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Full-Text Articles in Medicine and Health Sciences
Haemophilus Influenzae In Adults: An Analysis Of Incidence, Serotype, Biotype, Beta-Lactamase Production And Clinical Spectrum, Mildred Ramsey Norris
Haemophilus Influenzae In Adults: An Analysis Of Incidence, Serotype, Biotype, Beta-Lactamase Production And Clinical Spectrum, Mildred Ramsey Norris
MSN Research Projects
A selective medium, chocolate agar with vancomycin, bacitracin, and clindamycin, was used to enhance the recovery of Haemophilus influenzae from adult patients. Cultures of the 634 respiratory specimens yielded 130 (20.5 percent) H. influenzae isolates, representing 93 patients. The serotype, biotype, and Beta-lactamase production of all isolates were determined. Of 103 distinct isolates, nine percent were serotypable and included serogroups a ,b ,d ,and e. Although biotypes I, II, III, V, and VI were represented, 81.5 percent of the isolates were in the II/III group. Twenty-six percent of the isolates were Beta-lactamase producers and, therefore, ampicillin resistant. The clinical characteristics …
Heterogeneity Of Clonogenic Cells In Acute Myeloblastic Leukemia., Kert D. Sabbath, Edward D. Ball, Peter Larcom, Roger B. Davis, James D. Griffin
Heterogeneity Of Clonogenic Cells In Acute Myeloblastic Leukemia., Kert D. Sabbath, Edward D. Ball, Peter Larcom, Roger B. Davis, James D. Griffin
Dartmouth Scholarship
The expression of differentiation-associated surface antigens by the clonogenic leukemic cells from 20 patients with acute myeloblastic leukemia (AML) was studied with a panel of seven cytotoxic monoclonal antibodies (anti-Ia, -MY9, -PM-81, -AML-2-23, -Mol, -Mo2, and -MY3). The surface antigen phenotypes of the clonogenic cells were compared with the phenotypes of the whole leukemic cell population, and with the phenotypes of normal hematopoietic progenitor cells. In each case the clonogenic leukemic cells were found within a distinct subpopulation that was less "differentiated" than the total cell population. Clonogenic leukemic cells from different patients could be divided into three phenotype groups. …