Medicine and Health Sciences Commons^™

Intra-Articular Lavage Using Dimethyl Sulfoxide In The Clinically Normal Equine, Henry Adair, Dallas Goble, S Vanhooser, James Blackford, Barton Rohrbach

James T. Blackford DVM, MS, DACVS

No abstract provided.

Investigation Of The Optimal Load-Bearing Characteristics Of Patellar Tendon Bearing (Ptb) Prostheses, Rahamim Seliktar, Theerasakdi Vachranukunkiet, Marcus P. Besser, Denise Kuenzig, A. Esquenazi

Department of Physical Therapy Faculty Papers

The long-term goal of the research team is to automate the construction of lower limb prostheses using computer integrated manufacturing (CIM) techniques.

Volume 32, Index, Canadian Medical Association

Canadian Journal of Surgery

The mission of CJS is to contribute to the effective continuing medical education of Canadian surgical specialists, using innovative techniques when feasible, and to provide surgeons with an effective vehicle for the dissemination of observations in the areas of clinical and basic science research.

Visit the journal website at http://canjsurg.ca/ for more.

Novel Method Of Administering Aspirin And Dosage Forms Containing Same, Anwar A. Hussain, Lewis W. Dittert, Thomas S. Foster

Pharmaceutical Sciences Faculty Patents

The invention relates to a novel method of administering aspirin to achieve improved delivery thereof. The invention further relates to novel dosage forms of neutralized aspirin adapted for nasal administration, such as solutions, suspensions, gels and ointments. These dosage forms find utility in the treatment of conditions known to respond to the administration of aspirin, particularly in the treatment of migraine and in the mitigation of cardiovascular damage resulting from heart attack.

Texas D.O. Volume 46, Number 11, Texas Osteopathic Medical Association

Texas Osteopathic Physicians Journal

No abstract provided.

Morality Versus Slogans, Bernard Gert

Center for the Study of Ethics in Society Papers

Presented to the WMU Center for the Study of Ethics in Society, April 1, 1988.

Dengue Virus-Specific Cross-Reactive Cd8+ Human Cytotoxic T Lymphocytes, Jack F. Bukowski, Ichiro Kurane, Ching-Juh Lai, Michael Bray, Barry Falgout, Francis A. Ennis

Open Access Articles

Stimulation with live dengue virus of peripheral blood mononuclear cells from a dengue virus type 4-immune donor generated virus-specific, serotype-cross-reactive, CD8+, class I-restricted cytotoxic T lymphocytes (CTL) capable of lysing dengue virus-infected cells and cells pulsed with dengue virus antigens of all four serotypes. These CTL lysed autologous fibroblasts infected with vaccinia virus-dengue virus recombinant viruses containing the E gene or several nonstructural dengue virus type 4 genes. These results demonstrate that both dengue virus structural and nonstructural proteins are targets for the cytotoxic T-cell-mediated immune response to dengue virus and suggest that serotype-cross-reactive CD8+ CTL may be important mediators ...

Update - December 1989, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Australia's Herbert Clifford will lecture at Loma Linda on February 24
-- Claremont Conference endorses "The Right to Choose Death"
-- Michael and Helen Pearson arrive from England
-- Contributors receive monthly audio cassettes

[ Nancy Cruzan and the Courts ]
-- The Persistent Vegetative State
-- Nancy Cruzan is Already Dead
-- Nancy Cruzan is Not a Vegetable
-- My Family's Anguish

-- The Right to Choose Death

Leisure Satisfaction Of Alcoholics And Cocaine Addicts, Tamera F. Stanback

Master's Theses

A role for occupational therapists is to help substance abuse clients achieve a healthy balance across occupational performance areas, including leisure. The literature suggests that alcoholics have deficits in leisure, but cocaine addicts have not yet been studied systematically in terms of leisure. This study compared twenty alcoholics from two Midwestern in-patient treatments centers to fourteen unmatched cocaine addicts at the same centers in terms of their leisure satisfaction. Then, nine male subjects from each group were matched in terms of age and family status, and t-test comparisons were made once again. The Leisure Satisfaction Scale was used as a ...

Continuous Passive Motion After Knee Arthroscopy, Lisa Bauman

Master's Theses

The purpose of the study was to investigate the effect of continuous passive motion (CPM) after arthroscopy. A CPM machine was used one hour following knee surgery. Statistical analysis was performed to determine differences in knee range of motion (ROM), strength and circumference, at time intervals preoperatively, one, seven, and twenty-eight days following surgery. The analysis of variance revealed no significant difference between the CPM and control groups for any parameter. A significant interaction effect between treatment and time was demonstrated one day after surgery for extension, joint line circumference, and midthigh circumference; and 28 days after surgery for the ...

An Investigation Of Pitch Perturbation And Vocal Intensity Characteristics Of Stutterers And Nonstutterers, Carmen M. Bamberg

Master's Theses

Pitch and amplitude perturbation values were compared for nine adult stutterers and nine adult nonstutterers. Each subject produced ten sustained phonations of the vowels /a/ and /i/. An automatic pitch-synchronous autocorrelation fundamental frequency tracker was used to extract period and amplitude measures.

Findings revealed that: (a) stutterers had significantly more vocal shimmer than nonstutterers (p = .01), (b) F-ratios for percent jitter between groups approached (p = .07) but did not reach significance, and (c) the vowel /a/ was produced with higher levels of jitter and shimmer than the vowel /i/. Results support the notion that instability of the vocalization process is ...

The Effects Of Added Purpose On Fine Motor Performance In Learning Disabled Children, Sarah Lynn Austin

Master's Theses

The idea that occupations which offer added levels of purpose elicit a high quality of performance is widely accepted within occupational therapy. In this experiment involving fine motor performance, fifty-three learning disabled children were randomly assigned to two groups. It was hypothesized that children cutting out a circle, presented as a wheel which would complete a paper truck, would cut more accurately than those who cut out the same circle without the suggestion of it being used as a wheel. Accuracy was assessed by measuring the area of the children's cutting errors. The experimental design included the use of ...

Simian Virus 40 Host Range/Helper Function Mutations Cause Multiple Defects In Viral Late Gene Expression., Terryl Stacy, Michele Chamberlain, Charles N. Cole

Open Dartmouth: Faculty Open Access Articles

Simian virus 40 (SV40) deletion mutants dlA2459 and dlA2475 express T antigens that lack the normal carboxy terminus. These mutants are called host range/helper function (hr/hf) mutants because they form plaques at 37 degrees C on BSC-1 and Vero monkey kidney cell lines but not on CV-1p monkey kidney cells. Wild-type SV40 can provide a helper function to permit growth of human adenoviruses in monkey kidney cells; the hr/hf mutants cannot. Progeny yields of hr/hf mutants are also cold sensitive in all cell lines tested. Patterns of viral macromolecular synthesis in three cell lines (Vero, BSC-1 ...

Health Effects Of Air Pollutants (Sulfur Dioxide, Ozone, And Carbon Monoxide), Robert A. Bethel

Air Quality Protection in the West (November 27-28)

19 pages (includes illustrations).

Contains references.

To The U.S. Department Of Transportation: Comments Of The Environmental Defense Fund On The Secretary Of Transportation’S National Transportation Policy, Robert E. Yuhnke

Air Quality Protection in the West (November 27-28)

20 pages.

Agenda: Air Quality Protection In The West, University Of Colorado Boulder. Natural Resources Law Center

Air Quality Protection in the West (November 27-28)

Conference organizers, session moderators and/or speakers included University of Colorado School of Law professor Mark S. Squillace.

Visibility, acid rain, air toxics, and urban air pollution are the topics of an upcoming Center conference on air quality in the West. The conference will be held at the School of Law in Boulder on November 27-28, 1989. Presentations will describe the nature and scope of the issues, the existing legal framework and experience with its implementation, and proposed changes in the law. Emphasis will be placed on air quality issues in the West and efforts underway to address these problems ...

Toxic Air Pollution: New Solutions To Old Problems, Devra Lee Davis, Curtis Moore

Air Quality Protection in the West (November 27-28)

12 pages.

Post-Transcriptional Regulation Of Glutathione Peroxidase Gene Expression By Selenium In The Hl-60 Human Myeloid Cell Line, Sunil Chada, Constance Whitney, Peter E. Newburger

Open Access Articles

We have used a cloned cDNA for the major human selenoprotein, glutathione peroxidase (GPx), to assess the mode of regulation of human GPx gene (GPX-1) expression by selenium. When the HL-60 human myeloid cell line is grown in a selenium-deficient medium, GPx enzymatic activity decreases 30-fold compared with selenium-replete cells. Upon return to a medium containing selenium in the form of selenite, GPx activity in the cells starts to increase within 48 hours and reaches maximal (selenium-replete) levels at 7 days. Steady-state immunoreactive protein levels correlate with enzymatic activity. Cycloheximide inhibits the rise in GPx activity that accompanies selenium replenishment ...

Correspondence - Resolution 89-3-F, Amos Gott, Howard Bailey, Charles Kupchella, Kevin Charles

Student Government Association

Correspondence regarding Resolution 89-3-F requesting AIDS, HIV and sexually transmitted disease education.

Texas D.O. Volume 46, Number 10, Texas Osteopathic Medical Association

Texas Osteopathic Physicians Journal

No abstract provided.

Humanae Vitae, Natural Law, And Catholic Moral Thought, William E. May

The Linacre Quarterly

No abstract provided.

Comparisons Of Cutoff And Regression-Based Definitions Of Reading Disabilities, J. M. Fletcher, K. A. Espy, D. J. Francis, K. C. Davidson, B. P. Rourke, S. A. Shaywitz

Developmental Cognitive Neuroscience Laboratory - Faculty and Staff Publications

Investigated specificity in reading disability by comparing 2 approaches to defining and selecting children with reading disabilities. One approach defined reading disability according to cutoff scores representing appropriate levels of intelligence and reading deficiency, whereas the other approach adjusted these scores for their intercorrelation through regression procedures. Results reveal differences in which of 1,069 children (aged 9-14 yrs) were identified as reading disabled, depending on the definition used. However, differences in neuropsychological performance between Ss whose reading scores were discrepant or not discrepant with their IQ scores were small and nonspecific for both definitions.

Occupational Therapy In Early Intervention: A Family-Centered Approach., Roseann C. Schaaf, L L. Mulrooney

Department of Occupational Therapy Faculty Papers

This article describes a framework for occupational therapy service provision in early intervention settings and presents pilot data aimed at examining the framework's effectiveness. The Family-Centered Framework for Early Intervention is a synthesis of concepts from the Model of Human Occupation (Kielhofner & Burke, 1980) and from the literature on play. It encompasses a systematic, holistic approach that considers the child and the family within the context of their life environments. In this framework, play is used both as an evaluative tool and as an intervention modality that addresses the volition, habituation, and performance of the child and family as ...

Breast Cancer Screening By Mammography: Utilization And Associated Factors, Jane G. Zapka, Anne M. Stoddard, Mary E. Costanza, Harru L. Greene Jr.

Women’s Health Research Faculty Publications

The status of mammography screening experience and factors related to utilization were examined in six towns serviced by physician staffs at five hospitals. Data were collected via random digit dial telephone interview of a probability sample of 1184 women, aged 45-75 years. The results showed that 55% of the women reported ever having had a mammogram. Of those who had ever had a mammogram, 21% reported that the mammogram in the past year was their first one. Of those women who are over 50 and had ever had a mammogram, 57% reported one in the past year. Analyses demonstrated that ...

Significance Of Premature Stop Codons In Env Of Simian Immunodeficiency Virus, Toshiaki Kodama, Dawn P. Wooley, Yathirajulu M. Naidu, Harry W. Kestler Iii, Muthiah D. Daniel, Yen Li, Ronald C. Desrosiers

Neuroscience, Cell Biology & Physiology Faculty Publications

The location of the translational termination codon for the transmembrane protein (TMP) varies in three infectious molecular clones of simian immunodeficiency virus from macaques (SIV_mac). The SIV_mac251 and SIV_mac142 infectious clones have premature stop signals that differ in location by one codon; transfection of these DNAs into human HUT-78 cells yielded virus with a truncated TMP (28 to 30 kilodaltons [kDa]). The SIV_mac239 infectious clone does not have a premature stop codon in its TMP-coding region. Transfection of HUT-78 cells with this clone initially yielded virus with a full-length TMP (41 kDa). At ...

Uwomj Volume 59, No 1, November 1989, Western University

University of Western Ontario Medical Journal

Schulich School of Medicine & Dentistry

Complex Motor Dynamics And Control In Multi-Looped Negative Feedback Systems, Anne Beuter, John Milton, Christiane Labrie, Leon Glass

WM Keck Science Faculty Papers

Experiments were performed in normal and Parkinsonian subjects who were asked to maintain a constant finger position using time-delayed visual feedback. The finger position showed complex dynamics, with characteristic differences between normal and Parkinosonian subjects. Here we discuss some of the theoretical issues that must be resolved in order to understand the mechanisms that underlie the generation of these complex signals.

Volume 32, Issue 6, Canadian Medical Association

Canadian Journal of Surgery

The mission of CJS is to contribute to the effective continuing medical education of Canadian surgical specialists, using innovative techniques when feasible, and to provide surgeons with an effective vehicle for the dissemination of observations in the areas of clinical and basic science research.

Visit the journal website at http://canjsurg.ca/ for more.

Update - November 1989, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Character, Virtue, and Self-Interest in the Ethics of the Professions (Excerpts from the Second Annual Jack W. Provonsha Lecture)
-- Minnesota Bioethics Retreat and Conference

Linker Insertion Mutants Of Simian Virus 40 Large T Antigen That Show Trans-Dominant Interference With Wild-Type Large T Antigen Map To Multiple Sites Within The T-Antigen Gene., Jiyue Y. Zhu, Charles N. Cole

Open Dartmouth: Faculty Open Access Articles

Linker insertion mutants affecting the simian virus 40 (SV40) large tumor (T) antigen were constructed by inserting a 12-base-pair oligonucleotide linker into restriction endonuclease cleavage sites located within the early region of SV40. One mutant, with the insertion at amino acid 5, was viable in CV-1p and BSC-1 cells, indicating that sequences very close to the amino terminus of large T could be altered without affecting the lytic infection cycle of SV40. All other mutants affecting large T were not viable. In complementation assays between the linker insertion mutants and either a late-gene mutant, dlBC865, or a host range/helper ...