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Full-Text Articles in Medicine and Health Sciences
Controlling Viral Immuno-Inflammatory Lesions By Modulating Aryl Hydrocarbon Receptor Signaling, Tamara Veiga-Parga, A Suryawanshi, B T. Rouse
Controlling Viral Immuno-Inflammatory Lesions By Modulating Aryl Hydrocarbon Receptor Signaling, Tamara Veiga-Parga, A Suryawanshi, B T. Rouse
Tamara Veiga-Parga
Ocular herpes simplex virus infection can cause a blinding CD4+ T cell orchestrated immuno-inflammatory lesion in the cornea called Stromal Keratitis (SK). A key to controlling the severity of SK lesions is to suppress the activity of T cells that orchestrate lesions and enhance the representation of regulatory cells that inhibit effector cell function. In this report we show that a single administration of TCDD (2, 3, 7, 8- Tetrachlorodibenzo-p-dioxin), a non-physiological ligand for the AhR receptor, was an effective means of reducing the severity of SK lesions. It acted by causing apoptosis of Foxp3- CD4+ T cells but had …
Short Term Effects Of Genistein On The Testes Of Quail (Coturnix Coturnix), Meli̇ke Belkiz Erkan, Serap Eki̇nci̇
Short Term Effects Of Genistein On The Testes Of Quail (Coturnix Coturnix), Meli̇ke Belkiz Erkan, Serap Eki̇nci̇
Turkish Journal of Veterinary & Animal Sciences
Although there have been a number of studies on the effects of phytoestrogens, especially genistein, on testes, its effects on the testis tissue of birds have not been studied yet. The present study aims to reveal the effects of genistein on quail testes through the use of histological and immunohistochemical methods. In the study, a total of 64 male quails (Coturnix coturnix) were used, each of which was 50 days old. Three different doses of genistein were administered by gavage to the separate groups at intervals of 15 and 30 days. According to the results of the histological analysis and …
Mammary Cell Activity And Turnover In Dairy Cows Treated With The Prolactin-Release Inhibitor Quinagolide And Milked Once Daily, M. Boutinaud, V. Lollivier, L. Finot, R. M. Bruckmaier, P. Lacasse
Mammary Cell Activity And Turnover In Dairy Cows Treated With The Prolactin-Release Inhibitor Quinagolide And Milked Once Daily, M. Boutinaud, V. Lollivier, L. Finot, R. M. Bruckmaier, P. Lacasse
Physiology Collection
To assess the regulation of mammary cell activity, survival, and proliferation by prolactin (PRL), 5 Holstein cows in early lactation received daily i.m. injections of 1 mg of quinagolide, a suppressor of PRL release, for 9 wk, whereas 4 control cows received the vehicle (water) only. During the last week of treatment, one udder half was milked once a day (1×) and the other twice a day (2×). Mammary biopsies were harvested 1 wk before and 4 and 8 wk after the start of quinagolide treatment. The quinagolide injections reduced milk yield and resulted in lower levels of κ-casein and …