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Total Nutrient Admixtures (3-In-1): Pros Vs Cons For Adults, Jane Gervasio Jul 2016

Total Nutrient Admixtures (3-In-1): Pros Vs Cons For Adults, Jane Gervasio

Jane M. Gervasio

Total nutrient admixture (TNA) is a complete parenteral nutrition (PN) formulation composed of all macronutrients, including dextrose, amino acids, and intravenous fat emulsions (IVFE), in one bag. The TNA may be safely administered to the patient, with all components aseptically compounded and minimal administration manipulation required, lending itself to decreases in risks of catheter contamination and patient infections. The TNA is compatible and stable at recommended concentrations, and since the IVFE is in the TNA, it is infused at slower rates, allowing for better fat clearance. The TNA offers convenience of administration and a potential cost savings to the healthcare …


Promoting Interprofessional Education Through A Student Led Community Health Screening Event, Carrie Maffeo, Eileen Carroll, Alexandra Foster, Kelly Daneri, Isabel Hagedorn, Mary Graham, Jane Gervasio Jul 2016

Promoting Interprofessional Education Through A Student Led Community Health Screening Event, Carrie Maffeo, Eileen Carroll, Alexandra Foster, Kelly Daneri, Isabel Hagedorn, Mary Graham, Jane Gervasio

Jane M. Gervasio

Published abstract from the 115th Annual Meeting of the American Association of Colleges of Pharmacy, Grapevine, TX, July 26-30.


Comment On Small Bowel Necrosis, Jane Gervasio Jul 2016

Comment On Small Bowel Necrosis, Jane Gervasio

Jane M. Gervasio

Comment on the Article Small bowel necrosis associated with postoperative jejunal tube feeding.


A.S.P.E.N. Parenteral Nutrition Safety Consensus Recommendations: Translation Into Practice, Phil Ayers, Stephen Adams, Joseph Boullata, Jane Gervasio, Beverly Holcomb, Michael D. Kraft, Neil Marshall, Antoinette Neal, Gordon Sacks, David S. Seres, Patricia Worthington, Peggi Guenter Jul 2016

A.S.P.E.N. Parenteral Nutrition Safety Consensus Recommendations: Translation Into Practice, Phil Ayers, Stephen Adams, Joseph Boullata, Jane Gervasio, Beverly Holcomb, Michael D. Kraft, Neil Marshall, Antoinette Neal, Gordon Sacks, David S. Seres, Patricia Worthington, Peggi Guenter

Jane M. Gervasio

Parenteral nutrition (PN) serves as an important therapeutic modality that is used in adults, children, and infants for a variety of indications. The appropriate use of this complex therapy aims to maximize clinical benefit while minimizing the potential risk for adverse events. Despite being classified and acknowledged as a high-alert medication,1 only 58% of organizations have precautions in place to prevent errors and patient harm associated with PN.2 Complications can occur as a result of the therapy and as the result of the PN process. The American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.) Parenteral Nutrition Safety Consensus Recommendations are …


Standardized Competencies For Parenteral Nutrition Prescribing: The American Society For Parenteral And Enteral Nutrition Model, Peggi Guenter, Joseph I. Boullata, Phil Ayers, Jane Gervasio, Ainsley Malone, Erica Raymond, Beverly Holcombe, Michael Kraft, Gordon Sacks, David Seres Jul 2016

Standardized Competencies For Parenteral Nutrition Prescribing: The American Society For Parenteral And Enteral Nutrition Model, Peggi Guenter, Joseph I. Boullata, Phil Ayers, Jane Gervasio, Ainsley Malone, Erica Raymond, Beverly Holcombe, Michael Kraft, Gordon Sacks, David Seres

Jane M. Gervasio

Parenteral nutrition (PN) provision is complex, as it is a high-alert medication and prone to a variety of potential errors. With changes in clinical practice models and recent federal rulings, the number of PN prescribers may be increasing. Safe prescribing of this therapy requires that competency for prescribers from all disciplines be demonstrated using a standardized process. A standardized model for PN prescribing competency is proposed based on a competency framework, the American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.)–published interdisciplinary core competencies, safe practice recommendations, and clinical guidelines. This framework will guide institutions and agencies in developing and maintaining …


Renal Phosphorus Regulation In Thermally-Injured And Multiple Trauma Patients Receiving Enteral Nutrition, Jane M. Gervasio, Rex O. Brown, Justin J. Sherman, William L. Hickerson, Kenneth A. Kudsk, Roland N. Dickerson May 2014

Renal Phosphorus Regulation In Thermally-Injured And Multiple Trauma Patients Receiving Enteral Nutrition, Jane M. Gervasio, Rex O. Brown, Justin J. Sherman, William L. Hickerson, Kenneth A. Kudsk, Roland N. Dickerson

Jane M. Gervasio

Abstract from the 22nd Clinical Congress of the American Society for Parenteral and Enteral Nutrition, Orlando, FL, January 18-21, 1998.


Measured Energy Expenditure Of Nonambulatory Patients With Severe Neurodevelopmental Disabilities, Roland Dickerson, Rex Brown, Jane Gervasio, Emily Hak, John Williams, Lawrence Hak May 2014

Measured Energy Expenditure Of Nonambulatory Patients With Severe Neurodevelopmental Disabilities, Roland Dickerson, Rex Brown, Jane Gervasio, Emily Hak, John Williams, Lawrence Hak

Jane M. Gervasio

Abstract from American College of Clinical Pharmacy 1997 Annual Meeting, Phoenix, AZ, November 9-12, 1997.


Enteral Cisapride, Erythromycin, And Metoclopramide In Critically Ill Patients Intolerant To Enteral Nutrition: A Randomized, Placebocontrolled, Cross-Over Study, Robert Maclaren, Jane M. Gervasio, David A. Kuhl, Teresa N. Livingston, Kyle Swift, Roland N. Dickerson, Rex O. Brown, Stacey Headley, Kenneth A. Kudsk, John J. Lima May 2014

Enteral Cisapride, Erythromycin, And Metoclopramide In Critically Ill Patients Intolerant To Enteral Nutrition: A Randomized, Placebocontrolled, Cross-Over Study, Robert Maclaren, Jane M. Gervasio, David A. Kuhl, Teresa N. Livingston, Kyle Swift, Roland N. Dickerson, Rex O. Brown, Stacey Headley, Kenneth A. Kudsk, John J. Lima

Jane M. Gervasio

Abstract from American College of Clinical Pharmacy 1997 Annual Meeting, Phoenix, AZ, November 9-12, 1997.


Comparison Of Arterial Plasma Amino Acid Concentrations In Rats Fed Ad Lib Oral Chow Or Parenteral Nutrition Via Intravenous Or Gastric Infusion, Jane M. Gervasio, Emily B. Hak, Michael C. Storm, M. E. Croft, Lawrence J. Hak May 2014

Comparison Of Arterial Plasma Amino Acid Concentrations In Rats Fed Ad Lib Oral Chow Or Parenteral Nutrition Via Intravenous Or Gastric Infusion, Jane M. Gervasio, Emily B. Hak, Michael C. Storm, M. E. Croft, Lawrence J. Hak

Jane M. Gervasio

Abstract from the 22nd Clinical Congress of the American Society for Parenteral and Enteral Nutrition, Orlando, FL, January 18-21, 1998.


Accuracy Of Predictive Formulas To Estimate Resting Energy Expenditure Of Thermally Injured Patients, Roland N. Dickerson, Jane M. Gervasio, Marti L. Riley, James E. Murrell, William L. Hickerson, Kenneth A. Kudsk, Rex O. Brown May 2014

Accuracy Of Predictive Formulas To Estimate Resting Energy Expenditure Of Thermally Injured Patients, Roland N. Dickerson, Jane M. Gervasio, Marti L. Riley, James E. Murrell, William L. Hickerson, Kenneth A. Kudsk, Rex O. Brown

Jane M. Gervasio

Abstract from the 25th Clinical Congress of the American Society for Parenteral and Enteral Nutrition, Chicago, IL, January 21-24, 2001.


Blood Glucose Concentration Does Not Correlate With Organ Failure Or Outcome In Trauma Patients Receiving Enteral Nutrition, Jennifer L. Ash, Jane M. Gervasio, Gary P. Zaloga, George H. Rodman Jr. May 2014

Blood Glucose Concentration Does Not Correlate With Organ Failure Or Outcome In Trauma Patients Receiving Enteral Nutrition, Jennifer L. Ash, Jane M. Gervasio, Gary P. Zaloga, George H. Rodman Jr.

Jane M. Gervasio

Abstract from American College of Clinical Pharmacy 2005 Spring Practice and Research Forum/Updates in Therapeutics, Myrtle Beach, SC, April 10-13, 2005.


Does The Quantity Of Enteral Nutrition Affect Outcomes In Critically Ill Trauma Patients?, Jennifer Ash, Jane Gervasio, Gary Zaloga, George Rodman Jr. May 2014

Does The Quantity Of Enteral Nutrition Affect Outcomes In Critically Ill Trauma Patients?, Jennifer Ash, Jane Gervasio, Gary Zaloga, George Rodman Jr.

Jane M. Gervasio

Abstract from Clinical Nutrition Week, Orlando, FL, January 29-February 2, 2005.


Enhanced Student Learning And Scholarly Productivity Through Capstone Projects, Bruce Hancock, Jane Gervasio, Iftekhar Kalsekar, Julie Koehler, Mary Andritz May 2014

Enhanced Student Learning And Scholarly Productivity Through Capstone Projects, Bruce Hancock, Jane Gervasio, Iftekhar Kalsekar, Julie Koehler, Mary Andritz

Jane M. Gervasio

Abstract from the American Association of Colleges of Pharmacy/Association of Faculties of Pharmacy of Canada Annual Meeting, Chicago, IL, July 16-24, 2008.


Expansion Of Experiential Learning Opportunities Through Medication Reconciliation Participation, Jane M. Gervasio, Julie M. Koehler, Kevin M. Tuohy, Julie L. Williams, Mary H. Andritz May 2014

Expansion Of Experiential Learning Opportunities Through Medication Reconciliation Participation, Jane M. Gervasio, Julie M. Koehler, Kevin M. Tuohy, Julie L. Williams, Mary H. Andritz

Jane M. Gervasio

Abstract from the American Association of Colleges of Pharmacy Annual Meeting, Orlando, FL, July 12-18, 2007.


Nutritional Support In The Acute Care Patient Post-Ventricular Assist Device Placement, Abby Re, Jane M. Gervasio, Robert D. Warhurst, Gary P. Zaloga May 2014

Nutritional Support In The Acute Care Patient Post-Ventricular Assist Device Placement, Abby Re, Jane M. Gervasio, Robert D. Warhurst, Gary P. Zaloga

Jane M. Gervasio

Abstract from American College of Clinical Pharmacy Annual Meeting, San Francisco, CA, October 23-26, 2005.


Bowel Necrosis Associated With Enteral Feeding, Jane M. Gervasio, Ryan Ednalino, Jennifer Reynolds, Gary P. Zaloga May 2014

Bowel Necrosis Associated With Enteral Feeding, Jane M. Gervasio, Ryan Ednalino, Jennifer Reynolds, Gary P. Zaloga

Jane M. Gervasio

Abstract from Clinical Nutrition Week, Dallas, TX, February 12-15, 2006.


Enhanced Student Learning And Public Health Awareness Through Capstone Projects, Jane Gervasio, Carriann Richey, Bruce Hancock, Iftekhar Kalsekar, Julie Koehler, Mary Andritz May 2014

Enhanced Student Learning And Public Health Awareness Through Capstone Projects, Jane Gervasio, Carriann Richey, Bruce Hancock, Iftekhar Kalsekar, Julie Koehler, Mary Andritz

Jane M. Gervasio

Abstract from the 110th Annual Meeting of the American Association of Colleges of Pharmacy, Boston, MA, July 18-22, 2009.


A Comparison Of Efficacy Of Heparin 0.5 Unit/Ml Versus Heparin 1 Unit/Ml In Parenteral Nutrition Administrated In The Neonatal Population, Jane M. Gervasio, Meredith Mckinney, Iftekar Kalsekar, Elaina Szeszycki May 2014

A Comparison Of Efficacy Of Heparin 0.5 Unit/Ml Versus Heparin 1 Unit/Ml In Parenteral Nutrition Administrated In The Neonatal Population, Jane M. Gervasio, Meredith Mckinney, Iftekar Kalsekar, Elaina Szeszycki

Jane M. Gervasio

Abstract from Clinical Nutrition Week, Las Vegas, NV, February 8-10, 2010.


Evaluation Of Enteral Feeding Success In Head Injured Patients Placed In Pentobarbital Induced Comas, Jane M. Gervasio, Jonathan Egel, Joshua Mcgehee, Gabriel Drew Stillabower, Nicole Ponton, Lawrence Bortenschlager, Timothy Pohlman May 2014

Evaluation Of Enteral Feeding Success In Head Injured Patients Placed In Pentobarbital Induced Comas, Jane M. Gervasio, Jonathan Egel, Joshua Mcgehee, Gabriel Drew Stillabower, Nicole Ponton, Lawrence Bortenschlager, Timothy Pohlman

Jane M. Gervasio

Abstract of Distinction from Clinical Nutrition Week, Las Vegas, NV, February 8-10, 2010.


Teaching Residents To Teach: Preparing Faculty And Clinical Educators, Sarah Nisly, Tracy Sprunger, Alison Walton, Tracy Costello, Jane M. Gervasio, Mary H. Andritz May 2014

Teaching Residents To Teach: Preparing Faculty And Clinical Educators, Sarah Nisly, Tracy Sprunger, Alison Walton, Tracy Costello, Jane M. Gervasio, Mary H. Andritz

Jane M. Gervasio

Abstract from the 114th Annual Meeting of the American Association of Colleges of Pharmacy, Chicago, IL, July 13-17, 2013.


Chronic Hypothermia And Energy Expenditure In A Neurodevelopmentally Disabled Patient: A Case Study, Jane Gervasio, Roland Dickerson, Rex Brown, J. Matthews May 2014

Chronic Hypothermia And Energy Expenditure In A Neurodevelopmentally Disabled Patient: A Case Study, Jane Gervasio, Roland Dickerson, Rex Brown, J. Matthews

Jane M. Gervasio

Hypothermia is defined as a core body temperature of <35°C and results in a decrease in measured resting energy expenditure. A 51-year-old mentally disabled patient experienced chronic hypothermia from neurologic sequelae. Because of her continued weight gain and increased body fat in the presence of presumed hypocaloric nutrition, indirect calorimetry measurements were performed twice in a 3-month period. The resting energy expenditure measurements prompted a reduction of her daily caloric intake to prevent further overfeeding. Hypothermia reduces oxygen consumption and, as a consequence, decreases resting energy expenditure. In patients for whom chronic hypothermia is a problem, nutritional intake must be …


Sequential Group Trial To Determine Gastrointestinal Site Of Absorption And Systemic Exposure Of Azathioprine, Jane M. Gervasio, Rex O. Brown, John Lima, M. G. Tabbaa, Thomas Abell, Robert Werkman, Lynda J. Haberer, Lawrence J. Hak May 2014

Sequential Group Trial To Determine Gastrointestinal Site Of Absorption And Systemic Exposure Of Azathioprine, Jane M. Gervasio, Rex O. Brown, John Lima, M. G. Tabbaa, Thomas Abell, Robert Werkman, Lynda J. Haberer, Lawrence J. Hak

Jane M. Gervasio

Azathioprine (AZA) is used in the treatment of patients with refractory inflammatory bowel disease; however, its use is limited because of systemic toxicity associated with long-term use. Ileocecal delivery of AZA might be advantageous if local intestinal therapeutic effects could be provided with decreased systemic side effects. Decreased cecal systemic absorption would allow higher dosages of AZA to be administered. A two-phase study was performed to compare the systemic exposure of AZA and 6-mercaptopurine (6-MP) following administration of AZA into the stomach, jejunum, and cecum and to compare the systemic exposure to AZA and 6-MP following administration of three different …


Sequential Single Doses Of Cisapride, Erythromycin, And Metoclopramide In Critically Ill Patients Intolerant To Enteral Nutrition: A Randomized, Placebo-Controlled, Crossover Study, Robert Maclaren, David A. Kuhl, Jane M. Gervasio, Rex O. Brown, Roland N. Dickerson, Teresa N. Livingston, Kyle Swift, Stacey Headley, Kenneth A. Kudsk, John J. Lima May 2014

Sequential Single Doses Of Cisapride, Erythromycin, And Metoclopramide In Critically Ill Patients Intolerant To Enteral Nutrition: A Randomized, Placebo-Controlled, Crossover Study, Robert Maclaren, David A. Kuhl, Jane M. Gervasio, Rex O. Brown, Roland N. Dickerson, Teresa N. Livingston, Kyle Swift, Stacey Headley, Kenneth A. Kudsk, John J. Lima

Jane M. Gervasio

Objective: To evaluate the comparative efficacy of enteral cisapride, metoclopramide, erythromycin, and placebo for promoting gastric emptying in critically ill patients with intolerance to gastric enteral nutrition (EN). Design: A randomized, crossover study. Setting: Adult medical intensive care unit at a university-affiliated private hospital and trauma intensive care unit at a university teaching hospital. Patients: Ten adult, critically ill, mechanically ventilated patients not tolerating a fiber-containing EN product defined as a single aspirated gastric residual volume >150 mL or two aspirated gastric residual volumes >120 mL during a 12-hr period. Interventions: Patients received 10 mg of cisapride, 200 mg of …


Measured Energy Expenditure Of Tube-Fed Patients With Severe Neurodevelopment Disabilities, Roland N. Dickerson, Rex O. Brown, Jane M. Gervasio, Emily B. Hak, Lawrence J. Hak, John E. Williams May 2014

Measured Energy Expenditure Of Tube-Fed Patients With Severe Neurodevelopment Disabilities, Roland N. Dickerson, Rex O. Brown, Jane M. Gervasio, Emily B. Hak, Lawrence J. Hak, John E. Williams

Jane M. Gervasio

Objective: To determine measured resting energy expenditure (REE) of nonambulatory tube-fed patients with severe neurological neurodevelopmental disabilities. Methods: Twenty patients were prospectively studied. Only steady state indirect calorimetry measurements were taken. All measurements were conducted using a canopy system. Nutritional needs were met entirely by enteral feedings via a permanent ostomy. Results: REE was widely distributed from 16 kcals/kg/day to 39 kcals/kg/day. The mean REE (888 ±176 kcals/day) of the patients was significantly (p < 0.01) lower than predicted as estimated by the Harris-Benedict equations (1081 ± 155 kcals/day) and World Health Organization equations (1194 ± 167 kcals/day). Fat-free mass (FFM) …


Oxandrolone In Trauma Patients, Jane M. Gervasio, Roland N. Dickerson, Jessica Swearingen, Mary E.D. Yates, Ceaminia Yuen, Timothy C. Fabian, Martin A. Croce, Rex O. Brown May 2014

Oxandrolone In Trauma Patients, Jane M. Gervasio, Roland N. Dickerson, Jessica Swearingen, Mary E.D. Yates, Ceaminia Yuen, Timothy C. Fabian, Martin A. Croce, Rex O. Brown

Jane M. Gervasio

Study Objective To determine the effect of oxandrolone administration on nutritional and clinical outcomes after multiple trauma. Design Prospective, randomized, double-blind, placebo-controlled study. Setting. Level 1 trauma center in a university teaching hospital. Patients Sixty-two patients requiring enteral nutrition, 60 of whom completed the study. Intervention Patients were randomized to receive either oxandrolone 10 mg or placebo twice/day for a maximum of 28 days. Measurements and Main Results Total urinary nitrogen, prealbumin, nitrogen balance, total body water, and body cell mass were measured on day 1 of enteral nutrition and then at day 7, day 10, and study exit. Patients …


A Comparison Of Renal Phosphorus Regulation In Thermally-Injured And Multiple Trauma Patients Receiving Specialized Nutrition Support, Roland N. Dickerson, Jane M. Gervasio, Justin J. Sherman, Kenneth A. Kudsk, William L. Hickerson, Rex O. Brown May 2014

A Comparison Of Renal Phosphorus Regulation In Thermally-Injured And Multiple Trauma Patients Receiving Specialized Nutrition Support, Roland N. Dickerson, Jane M. Gervasio, Justin J. Sherman, Kenneth A. Kudsk, William L. Hickerson, Rex O. Brown

Jane M. Gervasio

To compare phosphorus intake and renal phosphorus regulation between thermally injured patients and multiple trauma patients, 40 consecutive critically ill patients, 20 with thermal injury and 20 with multiple trauma, who required enteral tube feeding were evaluated. Phosphorus intakes were recorded for 14 days from the initiation of tube feeding which was started 1 to 3 days post-injury. Serum for determination of phosphorus concentrations was collected at days 1, 3, 7, and 14 of the study period. A 24-hour urine collection was obtained during the first and second weeks of nutrition support for urinary phosphorus excretion, fractional excretion of phosphorus, …


Accuracy Of Predictive Methods To Estimate Resting Energy Expenditure Of Thermally-Injured Patients, Roland N. Dickerson, Jane M. Gervasio, Marti L. Riley, James E. Murrell, William L. Hickerson, Kenneth A. Kudsk, Rex O. Brown May 2014

Accuracy Of Predictive Methods To Estimate Resting Energy Expenditure Of Thermally-Injured Patients, Roland N. Dickerson, Jane M. Gervasio, Marti L. Riley, James E. Murrell, William L. Hickerson, Kenneth A. Kudsk, Rex O. Brown

Jane M. Gervasio

Background The purpose of this study was to evaluate the bias and precision of 46 methods published from 1953 to 2000 for estimating resting energy expenditure (REE) of thermally injured patients. Methods Twenty-four adult patients with ≥20% body surface area burn admitted to a burn center who required specialized nutrition support and who had their REE measured via indirect calorimetry (IC) were evaluated. Patients with morbid obesity, human immunovirus, malignancy, pregnancy, hepatic or renal failure, neuromuscular paralysis, or those requiring a FiO2 >50% or positive end expiratory pressure (PEEP) ≥10 cm H2O were excluded. One steady-state measured REE measurement (MEE) …


Nutrition In The Critically Ill Patient, Jane M. Gervasio May 2014

Nutrition In The Critically Ill Patient, Jane M. Gervasio

Jane M. Gervasio

Critical illness presents with the classic response to stress, including hypermetabolism and increased catabolism, resulting in a negative energy and nitrogen balance. These harmful events initiate the immunological response, starting with the systemic inflammatory response syndrome, which, if not resolved, may lead to multiple organ dysfunction syndrome (MODS). Furthermore, patients who do not develop early MODS manifest a compensation anti-inflammatory response syndrome, which suppresses immunity and predisposes the patient to sepsis, thereby ­increasing the risk of late MODS and ultimately death. The use of specialized nutrition support, including enteral nutrition (EN) and parenteral nutrition (PN), has been initiated in an …


Anabolic Agents: Adjuncts To Nutrition Support, Jane Gervasio May 2014

Anabolic Agents: Adjuncts To Nutrition Support, Jane Gervasio

Jane M. Gervasio

Anabolic agents as adjuncts to nutrition support therapy have been used to improve malnutrition and establish anabolism. Growth hormone, insulin-like growth factor, and anabolic steroids have been studied for their potential to reverse the catabolic process and promote anabolism. This paper reviews several anabolic agents and their possible role in nutrition support therapy.


2005 American Society For Parenteral And Enteral Nutrition (A.S.P.E.N.) Standards And Guidelines Survey, David Seres, Charlene Compher, Douglas Seidner, Laura Byham-Gray, Jane M. Gervasio, Stephen Mcclave May 2014

2005 American Society For Parenteral And Enteral Nutrition (A.S.P.E.N.) Standards And Guidelines Survey, David Seres, Charlene Compher, Douglas Seidner, Laura Byham-Gray, Jane M. Gervasio, Stephen Mcclave

Jane M. Gervasio

An online survey about the use and format of the American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.) Standards and Guidelines documents was conducted. The survey was sent to A.S.P.E.N. members, and an acceptable number of responses were received (470, or 9% of those surveyed). Most respondents indicated an overall satisfaction with the standards and guidelines and suggested format changes, many of which will be incorporated into future guidelines and standards. The results of this survey are presented here for general interest. Changes in the process with which A.S.P.E.N. produces standards and guidelines are discussed.