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Full-Text Articles in Medicine and Health Sciences
Unique Characteristics And Implications Of Individual Health Profiles, George Z. Williams
Unique Characteristics And Implications Of Individual Health Profiles, George Z. Williams
MCV/Q, Medical College of Virginia Quarterly
During the era of the prescientific medicine, people were divided into two categories: those who were sick and those who were not sick. Physicians found it necessary to establish criteria to differentiate the ill and separate them according to symptoms and signs characteristic of classifiable diseases. Because of preoccupation with disease, the concept of the "normal" versus the pathological, as two opposite and definable conditions, was inevitable in the absence of scientific knowledge of human chemistry and physiology. This concept has carried over into the present era of scientific medicine.
Haa (Hb Ag) Evaluation-State Of The Art, Ali A. Hossaini, Mario R. Escobar
Haa (Hb Ag) Evaluation-State Of The Art, Ali A. Hossaini, Mario R. Escobar
MCV/Q, Medical College of Virginia Quarterly
In conclusion, this study supports the claim that the RIA is the most sensitive of all assay methods for detection of HB Ag in use today. Because of the inability to verify the presence of HB Ag in those sera positive by RIA alone, however, this claim must be taken only at face value. Further studies are needed to confirm the specificity of these positive reactions.
Abstracts Of Theses For Graduate Degrees
Abstracts Of Theses For Graduate Degrees
MCV/Q, Medical College of Virginia Quarterly
Medical College of Virginia, June, 1969. Summary includes: Anticholinergic Agents Based on Ariens' Dual Receptor Site Theory by Archie Jay Beebe; The Relationship Between Emotionality and Behavioral Performance in a Random Population of Male Charles River Rats by Stanley F. Bernstein; Fetal Development and Functional Significance of the Epiphysis Cerebri in Rats and Hamsters: A Light and Electron Microscopic Investigation by Jeanne W. Clabough; Separation and Partial Characterization of Components Derived from Human Erythrocyte Membranes by Roy Frederick J. Davis; Free Amino Acid Release from Isolated Rat Liver Cells by Gerald Irwin Drury; Passer Domesticus by William W. Farrar; The …
Transfusion Problems In Hemolytic Anemias, Ali A. Hossaini
Transfusion Problems In Hemolytic Anemias, Ali A. Hossaini
MCV/Q, Medical College of Virginia Quarterly
In this presentation I have attempted to present some of the transfusion problems that face the Blood Bank and the physician treating the patient. I have briefly discussed methods of recognizing the complicating factors, interpretation of their clinical significance, and the proper hemotherapeutic management of such cases. Finally, I hope that this presentation is a convincing thesis for a better understanding of the Blood Bank and its problems, since the patient's welfare is better served when there is a rapport between the clinician and the Blood Bank staff.
Determination Of Leukoagglutinin Specificity By In Vivo And In Vitro Studies, Ali A. Hossaini, Henry E. Wilson
Determination Of Leukoagglutinin Specificity By In Vivo And In Vitro Studies, Ali A. Hossaini, Henry E. Wilson
MCV/Q, Medical College of Virginia Quarterly
Results of testing sera from normal individuals and pathological patients, using a bromelin technique for the detection of leukoagglutinins, are reported. These results, supported further by an in vivo experiment, suggested that the phenomenon of leukoagglutination is immunologic in nature and that leukoagglutinins may be the cause of some febrile transfusion reactions. These are specifically directed against leukocytes, and do not involve the red cell series. Furthermore, the antigen (or antigens) is probably present in both the granulocytes and the mononuclear leukocytes. Anti-platelet antibodies could be presumed to be the cause of thrombocytopenia.
Clinical Hemodynamics And Pharmacodynamics Of Toxemia, Frank A. Finnerty Jr.
Clinical Hemodynamics And Pharmacodynamics Of Toxemia, Frank A. Finnerty Jr.
MCV/Q, Medical College of Virginia Quarterly
For many years toxemia has served as a wastebasket for a variety of disease states characterized by an elevated arterial pressure, edema, and albuminuria. Whereas this triad is consistent with the diagnosis of toxemia, it is not diagnostic. Besides toxemia, these abnormalities may be found in pregnant patients with hypertensive vascular disease, pyelonephritis, glomerulonephritis, or any combination of these. Data derived from studies performed on patients with such a variety of disease entities have obviously been confusing. It makes a lot of difference, for example, whether the subjects studied had chronic pyelonephritis or acute vasospastic toxemia. During the past 13 …
Γ-Guanidinobutyric Acid: An Inhibitor Of Clot Formation And Of Clot Lysis, Phyllis S. Roberts
Γ-Guanidinobutyric Acid: An Inhibitor Of Clot Formation And Of Clot Lysis, Phyllis S. Roberts
MCV/Q, Medical College of Virginia Quarterly
During a study of the effects of a series of guanidine compounds on the esterolytic activities of thrombin, plasmin, and streptokinase plus plasmin or plasminogen, it was found that one of these compunds, γ-guanidinobutyric acid (GGBA), acted in several ways like ε-aminocaproic acid (EACA). Neither compound had any inhibiting effects on the rate of hydrolysis of TAMe (p-toluenesulfonyl-L-arginine methyl ester), but both inhibited the activation of plasminogen by streptokinase. EACA was the more potent inhibitor. Since EACA has been shown to inhibit the lysis of fibrin, primarily because it inhibits the activation of plasminogen (Ablondi et al., 1959, Alkjaersig, Fletcher, …
The Effect Of Γ-Guanidinobutyric Acid On The Clotting Time Of Normal Plasma And On The Euglobulin Lysis Time Of Fibrinolytically Active Plasma, Lyman M. Fisher, Phyllis S. Roberts, Warner E. Braxton
The Effect Of Γ-Guanidinobutyric Acid On The Clotting Time Of Normal Plasma And On The Euglobulin Lysis Time Of Fibrinolytically Active Plasma, Lyman M. Fisher, Phyllis S. Roberts, Warner E. Braxton
MCV/Q, Medical College of Virginia Quarterly
It has been established that ε-aminocaproic acid (EACA) inhibits the activation of human plasminogen (Ablondi et al., 1959; Alkjaersig, Fletcher, and Sherry, 1959). Because of this observation, this compound has been used extensively to inhibit the pathologically occurring fibrinolytic system in patients. Recently Roberts (1965) reported that another compound, γ-guanidinobutyric acid (GGBA), like EACA, inhibits the lysis of human blood clots. Furthermore, GGBA, unlike EACA, retards the formation of these clots. The present investigation was undertaken to determine whether GGBA inhibits clot formation in the one-stage prothrombin and in the partial thromboplastin time tests. In addition, the ability of GGBA …
Γ-Globulin Administration And Anti-Globulin Antibodies In Children, Marion Waller, Nellie Curry
Γ-Globulin Administration And Anti-Globulin Antibodies In Children, Marion Waller, Nellie Curry
MCV/Q, Medical College of Virginia Quarterly
We examined sera from 185 non-hospitalized children, 44 of whom had received repeated injections of γ-globulin for upper respiratory infections. There was no significant difference in the incidence of anti-globulin antibodies in the two groups. The presence of anti-globulin antibodies could not be correlated with the level of γ-globulin in the children's sera or with the age of the children.