Medicine and Health Sciences Commons^™

Stressful Life Events As Predictors Of Functioning: Findings From The Collaborative Longitudinal Personality Disorders Study, Maria E. Pagano, Andrew E. Skodol, Robert L. Stout, M. Tracie Shea, Shirley Yen, Carlos M. Grilo, Charles A. Sanislow, Donna S. Bender, Thomas H. Mcglashan, Mary C. Zanarini, John G. Gunderson

Charles A. Sanislow, Ph.D.

Objective:  Although much attention has been given to the effects of adverse childhood experiences on the development of personality disorders (PDs), we know far less about how recent life events influence the ongoing course of functioning. We examined the extent to which PD subjects differ in rates of life events and the extent to which life events impact psychosocial functioning. Method:  A total of 633 subjects were drawn from the Collaborative Longitudinal Personality Disorders Study (CLPS), a multi-site study of four personality disorders – schizotypal (STPD), borderline (BPD), avoidant (AVPD), obsessive-compulsive (OCPD) – and a comparison group of major depressive …

Associations In The Course Of Personality Disorders And Axis I Disorders Over Time, M. Tracie Shea, Robert L. Stout, Shirley Yen, Maria E. Pagano, Andrew E. Skodol, Leslie C. Morey, John G. Gunderson, Thomas H. Mcglashan, Carlos M. Grilo, Charles A. Sanislow, Donna S. Bender, Mary C. Zanarini

Charles A. Sanislow, Ph.D.

In this study, the authors examined time-varying associations between schizotypal (STPD), borderline (BPD), avoidant (AVPD), or obsessive-compulsive (OCPD) personality disorders and co-occurring Axis I disorders in 544 adult participants from the Collaborative Longitudinal Personality Disorders Study. The authors tested predictions of specific longitudinal associations derived from a model of crosscutting psychobiological dimensions (L. J. Siever & K. L. Davis, 1991) with participants with the relevant Axis I disorders. The authors assessed participants at baseline and at 6-, 12-, and 24-month follow-up evaluations. BPD showed significant longitudinal associations with major depressive disorder and posttraumatic stress disorder. AVPD was significantly associated with …

Two-Year Stability And Change Of Schizotypal, Borderline, Avoidant And Obsessive-Compulsive Personality Disorders, Carlos M. Grilo, M. Tracie Shea, Charles A. Sanislow, Andrew E. Skodol, John G. Gunderson, Robert L. Stout, Maria E. Pagano, Shirley Yen, Leslie C. Morey, Mary C. Zanarini, Thomas H. Mcglashan

Charles A. Sanislow, Ph.D.

he authors examined the stability of schizotypal (STPD), borderline (BPD), avoidant (AVPD) and obsessive-compulsive (OCPD) personality disorders (PDs) over 2 years of prospective multiwave follow-up. Six hundred thirty-three participants recruited at 4 collaborating sites who met criteria for 1 or more of the 4 PDs or for major depressive disorder (MOD) without PD were assessed with semistructured interviews at baseline, 6, 12, and 24 months. Lifetable survival analyses revealed that the PD groups had slower time to remission than the MDD group. Categorically, PD remission rates range from 50% (AVPD) to 61% (STPD) for dropping below diagnostic threshold on a …

Temporal Coherence Of Criteria For Four Personality Disorders, Leslie C. Morey, Andrew E. Skodol, Carlos M. Grilo, Charles A. Sanislow, Mary C. Zanarini, M. Tracie Shea, John G. Gunderson, Thomas H. Mcglashan

Charles A. Sanislow, Ph.D.

This study sought to investigate the coherence of changes observed in diagnostic criteria for borderline, schizotypal, obsessive-compulsive, and avoidant personality disorders. Five hundred, forty-nine patients were independently evaluated 2 years apart, and correlations of observed changes in each diagnostic criterion with changes in other criteria were examined to determine if there was within-syndrome consistency in these changes. The observed changes in criteria were consistent within syndrome (median alpha = 0.72 across 4 disorders), and reasonably specific to that syndrome relative to the other disorders. The results support the validity of these criterion sets as representing coherent syndromes.

Longitudinal Diagnostic Efficiency Of Dsm-Iv Criteria For Obsessive–Compulsive Personality Disorder: A 2-Year Prospective Study, Carlos M. Grilo, Andrew E. Skodol, John G. Gunderson, Charles A. Sanislow, Robert L. Stout, M. Tracie Shea, Leslie C. Morey, Mary C. Zanarini, Donna S. Bender, Shirley Yen, Thomas H. Mcglashan

Charles A. Sanislow, Ph.D.

Objective: To examine the longitudinal diagnostic efficiency of the DSM-IV criteria for obsessive–compulsive personality disorder (OCPD).

Method: At baseline, criteria and diagnoses were determined using diagnostic interviews, and blinded assessments were performed 24 months later with 550 participants. Diagnostic efficiency indices (conditional probabilities, total predictive power, and kappa) were calculated for each criterion determined at baseline, using the independent OCPD diagnosis at follow-up as the standard.

Results: Longitudinal diagnostic efficiencies for the OCPD criteria varied; findings suggested the overall predictive utility of preoccupied with details, rigid and stubborn, and reluctant to delegate.

Conclusion: These findings suggest the predictive validity of …

The Longitudinal Relationship Of Personality Traits And Disorders, Megan B. Warner, Leslie C. Morey, John F. Finch, John G. Gunderson, Andrew E. Skodol, Charles A. Sanislow, M. Tracie Shea, Thomas H. Mcglashan, Carlos M. Grilo

Charles A. Sanislow, Ph.D.

Personality disorders are presumed to be stable because of underlying stable and maladaptive personality traits, but while previous research has demonstrated a link between personality traits and personality disorders cross-sectionally, personality disorders and personality traits have not been linked longitudinally. This study explores the extent to which relevant personality traits are stable in individuals diagnosed with 4 personality disorders (schizotypal, borderline, avoidant, and obsessive-compulsive personality disorders) and examines the assumption that these personality disorders are stable by virtue of stable personality traits. This assumption was tested via the estimation of a series of latent longitudinal models that evaluated whether changes …

Childhood Maltreatment Associated With Adult Personality Disorders: Findings From The Collaborative Longitudinal Personality Disorders Study, Cynthia L. Battle, M. Tracie Shea, Dawn M. Johnson, Caron Zlotnick, Mary C. Zanarini, Charles A. Sanislow, Andrew E. Skodol, John G. Gunderson, Carlos M. Grilo, Thomas H. Mcglashan, Leslie C. Morey

Charles A. Sanislow, Ph.D.

No abstract provided.