Medicine and Health Sciences Commons^™

A Linkage Map Of The Canine Genome, Cathryn Mellersh, Amelia Langston, Gregory Acland, Melissa Fleming, Kunal Ray, Neil Weigand, Leigh Francisco, Mark Gibbs, Gustavo Aguirre, Elaine Ostrander

Gustavo D. Aguirre, VMD, PhD

Construction Of A Panel Of Canine–Rodent Hybrid Cell Lines For Use In Partitioning Of The Canine Genome, Amelia A. Langston, Cathryn S. Mellersh, Cassandra L. Neal, Kunal Ray, Gregory M. Acland, Mark Gibbs, Gustavo D. Aguirre, R.E. K. Fournier, Elaine A. Ostrander

Gustavo D. Aguirre, VMD, PhD

Further Characterization Of A Complement-Sensitive Mutant Of A Virulent Avian Escherichia Coli Isolate, Theodore J. Kottom, Lisa K. Nolan, Michael Robinson, John Brown, Tom Gustad, Shelley M. Horne, Catherine W. Giddings

Lisa K. Nolan

An attempt was made to characterize the mechanism of complement resistance operating in a virulent avian Escherichia coli isolate. Using flow cytometry to detect antibody to C3, we found that there was significantly more antibody bound to a complement-sensitive mutant of this wild type than to the parent organism, suggesting that more C3 subunits were bound to the wild type. Neither the wild type nor the mutant degraded C3. Further, the mutant was phagocytosed to a significantly greater degree than the wild type by cultured phagocytes in the presence of C5-deficient serum. These data suggest that the wild type is …

A Highly Adherent Phenotype Associated With Virulent Bvg+-Phase Swine Isolates Of Bordetella Bronchiseptica Grown Under Modulating Conditions, Karen B. Register, Mark R. Ackermann

Mark R. Ackermann

The ability of Bvg(-)-phase and Bvg(+)-phase Bordetella bronchiseptica swine isolates, grown under modulating or nonmodulating conditions, to adhere to swine ciliated nasal epithelial cells was determined. When virulent strains were cultivated at 37 degrees C in the Bvg+ phase, numerous adherent bacteria (approximately eight per cell, depending on the strain used) were observed. However, when such strains were grown under modulating conditions (23 degrees C), a significant increase in the level of attachment was seen, suggesting that B. bronchiseptica produces a Bvg-repressed adhesin under these conditions. bvg mutant strains, including an isogenic bvgS mutant, adhered minimally. Western blots indicated that …

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Signal Transduction: Rhomantic Interludes Raise Blood Pressure, Andrew P. Somlyo

Jama S. Coartney

No abstract provided.

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Sequential Expression Of Egr-1 And Egr-3 In Hippocampal Granule Cells Following Electroconvulsive Stimulation, Kevin O'Donovan

Kevin O'Donovan

No abstract provided.

The Placebo Effect, Charles Weijer

Charles Weijer

No abstract provided.

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Spiroplasma Lineolae Sp. Nov., From The Horsefly Tabanus Lineola (Diptera : Tabanidae), Frank E. French, Robert F. Whitcomb, Joseph G. Tully, Patricia Carle, Joseph M. Bové, Roberta B. Henegar, Jean R. Adams, Gail E. Gasparich, David L. Williamson

Gail Gasparich

Collaborative Roles For C-Jun N-Terminal Kinase, C-Jun, Serum Response Factor, And Sp1 In Calcium-Regulated Myocardial Gene Expression, Patrick M. Mcdonough, Deanna S. Hanford, Amy B. Sprenkle, Noel R. Mellon, Christopher C. Glembotski

Amy Sprenkle

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Entrapped Lip Following Sport Injury, W.C. Ngeow, L. Kon

Wei Cheong Ngeow

A case is presented of a patient whose lip became entrapped onto his orthodontic bracket following a blow to his face during a contact sport. The entrapped mucosa had to be released surgically.

Effects Of Pasteurella Multocida Toxin On Porcine Bone Marrow Cell Differentiation Into Osteoclasts And Osteoblasts, S. M. Gwaltney, R. J. S. Galvin, K. B. Register, R. B. Rimler, Mark R. Ackermann

Mark R. Ackermann

The effect of Pasteurella multocida toxin (PMT) on porcine osteoclast and osteoblast differentiation was studied using in vitro cell culture systems. When grown in the presence of Vitamin D3, isolated porcine bone marrow cells formed multinucleated cells with features characteristic of osteoclasts. Exposure of bone marrow cells to Vitamin D3 and PMT during growth resulted in formation of increased numbers and earlier appearance of osteoclasts compared to controls. Ultrafiltered medium from PMT-treated cells likewise increased osteoclast numbers, suggesting that a soluble mediator may be involved in the action of PMT. When cell cultures were treated with fluorescein-labeled PMT, fluorescence was …

Iron Regulatory Protein 1 Is Not Required For The Modulation Of Ferritin And Transferrin Receptor Expression By Iron In A Murine Pro-B Lymphocyte Cell Line, Kevin Schalinske, Kenneth P. Blemings, Daniel W. Steffen, Opal S. Chen, Richard S. Eisenstein

Kevin Schalinske

Iron regulatory proteins (IRPs) are cytoplasmic RNA binding proteins that are central components of a sensory and regulatory network that modulates vertebrate iron homeostasis. IRPs regulate iron metabolism by binding to iron responsive element(s) (IREs) in the 5* or 3* untranslated region of ferritin or transferrin receptor (TfR) mRNAs. Two IRPs, IRP1 and IRP2, have been identified previously. IRP1 exhibits two mutually exclusive functions as an RNA binding protein or as the cytosolic isoform of aconitase. We demonstrate that the BayF3 family of murine pro-B lymphocytes represents the first example of a mammalian cell line that fails to express IRP1 …

Do Patients With Breast Cancer Participating In Clinical Trials Receive Better Nursing Care?, Myriam Skrutkowska, Charles Weijer

Charles Weijer

PURPOSE/OBJECTIVES: To examine differences in nursing care received by patients with breast cancer enrolled in clinical trials and those not enrolled in clinical trials.

DESIGN: Retrospective review of clinic charts.

SETTING: Oncology outpatient department of a tertiary-care hospital. SAMPLE: 90 women with early stage breast cancer. The mean age of the women was 53 years. More than half of the women (51 of 90) were treated in a clinical trial.

METHODS: Retrospective chart review of all the nurse-patient clinic encounters for a six-month period from date of cancer diagnosis. The content of each encounter was coded using a modified version …

Canadians Dying For Health Care Technology?, Deborah Fitzsimmons

Deborah A Fitzsimmons

No abstract provided.

He Who Has Seen The Wind: The Black Bonspiel Of Willie Maccrimmon, Don Morrow

Donald Morrow

No abstract provided.

Canine Rod Photoreceptor Cgmp-Gated Channel Protein Α-Subunit: Studies On The Expression Of The Gene And Characterization Of The Cdna, Qi Zhang, Sue Pearce-Kelling, Gregory Acland, Gustavo Aguirre, Kunal Ray

Gustavo D. Aguirre, VMD, PhD

Dominican College's Nursing Senior Project (Poster), Luanne Linnard-Palmer

Luanne Linnard-Palmer

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A Conceptual Model Of The Corporate Decision-Making Process Of Sport Sponsorship Acquisition, David Arthur, Don Scott, Terry Woods

Terry Woods

The general acceptance of sport sponsorship by corporate and sporting worlds alike has led to a situation whereby corporations receive from hundreds to thousands of unsolicited proposals annually. Despite this, there is a general lack of systematic research into sport sponsorship with little information in existence as to how corporations decide between alternative properties. In an attempt to address this situation, this paper develops a conceptual model of the sport sponsorship acquisition process based on the basic tenets of organizational purchasing behavior, contemporary literature on sport sponsorship, and the results of a qualitative study. It is anticipated that the Sport …

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The Use Of Gutta-Percha Point To Locate The Origin Of Facial Sinus, W.C. Ngeow

Wei Cheong Ngeow

Infection from the wisdom teeth usually causes severe swelling at the region of the angle and body of the mandible. Occasionally, it tracts outward to form a cervicofacial sinus. This paper demonstrates the use of gutta-percha point to locate the origin of a cervicofacial sinus due to an asymptomatic impacted wisdom tooth. The advantage of using gutta-percha point is discussed.

Effect Size And Power For Clinical Trials Using Years Of Healthy Life As The Primary Endpoint, Paula Diehr

Paula Diehr

Some clinical trials perform repeated measurements on patients over time, plot those measures against time, and summarize the results in terms of the area under the curve. If the measured variable is health status, the summary outcome is sometimes referred to as years of healthy life (YHL), or quality-adjusted life years (QALY). This paper investigates some theoretical and practical aspects of randomized trials designed to assess measures such as YHL. We first derived algebraic expressions for the effect size of YHL measures under several theoretical models of the treatment's effect on health. We used these expressions to examine how the …