSN Research Projects
Coping with the responsibility of raising a child with diabetes is a serious challenge for parents. The methods parents use to cope can influence the child's future outcome. Therefore, the purpose of this descriptive study was to identify the use and effectiveness of coping mechanisms among parents of children with Type 1 diabetes. A convenience sample of 4 0 parents with a diabetic child was obtained from a diabetic support group and a pediatric endocrinology clinic in the Southeastern United States. Data were collected using the Jalowiec Coping Scale and the researcher-designed Demographic Survey. Analysis of data was conducted using …
Demographics At Diagnosis Of Children With Type 2 Diabetes, Marcia Fleming Hammett
Demographics At Diagnosis Of Children With Type 2 Diabetes, Marcia Fleming Hammett
MSN Research Projects
Since 1991 the diagnosis of Type 2 diabetes in children has increased at an alarming rate. Researchers have identified some common descriptors which may be predictive of early assessment and intervention for this population. Further validation of established descriptors and identification of other descriptors are needed. In this retrospective descriptive study, one research question guided the study: What are the demographic characteristics of children with Type 2 diabetes at the time of diagnosis? The Neuman Systems Model (198 9) provided the theoretical framework. Data were collected using the Hammett Chart Survey with 3 9 review variables. Charts from three endocrinology …
Role Of Protein Kinase C In The Translational Regulation Of Lipoprotein Lipase In Adipocytes, Gouri Ranganathan, Rami Kaakaji, Philip A. Kern
Role Of Protein Kinase C In The Translational Regulation Of Lipoprotein Lipase In Adipocytes, Gouri Ranganathan, Rami Kaakaji, Philip A. Kern
Clinical and Translational Science Faculty Publications
The hypertriglyceridemia of diabetes is accompanied by decreased lipoprotein lipase (LPL) activity in adipocytes. Although the mechanism for decreased LPL is not known, elevated glucose is known to increase diacylglycerol, which activates protein kinase C (PKC). To determine whether PKC is involved in the regulation of LPL, we studied the effect of 12-O-tetradecanoyl phorbol 13-acetate (TPA) on adipocytes. LPL activity was inhibited when TPA was added to cultures of 3T3-F442A and rat primary adipocytes. The inhibitory effect of TPA on LPL activity was observed after 6 h of treatment, and was observed at a concentration of 6 nM. …
The Footwear Suitability Scale: A Measure Of Shoe-Fit For People With Diabetes, Susan Nancarrow
The Footwear Suitability Scale: A Measure Of Shoe-Fit For People With Diabetes, Susan Nancarrow
Susan Nancarrow
Footwear has been found to be a precipitating cause of injury leading to lower extremity ulceration and amputation in people with diabetes. This study determined footwear suitability in one hundred diabetic outpatients in south-east Queensland using ten criteria including the fit of the shoe and the ability of the shoe to prevent injury to the foot. Footwear suitability was analysed in the context of the price, place of purchase and quality of shoes purchased. In this study, overall shoe quality was poor. Over one quarter of all participants and one third of participants with peripheral neuropathy wore shoes that caused …
Effects Of Dietary Salt On Blood Pressure, Heartrate, Extracellular Fluid Volume And Glomerularfiltration Rate In Diabetic Rats, Besi̇m Özaykan, Ayşe Doğan
Effects Of Dietary Salt On Blood Pressure, Heartrate, Extracellular Fluid Volume And Glomerularfiltration Rate In Diabetic Rats, Besi̇m Özaykan, Ayşe Doğan
Turkish Journal of Medical Sciences
In the present study, we aimed to investigate the effects of dietary salt restriction and loading on extracellular fluid volume (ECFV), blood pressure (BP), heart rate (HR), glomerular filtration rate (GFR) and renal hypertrophy in diabetic rats. Diabetes was induced by injection of streptozotocin (STZ, 65 mg/kg, iv) into male Wistar rats. Four groups were formed: a) the diabetic rats given a standard rat diet (DC), b) the diabetic rats given a high-salt diet (DHS), c) the diabetic rats given a low-salt diet (DLS), d) the nondiabetic rats given a standard rat diet (C). Salt loading and salt restriction were …