Medicine and Health Sciences Commons^™

Unraveling The Impact Of Primary Immunodeficiency Disorders On The Microbiota Of Dental Caries In Children Through 16s Rrna Gene-Based Metagenomic Analysis, Bushra Al-Kebsi̇, Gökhan Kars, Hazal Özer, Şükrü Nai̇l Güner

Turkish Journal of Medical Sciences

Background/aim: Dental caries is a frequently occurring and multifactorial chronic disease in children resulting from the interaction of cariogenic bacteria and host susceptibility. The aim of this study was to elucidate the impacts of primary immunodeficiency disorders (PIDs) on microbiota of dental caries in children by 16S rRNA gene-based metagenomic analysis. Materials and methods: Enrolled in this study were 15 children with primary PID with caries (PID group) and 15 healthy children with caries as a control (CG). The DMFT index, saliva flow rate, and buffering capacity of each participant were assessed before the metagenomic analyses were conducted. For taxonomic …

Clinical Characteristics And Predictors For Recurrence In Chronic Nonbacterial Osteomyelitis: A Retrospective Multicenter Analysis, Kadi̇r Ulu, Rana İşgüder, Şeri̇fe Gül Karadağ, Esra Bağlan, Gülşah Kavrul Kayaalp, Gülçi̇n Otar Yener, Kübra Öztürk, Hafi̇ze Emi̇ne Sönmez, Semanur Özdel, Ferhat Demi̇r, Balahan Makay, Şevket Erbi̇l Ünsal, Betül Sözeri̇, Nuray Aktay Ayaz, Mustafa Çakan

Turkish Journal of Medical Sciences

Background/aim: Chronic nonbacterial osteomyelitis (CNO) is a rare disease of unknown etiology and most commonly occurs during childhood or adolescence. The purpose of this study is to collect data on the clinical features, outcomes, and management of the disease and to identify the factors affecting recurrence. Materials and methods: This is a retrospective multicenter cross-sectional study of pediatric patients diagnosed with CNO. A total of 87 patients with a diagnosis of CNO followed for at least 6 months in 8 pediatric rheumatology centers across the country between January 2010 and December 2021 were included in this study. Results: The study …

Cupressus Arizonica: An Emerging Aeroallergen For East Mediterranean Children, Hi̇lal Ünsal, Ümi̇t Murat Şahi̇ner, Özge Uysal Soyer, Bülent Eni̇s Şekerel

Turkish Journal of Medical Sciences

Background/aim: Cupressus sempervirens is a tree native to the Mediterranean region. We aimed to investigate the frequency of sensitization/allergy to Cupressus arizonica pollen, which is not native to Anatolia. Materials and methods: Patients aged 5?18 years who underwent respiratory allergy screening in Türkiye?s largest referral center over a 1-year period were reviewed retrospectively for a diagnostic study of Cupressus allergy. Results: Of 246 patients, 207 (67.6% male) with a median age of 11.7 (IQR 9.2?15) years were found to be aeroallergen-sensitive and C. arizonica (32%) was the second most common sensitivity after grass pollen (83.6%). In the C. arizonica-sensitive subgroup, …

Reporting The Clinical Spectrum Of Children With Igav In A Retrospective 24-Year Cohort: Influences Of Age And Sex On Clinical Presentation, Sema Yildirim, Müferet Ergüven

Turkish Journal of Medical Sciences

Background/aim: Immunoglobulin A vasculitis (IgAV) is one of the most common types of vasculitis in children. The aims of this study were to investigate the clinical characteristics of the disease, and the effects of age and sex on the clinical course in children with IgAV. Materials and methods: This was a retrospective study including pediatric patients diagnosed with IgAV who attended follow-ups at the pediatric rheumatology department of a tertiary healthcare institution between January 1997 and December 2020. The patients were grouped and compared according to sex and age at diagnosis (<7 years vs. ?7 years). Results: The study included 709 children with IgAV, 392 (55.3%) of whom were male. The mean age at diagnosis was 7.9 ± 3.2 years. The most common disease onset season was autumn (31.2%). Upper respiratory infections (27.8%) were the most common predisposing factors. Gastrointestinal system (GIS), joint, and renal involvement were observed in 52.8%, 47.5%, and 17.5% of patients, respectively. Renal involvement, GIS involvement, and disease relapse were significantly more common among those diagnosed after 7 years of age compared to those diagnosed before the age of 7 (p < 0.001, p = 0.033, and p < 0.001, respectively). Scrotal involvement and subcutaneous edema were more common among those diagnosed at younger than 7 years compared to those aged ?7 years at diagnosis (p < 0.001 and p = 0.016, respectively). GIS involvement was more frequently seen in males compared to females (p = 0.046). Conclusion: It was demonstrated that being ?7 years of age at diagnosis or being a male were associated with higher likelihood of renal and GIS involvement in children with IgAV.

Metabolomic Phenotype Of Hepatic Steatosis And Fibrosis In Mexican Children Living With Obesity, Nayely Garibay-Nieto, Karen Pedraza-Escudero, Isabel Omaña-Guzmán, María José Garcés-Hernández, Eréndira Villanueva-Ortega, Mariana Flores-Torres, José Luis Pérez-Hernández, Mireya León-Hernández, Estibalitz Laresgoiti-Servitje, Juan Carlos Lopez-Alvarenga

School of Medicine Publications and Presentations

Background and Objectives: Metabolic-dysfunction-associated steatotic liver disease or MASLD is the main cause of chronic liver diseases in children, and it is estimated to affect 35% of children living with obesity. This study aimed to identify metabolic phenotypes associated with two advanced stages of MASLD (hepatic steatosis and hepatic steatosis plus fibrosis) in Mexican children with obesity.

Materials and Methods: This is a cross-sectional analysis derived from a randomized clinical trial conducted in children and adolescents with obesity aged 8 to 16 years. Anthropometric and biochemical data were measured, and targeted metabolomic analyses were carried out using mass spectrometry. …

Virtual Education Implementation For Children With Autism Spectrum Disorders Amidst The Covid-19 Pandemic, Monika Sinha-Bhamra

Doctor of Philosophy in Translational Health Sciences Dissertations

Background: The COVID-19 pandemic led to widespread school closures in the Washington DC metropolitan region, necessitating a shift from traditional in-person education to virtual platforms. The context was significantly influenced by the evolving pandemic and its impact on the region's COVID-19 positive rates, with the Washington DC region facing some of the highest positive rates in 2020. These escalating positive rates posed substantial challenges to planning and implementing in-person learning, primarily driven by concerns for public health and safety. The region's persistently low percentages of in-person learning made it one of the worst in the country regarding the provision of …

Vitamin D Deficiency Among Children And Adolescents Living In Sunny South Texas, Yoscelina E. Martinez-Lopez, Margarita Faz, Beatriz Tapia, Juan C. Lopez-Alvarenga, Francisco J. Cervantes

Research Symposium

Background: Exposure to sunlight is essential to produce Vitamin D (ViD). Recent studies suggest obesity is associated with low ViD concentration. Living in South Texas with 220 sunny days a year should be enough to maintain adequate ViD levels. We aimed to analyze ViD levels and obesity in children and adolescents.

Methods: We included 1239 pediatric (1.5 to 18.8 years old) participants (primary care clinic from Laredo) with registered CDC percentiles of BMI (pBMI) and serum concentrations of ViD (Atellica™). Data are described as median (p25, p75), Loess correlation between pBMI and ViD, ANCOVA to adjust by age, sex, and …

The Ventilatory Management Of Paediatric Central Sleep Apnoea: A Systematic Review, Kane A. Hodge, Anne Jones

Internet Journal of Allied Health Sciences and Practice

Purpose: Paediatric central sleep apnoea (CSA) occurs more frequently in the presence of another medical condition. This systematic review aimed to determine the effectiveness of oxygen therapy and non-invasive ventilation (NIV) for children with CSA and additional underlying comorbidities. Method: A search was undertaken of CINAHL Complete, Emcare, Scopus, MEDLINE, and PubMed with forward and backward citations for studies published between database inception and the 5th of May 2022. Articles of any study design or quality were included, excluding systematic reviews, letters, or study protocols. Articles had to involve only paediatric patients with a diagnosis of CSA with …

Sedentary Bout Patterns And Metabolic Health In The Hispanic Community Health Study/Study Of Latino Youth (Sol Youth)., Jordan A. Carlson, Paul R. Hibbing, Bethany Forseth, Keith M. Diaz, Daniela Sotres-Alvarez, Carolina M. Bejarano, Andrea T. Duran, Sheila F. Castañeda, Melawhy L. Garcia, Krista M. Perreira, Martha L. Daviglus, Linda Van Horn, Marc D. Gellman, Carmen R. Isasi, Jianwen Cai, Alan M. Delamater, Vincent S. Staggs, John Thyfault, Linda C. Gallo

Manuscripts, Articles, Book Chapters and Other Papers

Background There is limited evidence on the potential negative metabolic health impacts of prolonged and uninterrupted sedentary bouts in structurally disadvantaged youth. This study investigated associations between sedentary bout variables and metabolic health markers in the Hispanic Community Health Study/SOL Youth (Study of Latino Youth). Methods and Results SOL Youth was a population-based cohort of 1466 youth (age range, 8-16 years; 48.5% female); 957 youth were included in the analytic sample based on complete data. Accelerometers measured moderate-to-vigorous physical activity (MVPA), total sedentary time, and sedentary bout patterns (daily time spent in sedentary bouts ≥30 minutes, median sedentary bout duration, …

What To Expect As Children Transition To Young Adults, Melissa Ponce-Rodas

Lake Union Herald

No abstract provided.

Parental Diabetes Distress Is A Stronger Predictor Of Child Hba1c Than Diabetes Device Use In School-Age Children With Type 1 Diabetes., Susana R. Patton, Nicole Kahhan, Jessica S. Pierce, Matthew Benson, Larry A. Fox, Mark A. Clements

Manuscripts, Articles, Book Chapters and Other Papers

INTRODUCTION: Diabetes distress (DD) describes the unrelenting emotional and behavioral challenges of living with, and caring for someone living with, type 1 diabetes (T1D). We investigated associations between parent-reported and child-reported DD, T1D device use, and child glycated hemoglobin (HbA1c) in 157 families of school-age children.

RESEARCH DESIGN AND METHODS: Parents completed the Parent Problem Areas in Diabetes-Child (PPAID-C) and children completed the Problem Areas in Diabetes-Child (PAID-C) to assess for DD levels. Parents also completed a demographic form where they reported current insulin pump or continuous glucose monitor (CGM) use (ie, user/non-user). We measured child HbA1c using a valid …

Screening Utility And Acceptability Of The Kiswahili-Pgals (Paediatric Gait, Arms, Legs, Spine) At A Tertiary Referral Hospital In Kenya-A Diagnostic Accuracy Study, Jacqueline Kawishe, Anthony Ngugi, Stanley Luchters, Helen Foster, Angela Migowa

Paediatrics and Child Health, East Africa

Background:Paediatric rheumatic diseases cause considerable disease burden to children and their families (Moorthy LN, Peterson MGE, Hassett AL, et al, Pediatric Rheumatology 8:20, 2010). Delayed diagnosis is a signifcant determinant of severity and mortality attributed to these conditions (Foster HE, Eltringham MS, Kay LJ, et al, Arthritis Care Res 57(6):921-7, 2007). pGALS is a simple clinical tool used to assess joints and identify musculoskeletal (MSK) conditions in school-going children to enable early referral to paediatric rheumatologists.

Objectives: This study aimed to translate and determine the diagnostic accuracy and acceptability of a Kiswahili version of the pGALS screening tool among …

Pharmacology Training Of Counselors, Jessica Fanguy Cortez, Chris Rachal

Louisiana Journal of Counseling

As the use of psychotropic medications to treat mental illness increases across the lifespan, the need for psychopharmacology training for counselors intensifies. Research by Sepulveda (2011) concluded that counselor educators are not overwhelmingly supportive of including a psychopharmacology course in CACREP–approved school counselor curricula. Expanding on Sepulveda’s (2011) work, our findings indicate that most CACREP-approved counseling programs do not offer psychological or psychopharmacology courses. Most program directors favor such courses in their programs, and agree that licensed counselors are routinely confronted with medication issues in professional settings. But despite the fact that most programs lack training in psychopharmacology, directors believe …

Educating Counselors-In-Training To Work With Parents Of Minors, Krystal M. Vaughn, Erin M. Dugan, Kellie G. Camelford

Louisiana Journal of Counseling

Counselor education programs offer numerous opportunities for students to receive the necessary knowledge, skills, and experiences to become professional counselors. However, due to limited time, there are areas in the program that are not covered in-depth for various reasons. One such area where students may lack educational or clinical training is in the preparation of working with minors, and more specifically, the treatment of minors surrounding parental consultation practice patterns. The purpose of this article is to define parent consultation, review ethical and legal considerations when working with minors, and to provide counselor educators considerations to utilize when preparing counselors-in-training …

Is The Pediatric Eosinophilic Esophagitis Symptom Score V2.0 Reliable For Telemedicine?, Si̇nem Polat Terece, Di̇lek Yapar, Hacer İlbi̇lge Ertoy Karagöl, Gi̇zem Köken, Demet Teker Düztaş, Ödül Eğri̇taş, Si̇nan Sari, Buket Dalgiç, Arzu Bakirtaş

Turkish Journal of Medical Sciences

Background/aim: Eosinophilic esophagitis (EoE) is a chronic immune-mediated disease. Telemedicine is a healthcare technology used when a patient is separated by distance. The reliability of the Pediatric Eosinophilic Esophagitis Symptom Score, version 2.0 (PEESS v2.0) for telemedicine applications, has not been studied yet. Therefore, we aimed to evaluate the reliability of PEESS v2.0 for telemedicine. Materials and methods: We sent a telesurvey using questionnaires via electronic telecommunication as the telemedicine method. Children with EoE and their parents were asked to complete PEESS v2.0 with the telesurvey method (unsynchronized with the physician) and attend in-person visits one week apart. Intraclass correlation …

Accommodated Gymnastics Program For Atypically Developing Children, Ashtin Callahan

Department of Occupational Therapy Entry-Level Capstone Projects

No abstract provided.

‘Safe Couch, Safe House’ Program (Scshp): Reducing Exposure To Toxic Flame Retardants For Children In A Low-Income Public Housing At Hunters View, Bayview-Hunters Point, San Francisco., Aliza Khan

Master's Projects and Capstones

Since the 1970s, flame retardants have been used extensively in consumer goods, including furniture, textile, and electronics, to meet California’s flammability standards. (Gibson et al.,2019) Polybrominated Diphenyl Ethers (PBDEs), once the most widely used flame retardants being used in consumer products, were phased out from use in manufacturing as evidence emerged about PBDEs persistence and toxicity. (Hoffman et al.,2017) PBDEs were replaced by Organophosphate Flame Retardants (OPFRs), which has proven to be a case of ‘regrettable substitution’ as exposure to OPFRs is ubiquitous and pervasive in humans due to their volatility and propensity to leach from products into the environment. …

Accepting Educational Responsibility For Social Justice: Homeless Mothers’ And Children’S Need Of Education About Health And Nutrition, Smita Guha

Journal of Vincentian Social Action

The goal is to improve health and nutrition among new mothers and their children who were living in shelters. The mothers received workshops and booklets consisting of information, quick and healthy recipes, and learned how to prepare home-made meals with a low budget. The mothers realized nutritious foods are important for them and their children. They learned how to manage time to make nutritious food at the residence. Children regardless of their background, are our future and we need to pay attention to their needs now so that future problems could be prevented. The significance of this study is immense …

The Prevalence Of Diabetes In Juveniles, Tatyana Johnson

Graduate Student Dissertations, Theses, Capstones, and Portfolios

Diabetes mellitus, simply known as diabetes, is a metabolic disorder that impacts how the body makes use of glucose or blood sugar. Glucose is the primary supply of energy for the body’s cells, which is controlled by insulin, a pancreatic hormone. Diabetes results in high blood glucose levels (hyperglycemia), which are caused by either insufficient insulin production by the pancreas or ineffective insulin utilization by the body (Dean & McEntyre, 2004). Although there are several types of diabetes, the two main types are type 1 and type 2. Type 1, also known as juvenile diabetes, is an inflammatory condition in …

Pediatric Streptococcal Pharyngitis Testing And Treatment Practices, Amanda Welch

Dissertations

Objective: The purpose of this pilot quality improvement study was to implement SmartPhrases and assess its impact on adherence to the Infectious Disease Society of America (IDSA) guideline for Group A Streptococcus (GAS) pharyngitis testing and treatment in pediatric patients ages 1-16 years old. The aim was to use SmartPhrases to improve adherence with the IDSA guideline by 30% for GAS pharyngitis swabbing and 10% for appropriate antibiotic prescribing in three months.

Methods: A retrospective data analysis approach was used, in reviewing SmartPhrases data from the electronic health records (EHR) in a metropolitan Urgent Care. This data were collected from …

Incidence And Risk Factors For Chylothorax After Pediatric Heart Surgeries: Retrospective Analysis Of A Large Institution Database​, ​Muhammad Shahzad, Yasser Abdulrhman Alheraish, ​​Bushra ​ Algethami, ​​Patricia ​ Machado, Reem Mohamed Essa Beheri, Gamal Mohamed, Fared Khouqeer, Zohair Al Halees

Journal of the Saudi Heart Association

Background: Risk factors for postoperative chylothorax in children who had cardiothoracic procedures are not always clear. Due to complex course in post-operative care, It’s always challenging to find the risk factors, and their management. Objective: The aim of our study was to identify the incidence, risk factors and effective treatment approaches for chylothorax after pediatric heart surgery. Methods: Children who had the cardiac surgery and subsequently developed chylothorax were included in the study. The ratio of the experimental group to the control group was 1:2. Decannulations of extracorporeal membrane oxygenation (ECMO) were not included in the analysis of patient outcomes. …

Posture Care Management In School Based Settings For Children With Complex Physical Disabilities, Sabrina Rodriguez, Mary Jan Greer, Lee Ann Hoffman

Summer 2023 Virtual OTD Capstone Symposium

Posture care management (PCM) is an intervention that helps protect a person’s body through different positions within different contexts. PCM is not a singular direct intervention as each person is different and has different needs. This process is especially important for those who cannot reposition themselves such as children with complex physical disabilities. These children rely mainly for caregivers and school staff this process since home and school are the main places they spend the beginning years of their lives. Therefore, it is important to educate caregivers and school staff on the guidelines of proper PCM to promote health, well-being, …

The Decline Of Physical Activity With Age In School-Aged Children With Cerebral Palsy: A Single-Center Cross-Sectional Observational Study, Jinuk Lee, Min-Hwa Suk, Soojin Yoo, Jeong-Yi Kwon

Health & Human Performance Faculty Publications and Presentations

Maintaining physical activity is important for children with cerebral palsy (CP). This study examined whether age predicted habitual physical activity (HPA) or cardiorespiratory fitness (CRF) in school-aged children with CP and clarified the relationship between HPA and CRF. We utilized cross-sectional data from 39 children with CP (18 girls and 21 boys; mean age 7.44 years; mean body weight 24.76 kg; mean body mass index 15.97 kg/m2; hemiplegic or diplegic CP). The participants wore an accelerometer (ActiGraph) for five days to measure HPA, physical activity energy expenditure (kcal/kg/d), sedentary physical activity (%SPA), light physical activity, moderate-to-vigorous physical activity (%MVPA), and …

Academic Impacts Of Intergenerational Trauma: Assessing The Relationship Between Ace Scores Of Parents And The Language And Literacy Development Of Their Elementary-Aged Children, Paige Lee Banaszak

Theses and Dissertations

This paper contributes to the current literature by investigating factors that may contribute to language and literacy difficulty among children, to support the future development of effective intervention techniques. The data analyzed in this paper was collected from children and families participating in Reach Every Reader, a research study currently being conducted to improve literacy outcomes in the U.S. by developing a computer-adaptive screening assessment tool to identify children at risk for language and literacy difficulties early in their educational development. Children enrolled in kindergarten through third grade completed tasks that target language and literacy skills, and their parent(s) completed …

Sars-Cov-2 Covid-19 Infection During Pregnancy And Differential Dna Methylation In Human Cord Blood Cells From Term Neonates, Pedro Urday, Suhita Gayen Nee' Betal, Rochelle Sequeira Gomes, Huda B. Al-Kouatly, Kolawole Solarin, Joanna S.Y. Chan, Dongmei Li, Irfan Rahman, Sankar Addya, Rupsa C. Boelig, Zubair H. Aghai

Department of Obstetrics and Gynecology Faculty Papers

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Objective:

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Pediatric Eye Care Treatment Rates And Community Compliance To A Spectacle Provision Program In An Underserved School District In San Diego, Ca, Matthew C.H. Rohn, Flynn O'Sullivan, Stuart I. Brown, Eric Hernandez, Shyamanga Borooah, Iliana Molina

Student Papers, Posters & Projects

SIGNIFICANCE: The need for early identification and treatment of young children's refractive error needs has become a public health concern. The UCSD Eyemobile for Children (EyeMobile) provides vision screenings and comprehensive eye exams on the Eyemobile among a population of underserved, predominantly Hispanic preschool and elementary school children. The program also provides spectacles for children who fail eye exams due to refractive error.

METHODS: We performed a retrospective cross-sectional analysis of all children screened from 2011 to 2017 by the Eyemobile across 10 San Diego elementary schools. We examined demographics, distance and near visual acuity, autorefraction, stereopsis, and color vision. …

Establishing The Minimum Clinically Important Difference (Mcid) Of The Quality Of Life In Childhood Epilepsy Questionnaire (Qolce-55), Mariela Leda

Electronic Thesis and Dissertation Repository

The Quality of Life in Childhood Epilepsy Questionnaire (QOLCE-55) is a validated, parent-reported measure of health-related quality of life (HRQOL) in children with epilepsy (CWE). The QOLCE-55 currently has no minimum clinically important difference (MCID), which is the minimum amount of change required to be considered meaningful to patients. The primary objective of this study was to estimate the MCID for the QOLCE-55 using the Making Mindfulness Matter© in Children with Epilepsy trial data. Parent-child dyads (n=66) completed the QOLCE-55 at baseline (week 0) and follow-up (week 9). MCID values for the QOLCE-55 were calculated using two types of methods: …

Understanding Persistent Bleeding In Children, Bret Lesavoy Dmd, Christine Wang Dds, Richard Yoon Dds

The New York State Dental Journal

This article addresses a rare postoperative complication of persistent bleeding and “liver clot” coagulum following placement of a permanent tooth pre-formed metal crown, an extraction of a carious permanent molar, and an accelerated exfoliating primary molar in an individual with medical compromise, all in young patients. Mild bleeding following dental procedures or tooth exfoliation is not an unusual occurrence; however, persistent bleeding is an uncommon event for patients. A review of literature revealed 15 reports of liver clots following adult dental procedures, but no documented cases of liver clot formation in young patients. The purpose of this article was to …

Recruitment And Reach In A School-Based Pediatric Obesity Intervention Trial In Rural Areas., Bethany Forseth, Brittany Lancaster, Megan Olalde, Christie A. Befort, Rebecca E. Swinburne Romine, Meredith Dreyer, Kelsey Dean, Eve-Lynn Nelson, Ann M. Davis

Manuscripts, Articles, Book Chapters and Other Papers

INTRODUCTION: The purpose of this study is to evaluate two recruitment strategies on schools and participant participation rates and representativeness (reach) within a pediatric obesity treatment trial tailored for families who live in rural areas.

METHODS: Recruitment of schools was evaluated based on their progress toward enrolling participants. Recruitment and reach of participants were evaluated using (1) participation rates and (2) representativeness of demographics and weight status of participants compared to eligible participants (who did not consent and enroll) and all students (regardless of eligibility). School recruitment, as well as participant recruitment and reach, were evaluated across recruitment methods comparing …

Audiological Management Of Children With Down Syndrome: A Toolkit For Caregivers, Natalie Lisiewicz

Dissertations, Theses, and Capstone Projects

Children with Down syndrome may have multiple medical co-morbidities. This can result in an overwhelming number of medical appointments and information for caregivers to keep track of. Middle ear dysfunction, among other otologic abnormalities, is common in the Down syndrome population, and the presence of these conditions will result in referrals to an audiologist to monitor hearing sensitivity. While hearing may not be the most pressing concern as compared to a possible life-threatening condition such as a heart defect, it is still a crucial factor in a child’s overall development.

This toolkit is designed with the intention of educating caregivers …