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Articles 1 - 9 of 9
Full-Text Articles in Medicine and Health Sciences
Apolipoprotein A-I Mimetic Peptide L-4f Prevents Myocardial And Coronary Dysfunction In Diabetic Mice, C. Vecoli, J. Cao, D. Neglia, K. Inoue, Komal Sodhi, L. Vanella, K. K. Gabrielson, D. Bedja, N. Paolocci, A. L'Abbate, Nader G. Abraham
Apolipoprotein A-I Mimetic Peptide L-4f Prevents Myocardial And Coronary Dysfunction In Diabetic Mice, C. Vecoli, J. Cao, D. Neglia, K. Inoue, Komal Sodhi, L. Vanella, K. K. Gabrielson, D. Bedja, N. Paolocci, A. L'Abbate, Nader G. Abraham
Nader G. Abraham
Diabetes is a major health problem associated with adverse cardiovascular outcomes. The apolipoprotein A-I mimetic peptide L-4F is a putative anti-diabetic drug, has antioxidant and anti-inflammatory proprieties and improves endothelial function. In obese mice L-4F increases adiponectin levels, improving insulin sensitivity and reducing visceral adiposity. We hypothesized that the pleiotropic actions of L-4F can prevent heart and coronary dysfunction in a mouse model of genetically induced Type II diabetes. We treated db/db mice with either L-4F or vehicle for 8 weeks. Trans-thoracic echocardiography was performed; thereafter, isolated hearts were subjected to ischemia/reperfusion (IR). Glucose, insulin, adiponectin, and pro-inflammatory cytokines (IL-1β, …
Race/Ethnicity-, Gender- And Age-Specific Differences In Micronutrient Intakes Of Us Adults With And Without Diabetes, Joan Vaccaro, Fatma Huffman
Race/Ethnicity-, Gender- And Age-Specific Differences In Micronutrient Intakes Of Us Adults With And Without Diabetes, Joan Vaccaro, Fatma Huffman
Joan A. Vaccaro
Race/ethnicity-, gender- and age-specific differences in dietary micronutrient intakes of US adults ≥ 21 years were assessed from National Health and Nutrition Examination Survey, 2007–2008. The participants included Black non-Hispanics, Mexican-American and White non-Hispanics who signed an informed consent form for the interview and who completed the in-person 24-h recall. Micronutrient intakes were based on the Institute of Medicines' classifications of recommended dietary allowances specific for age and gender. Likelihood of many micronutrient insufficiencies was associated with being female, over 65 years, having diabetes and minority status. Younger and female adults had a greater likelihood of iron insufficiency than male …
Postpartum Screening For Diabetes Among Medicaid-Eligible South Carolina Women With Gestational Diabetes, Nathan Hale, Janice Probst, Jihong Liu, Amy Martin, Kevin Bennett, Saundra Glover
Postpartum Screening For Diabetes Among Medicaid-Eligible South Carolina Women With Gestational Diabetes, Nathan Hale, Janice Probst, Jihong Liu, Amy Martin, Kevin Bennett, Saundra Glover
Jihong Liu
No abstract provided.
The Relationship Between Coping Styles In Response To Unfair Treatment And Understanding Of Diabetes Self-Care, Michelle Dyke, Yendelela Cuffee, Jewell Halanych, Richard Mcmanus, Carol Curtin, Jeroan Allison
The Relationship Between Coping Styles In Response To Unfair Treatment And Understanding Of Diabetes Self-Care, Michelle Dyke, Yendelela Cuffee, Jewell Halanych, Richard Mcmanus, Carol Curtin, Jeroan Allison
Richard H. McManus
Purpose This study examined the relationship between coping style and understanding of diabetes self-care among African American and white elders in a southern Medicare-managed care plan. Methods Participants were identified through a diabetes-related pharmacy claim or ICD-9 code and completed a computer-assisted telephone survey in 2006-2007. Understanding of diabetes self-care was assessed using the Diabetes Care Profile Understanding (DCP-U) scale. Coping styles were classified as active (talk about it/take action) or passive (keep it to yourself). Linear regression was used to estimate the associations between coping style with the DCP-U, adjusting for age, sex, education, and comorbidities. Based on the …
Age At Diagnosis Of Diabetes In Appalachia, Lawrence Barker, Robert Gerzoff, Richard Crespo, Molly Shrewsberry
Age At Diagnosis Of Diabetes In Appalachia, Lawrence Barker, Robert Gerzoff, Richard Crespo, Molly Shrewsberry
Richard Crespo
Background Appalachia is a region of the United States noted for the poverty and poor health outcomes of its residents. Residents of the poorest Appalachian counties have a high prevalence of diabetes and risk factors (obesity, low income, low education, etc.) for type 2 diabetes. However, diabetes prevalence exceeds what these risk factors alone explain. Based on this, the history of poor health outcomes in Appalachia, and personally observed high rates of childhood obesity and lack of concern about prediabetes, we speculated that people in Appalachia with diagnosed diabetes might tend to be diagnosed younger than their non-Appalachian counterparts. Methods …
Residence In A Distressed County In Appalachia As A Risk Factor For Diabetes, Behavioral Risk Factor Surveillance System, 2006-2007, Lawrence Barker, Richard Crespo, Robert Gerzoff, Sharon Denham, Molly Shrewsberry, Darrlyn Cornelius-Averhart
Residence In A Distressed County In Appalachia As A Risk Factor For Diabetes, Behavioral Risk Factor Surveillance System, 2006-2007, Lawrence Barker, Richard Crespo, Robert Gerzoff, Sharon Denham, Molly Shrewsberry, Darrlyn Cornelius-Averhart
Richard Crespo
Introduction We compared the risk of diabetes for residents of Appalachian counties to that of residents of non-Appalachian counties after controlling for selected risk factors in states containing at least 1 Appalachian county. Methods We combined Behavioral Risk Factor Surveillance System data from 2006 and 2007 and conducted a logistic regression analysis, with self-reported diabetes as the dependent variable. We considered county of residence (5 classifications for Appalachian counties, based on economic development, and 1 for non-Appalachian counties), age, sex, race/ethnicity, education, household income, smoking status, physical activity level, and obesity to be independent variables. The classification “distressed” refers to …
Does Hero Always Help? Differences In Nutrient Intake Among Obese Subjects With And Without Type 2 Diabetes Mellitus Prior To Dietary Intervention, Sze Yen Tan, Lynda Gillen, Marijka Batterham, Xu-Feng Huang, Cassandra Quick, Yasmine Probst, Serina Faraji, Linda Tapsell
Does Hero Always Help? Differences In Nutrient Intake Among Obese Subjects With And Without Type 2 Diabetes Mellitus Prior To Dietary Intervention, Sze Yen Tan, Lynda Gillen, Marijka Batterham, Xu-Feng Huang, Cassandra Quick, Yasmine Probst, Serina Faraji, Linda Tapsell
Xu-Feng Huang
No abstract provided.
Hypertension And Antihypertensive Therapy As Risk Factors For Type 2 Diabetes Mellitus, Todd Gress, Javier Nieto, Eyal Shahar, Marion Wofford, Frederick Brancati
Hypertension And Antihypertensive Therapy As Risk Factors For Type 2 Diabetes Mellitus, Todd Gress, Javier Nieto, Eyal Shahar, Marion Wofford, Frederick Brancati
Todd W. Gress
Background Previous research has suggested that thiazide diuretics and beta-blockers may promote the development of type 2 diabetes mellitus. However, the results of these studies have been inconsistent, and many studies have been limited by inadequate data on outcomes and by potential confounding. Methods We conducted a prospective study of 12,550 adults 45 to 64 years old who did not have diabetes. An extensive health evaluation conducted at base line included assessment of medication use and measurement of blood pressure with a random-zero sphygmomanometer. The incidence of new cases of diabetes was assessed after three years and after six years …
Diabetic Rates And Mice Are Resistent To Porcine And Human Insulin: Flawed Experimental Models For Testing Islet Xenograft, A. Pepper, C. Gall, D. Mazzuca, C.W.J. Melling, D. White
Diabetic Rates And Mice Are Resistent To Porcine And Human Insulin: Flawed Experimental Models For Testing Islet Xenograft, A. Pepper, C. Gall, D. Mazzuca, C.W.J. Melling, D. White
Jamie Melling
BACKGROUND: Islet transplantation is potentially a promising therapy for the restoration of carbohydrate control to diabetic patients. However, the global application of islet transplantation requires a ubiquitous source of beta cells. The xenotransplantation of porcine islets would provide such a source. Success in porcine islet xenografting has been achieved in diabetic primates. However, there are few reports of reversal of diabetes with porcine islet xenografts in rodent models of diabetes, relative to the number of successful rodent experiments performed as allografts. Here we report for the first time the inability of porcine (and human) insulin to control blood glucose levels …