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1999

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Full-Text Articles in Medicine and Health Sciences

Behçet's Disease-A Literature Review(โรคบีเชตส์), Poramate Pitak-Arnnop Sep 1999

Behçet's Disease-A Literature Review(โรคบีเชตส์), Poramate Pitak-Arnnop

Chulalongkorn University Dental Journal

Behçet's disease is a multisystemic inflammatory disease with histological evidence for vasculitis and characterized by mucocutaneous, ocular, articular, vascular, intestinal, pulmonary, renal and neurologic involvement. According to the diagnostic criteria formed by the International Study Group, recurrent oral ulceration is a prerequisite, with two more typical symptoms or signs. It is a disease of young adults with a more severe course in male subjects. Its prevalence is high in the Mediterranean basin, Turkey, Japan and those ethnic groups along the old Silk Route and has been known to be associated with HLA-B5 and HLA-B11. Although the pathogenesis of the disease …


Polynucleotides Related To Monoclonal Antibody 1a7 And Use For The Treatment Of Melanoma And Small Cell Carcinoma, Malaya Chatterjee, Kenneth A. Foon, Sunil K. Chatterjee Aug 1999

Polynucleotides Related To Monoclonal Antibody 1a7 And Use For The Treatment Of Melanoma And Small Cell Carcinoma, Malaya Chatterjee, Kenneth A. Foon, Sunil K. Chatterjee

Microbiology, Immunology and Molecular Genetics Faculty Patents

The present invention relates to monoclonal antibody 1A7. This is an anti-idiotype produced by immunizing with an antibody specific for ganglioside GD2, and identifying a hybridoma secreting antibody with immunogenic potential in a multi-step screening process. Also disclosed are polynucleotide and polypeptide derivatives based on 1A7, including single chain variable region molecules and fusion proteins, and various pharmaceutical compositions. When administered to an individual, the 1A7 antibody overcomes immune tolerance and induces an immune response against GD2, which comprises a combination of anti-GD2 antibody and GD2-specific T cells. The invention further provides methods for treating a disease associated with altered …


Identification Of Needs In Treatment Of Breast Cancer, Luann Massey Aug 1999

Identification Of Needs In Treatment Of Breast Cancer, Luann Massey

MSN Research Projects

Breast cancer has been documented as the second leading cause of death in American women. Many needs are realized during the phases of treatment for breast cancer: at the time of diagnosis, during treatment, and after treatment. The purpose of this descriptive exploratory study was to identify the needs of women with breast cancer during phases of treatment. With the Neuman Systems Model as a theoretical framework, the research question was as follows : What are the needs of women with breast cancer during the phases of treatment? Data were obtained using the Massey Subject Profile and the Massey Questionnaire. …


Methods Of Treating Eye Conditions With Human Leukocyte Elastase (Hle) Inhibitory Agents, George A. Digenis, Charles Khouri Jul 1999

Methods Of Treating Eye Conditions With Human Leukocyte Elastase (Hle) Inhibitory Agents, George A. Digenis, Charles Khouri

Pharmaceutical Sciences Faculty Patents

A method of reducing corneal scarring or fibroblast proliferation comprises applying to an area of a subject's eye afflicted with the condition a corneal scar-fibroblast proliferation-reducing amount of a free or polymer-bound HLE inhibitory agent under conditions and for a period of time effective to attain the desired effect. A method of reducing neovascularization of corneal scar tissue comprises applying to an area of a subject's eye afflicted with the condition a neovascularization-inhibitory amount of a free or polymer-bound HLE inhibitory agent under conditions and for a period of time effective to attain the desired effect.


Screening Of Hepatitis C Virus Antibody In Hiv - Riskgroup: Comparison Between Hiv - Infectedsubjects And Hiv - Uninfected Subjects, P. Luksamijarukul, S. Tanprasert May 1999

Screening Of Hepatitis C Virus Antibody In Hiv - Riskgroup: Comparison Between Hiv - Infectedsubjects And Hiv - Uninfected Subjects, P. Luksamijarukul, S. Tanprasert

Chulalongkorn Medical Journal

No abstract provided.


Formulations And Methods To Treat And Prevent Equine Protozoal Myeloencephalitis, David E. Granstrom, Thomas Tobin Mar 1999

Formulations And Methods To Treat And Prevent Equine Protozoal Myeloencephalitis, David E. Granstrom, Thomas Tobin

Veterinary Science Faculty Patents

The present invention provides formulations useful to treat EPM. It also provides methods to treat EPM in a horse in need of such treatment, comprising administering a pharmaceutically effective amount of a triazine-based anti-coccidial. Preferred are methods to treat EPM using clazuril, diclazuril, toltrazuril or letrazuril. The present invention also provides methods to prevent S. neurona infection in horses comprising administering a prophylactic amount of a triazine-based anticoccidial. Preferred is a method to prevent S. neurona infection by using clazuril, diclazuril, toltrazuril or letrazuril, alone or in combination with other known therapeutics.


Social Work Assessment Of Adaptive Functioning Using The Vineland Adaptive Behavior Scales: Issues Of Reliability And Validity, Peter Cabrera, Lucienne Grimes-Gaa, Bruce A. Thyer Jan 1999

Social Work Assessment Of Adaptive Functioning Using The Vineland Adaptive Behavior Scales: Issues Of Reliability And Validity, Peter Cabrera, Lucienne Grimes-Gaa, Bruce A. Thyer

Elián P. Cabrera-Nguyen

The assessment of client adaptive functioning is often an important component of a comprehensive social work evaluation. The Vineland Adaptive Behavior Scales (VABS) are the most commonly used quantitative measures of adaptive functioning for clients meeting the criteria for a wide range of disorders. We review the development of the VABS and current knowledge pertaining to the instrument's reliability and validity. We conclude that the ability to administer and interpret the VABS is an important skill for clinical social workers to acquire.


Evaluating Histories Of Substance Abuse In Cases Involving The Termination Of Parental Rights, Richard C. Boldt Jan 1999

Evaluating Histories Of Substance Abuse In Cases Involving The Termination Of Parental Rights, Richard C. Boldt

Journal of Health Care Law and Policy

No abstract provided.


Drug Treatment Courts: Evolution, Evaluation, And Future Directions, Gloria Danziger, Jeffrey A. Kuhn Jan 1999

Drug Treatment Courts: Evolution, Evaluation, And Future Directions, Gloria Danziger, Jeffrey A. Kuhn

Journal of Health Care Law and Policy

No abstract provided.


The Science Of Addiction: Research And Public Health Perspectives, Richard A. Millstein, Alan I. Leshner Jan 1999

The Science Of Addiction: Research And Public Health Perspectives, Richard A. Millstein, Alan I. Leshner

Journal of Health Care Law and Policy

No abstract provided.


Efficacy Of Moxidectin Against Gastrointestinal Nematodesin Naturally Infected Lambs And Calves, Erkut Tüzer, Müfi̇t Toparlak, Kazim Göksu Jan 1999

Efficacy Of Moxidectin Against Gastrointestinal Nematodesin Naturally Infected Lambs And Calves, Erkut Tüzer, Müfi̇t Toparlak, Kazim Göksu

Turkish Journal of Veterinary & Animal Sciences

In this trial based on the reduction of the egg output and on the evaluation of results from larval/egg differentiation, moxidectin (Cydectin, 1% injectable moxidectin) administrated subcutaneously at a dose of 0.2 mg kgbw -1 was found effective on the gastrointestinal nematodes in naturally infected lambs (8 female and 7 male treatment; 8 female and 7 male control) harbored Haemonchus spp, Ostertagia spp, Trichostrongylus spp and Nematodirus spp and in naturally infected female calves (20 treatment and 10 control) harbored Haemonchus spp, Ostertagia spp, Trichostrongylus spp, Bunostomum sppand Cooperia spp.The efficacy was 100% on day +7, 99.9% on day +14 …


Therapy Of Knemidocoptic Mange In Budgerigars With Spot-On Applicationof Moxidectin, Müfi̇t Toparlak, Erkut Tüzer, Ayşen Gargili, Aynur Gülanber Jan 1999

Therapy Of Knemidocoptic Mange In Budgerigars With Spot-On Applicationof Moxidectin, Müfi̇t Toparlak, Erkut Tüzer, Ayşen Gargili, Aynur Gülanber

Turkish Journal of Veterinary & Animal Sciences

In this study, 30 Budgerigars ( Melopsittacus undulatus) with Knemidocoptes pilae infection were treated with a spot-on application of moxidectin (Cydectin® Injection For Cattle) at a dose of 1 mg (0.1 ml Cydectin) per bird. This application was given once to 10 birds and twice at 10 days intervals to 20 birds. Clinical signs in all birds of both groups disappeared 30-40 days after treatment. No side effects were seen.


Myiasis Cases And Their Treatments In Cows, Sheep And Goats In Elazığ Province, Cem Ecmel Şaki̇, Edi̇p Özer Jan 1999

Myiasis Cases And Their Treatments In Cows, Sheep And Goats In Elazığ Province, Cem Ecmel Şaki̇, Edi̇p Özer

Turkish Journal of Veterinary & Animal Sciences

This study was carried out on cows, sheep and goats in Salkaya Village, Kovancılar, Baskıl and Sivrice towns and in Elazığ during 1994 and 1995. Fifty two myiasis cases were detected throughout the study. Forty seven (90.38%) and 5 (9.62%) of the cases were determined in sheep and cows respectively, no myiasis case was encountered in goats. Twenty two (42.32%) of the cases were seen in June during 1994 and 1995, 10 (19.23%) in May, 9 (17.31%) in July, 8 (15.38%) in September and 3 (5.77%) in August. Identification of the collected larvae showed that 51 (98.08%) and 1 (1.92%) …


Effects Of Megestrol Acetate Treatment On Dogs With Prolonged Estrus, Ayhan Baştan, Seli̇m Aslan Jan 1999

Effects Of Megestrol Acetate Treatment On Dogs With Prolonged Estrus, Ayhan Baştan, Seli̇m Aslan

Turkish Journal of Veterinary & Animal Sciences

A total of 22 dogs of different breeds with persistent estrus, between the ages of 1.5 and 6, were used. Diagnoses were made by anamnesis, general examination and vaginal smear. Vulvar edema, colour and volume of vaginal discharge, convolution of the mucosa and volume of secretion were recorded before and after treatment. Dogs were treated with 25 mg megestrol acetate (Niagestine, 25 mg/ml, Novo). Clinical manifestations disappeared within 3-7 days. Vaginal discharge ceased in 3.5±2.5 days and vulvar edema ceased in 3.5±1.6 days. In only one dog, the treatment was not effective after 15 days. The vulva was still swollen …


Cystic Fibrosis: Biological And Ethical Considerations, Sarah Elizabeth Milam Jan 1999

Cystic Fibrosis: Biological And Ethical Considerations, Sarah Elizabeth Milam

Honors Theses

Cystic fibrosis (CF) is a progressive, multisystem disease whose etiology is a genetic mutation in the CF gene product, cystic fibrosis transmembrane conductance regulator (CFTR). The disorder affects all exocrine glands, with common symptoms involving the lungs and pancreas. Although the CF gene and its protein product have been identified, two aspects of the disease make CF particularly difficult to diagnose and manage: (a) variability in both degree and pattern of the mutation in different individuals and (b) lack of information regarding the precise molecular and cellular mechanisms responsible. Let us begin by examining the pathogenesis and pathophysiology of the …


Screening For Colorectal Carcinoma, A. Rojanasakul Jan 1999

Screening For Colorectal Carcinoma, A. Rojanasakul

Chulalongkorn Medical Journal

No abstract provided.