Medicine and Health Sciences Commons^™

Genetic Counselling And Testing For Inherited Gene Mutations In Newly Diagnosed Patients With Breast Cancer: A Review Of The Existing Literature And A Proposed Research Agenda, Bettina Meiser, Kathy Tucker, Michael Friedlander, Kristine Barlow-Stewart, Elizabeth Lobb, Christobel Saunders, Gillian Mitchell

Research outputs pre 2011

Many women newly diagnosed with breast cancer and with a strong family history of breast cancer are referred to a family cancer service for genetic counselling and for consideration of genetic testing for germline mutations in cancer predisposition genes following completion of their cancer treatment. However, there is growing evidence that mutation status may influence treatment recommendations, and that there may be benefits in having 'treatment-focused genetic counselling and testing' available shortly after cancer diagnosis. This article reviews the literature that could inform the development of treatment-focused genetic counselling and testing, including: the rationale for genetic testing to aid with …

A Luteinizing Hormone Receptor Intronic Variant Is Significantly Associated With Decreased Risk Of Alzheimer's Disease In Males Carrying An Apolipoprotein E Epsilon 4 Allele, Ryan J. Haasl, M Reza Ahmadi, Sivan Vadakkadath Meethal, Carey E. Gleason, Sterling C. Johnson, Sanjay Asthana, Richard L. Bowen, Craig S. Atwood

Research outputs pre 2011

Genetic and biochemical studies support the apolipoprotein E (APOE) ε4 allele as a major risk factor for late-onset Alzheimer's disease (AD), though ~50% of AD patients do not carry the allele. APOE transports cholesterol for luteinizing hormone (LH)-regulated steroidogenesis, and both LH and neurosteroids have been implicated in the etiology of AD. Since polymorphisms of LH beta-subunit (LHB) and its receptor (LHCGR) have not been tested for their association with AD, we scored AD and age-matched control samples for APOE genotype and 14 polymorphisms of LHB and LHCGR. Thirteen gene-gene interactions between the …

Developing The Anker Bilateral Spatial System, Janet Richmond

ECU Posters

Determining the effect of using the Anker Bilateral Spatial System (ABSS) to enhance the development of bilateral and spatial functioning of individuals with visual perceptual or sensory processing difficulties.

The Development Of A Test Of Letter And Number Reversal Tendency For Primary School Children, Janet Richmond, Ted Brown

ECU Posters

Development of a standardised instrument to assess visual perceptual skills or primary age school children using letters and numbers

The Potential Role Of Life-Writing Therapy In Facilitating 'Recovery' For Those With Mental Illness, Philip Max Neilsen, Ffion Murphy

Research outputs pre 2011

This article addresses the experience of designing and conducting life-writing workshops for a group of clients with severe mental illness; the aim of this pilot study was to begin to determine whether such writing about the self can aid in individual ‘recovery’, as that term is understood by contemporary health professionals. A considerable amount has been written about the potential of creative writing in mental health therapy; the authors of this article provide a brief summary of that literature, then of the concept of ‘recovery’ in a psychology and arts therapy context. There follows a first-hand account by one of …

Regional Differences In Lumbar Spinal Posture And The Influence Of Low Back Pain, Tim Mitchell, Peter O'Sullivan, Angus Burnett, Leon Straker, Anne Smith

Research outputs pre 2011

Background: Spinal posture is commonly a focus in the assessment and clinical management of low back pain (LBP) patients. However, the link between spinal posture and LBP is not fully understood. Recent evidence suggests that considering regional, rather than total lumbar spine posture is important. The purpose of this study was to determine; if there are regional differences in habitual lumbar spine posture and movement, and if these findings are influenced by LBP. Methods: One hundred and seventy female undergraduate nursing students, with and without LBP, participated in this cross-sectional study. Lower lumbar (LLx), Upper lumbar (ULx) and total lumbar …

The Lived Experience Of Self-Intermittent Catheterisation In People With Spinal Cord Injury, Brendan J. Bakes

Theses: Doctorates and Masters

Self-intermittent catheterisation (SIMC) is one of the most common and safest methods of bladder emptying in people with spinal cord injury (SCI). There is a large amount of literature relating to the biomedical aspects of SIMC, such as infection rates and renal complications. There is however, very little information about how people actually experience SIMC and its effect on their daily lives. Through a series of semi-structured interviews this study describes the lived experience of eight men with spinal cord injuries who perform self-intermittent catheterisation to empty their bladder. The study uses Husserlian phenomenology and Colaizzi's method to analyse data …

Promoting Healthy Weight In The Preschool Years: A Portfolio And Planning Guide To Address Barriers In Primary Care, Margaret Miller, Renee Campbell-Pope, Lydia Hearn

Research outputs pre 2011

The rapidly rising incidence of overweight and obesity in Australia, particularly among young children has led to an urgent need for effective prevention. Recent figures indicate that 15% of preschool children in Australia are overweight, and a further 6% are obese1,2, with rates rising steadily especially among children from lower socioeconomic groups.

Family, childcare, primary health care, early childhood education and the community are influential environments for young children3-7 with the potential to engage in an integrated approach to promote healthy weight and development of healthy eating and active lifestyle habits during the pre-school years5,8,9.

In 2006, the Child Health …

Falls, Depression And Antidepressants In Later Life: A Large Primary Care Appraisal, Ngaire Kerse, Leon Flicker, Jon J. Pfaff, Brian Draper, Nicola T. Lautenschlager, Moira Sim, John Snowdon, Osvaldo P Almeida

Research outputs pre 2011

Background: Depression and falls are common and co-exist for older people. Safe management of each of these conditions is important to quality of life.

Methods: A cross-sectional survey was used to examine medication use associated with injurious and non-injurious falls in 21,900 community-dwelling adults, aged 60 years or over from 383 Australian general practices recruited for the DEPS-GP Project. Falls and injury from falls, medication use, depressive symptoms (Primary Health Questionnaire (PHQ-9)), clinical morbidity, suicidal ideation and intent, health status (SF-12 Health Survey), demographic and lifestyle information was reported in a standardised survey.

Findings: Respondents were 71.8 years (sd 7.7) …

Participation In Sports, Arts And Racing And Its Relationship To Message Literacy And Health Behaviours, Christina Mills, Michael Rosenberg, Sarah French, Jenna Mitchell, Lisa Wood

Research outputs pre 2011

The purpose of this study was to assess health message awareness and health behaviours by participation/non participation in sport, arts and racing (SAR) in Western Australia. In this study a 'participant' was defined as someone who was (1) a member of a SAR organisation, group or club; and/or (2) having attended a SAR event as a spectator or audience member in the last 12 months. A 'non participant' was someone who did not participate in any SAR events as a member and/or spectator and/or audience member in the last 12 months.

Research Criteria For The Diagnosis Of Alzheimer's Disease: Genetic Risk Factors, Blood Biomarkers And Olfactory Dysfunction, Jonathan Foster, Hamid Sohrabi, Giuseppe Verdile, Ralph Martins

Research outputs pre 2011

No abstract provided.

Review Of The Social And Emotional Wellbeing Of Indigenous Australian Peoples, Darren Garvey

Research outputs pre 2011

The first case of diabetes among Indigenous people was recorded in Adelaide in 1923. Records prior to this time showed that Indigenous people were fit, lean, and did not suffer from any form of metabolic condition, which were largely believed to be a characteristic of European populations. The earliest detailed studies investigating the development of diabetes in Indigenous populations were not undertaken, however, until the early 1960s. These and subsequent studies found a significant correlation between the development of a ‘westernised’ lifestyle and the levels of type 2 diabetes in the Indigenous population.

Since that time, type 2 diabetes has …

A Review Of The Evaluation Of Healthway Sponsorships, Michael Rosenberg, Christina Mills, Joanna Granich, Renee Ferguson, Sarah French, Lisa Wood

Research outputs pre 2011

This study reviewed the methods used by Healthway to assess sponsorship implementation/value and to explore complimentary or alternative evaluation measures...

Interview questions related to sponsorship activities, procedures, requirements and evaluation. Suggestions for practical and alternative ways of assessing sponsorship implementation and conducting evaluations were also asked. In addition, the perceived value of sponsorship investments to Healthway and satisfaction with the existing evaluation framework were also sought...

The Relationship Between Isometric And Dynamic Strength In College Football Players, Michael R. Mcguigan, Jason Winchester

Research outputs pre 2011

Previous research has demonstrated the importance of both dynamic and isometric maximal strength and rate of force development (RFD) in athletic populations. The purpose of this study was to examine the relationships between measures of isometric force (PF), RFD, jump performance and strength in collegiate football athletes. The subjects in this study were twenty-two men [(mean ± SD):age 18.4 ± 0.7 years; height 1.88 ± 0.07 m; mass 107.6 ± 22.9 kg] who were Division I college football players. They were tested for PF using the isometric mid thigh pull exercise. Explosive strength was measured as RFD from the isometric …

Association Of Alleles Carried At Tnfa -850 And Bat1 -22 With Alzheimer's Disease, Anastazija Gnjec, Katarzyna D'Costa, Simon Laws, Ross Hedley, Kelvin Balakrishnan, Kevin Taddei, Georgia Martins, Athena Paton, Giuseppe Verdile, Samuel Gandy, Anthony Broe, William Brooks, Hayley Bennett, Olivier Piguet, Patricia Price, Judith Miklossy, Joachim Hallmayer, Patrick Mcgeer, Ralph Martins

Research outputs pre 2011

Background: Inflammatory changes are a prominent feature of brains affected by Alzheimer's disease (AD). Activated glial cells release inflammatory cytokines which modulate the neurodegenerative process. These cytokines are encoded by genes representing several interleukins and TNFA, which are associated with AD. The gene coding for HLA-B associated transcript 1 (BAT1) lies adjacent to TNFA in the central major histocompatibility complex (MHC). BAT1, a member of the DEAD-box family of RNA helicases, appears to regulate the production of inflammatory cytokines associated with AD pathology. In the current study TNFA and BAT1 promoter polymorphisms were analysed in AD and control cases and …

Organisational Survey: Impact Of Healthway Funding On Currently Funded And Previously Funded Sar Organisations, Michael Rosenberg, Sarah French, Jenna Mitchell, Christina Mills, Lisa Wood

Research outputs pre 2011

Since 1992, organisations in receipt of Healthway funding have demonstrated consistently high levels of commitment to sponsorship requirements. In part, the high levels of commitment observed may reflect a trend towards organisations with similar values to Healthway applying for funding. Organisations with different values to Healthway may receive funding once and decide that the sponsorship does riot match the needs of their organisation. This may result in difficulties fo.r Healthway to access hard to reach organisations, or to establish longer-term partnerships with Sports, Arts or Racing (SAR) organisations that target high priority groups. To better understand how Healthway's requirements of …

Pax7 Is Requisite For Maintenance Of A Subpopulation Of Superior Collicular Neurons And Shows A Diverging Expression Pattern To Pax3 During Superioir Collicular Development, Jennifer Thompson, Andreas Zembrzycki, Ahmed Mansouri, Melanie Ziman

Research outputs pre 2011

Pax7 encodes a transcription factor well-established as an important determinant of mesencephalic identity and superior collicular development. Pax7 mutant mice, however, present with no obvious morphological impairments to the superior colliculus. This finding is paradoxical and has been attributed to functional redundancy afforded by its paralogue Pax3. Here we utilise Pax7 mutant mice to investigate the precise role of this important developmental regulator during superior collicular development and neuronal specification/differentiation. We also assess its spatiotemporal relationship with Pax3 during embryonic development. Analysis of the superior colliculus of Pax7 mutant and wildtype mice at a variety of developmental timepoints revealed that …

Knowledge And Perceptions About Hepatitis C Among Police Undertaking Training At The Western Australia Police Academy, Cerissa Papanastasiou

Theses : Honours

Hepatitis C (HCV) is a significant health issue in Australia with approximately 90% of new cases attributed to injecting drug use (IDU). With no vaccination for this infection it is important that preventive methods are utilised to reduce the likelihood of it being transmitted from the IDU community into the wider community. Research has suggested that people's beliefs, which are influenced by the knowledge they have, play an important role in influencing the action people take in protecting and promoting their health. While there are numerous studies which have measured the HCV-related knowledge and perceptions of other professions in the …

The Leadership Characteristics Registered Nurses Perceive As Important In Their Clinical Nurses, Linda May Aitken

Theses : Honours

Limited research exists about the leadership attributes registered nurses (RNs) want from their clinical nurses (CNs). This study explored the leadership attributes Western Australian RNs considered important in CNs and determine if there were differences in the choice of preferred CN attributes according to RNs years of experience; types of nursing education; level of seniority and nursing specialty. A modified version of the Emerging Workforce's Preference Survey was distributed to 403 RNs with a 30% response rate. The respondents ranked their top three preferences from 4 clusters of traits. S.P.S.S. 15.0 was used to summarise demographic data and then analyse …

Is Enough Really Enough? : Evaluation Of An Alcohol Awareness Campaign At Ecu Joondalup, Marissa Macdonald

Theses : Honours

Australian young adults aged 17-25 years old attending university are more likely to drink at levels which put themselves at risk of both short and long term alcohol-related harm. University settings are an appropriate place to target university students with alcohol education or awareness-raising campaigns. Australian research on this topic is relatively limited. This mixed methods study involved two phases. The first phase quantitatively evaluated the impact of the 'Enough is Enough' campaign, implemented by the North Metropolitan Community Drug Service Team at ECU Joondalup, on students' awareness of the consequences of excessive alcohol use and perceived acceptability of drunkenness. …

Evaluation Of A Community Radio Station In Tulikup, Bali: Indonesia, Dane Anthony Waters

Theses : Honours

Community-oriented radio can be a valuable tool to mobilise communities and contribute to making positive social changes throughout the world (Dagron, 2001). Heartline Bali FM is a community-oriented radio station, which since development, has sought to positively impact the people within the community it serves. Located in the rural Balinese village of Tulikup, Indonesia, the station has responded practically to the health and social needs of the community through radio and other social development strategies since its establishment in 2003. In 2004, a base-line needs assessment was conducted within the village to help inform the radio station of the health …

The Benefits Of Pet Ownership For Single Adults In Midlife, Lauren Mcgillivray

Theses : Honours

Pets are shown to enhance quality of life through support and companionship. Midlife is a time where pets may be most valuable, since it is a time that involves critical changes to intimate relationships, roles and status. In this article a critical review of the literature on midlife development and demographic trends was carried out. Further, the psychological literature on human-pet relationships was reviewed and integrated with midlife research. Evidence for the psychological and physical benefits of pets is examined and the implications and potential benefits for middle aged adults are discussed. Findings suggest that pets may help to reduce …

Gender And Apologies: Exploring Offended Females' Perceptions Of Apologies From Males And Females, Stacey Bennet

Theses : Honours

The construct of apology has recently received more attention by researchers (Allan, 2007) and several factors that may influence apologetic responses have been identified. The gender of an offender is one such factor. A review was undertaken to examine the literature pertaining to the influence of the gender of an offender on apologies. As a result of the review, several themes were identified. These included gender differences and similarities in the frequency of apologies, the quantity and complexity of components, and the actual content of those components. Furthermore, contextual factors that may play a role in the influence of gender …

The Evaluation Of Midazolam On Head Injured Patients In The Prehospital Setting, Dragana Klinac

Theses: Doctorates and Masters

Midazolam (Hypnovel ®) is the only sedating agent used by paramedics at St John Ambulance Service W.A. in the management of many conditions including seizure activities, antisocial or uncontrollable behaviours, back pain incidents and head injuries. Midazolam, with a rapid absorption, fast onset of action and short duration on neurological activity, has been accepted as a safe and effective agent in prehospital treatment since the late-1990s. Often, if a patient is not complying with treatment or is uncontrollable or aggressive, paramedics are required to sedate the individual. This study primarily examines the use of midazolam for the sedation of unmanageable …

The Effect Of Nurse Initiated Paracetamol On Emergency Department Patients With Pain From Low Acuity Injury, Joanne G. Wilson

Theses: Doctorates and Masters

Early identification and management of pain was identified at the commencement of this study as a key area requiring research in emergency departments. Prolonged waiting times for analgesia especially, was highlighted in the National Institute of Clinical Studies emergency department collaborative in 2003. Many barriers exist for a patient to receive analgesia. In Western Australia this is compounded by the legislation which restricts prescribing rights for nurses. Three considerations guided the development of the research project. Firstly, the patient has initial contact with the emergency department from the nurse at triage. Secondly, paracetamol was recognised as a potentially effective analgesic …

Exploring The Pap Smear Experiences Of Women Aged 18 To 25 : Moving From Intention To Action, Gemma Malatesta

Theses : Honours

The aim of this research was to explore the Pap smear experiences of young women aged 18 to 25. The effectiveness of Pap smear screening and the barriers to obtaining one have been well researched. However, there is limited information in the literature on young women's experiences of Pap smear screening and the context in which they move from intending to be screened to actually undertaking the screening. This qualitative study, underpinned by a constructivist paradigm informed by a feminist epistemology, consisted of eight semi structured interviews with young women who had participated in Pap smear screening. Data analysis using …

A Study Of Compliance In Aged Care Facilities With Regards To Australian Standards 1851:2006 Maintenance Of Fire Protection Systems And Equipment Section 17, Robert Doleman

Theses : Honours

The management of risk within a nursing home environment is widely viewed as an undertaking perfom1ed by the owners or managers of nursing homes. The residents of these homes are reliant upon the owners and managers to keep them safe, due in part to a traditional belief that they are the experts and have a greater understanding of risk. To establish risk it is first a requirement to have an understanding of levels of risk and risk management techniques. Risk appreciation is often influenced by heuristic representativeness, as well as social and cultural influences. The higher level of risk within …

The Relationship Between Nicotine Dependence And Symptoms Of Anxiety, Depression And Stress In A Therapeutic Community For Alcohol And Other Drug Rehabilitation, Thomas Hopkins

Theses : Honours

Smoking tobacco is the largest single risk factor for premature death in developed countries. It is also associated with the greatest economic cost of all drugs in Australian society. In addition to the health and economic consequences associated with smoking, it has also been associated with mental health problems. Smoking has been associated with anxiety, depression and stress, as well as more pervasive disorders such as panic disorder and agoraphobia. It is not clear whether smoking contributes to mental health problems or individuals with mental health problems smoke to alleviate symptoms. It may be there are genetic factors that contribute …

Determining Standard Criteria For Endotracheal Suctioning In The Paediatric Intensive Care Patient: An Exploratory Study [Thesis], Kylie Davies

Theses: Doctorates and Masters

Endotracheal tube (ETT) suction is a common nursing procedure within the paediatric intensive care (PIC) setting. Significant side effects associated with this procedure can dramatically affect the stability of the critically ill ventilated paediatric patient. A comprehensive literature review failed to establish clear standards for determining when the procedure is warranted, especially in the paediatric population. This can present difficulty for the inexperienced paediatric intensive care nurse when assessing a patient's need for ETT suction. The aim of the research was to design an evidence based endotracheal suction assessment tool (ESAT) for use by nurses caring for paediatric patients. The …

Does Training With Powercranks™ Affect Economy Of Motion, Cycling Efficiency, Oxygen Uptake And Muscle Activation Patterns In Trained Cyclists?, Jack Burns

Theses: Doctorates and Masters

PowerCranks™ are claimed to increase economy of motion and cycling efficiency by reducing the muscular recruitment patterns that contribute to the resistive forces occurring during the recovery phase of the pedal stroke. However, scientific research examining the efficacy of training with PowerCranks™ is lacking. Therefore, the purpose of this study was to determine if five weeks of training with PowerCranks™ improves economy of motion (EOM), gross efficiency (GE), oxygen uptake (V.O2) and muscle activation patterns in trained cyclists. Sixteen trained cyclists were matched and paired into either a PowerCranks™ (PC) or Normal Cranks (NC) training group. Prior to training, all …