Medicine and Health Sciences Commons^™

Development Of A Semi-Quantitative Methodology For Evaluation Of Whole-Body Chemical, Biological, Radiological, And Nuclear Decontamination Using An Ultraviolet Fluorescent Aerosol, Emily M. Titus

Theses and Dissertations

This work describes a literature review which was conducted on publicly available literature on chemical, biological, radiological, and nuclear (CBRN) decontamination to understand the body of knowledge and gaps in this body of knowledge, including the assumption that disrobing after a CBRN incident will remove 90% of contamination. Also included is a description of the design and characterization of an aerosol test chamber which was constructed for use in this research. Finally, the bulk of this work describes the development of a semi-quantitative methodology for visualizing contamination. This method uses an ultraviolet fluorescent aerosol (to simulate contamination by a chemical …

Survey Of Airflow Around A Heated Manikin As A Simulated Aeromedical Evacuation Patient On A Litter With Computational Fluid Dynamics Models, George P. Lemmer

Theses and Dissertations

Aeromedical Evacuations remain the predominant method used to transport patients from forward deployed areas of operations to secure locations with more robust medical infrastructure. Transportation of chemical warfare casualties and infectious patients require additional attention to prevent cross contamination. Specific airflow characteristics paired with environmental control system settings are a gap in scholarly literature. Based on the available literature computational fluid dynamics models were created to simulate the airflow around a patient represented by human geometry using commercially available software. In order to compare simulated and experimental results a heated manikin was placed in the MURPHEE aerosol exposure chamber and …

Development And Characterization Of A Filter-Based Bioaerosol Sampler Capable Of Integration Into Small Unmanned Aerial Systems, Stephanie A. Ohms

Theses and Dissertations

In developing functional SUAS, performance characteristics that indicate system capability should be developed prior to initiating initial system design. Key performance parameters should be developed involving all system elements (including vehicle body, operator, ground station, sensor, and algorithm or processing module). A bioaerosol sampler designed specifically for the use in SUAS was characterized based on designated performance measures to determine overall effectiveness compared to traditional bioaerosol samplers. For a system with a goal of accurately identifying and quantifying areas of airborne biological contamination or surveying background levels for longitudinal studies, performance parameters such as weight of the vehicle with payload …

Retrospective Cohort Study Of Pure Tone Audiometry Threshold Shifts From Ototoxic Substance, Continuous Noise, And Impulse Noise Exposures At Tinker Air Force Base From 2005 To 2019, Marc J. Blair

Theses and Dissertations

This retrospective cohort epidemiology study sought to establish the comparative risks and potential indicators of hearing loss associated with combinations of ototoxic substances, impulse noise, and continuous noise exposure. Currently, there is not an existing model or methodology in the Department of Defense (DoD) that joins occupational exposure data and pure tone audiometric data. After developing an integrated database model for Tinker Air Force Base, the largest of three depot installations within Air Force Material Command, 2,372 individuals were grouped into eight combinations of exposure groups with a minimum three years exposure duration to hazards. The incidence rates and relative …

Assessing Challenges Associated With Sampling Hexavalent Chromium Under New Consensus Guidelilnes, Megan L. Steele

Theses and Dissertations

Hexavalent chromium is a corrosion inhibitor found in the primer of most aircraft platforms across the Department of Defense (DoD), from fighter jets to transports. It is also known to cause cancer in humans. Currently, the Occupational Safety and Health Administration (OSHA) legal exposure limit is 5 μg/m³ for workers exposed to hexavalent chromium. A non-regulatory scientific body has recently recommended lowering this exposure level over a factor of ten and sampling with a different sampler that collects particles with the same efficiency as the nose during inhalation. This inhalable sampler collects more particles than the one currently used …

Electronic Image Detectability Under Varying Illumination Conditions, Jeremy J. Miller

Theses and Dissertations

Light in the built environment plays an essential role in the vision and the health of humans through non-visual receptors in the eyes. Unfortunately, image analysts and other Air Force personnel who engage in the detection of objects on softcopy displays are often required to work in very dimly-lit or dark environments as higher illumination reduces the contrast of displayed information. Literature has shown that increases in light exposure improves circadian rhythm entrainment and reduces the negative health consequences of insufficient lighting. This research examines the effects of indoor lighting to determine if increases in ambient illumination or changes to …

Radiological Decontamination In The Urban Environment Utilizing An Irreversible Wash-Aid Recovery System, Keith A. Sanders

Theses and Dissertations

The radioactive fallout from the Fukushima Daiichi nuclear reactors accident and the ongoing threat of nuclear or radioactive terrorism have forced the need for urban radiological decontamination into the forefront. Many of the established decontamination techniques are not ideally suited for the urban milieu. One of the keys to maximize the effectiveness of long-term remediation and recovery in the urban environment is immediate mitigation within a few days of the incident and before a rain event. The Integrated Wash-Aid, Treatment, and Emergency Reuse System (IWATERS) provides a potentially safe and effective method for early responders and remediation teams to perform …

Occupational Noise Dose Reduction Via Behavior Modification Using In-Ear Dosimetry Among Usaf Personnel Exposed To Continuous Impulse Noise, Jesse A. Trawick

Theses and Dissertations

The purpose of this research was to investigate the use of in-ear noise dosimetry and worker feedback to reduce noise exposures among combat arms instructors and heavy equipment operators in the Air Force. Specifically, this thesis sought to determine how effectively hearing protection devices (HPDs) are being utilized currently, and whether providing at-ear noise exposure data to workers results in reduced noise exposures or changes in worker attitude. These questions were addressed by performing a six-month field study using dosimeters to record worker noise exposures under HPDs. Subjects served as their own control, receiving feedback in only the latter half …

Characterization Of Jet Fuel Combustion Emissions During A C-130 Aeromedical Evacuation Engines Running Onload, Michelle L. Page

Theses and Dissertations

The purpose of this research was to characterize jet fuel combustion emissions (JFCE) in an occupational setting. Prior research demonstrated that aircraft emit hazardous species, especially at engine start-up and ground idle. Complaints of eye, nose, and throat irritation from occupational exposures near aircraft exist. In this study JFCE were tested during an aeromedical evacuation engines running patient onload (ERO) on a C-130 Hercules at the 179^th Airlift Wing, Mansfield-Lahm Air National Guard. Ultrafine particles, VOC, formaldehyde, carbon monoxide (CO), sulfuric acid, and metals were sampled simultaneously in approximate crew and patient breathing zones. Testing methods were portable condensation …

Optimal Configurations For Aerosol Monitoring With Multi-Rotor Small Unmanned Aerial Systems, Inna D. Chavez

Theses and Dissertations

Applicability of aerosol sampling on multi-rotor unmanned aerial systems (UAS) platform was investigated. Multi-rotor UAS have impacts of wind speed, turbulence, and orientation possibly contributing to sampling bias. The SKC IMPACT sampler, Tecora C.A.Th.I.A., and modified three-dimensionally printed Universal Inlet for Airborne-Particle Size-Selective Sampling were selected based on particle size-selectivity and operational independence to wind. Airflow visualizations concluded that below UAS fuselage was optimal sampler placement. Tests were conducted with Arizona Road Dust in a still-air chamber, and aerosolized sugar in a wind tunnel. Inlet mounting was evaluated in, upright, upside-down, and horizontal orientations. Horizontal orientations of all inlets resulted …

Internet-Based Behavior Of It Professionals: Implications For Online Ergonomic Education To Prevent Work-Related Musculoskeletal Disorders, Priyadarshini Pattath

Theses and Dissertations

INTERNET-BASED BEHAVIOR OF IT PROFESSIONALS: IMPLICATIONS FOR ONLINE ERGONOMIC EDUCATION TO PREVENT WORK-RELATED MUSCULOSKELETAL DISORDERS

By Priyadarshini Pattath, Ph.D. A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Virginia Commonwealth University Virginia Commonwealth University, 2017 Director: Dr. Robin Hurst, Assistant Professor of Adult Learning, Teaching and Learning,

School of Education

The purpose of this study was to explore the preferences of medium of ergonomic education and views about self-directed online training modules to prevent musculoskeletal disorders in computer professionals and understand their perspectives and experiences about online health information seeking using a …

Neck Injury Criteria Development For Use In System Level Ejection Testing; Characterization Of Atd To Human Response Correlation Under -Gx Accelerative Input, Craig M. Zinck

Theses and Dissertations

The use of Helmet Mounted Displays is ubiquitous in the field of aviation, adding operational capability, increasing head-supported weight and potential neck injury risk. Developing neck injury criteria to evaluate and quantify neck injury is important to ensure ejection systems are produced within acceptable standards. An ATD to human transfer function is developed that quantifies the difference between ATD and human neck response from -Gx accelerative tests, and demonstrates how this function can be applied to ATD test data to make previously developed human risk functions directly applicable to interpreting ATD data with a human based neck injury criterion. A …

Using Artificial Neural Networks To Predict Disease Associations For Chemicals Present In Burn Pit Emissions, Amanda R. Taylor

Theses and Dissertations

In June of 2015, 27,378 of the 28,000 returning Operation Iraqi Freedom/Operation Enduring Freedom (OIF/OEF) veterans report being exposed to burn pits. According to Barth et al. (2014), 9,660 returning OIF/OEF veterans were diagnosed with respiratory diseases, to include asthma, bronchitis, and sinusitis, thus strengthening the need to develop decision support tools that can be used to understand the relationships between chemical exposure and disease. In this study an Artificial Neural Network (ANN) was used to predict the chemical-disease associations for burn pit constituents. Ten burn pit constituents were tested using varying hidden layers, similar chemical structure relationships, and three …

Field Evaluation Of Solvent-Free Sampling With Di-N-Butylamine For The Determination Of Airborne Monomeric And Oligomeric 1,6-Hexamethylene Diisocyanate, Tiffany R. Heline

Theses and Dissertations

During this study, a field evaluation of a new sampling method using di-n-butylamine for the determination of airborne monomeric and oligomeric 1,6-hexamethylene diisocyanate (HDI) was performed. The Supelco ASSET EZ4-NCO Dry Sampler was compared to the Omega Specialty Instrument Co. ISO-CHEK sampler. Three specific questions were addressed: 1) can HDI oligomers be quantified using HPLC-MS; 2) do ASSET and ISO-CHEK samplers collect equivalent HDI monomer & oligomer concentrations; and 3) what is the relative cost of ASSET samplers verse ISO-CHEK. Side-by-side HDI air sampling was conducted during polyurethane spray painting operations. ASSET samplers were analyzed by HPLC-MS for HDI monomer …

Dr. Who?: The Science And Culture Of Medical Wear Design, Patricia Duignan

Theses and Dissertations

The multi-million-dollar medical uniform industry has not utilized advancements in garment and textile technology that could positively impact the protection of healthcare professionals and patients. In most cases the uniforms meet basic requirements – they clothe the professional in a recognizable way. Little innovation in design, function and performance, has been applied to these garments. This is particularly evident in the case of the stereotypical white lab coat worn by many physicians, despite evidence indicating that these lab coats may carry contamination and play a role in the spread of deadly bacteria. Healthcare Associated Infections (HAIs) are among the most …

Trends In Work-Related Injury Rates And The Associated Incurred Costs In Long-Term Care Centers, Darcie Lange Olson

Theses and Dissertations

Background. Nursing assistants, working in long-term care facilities, have consistently been among the top occupational groups experiencing work-related musculoskeletal injuries. These injuries have been attributed the physical demands of lifting and moving the individuals in their care. Great strides in research have identified successful risk reduction strategies such as the implementation safe patient handling and mobility programs. The benefits of these programs have been advocated over the last two decades, but the rate of injuries among nursing assistants continues to be more than double the national average for all other industries. The purpose of this study was to investigate the …

Feasibility And Preliminary Outcomes From A Pilot Study Of The Smile Curriculum For Mother-Infant Co-Occupational Engagement And Maternal Self-Efficacy, Emily Whitlock

Theses and Dissertations

OBJECTIVE: To report on the feasibility and preliminary outcomes from a pilot study of the SMILE curriculum, a new educational program designed to enhance the mother-infant relationship by focusing on improvement of co-occupational engagement within daily routines.

METHOD: Six mothers, each with an infant diagnosed with special medical needs who received services in a local birth-to-three program, participated in an exploratory design study. Each mother was assigned to a SMILE curriculum intervention group or a waiting-list control group. Mothers were evaluated pre- and post-intervention using the Perceived Maternal Parenting Self-Efficacy (PMP-SE) Scale for measurement of maternal self-efficacy and the Center …

Health Risk Assessments Of Waste Combustion Emissions Using Surrogate Analyte Models, Michael A . Schmidt

Theses and Dissertations

Exposure assessments of open burn pits are often complicated by a lack of sampling equipment and resources. This research investigated the hypothesis of carbon dioxide (CO₂) as a viable surrogate for particulate matter with diameter ≤ 2.5 μm (PM2.5). Large-scale solid waste combustion tests resulted in linear trends between mean PM2.5 and CO₂ (R2 = 0.964 - 0.989). This pilot study demonstrates the feasibility of using CO₂ as a surrogate of PM2.5 concentration as CO₂ sensors potentially provide a cost-effective solution for monitoring in lieu of expensive PM instruments. It also indicates the potential reduction …

Comparative Analysis Of Two Biological Warfare Air Samplers Using Live Surrogate Agents, James C. Enderby

Theses and Dissertations

The United States Air Force has several high-volume biological air samplers, including the XMX/2L-MIL and the Biocapture 650. Limited information is available on either in terms of its collection of viruses and bacteria. However, previous research on the XMX/2L-MIL has determined that modifications to the secondary flow rate and the use of a virus preserving collection media may provide improved virus collection rates. In this thesis, these modifications were investigated to determine their impact on the collection of viral and bacterial aerosols. Additionally, relative collection rates were compared against those for the Biocapture 650. MS2 bacteriophage was the viral surrogate …

Probabilistic Model For Laser Damage To The Human Retina, David R. Wooddell

Theses and Dissertations

Understanding how lasers interact with media during propagation is a premiere field of physics. The subject area known as laser bioeffects explores laser interactions with biological cells, tissues, organs, and bodies. This research includes laser applications used in medicine, establishes safe exposure limits for industry and academia, and generally studies the many effects of laser light on living creatures. The bioeffects community relies heavily on deterministic modeling and simulation tools to support experimental research into damage thresholds and laser effects. However, recent laser applications require a probabilistic approach to support risk management and analyses methodologies. Some probabilistic models exist, but …

Influence Of Ph On The Transport Of Silver Nanoparticles In Saturated Porous Media: Laboratory Experiments And Modeling, Jason R. Flory

Theses and Dissertations

Given the ubiquity of silver nanoparticles (AgNPs), the largest and fastest growing category of nanomaterials, and their potential for toxic effects to both humans and the environment, it is important to understand their environmental fate and transport. The purpose of this study is to gain information on the transport properties of unmodified AgNP suspensions in a glass bead-packed column under saturated flow conditions at different solution pH levels. Commercial AgNPs were characterized using high resolution transmission spectroscopy (HRTEM), dynamic light scattering (DLS) and ultraviolet (UV) visible spectroscopy. Transport data were collected at different pH levels (4, 6.5 and 9) at …

Evaluation Of Xmx/2l-Mil Virtual Impactor Performance And Capture And Retention Of Aerosol Particles In Two Different Collection Media, Jon E. Black

Theses and Dissertations

The United States Air Force uses the XMX/2L-MIL (XMX) high volume air sampler to collect samples for biological analysis. The XMX uses a virtual impactor to concentrate particles 1.0 to 10 μm in size into a secondary flow prior to sample collection using a liquid impinger in a collection tube. There are no known published studies regarding virtual impactor inter-instrument variability, effect of reducing the secondary flow on particle concentration, or capture and retention efficiency (CRE) of particles in the collection media performance characteristics when using the XMX. These performance characteristics were evaluated by lofting test aerosols of Arizona Road …

Development Of Optimized Guidelines For Therapeutic Strategies For Organophosphate Poisoning, Craig A. Holder

Theses and Dissertations

Organophosphates such as nerve agents have been used on several occasions in the past to inflict harm upon military and civilian populations in various parts of the world. The threat of these chemicals use against the military and civilians continues today, and the suggested treatment guidelines available may be ineffective or possibly cause harm. The guidelines investigated during the research presented here all included the use of two antidotes, atropine and oxime. The efficacy of oximes has been questioned and it has been suggested that they may cause harm to the patient. Both atropine and oxime are issued to military …

Retrospective Geospatial Modeling Of Pm10 Exposures From Open Burning At Joint Base Balad, Iraq, John P. Rinker

Theses and Dissertations

Predicting, determining, and linking theater-related source-specific exposures to health effects has proven difficult. The purpose of this research is to delineate retrospective exposure zones using spatially interpolated particulate air sampling point data from Joint Base Balad, create burn pit exposure isopleths from dispersion model outputs, and merge into a combined exposure model in GIS. Interpolated monitoring results and dispersion modeled results were combined to compare modeled exposures across base. Burn pit contribution to total PM10 was also modeled. The combined dispersion and interpolation map showed elevated concentrations within a 1 kilometer buffer of the burn pit. Buildings within this area …

Characterization Of Graphite Composite Material Particulates From Usaf Aircraft Maintenance Operations, Richard E. Yon

Theses and Dissertations

Due to the benefits of their material properties, advanced composite materials (ACM) are increasingly being used as structural components on aircraft, especially within the United States Air Force. As a result, the potential exists for occupational exposures to structural maintenance employees while repairing and fabricating aircraft components. Two field studies were conducted for this thesis in order to characterize ACM aerosol size distribution, determine the feasibility of utilizing direct reading instruments (DRIs) in the field, and ensure workers are protected with adequate controls. In order to characterize exposure, traditional integrated air sampling and DRIs were positioned together near an ACM …

Particulate Characterization And Control Evaluation For Carbon Fiber Composite Aircraft Crash Recovery Operations, Matthew R. Ferreri

Theses and Dissertations

Within the United States Air Force (USAF) Advanced Composite Material (ACM) is gaining an increasing use in military aircraft. With the number of aircraft that have increasingly large amounts of ACM materials, the probability of an incident with one of these aircraft also increases. When such an incident occurs the aircraft needs to be disassembled, removed, and later inspected as part of the accident investigation process. This disassembly process is termed “Crash Recovery Operations.” Carbon fibers have been shown to be hazardous to human health and a pilot study raised the suspicion that nanosized aerosol may be generated during the …

High Volume Air Sampling For Viral Aerosols: A Comparative Approach, Casey W. Cooper

Theses and Dissertations

The United States Air Force has high volume biological air sampling equipment available including the XMX/2L-MIL and DFU-1000. Neither system has been evaluated for effectiveness in the collection of viruses. Furthermore, decontamination methods have not been evaluated for these systems after use in sampling for a viral agent. MS2 bacteriophage was used as a surrogate virus. Aerosolized MS2 was released into a 12 m3 exposure chamber. High and moderate airborne concentrations of MS2 were evaluated. Low volume impingers were used for comparative purposes as well. Samples were analyzed using plaque assay and polymerase chain reaction (PCR). At high viral loads …

Development Of A Novel Noise Delivery System For Jp-8 Ototoxicity Studies, John E. Stubbs

Theses and Dissertations

Numerous chemicals with ototoxic properties may cause hearing loss directly, potentiate noise-induced hearing loss, or produce additive effects. Of interest to the US Air Force are studies showing ototoxic effects of JP-8 jet fuel and its hydrocarbon constituents. The Naval Health Research Center (NHRC) at Wright-Patterson AFB, Ohio, in conjunction with the USAF, is studying the ototoxic effects of JP-8 in rats. The study requires a white noise source that is one octave band wide, centered at 8 kHz frequency, delivered from outside of exposure chambers. Sound pressure levels must be within ± 2 dB at all exposure points within …

Shelter-In-Place: Indoor Exposure Assessment During An Airborne Chemical, Biological, Radiological, And Nuclear (Cbrn) Event, Robert D. Schmidtgoessling

Theses and Dissertations

The goal of Shelter-In-Place (SIP) is to reduce human exposure to chemical, biological, radiological, and nuclear (CBRN) agents in the event of an accidental or intentional airborne release into the outdoor environment. The Air Force Bioenvironmental Engineering (BE) career field is responsible for providing hazard identification, evaluation, and control capabilities as well as executing health risk assessments to recommend appropriate courses of action to commanders pre-, trans-, and post-incident. Specifically, BE is responsible for providing sampling, identification, and quantification input to hazard prediction models and supporting evacuation plan development to provide risk-based control recommendations. This also includes providing exposure and …

Field Evaluation Of A Novel Exposure Assessment Strategy Using Respirable Coal Dust Exposures During Heat Plant Coal Receiving Operations, Timothy W. Batten

Theses and Dissertations

An exposure assessment strategy (EAS) determines the number of samples required to characterize an occupational health exposure’s acceptability. A novel EAS (AFIT-EAS) was developed with the objective of maximizing the sensitivity for detecting unacceptable exposures, while minimizing the total number of samples needed. The purpose of this field evaluation was to use data from a comprehensive sampling campaign (SC) to compare the AFIT-EAS with two commonly used EASs: the Occupational Safety and Health Administration’s (OSHA-EAS) and the American Industrial Hygiene Association’s (AIHA-EAS). 10 randomly sampled replicates were selected from the SC. The number of samples selected per replicate was in …