Medicine and Health Sciences Commons^™

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

The Effectiveness Of Oxandrolone In Promoting Linear Growth In Growth Hormone Deficient Children, Charles B. Wolf, Raymond C. Mellinger, Lewis B. Morrow, M. Saeed-Uz Zafar

Henry Ford Hospital Medical Journal

This two-year study consisted of a comparison of oxandrolone and growth hormone for the treatment of five children with documented growth hormone deficiency. Previously, androgens have been reported to be relatively ineffective in accelerating linear growth In growth hormone deficient children. Oxandrolone was administered for one year. Growth hormone was added in the second six months and then was given as a single agent in the third six months. Growth accelerated markedly in all patients. Only one child showed more rapid growth with the addition of growth hormone while two children actually grew more rapidly under the Influence of oxandrolone …

Surgical Treatment Of Liver Trauma: Technical Considerations And Case Reports, C. Grodsinsky, T. A. Fox Jr., B. E. Brush

Henry Ford Hospital Medical Journal

The incidence of abdominal trauma, and thus that of liver trauma, has been increasing in the past few years. Improvements in the understanding of the anatomy of the liver and improvements in diagnostic techniques have resulted in shorter and better operations with less delay between injury and surgery. Improvements in transportation to adequate hospital facilities and vigorous resuscitative measures have also contributed to lowering the mortality rate for this type of injury. Suggestions are made for the surgical management of liver injuries, together with illustrative case reports.

Near Basal Blood Pressure: A Method Applicable To Clinical Practice, John R. Caldwell

Henry Ford Hospital Medical Journal

A method is described for determining near basal blood pressure (NBBP) measurements that is applicable to outpatient clinic or office use in daily practice. In our clinic, patients' mean casual pressure was significantly higher than the NBBP, the difference being 40 mm Hg systolic (p < .001) and 18 mm Hg diastolic (p < .001). In hospitalized patients the casual blood pressure was higher than the fourth to sixth day hospital average, and the hospital average was higher than NBBP. The difference between the last two was 15 mm Hg systolic (p <. 005) and 9 mm Hg diastolic (p < .005). In patients recording blood pressure readings at home the average weekly home-recorded blood pressure was not significantly different from NBBP during the same week, -1 mm Hg systolic (p > .80) and 4 mm Hg diastolic (p > .10). NBBP by this method offers a practical way to estimate the average daily blood pressure.

Electrical Alternans In Cardiac Tamponade, Andreas P. Niarchos

Henry Ford Hospital Medical Journal

Of nine patients with pericardial effusion due to various causes, four developed cardiac tamponade. Electrical alternans was present In all four, being total in three, and ventricular in one. From the diagnostic point of view, the alternans corresponded with the clinical diagnosis of cardiac tamponade and the radiological signs of a large pericardial effusion. The pericardial fluid was hemorrhagic in three patients and transudate (hydropericardium) in the fourth. In two patients alternans was present with heart rates below 100 per minute. Apart from the exact (1:1) type of electrical alternans, three new types are described; a 2:1, 3:1 and a …

Publications Of The Staff Of The Henry Ford Hospital And The Edsel B. Ford Institute For Medical Research

Henry Ford Hospital Medical Journal

No abstract provided.

Efficacy Of Betaprone With Ultraviolet Irradiation On Hepatitis B Antigen In Human Plasma Pools (A Retrospective Study), Gerald A. Logrippo, Hajime Hayashi

Henry Ford Hospital Medical Journal

In a retrospective study, hepatitis B antigen (HB Ag) was found in 14 lots of human plasma pools (16-20 liters each) that had been treated by the combined Betaprone (BPL) with ultraviolet (UV) irradiation procedure. No evidence of clinical hepatitis was found during a six-month follow-up after 185.2 liters of HB Ag positive plasma were Infused into 257 patients. Since HB Ag positive blood products treated by BPL with UV produced no clinical hepatitis, it is evident that our treatment is efficacious against hepatitis virus agents.

Blood Pressure In Hypertension, Lawrence H. Warbasse Jr.

Henry Ford Hospital Medical Journal

No abstract provided.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

A Study Of Water-Soluble Inhibitory Compounds (Algicides) Produced By Fresh-Water Algae, Denny O. Harris, Manhar C. Parekh

KWRRI Research Reports

A complex system of growth inhibitors was observed in the green algae (Volvocaceae). Inhibitors were found in the culture filtrates of some genera which limit their own growth (autoinhibitors) while others in the family produce substances which check the growth of other genera (heteroinhibitors). These inhibitors were destroyed by autoclaving. It was decided that Pandorina morum, which produced the strongest inhibitor and Volvox tertius, the most sensitive to the inhibitor would make an excellent model system for a study of the chemical and physical properties of these naturally occurring algicides. The algicide could be removed from actively growing cultures about …

Oral History Interview: Charles R. Knightstep, Charles R. Knightstep

0064: Marshall University Oral History Collection

Charles Knightstep was born in Jackson County, WV, but resided in Mason County WV, for the majority of his life. Mr. Knightstep reminiscences about his life growing up on a farm. He describes the process of drying fruits and vegetables and burying apples and potatoes for use during the winter. He explains how his grandmother and mother made lye soap, cottage cheese, and apple butter. He also describes courting his wife and visiting her by horse and buggy. Mr. Knightstep worked for the Kanawha and Michigan railroad beginning in 1915, when he was 15 years old. He describes the changes …

The Effects Of Atropine On The Growth And Respiration Of Two Species Of Bacteria Normally Inhabiting The Human Gastro-Intestinal System, Mary M. Ramos

Theses & Dissertations

It is the purpose of this study to determine whether the drug atropine has an effect on bacteria found normally inhabiting the human body, most specifically the gastrointestinal system. Atropine is one of the oldest drugs in medicine. It is derived from the roots and leaves of solanaceous plants such as henbane and Jimson weed. Atropine is often termed a belladonna alkaloid because it can also be found in the deadly nightshade plant, Atropa belladonna. Atropine is a highly competitive antagonist of acetylcholine at receptor sites in smooth muscles, cardiac muscle, and various glandular cells (5). Therefore, its effects are …

Ua77/1 Western Alumnus, Vol. 42, No. 6, Wku Alumni Association

WKU Archives Records

Alumni magazine published by WKU. This issue has the following articles:

• Wood, Willson. He Did Not Teach Art - He Taught People - Ivan Wilson
• Dixon, Frances. Russell Miller - Benevolent Despot of Western Theatre
• The Ivan Wilson Center for Fine Arts
• Conway, Sheila. For New Center . . . A Fine Arts Send-Off - Ivan Wilson Hall
• Hackney, Karen & Richard Hackney. Soaring in '77: Satellite Research
• Branham, Judy. Homecoming 1973
• Conway, Sheila. Music, By Gemini! - Gemini 15
• Given, Ed. For More Than A-Mews-ment - Marvin Mews
• Dunn, Thomas. WKU Professors Complete International TV Research
• Remember 1966-67
• Pomp, …

Localization Of Deep Abscesses With Radioactive Isotopes: An Experimental Study, H. M. Allen, R. Berguer, L. A. Dusault, M. A. Block

Henry Ford Hospital Medical Journal

Life-endangering effects of deep abscesses make early and precise identification and localization important to permit adequate surgical drainage. An experiment was undertaken to study the feasibility of detecting abscesses by using leucocytes tagged with radioactive isotopes. For the labeling, 51chromium appeared preferable to 131iodine or 99technetium. Leucocytes so labelled will concentrate sufficiently in abscesses to permit identification of abscesses by scintillation scanning. For clinical application, techniques require further simplification and refinement to eliminate interference by collection of radioactive isotopes in the liver and spleen.

A Clinical Trial Of Tobramycin With Pharmacological And Microbiological Studies, Keith Burch, Richard D. Nichols, Edward L. Quinn, Frank Cox, Evelyn J. Fisher, T. Madhavan, Donald Pohlod

Henry Ford Hospital Medical Journal

Tobramycin, a new aminoglycoside antibiotic, was shown to be effective in vitroagainst Pseudomonas, Klebsiella, Staphylococcus aureus, Enterobacter, Proteus mirabilis, indole-positive Proteus, and Eshcherichia coli. It was shown to produce serum and urine concentrations similar to gentamicin when administered intramuscularly. Preliminary animal studies showed this agent to have nephrotoxic and ototoxic effects similar to gentamicin. In our studies, tobramycin was well tolerated and produced only two transient elevations in serum creatinine and no abnormalities in audiograms and vestibular function tests. It was effective in 10 of 12 susceptible infections, including 2 of 4 with Pseudomonas endocarditis. Tobramycin compared favorably with gentamicin …

Haversian And Endosteal Bone Formation Rates In Rib Biopsies Of 50 Patients With Senile And Postmenopausal Osteoporosis, Kent K. Wu

Henry Ford Hospital Medical Journal

Eleventh rib biopsies of 50 patients with senile and postmenopausal osteoporosis, studied by means of tetracycline bone labeling, revealed significant and similar although modest decreases In bone formation on the cortical-endosteal and haversian surfaces of the biopsies.

Statistics For Clinical Research, W. R. Mccrum

Henry Ford Hospital Medical Journal

The purpose of this paper is to make understandable the use of statistics in the field of medicine, and to introduce to the clinician some new methods of statistics for drawing some reasonable conclusions based on the meager data usually available. There is, after all, only one valid use of statistics: to enable oneself to make a personal decision based on the information available.

Publications Of The Staff Of The Henry Ford Hospital And The Edsel B. Ford Institute For Medical Research

Henry Ford Hospital Medical Journal

No abstract provided.

Frank J. Sladen 1882-1973, Enisse Chimes

Henry Ford Hospital Medical Journal

No abstract provided.

Primary Biliary Cirrhosis With Systemic Sclerosis, Pedro A. Diaz, Bernard M. Schuman

Henry Ford Hospital Medical Journal

Two patients with combinedbilian/ cirrhosis and scleroderma are described. Both patients also presented features of the CRST syndrome, namely Raynaud's phenomenon, and telangiectasiae. Nine previously reported cases are reviewed and the clinical data suggest that a common underlying immunologic basis may account for both clinical conditions.

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

An Historical Review Of Oil Spills Along The Maine Coast 1953-1973, Edward H. Shenton

Maine Collection

An Historical Review of Oil Spills Along the Maine Coast 1953-1973

by Edward H. Shenton

Prepared for The Maine State Planning Office, Coastal Planning Group and The Research Institute of the Gulf of Maine (TRIGOM), August, 1973.

TRIGOM Publication No. 3

Contents: Introduction / A Chronology of Significant Oil Spills / A Summary of Biological Impacts / Spill Statistics / Discussion of Results / Conclusions of the Study / Recommendations for Future Research / Appendices

Effects Of A Nuclear Detonation On Arthropods At The Nevada Test Site, Dorald M. Allred

Brigham Young University Science Bulletin, Biological Series

Fifty-three arthropod species were studied in an area affected by an underground nuclear detonation. These were represented by 10 species of ants, 17 beetles, 5 orthopterans, 4 scorpions, 6 solpugids, and 11 spiders (Table 16). Relative populations were determined prior to the detonation and at three periods after the detonation–(1) one and two months after (August and September 1962), (2) 11 months after (June 1963), and (3) 13 months after (August 1963). One and two months after the detonation, the number of species was reduced from the expected by 48 percent, by 52 percent after 11 months, and by 66 …

Front Matter, Vol. 18 No. 4

Brigham Young University Science Bulletin, Biological Series

No abstract provided.

End Matter, Vol. 18 No. 4

Brigham Young University Science Bulletin, Biological Series

No abstract provided.

Phytoplankton Succession In The Lafayette River, Estuary, Norfolk, Virginia, Thomas W. Purcell Lll

Biological Sciences Theses & Dissertations

Abstract unavailable.

Experimentation To Develop Procedures To Be Used In The Investigation Of The Effects Of Restriction On The Unmodified Dna Of The Bacteriophage Lamda, John Haynes

Honors Theses

The results of experimentation approximately twenty years ago with variuos bacteriophages by Ralston and Krueger¹⁶, Anderson and Felix¹, Luria and Human¹², and by Bertani and Weigle² have shown that the host range of a given phage depends directly on the bacterial strain on which the phage has last propagated. This event came to be known as host-induced modification or host-controlled variation. As this phage host range is controlled by the host environment and can be altered from one generation to another it has, according to Luria, made microbiology "the last stronghold of Lamarckism" …

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

The Involvement Of Urinary Kallikrein In The Renal Escape From The Sodium Retaining Effect Of Mineralocorticoids, M. Marin-Grez, N. B. Oza, Oscar A. Carretero

Henry Ford Hospital Medical Journal

It is well known that the normal kidney "escapes" the sodium retaining effect of mineralocorticoids. However, the mechanism that mediates this "escape" is not understood. The possible role of kallikrein in this "escape" phenomenon was investigated by placing seven dogs in metabolic cages and giving them a constant sodium diet. After they had been on this diet three days, urine was collected for two 24-hour periods. DOCA (25 mg/day) was then given intramuscularly for five days. Urine was collected daily during this DOCA period and for two additional 24- hour periods. Urine volume, sodium, potassium, protein, and kallikrein excretion were …

The Scanning Electron Microscope: Applications At The Edsel B. Ford Institute For Medical Research, John H. L. Watson

Henry Ford Hospital Medical Journal

The Henry Ford Hospital with its research partner, The Edsel B. Ford Institute for Medical Research, was the first private medical center in the State of Michigan to purchase a scanning electron microscope and to begin to apply it, a year ago, to the study of medical and biological problems in both the animal and the human. This article briefly describes how the instrument works and shows some samples of micrographs produced.