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MCV/Q, Medical College of Virginia Quarterly

Clinical Applications

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Full-Text Articles in Medicine and Health Sciences

Introduction, Donald P. Becker Jan 1974

Introduction, Donald P. Becker

MCV/Q, Medical College of Virginia Quarterly

This issue represents the second part of the 27th Annual Stoneburner Lecture Series delivered at the Medical College of Virginia in February 1974. Here, we are dealing with clinical applications of recent advances in our understanding of brain mechanisms and brain disease processes.


Clinical Advances In The Management Of Patients With Sever Head Injury, Thomas W. Langfitt Jan 1974

Clinical Advances In The Management Of Patients With Sever Head Injury, Thomas W. Langfitt

MCV/Q, Medical College of Virginia Quarterly

Some of the physiological properties of the cerebral circulation, intracranial pressure and brain metabolism, as well as some of the pathophysiological alterations that we see with various types of brain injuries have been discussed in this series. We are going to see how we can apply some of this information clinically.


Continuous Intracranial Pressure Monitoring In Patients With Brain Injury: Technique And Application, John K. Vries Jan 1974

Continuous Intracranial Pressure Monitoring In Patients With Brain Injury: Technique And Application, John K. Vries

MCV/Q, Medical College of Virginia Quarterly

Continuous ICP monitoring using the hollow screw technique has proven itself simple, safe, and reliable. The obvious advantage of continuous ICP monitoring is to provide early warning of developing mass lesions before clinical signs appear and to assess the effectiveness of therapy directed at brain edema. Its most important use, however, may be that it permits the use of depressant medications in these patients. Many of these patients have a marked tendency toward hyperthermia, severe hyperventilation, and erratic blood pressure swings. These tendencies can be most difficult to control with conventional treatment regimens. By sedating these patients, however, it is …


Practical Anticonvulasant Pharmacokinetics, R.B. David, L.K. Garrettson Jan 1974

Practical Anticonvulasant Pharmacokinetics, R.B. David, L.K. Garrettson

MCV/Q, Medical College of Virginia Quarterly

Pharmacokinetics is that area of pharmacology concerned with the absorption, distribution, metabolism, and elimination of drugs. The processes by which absorption, distribution, and elimination take place are referred to as unit processes. These occur independently and concurrently, and involve such activities as absorption into the blood, elimination from the blood, distribution between the blood and tissue, inactivation in tissues, and finally, elimination from the blood. Drug handling by the body can be characterized by the rate for each step or, more often, the rate of all processes. Classification of observed kinetics for these rate processes includes first-order, zero-order, and capacity-limited …


Radical Reconstruction Of Complex Cranio-Orbito-Facial Abnormalities, John A. Jane, Milton T. Edgerton Jan 1974

Radical Reconstruction Of Complex Cranio-Orbito-Facial Abnormalities, John A. Jane, Milton T. Edgerton

MCV/Q, Medical College of Virginia Quarterly

Excellent cosmetic results can be obtained by early intervention in severe cranial-orbital-facial deformity. This intervention should take the form of a combined intracranial and extracranial approach. While the procedure is of great magnitude, the benefits to the patient and to the family seem worth the risk.


Author Index, Volume Ten, 1974. Jan 1974

Author Index, Volume Ten, 1974.

MCV/Q, Medical College of Virginia Quarterly

Author index for MCV/Q, Medical College of Virginia Quarterly, 1974, Volume Ten.


Advances In The Management Of Pituitary Tumors, Charles B. Wilson Jan 1974

Advances In The Management Of Pituitary Tumors, Charles B. Wilson

MCV/Q, Medical College of Virginia Quarterly

A new development in the management of pituitary tumors is the transsphenoidal technique. It will be my purpose to show that it provides an elegant way of handling the great majority of pituitary problems, at least the ones that I have encountered, although it has its shortcomings as well as its advantages.


Advances In The Medical And Surgical Management Of Intractable Partial Complex Seizures, Hooshang Hooshmand Jan 1974

Advances In The Medical And Surgical Management Of Intractable Partial Complex Seizures, Hooshang Hooshmand

MCV/Q, Medical College of Virginia Quarterly

Seizures can be due to a variety of acute, subacute, or chronic diseases with different etiologies. Clinically, they may manifest as focal or generalized phenomena. Whereas the majority of the patients suffering from partial seizures are easily controlled with medications, in a small number of patients treatment may fail. The failure may be due to incorrect diagnosis or incorrect therapy. The efficacy of medical treatment for seizure disorder depends upon six factors: 1) dosage; 2) the size of the patient; 3) drug interaction; 4) drug specificity for the disease; 5) the nature of the disease for which the drug is …


Advances In The Treatment Of Patients With Benign Brain Tumors, Harold F. Young Jan 1974

Advances In The Treatment Of Patients With Benign Brain Tumors, Harold F. Young

MCV/Q, Medical College of Virginia Quarterly

Reliable ICP measurement allows an exact quantitation and management of intracranial pressure. This precise assessment of ICP is a valuable adjunct in the management of anesthesia for brain tumor patients. The proper combination of ICP and anesthesia management enables the surgeon to use the operating microscope to approach previously inaccessible areas of the brain and to perform meticulous surgery with a better prognosis for the brain tumor patient.


Progress And Problems In The Rehabilitation Of Patients With Central Nervous System Injuries, L.D. Amick Jan 1974

Progress And Problems In The Rehabilitation Of Patients With Central Nervous System Injuries, L.D. Amick

MCV/Q, Medical College of Virginia Quarterly

Let us briefly consider the general nature of contemporary rehabilitation with highlights of its progress and problems. Paraplegia and hemiparesis may be thought of as the models of neurologic impairment.


Table Of Contents, Volume Ten, 1974. Jan 1974

Table Of Contents, Volume Ten, 1974.

MCV/Q, Medical College of Virginia Quarterly

Table of contents for MCV/Q, Medical College of Virginia Quarterly, 1974, Volume Ten.


Neuro-Ophthalmology In Severe Head Injury, John W. Harbison Jan 1974

Neuro-Ophthalmology In Severe Head Injury, John W. Harbison

MCV/Q, Medical College of Virginia Quarterly

If asked what the significance of neuro-ophthalmology is in the evaluation of severe head injury, many medical and surgical practitioners of neurology would promptly reply that it consists of monitoring pupillary reactivity in anticipation of the uncal herniation syndrome. A discussion of two broad premises of a factual nature, however, should easily convince these same practitioners that the neuro-ophthalmic evaluation of patients with severe head injuries offers far more than the Hutchinson pupil.


Advances In Neuroradiology, Frederick S. Vines, Charles Bonstelle Jan 1974

Advances In Neuroradiology, Frederick S. Vines, Charles Bonstelle

MCV/Q, Medical College of Virginia Quarterly

The development of two new radiological techniques has significantly enhanced the performance of neuroradiological diagnostic procedures. The first of these was installed as the prototype unit at the Medical College of Virginia in November of 1972 and has marked advantages for the performance of encephalography, angiography, and air myelography. The present communication will relate the experiences of the author during the initial 15 months of clinical evaluation. The second technique is an entirely new concept of obtaining further information from the data provided by the penetration of x-ray photons. Each of these units will be discussed briefly with an outline …


Advances In The Management Fo Patients With Malignant Brain Tumors, Charles B. Wilson Jan 1974

Advances In The Management Fo Patients With Malignant Brain Tumors, Charles B. Wilson

MCV/Q, Medical College of Virginia Quarterly

In describing what is new in the management of malignant brain tumors, I shall confine myself largely to chemotherapy and shall outline what we think is important based on our own experience, what we have achieved with single and multiple agents, and where we are going. We have just reviewed our five-year experience and find that chemotherapy, perhaps, is the only thing that is new.