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Articles 1 - 15 of 15
Full-Text Articles in Medicine and Health Sciences
Jefferson Alumni Bulletin – Volume Xlv, Number 1, December 1995
Jefferson Alumni Bulletin – Volume Xlv, Number 1, December 1995
The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)
Jefferson Alumni Bulletin – Volume XLV, Number 1, December 1995
We will fight cancer with molecular therapeutics and prediagnostics, page 4
Behavior and economics will challenge prevention, page 6
From genetic understanding to cure, page 9
Computer-based teaching reshapes how students learn, page 12
Will tomorrow’s journals be electronic? Page 14
Jefferson health system upgrades its information technology, page 17
Molecule essential for cell growth and division is discovered at Jeff, page 19
Stimulation Of Alpha 1(I) Procollagen Gene Expression In Nih-3t3 Cells By The Human T Cell Leukemia Virus Type 1 (Htlv-1) Tax Gene., E. Munoz, D. Suri, S. Amini, K. Khalili, Sergio A. Jimenez
Stimulation Of Alpha 1(I) Procollagen Gene Expression In Nih-3t3 Cells By The Human T Cell Leukemia Virus Type 1 (Htlv-1) Tax Gene., E. Munoz, D. Suri, S. Amini, K. Khalili, Sergio A. Jimenez
Selected Works of Sergio Jiménez, MD, MACR
The mechanisms that regulate the expression of genes encoding extracellular matrix proteins in fibroblasts and other mesenchymal cells have remained elusive. Studies from several laboratories have indicated that Tax, a trans-regulatory protein from the human T cell leukemia virus type I not only augments viral gene expression but also triggers the expression of various cellular genes. Here, we examined the hypothesis that the expression of collagen genes may also be modulated by Tax. NIH-3T3 cells were simultaneously transfected with a Tax expressor plasmid and a chimeric construct containing regulatory sequences (-804 to +42 bp) of the alpha 1(I) procollagen gene …
Nurses Alumni Association Bulletin, Fall 1995, Alice C. Boehret, Eleanor Kowaleski Larson, Nancy Powell, Dorothy R. Long, Pamela G. Watson, Betty Piersol, Margaret Summers, Sara Entriken, Jane Ryan Dietrich, Paula J. Levine, Lorraine Mccall, Doris E. Bowman, Linda Meachum Scheetz, Mary Kulys, Ethel Gillette
Nurses Alumni Association Bulletin, Fall 1995, Alice C. Boehret, Eleanor Kowaleski Larson, Nancy Powell, Dorothy R. Long, Pamela G. Watson, Betty Piersol, Margaret Summers, Sara Entriken, Jane Ryan Dietrich, Paula J. Levine, Lorraine Mccall, Doris E. Bowman, Linda Meachum Scheetz, Mary Kulys, Ethel Gillette
Nursing Alumni Bulletins
1995-1996 Meeting Dates Calendar
1996 Annual Luncheon-Meeting Notice
Officers and Committee Chairs
Bulletin Publication Committee
1995-1996 Meeting Dates Calendar
The President's Message
Financial Report
What's New
Fiftieth Anniversary
Resume of Minutes of Alumni Association Meetings
Scholarship Funds at Work
CAHS Alumni Board/Diploma School
Alumni Office News
Jefferson Health System
Oldest Veteran Dies
1OOth Anniversary
Pearl Harbor Remembered
"Memories"
Janet Hindson Retires
Happy Birthday
Scholarship Fund donors for 1994
Committee Reports
By-Laws
Development
Bulletin
Relief Fund
Satellite
Social
Scholarship
In Memoriam, Names of Deceased Graduates
Class News
Luncheon Photos
Jefferson Alumni Identification Card
The Diploma School of Nursing Alumni Association-Mabel C. …
Impact Of Spinal Cord Injury On The Life Roles Of Women., M Claire Quigley
Impact Of Spinal Cord Injury On The Life Roles Of Women., M Claire Quigley
Department of Occupational Therapy Faculty Papers
This qualitative study was conducted to explore and describe the role experience of five women whose lives were disrupted by a traumatic spinal cord injury and who later returned to their communities after completing intensive rehabilitation programs. In-depth interviews and participant observations were used to examine the experiences of these women. The findings exemplify how the women's use of adaptation and negotiation and the development of a new role as self-advocate facilitated the reestablishment of their life roles. As the women's occupational roles were redefined, the processes of adaptation and negotiation were evident in three aspects of their lives: daily …
Computer-Assisted Instruction As A Learning Resource For Applied Anatomy And Kinesiology In The Occupational Therapy Curriculum., Susan Toth-Cohen
Computer-Assisted Instruction As A Learning Resource For Applied Anatomy And Kinesiology In The Occupational Therapy Curriculum., Susan Toth-Cohen
Department of Occupational Therapy Faculty Papers
OBJECTIVES: The purpose of these studies was to examine the learning outcomes of a computer-assisted instruction (CAI) tutorial in applied anatomy and kinesiology for occupational therapy students and to determine its applicability for use in two university settings.
METHOD: Two separate pilot studies were conducted at two universities. In each study, the learning outcomes of an experimental group of occupational therapy students using a CAI program and a control group using books to study the same material were compared. Learning outcomes were assessed with post-test achievement test scores on an applied anatomy and kinesiology test and responses to an attitude …
Anti-Human Immunodeficiency Virus (Hiv) Activities Of Halogenated Gomisin J Derivatives, New Nonnucleoside Inhibitors Of Hiv Type 1 Reverse Transcriptase, Toshiaki Fujihashi, Hiroto Hara, Toshiya Sakata, Kazuya Mori, Hirotaka Higuchi, Akio Tanaka, Hideko Kaji, Akira Kaji
Anti-Human Immunodeficiency Virus (Hiv) Activities Of Halogenated Gomisin J Derivatives, New Nonnucleoside Inhibitors Of Hiv Type 1 Reverse Transcriptase, Toshiaki Fujihashi, Hiroto Hara, Toshiya Sakata, Kazuya Mori, Hirotaka Higuchi, Akio Tanaka, Hideko Kaji, Akira Kaji
Department of Biochemistry and Molecular Biology Faculty Papers
Halogenated gomisin J (a derivative of lignan compound), represented by the bromine derivative 1506 [(6R, 7S, S-biar)-4,9-dibromo-3,10-dihydroxy-1,2,11,12-tetramethoxy-6, 7-dimethyl-5,6,7,8- tetrahydrodibenzo[a,c]cyclo-octene], was found to be a potent inhibitor of the cytopathic effects of human immunodeficiency virus type 1 (HIV-1) on MT-4 human T cells (50% effective dose, 0.1 to 0.5 microM). Gomisin J derivatives were active in preventing p24 production from acutely HIV-1-infected H9 cells. The selective indices (toxic dose/effective dose) of these compounds were as high as > 300 in some systems. 1506 was active against 3'-azido-3'-deoxythymidine-resistant HIV-1 and acted synergistically with AZT and 2',3'-ddC. 1506 inhibited HIV-1 reverse transcriptase (RT) in …
Jefferson Alumni Bulletin – Volume Xliv, Number 4, September 1995
Jefferson Alumni Bulletin – Volume Xliv, Number 4, September 1995
The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)
Jefferson Alumni Bulletin – Volume XLIV, Number 4, September 1995 Anniversary galas, page 4 and 24 Jefferson health system in established by the university and main line health, page 12 Research, page 14 Appointments, page 20 Books, page 22 Journal of neurovirology is founded, page 22
Department Of Radiology-Annual Report-July 1, 1994 To June 30, 1995, David C. Levin
Department Of Radiology-Annual Report-July 1, 1994 To June 30, 1995, David C. Levin
Department of Radiology Administrative Documents and Reports
Department of Radiology Annual Report, July 1, 1994 to June 30, 1995. Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States. 120 pages.
Increased Abundance Of The Receptor-Type Protein-Tyrosine Phosphatase Lar Accounts For The Elevated Insulin Receptor Dephosphorylating Activity In Adipose Tissue Of Obese Human Subjects, Falyaz Ahmad, Robert V. Considine, Barry J. Goldstein
Increased Abundance Of The Receptor-Type Protein-Tyrosine Phosphatase Lar Accounts For The Elevated Insulin Receptor Dephosphorylating Activity In Adipose Tissue Of Obese Human Subjects, Falyaz Ahmad, Robert V. Considine, Barry J. Goldstein
Department of Medicine Faculty Papers
Protein-tyrosine phosphatases (PTPases) have an essential role in the regulation of the steady-state phosphorylation of the insulin receptor and other proteins in the insulin signalling pathway. To examine whether increased PTPase activity is associated with adipose tissue insulin resistance in human obesity we measured PTPase enzyme activity towards the insulin receptor in homogenates of subcutaneous adipose tissue from a series of six lean and six nondiabetic, obese (body mass index > 30) subjects. The obese subjects had a mean 1.74-fold increase in PTPase activity (P < 0.0001) with a striking positive correlation by linear regression analysis between PTPase activity and body mass index among all of the samples (R = 0.918; P < 0.0001). The abundance of three candidate insulin receptor PTPases in adipose tissue was also estimated by immunoblot analysis. The most prominent increase was a 2.03-fold rise in the transmembrane PTPase LAR (P < 0.001). Of the three PTPase examined, only immunodepletion of LAR protein from the homogenates with neutralizing antibodies resulted in normalization of the PTPase activity towards the insulin receptor, demonstrating that the increase in LAR was responsible for the enhanced PTPase activity in the adipose tissue from obese subjects. These studies suggest that increased PTPase activity towards the insulin receptor is a pathogenetic factor in the insulin resistance of adipose tissue in human obesity and provide evidence for a potential role of the LAR PTPase in the regulation of insulin signalling in disease states.
1995 Commencement For College Of Allied Health Sciences
1995 Commencement For College Of Allied Health Sciences
Jefferson College of Nursing Commencements
No abstract provided.
Increased Alpha 1(I) Procollagen Gene Expression In Tight Skin (Tsk) Mice Myocardial Fibroblasts Is Due To A Reduced Interaction Of A Negative Regulatory Sequence With Ap-1 Transcription Factor., Neena Philips, Reza I. Bashey, Sergio A. Jimenez
Increased Alpha 1(I) Procollagen Gene Expression In Tight Skin (Tsk) Mice Myocardial Fibroblasts Is Due To A Reduced Interaction Of A Negative Regulatory Sequence With Ap-1 Transcription Factor., Neena Philips, Reza I. Bashey, Sergio A. Jimenez
Department of Medicine Faculty Papers
The TSK mouse, a model of fibrosis, displays exaggerated connective tissue accumulation in skin and visceral organs including the heart. To study the mechanisms of myocardial fibrosis in TSK mice, we established several strains of TSK mice myocardial fibroblasts in culture and examined the regulation of collagen gene expression in these cells. These strains displayed increased collagen gene expression in comparison with myocardial fibroblasts established from normal mice. On an average, the TSK myocardial fibroblast cultures showed a 4-fold increase in collagen synthesis and 4.4- and 3.6-fold increases, respectively, in alpha 1(I) and alpha 1(III) collagen mRNA steady state levels. …
Jefferson Alumni Bulletin – Volume Xliv, Number 3, Spring 1995
Jefferson Alumni Bulletin – Volume Xliv, Number 3, Spring 1995
The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)
Jefferson Alumni Bulletin – Volume XLIV, Number 3, Spring 1995
A brief history, page 4
Then and now, page 9
Views of the campus, page 14
Jefferson facts, page 14
A host of remarkable graduates, page 17
Jefferson looks to the future, page 20
Mentorship Experiences In A Group Of Occupational Therapy Leaders., Ruth Levine Schemm, Theodore Bross
Mentorship Experiences In A Group Of Occupational Therapy Leaders., Ruth Levine Schemm, Theodore Bross
Department of Occupational Therapy Faculty Papers
OBJECTIVES: The development of occupational therapy leaders is a long-held goal of many members of the American Occupational Therapy Association and of state associations. The initiation of mentor programs is a common means to accomplish this goal. These programs take time and effort, and, although occupational therapists have described how mentorship programs work in the literature, there are few articles that describe the actual mentorship experiences of occupational therapy leaders.
METHOD: To study the experiences of elected occupational therapy leaders, a 30-item questionnaire was distributed at the annual meeting of the Committee of State Association Presidents and completed by 53 …
Jefferson Alumni Bulletin – Volume Xliv, Number 2, Winter 1994-1995
Jefferson Alumni Bulletin – Volume Xliv, Number 2, Winter 1994-1995
The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)
Jefferson Alumni Bulletin – Volume XLIV, Number 2, Winter 1994-1995 College of allied health sciences and medical college collaborate, page 4 Diabetes prevention study, page 6 With outside funding, JeffCARES becomes part of curriculum, page 10 JeffMOMS Teaches freshmen, page 11 Students come by many routes to Jefferson, page 12 West Jersey health system joins Jefferson in healthshare group, page 15 Working on health care reform, page 22 Books, page 14 Bone marrow transplant center established under Flomenberg, page 16 Farber chairs board of trustees, page 16 Spitzer is pediatrics chair, page 17 Neurosensory institute’s unusual surgery saves infant, page …
Randomized Trial Of Erythromycin And Azithromycin For Treatment Of Chlamydial Infection In Pregnancy., M F Rosenn, G A Macones, N S Silverman
Randomized Trial Of Erythromycin And Azithromycin For Treatment Of Chlamydial Infection In Pregnancy., M F Rosenn, G A Macones, N S Silverman
Department of Obstetrics and Gynecology Faculty Papers
OBJECTIVE: The purpose of this study was to compare erythromycin and azithromycin in the treatment of chlamydial cervicitis during pregnancy with regard to efficacy, side effects, and compliance.
METHODS: In a prospective manner, 48 pregnant patients with cervical chlamydial infections diagnosed by routine screening tests were randomly assigned to receive either erythromycin, 500 mg q.i.d. for 7 days (N = 24), or azithromycin, 1 g as a one-time dose (N = 24). All sexual partners were given prescriptions for doxycycline, 100 mg b.i.d. for 7 days. The treatment efficacy was assessed by follow-up chlamydia testing 3 weeks after the therapy …