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Articles 1 - 30 of 47
Full-Text Articles in Medicine and Health Sciences
Mcv/Q, Medical College Of Virginia Quarterly, Vol. 3 No. 1
Mcv/Q, Medical College Of Virginia Quarterly, Vol. 3 No. 1
MCV/Q, Medical College of Virginia Quarterly
No abstract provided.
Sporotrichosis: The Significance Of Variations In Morphology Of Spores In The Tissues, Harry I. Lurie
Sporotrichosis: The Significance Of Variations In Morphology Of Spores In The Tissues, Harry I. Lurie
MCV/Q, Medical College of Virginia Quarterly
The histopathological diagnosis of sporotrichosis is briefly reviewed. The primary lesion consists basically of pseudo-epitheliomatous hyperplasia of the epidermis, intra-epidermal micro-abscesses, a non-specific dermal infiltrate and granulomata composed of central micro-abscess surrounded by a zone of histiocytes and multinucleated giant cells. The significance of the asteroid body is discussed. Evidence is presented to support the view that the development of asteroid bodies and the amount of eosinophilic material in these bodies is related to host resistance and that cigar bodies are found in those cases with little or no resistance and in whom the disease disseminates rapidly and wildly. Avenues …
Traumatic Hyphema: A Review Of Experience At The Medical College Of Virginia During The Past Decade, Walter J. Geeraets, Ching-Hung Liu, Dupont Guerry Iii
Traumatic Hyphema: A Review Of Experience At The Medical College Of Virginia During The Past Decade, Walter J. Geeraets, Ching-Hung Liu, Dupont Guerry Iii
MCV/Q, Medical College of Virginia Quarterly
Hyphema (hemorrhage into the anterior chamber of the eye), as the result of blunt injury to the eye, carries a potential danger of visual loss if not properly treated. This review of cases seen in the MCV Hospitals over the last decade lists some of the complications and stresses some of the important factors in the management.
Ovarian Cancer: Diagnosis And Treatment, Hans L. Kottmeier
Ovarian Cancer: Diagnosis And Treatment, Hans L. Kottmeier
MCV/Q, Medical College of Virginia Quarterly
I have made it my task with this paper to outline principles for the treatment of ovarian carcinoma. Emphasis has been laid on pathology and on anatomical extent of the growth. The extension of the tumor should be outlined in detail at clinical examination and at laparotomy. Excision of the carcinoma should be performed to the greatest possible extent. Every effort should be made to keep the capsule intact. In cases of serous and endometrioid carcinoma fixed to surrounding tissue by firm adhesions, it may be appropriate to restrict the operation to an explorative laparatomy and to operate on the …
Complications Of X-Irradiation Therapy Of Pelvic Malignancy, Michael R. Deddish
Complications Of X-Irradiation Therapy Of Pelvic Malignancy, Michael R. Deddish
MCV/Q, Medical College of Virginia Quarterly
In conclusion, a variety of sequelae that may follow x-radiation therapy of the lower abdomen and pelvis have been described. With the increasing use of supervoltage therapy and treatment with higher dosages, we can expect to see an increase in the number of injuries to internal organs. Surgical intervention after vigorous radiotherapy will be accompanied by more, and serious, complications. Careful planning of radiotherapy and regular observation during treatment by both the therapist and surgeon will do much to keep the clinician alert to the symptoms of overdosage.
Total Treatment Of Endometriosis, Clayton T. Beecham
Total Treatment Of Endometriosis, Clayton T. Beecham
MCV/Q, Medical College of Virginia Quarterly
Any discussion of endometriosis would be incomplete without an acknowledgment of the exceptional contributions Joe Vincent Meigs made to our understanding of this clinical entity. From the time of our founding member’s first published paper (Meigs, 1922) until his death, he was a contributor to our understanding of this disease. It was Meigs, who in his first publication pointed out the “atrophy” of endometriosis that occurred during pregnancy and lactation. In spite of this exceedingly important observation, 44 years ago, endometriosis was often treated like a malignant lesion. However, clinical understanding has led to the increasing use of conservative measures. …
Contributors
MCV/Q, Medical College of Virginia Quarterly
List of contributors to this issue includes Tassilo Antoine, Clayton T. Beecham, Werner Bickenbach, Michael R. Deddish, Walter J. Geeraets, DuPont Guerry, III, Otto Käser, Hans L. Kottmeier, Ching-hung Liu, Nicholas C. Louros, Harry I. Lurie, Victor F. Marshall, John A. Stallworthy, Howard C. Taylor, Jr., and Marion Waller.
Epidemiology Of Adverse Drug Reactions, Leighton E. Cluff
Epidemiology Of Adverse Drug Reactions, Leighton E. Cluff
MCV/Q, Medical College of Virginia Quarterly
I would like to conclude by citing two rather interesting observations we have made. Three-quarters of all the patients in all our surveillance who have allergic reactions to drugs have had peptic ulcer, ulcerative colitis, or neoplastic disease of the gastrointestinal tract. Of these patients, three-quarters of the drugs producing allergic reactions are administered orally. The rates of allergic reactions to individual drugs in patients with gastrointestinal disease as opposed to those without gastrointestinal disease receiving the same medication, are significantly increased. What the impact is of inflammatory gastrointestinal disease 1) upon the absorption of the drug, 2) upon its …
Some Perspectives On Immunosuppressive Drugs, Robert S. Schwartz
Some Perspectives On Immunosuppressive Drugs, Robert S. Schwartz
MCV/Q, Medical College of Virginia Quarterly
In conclusion, the antimetabolites have proven extremely interesting in the laboratory for the exploration of the mechanism of antibody synthesis and related problems. They have also proven to be extremely useful and interesting materials in the clinic. Whether they are going to replace any other standard forms of therapy, such as the corticosteroids, is, in my view, doubtful. Their use at the moment is experimental and their ultimate place in clinical medicine is by no means settled. They appear to have two important effects in man: 1) Suppression of antibody formation which can be, in many individuals, selective; and 2) …
The Pharmacology Of Newer Diuretics, Albert J. Wasserman
The Pharmacology Of Newer Diuretics, Albert J. Wasserman
MCV/Q, Medical College of Virginia Quarterly
There are now a number of different classes of diuretics with different pharmacologic effects. Several considerations dictate the choice of diuretic: 1. The responsiveness of the patient is of prime importance. If the patient is not known to be resistant to diuretic therapy, thiazides should be tried first. 2. The danger of alterations of volume and of electrolytes in the specific patient must be considered. Patients receiving digitalis will be subjected to much greater danger by the induction of hypokalemia than patients not receiving cardiac glycosides. 3. The pharmacologic effects of the specific diuretics must be understood for now the …
Iatrogenic Disorders, Robert H. Moser
Iatrogenic Disorders, Robert H. Moser
MCV/Q, Medical College of Virginia Quarterly
The contemporary physician and his patient are riding the crest of the most dramatic expansion of medical capability in history. But the rapid proliferation of medical knowledge has not been entirely benign. Although our reverses have been minor in contrast to our advances, negative effects cannot be ignored. My discussion involves one aspect of this problem--the emergence of what I have called "Diseases of Medical Progress" (Moser, 1964).
The Controversy Over Generic Equivalency Of Drugs, Werner Lowenthal
The Controversy Over Generic Equivalency Of Drugs, Werner Lowenthal
MCV/Q, Medical College of Virginia Quarterly
The truth about generic equivalency has not yet been determined. The arguments in the generic equivalency controversy are confounded by names, proprietary (trademark, brand name) as opposed to non-proprietary (generic, branded-generic), yet quality of the products is not necessarily related to any name. The efficacy and not the name of the product is important. The crucial question to ask is whether the product is clinically or therapeutically effective, giving reliable and uniform results.
Perspectives And Prospects In The Chemotherapy Of Gastrointestinal Cancer, William Regelson
Perspectives And Prospects In The Chemotherapy Of Gastrointestinal Cancer, William Regelson
MCV/Q, Medical College of Virginia Quarterly
5-Flourouracil (5-FU) is the best agent for the treatment of all gastrointestinal cancers but should be used with restraint, since severe toxicity does not guarantee increased response or survival time. Experimental work suggests that glucose enhances cellular uptake of 5-FU. Alkylating agents are definitely useful and occasionally produce long-term responses. Mitomycin C shows activity but is not available. There are reports of responses to methotrexate, vinca alkaloids, and mithramycin, but their place in the management of gastrointestinal cancer is not established. The usefulness of alkylating agents or 5-FU as adjuvants to surgery is not clear, but evidence is accumulating which …
Book Review, F. J. Spencer
Book Review, F. J. Spencer
MCV/Q, Medical College of Virginia Quarterly
The Traveler's Health Guide, B. H. Kean and Harold A. Tucker. Springfield, Illinois, Charles C. Thomas, 1965. The increase in foreign travel has produced an admirable interest in international health. Drs. Kean and Tucker's preface states that "This book has been written for the international traveler, with best wishes for his continuing good health." It contains information useful to the physician not only as a traveler, but also as a practitioner who must answer the queries of his medically sophisticated patients.
[Contributors]
MCV/Q, Medical College of Virginia Quarterly
List of contributors to this issue includes Leighton Cluff, George T. Harrell, Werner Lowenthal, Nancy H. McGinnis, Maurice McGregor, Robert H. Moser, William Regelson, John J. Schwab, Robert S. Schwartz, and Albert J. Wasserman.
Mcv/Q, Medical College Of Virginia Quarterly, Vol. 3 No. 3
Mcv/Q, Medical College Of Virginia Quarterly, Vol. 3 No. 3
MCV/Q, Medical College of Virginia Quarterly
No abstract provided.
Diagnostic Ultrasonography, Joseph H. Holmes
Diagnostic Ultrasonography, Joseph H. Holmes
MCV/Q, Medical College of Virginia Quarterly
It was the development of radar and sonar during the last World War which made the ultrasonic techniques I am going to talk about possible. Following the War, Dr. K. T. Dussik had the idea that, if one directed ultrasonic waves into the body, one might obtain echoes reflected from tissue surfaces in the same way that the Navy received echo information reflected from the submarine's hull. When he did this, he did get reflected echoes from within the body, and this opened the door for other investigators to demonstrate how this echo information could be made useful in diagnostic …
Continuing Education For What?, George E. Miller
Continuing Education For What?, George E. Miller
MCV/Q, Medical College of Virginia Quarterly
Continuing education should mean continuing self-education, not continuing instruction. If this desirable goal is to be accomplished, there must be movement away from the content model, which encourages dependence upon teachers, to a process model, which demands a significant measure of self-reliance--a shift away from preoccupation with courses and methods, toward an augmented concern for educational diagnosis and individualized therapy. It does not mean an immediate abandonment of present program forms, but it is likely to be accompanied by a slow erosion of the faith which presently supports them.
[Contributors]
MCV/Q, Medical College of Virginia Quarterly
List of contributors to this issue includes Joseph H. Holmes, George E. Miller, Robert W. Miller, and Charles O. Watlington.
Mcv/Q, Medical College Of Virginia Quarterly, Vol. 3 No. 4
Mcv/Q, Medical College Of Virginia Quarterly, Vol. 3 No. 4
MCV/Q, Medical College of Virginia Quarterly
No abstract provided.
Intracellular Co₂ Tension: Practice And Theory, Eugene D. Robin
Intracellular Co₂ Tension: Practice And Theory, Eugene D. Robin
MCV/Q, Medical College of Virginia Quarterly
I have been asked to discuss methods of measuring intracellular Pco₂ and to discuss the physiology and biochemistry of intracellular CO₂ tensions. Actually, I am in a relatively fortunate position in that my difficulties in discussing the methodology of intracellular Pco₂ measurements are considerably less than those which face my two colleagues. The reason for this becomes apparent if one analyzes the following quantitative relationships. [Includes discussion.]
Contributors
MCV/Q, Medical College of Virginia Quarterly
List of contributors to this issue includes Norman W. Carter, Frans F. Jӧbsis, and Eugene D. Robin.
Volume Three Author Index
MCV/Q, Medical College of Virginia Quarterly
Author index for MCV/Q, Medical College of Virginia Quarterly, Volume Three.
Autologous Agglutinators To Erythrocytes Sensitized With The Ripley Anti-Rh Antibody Digested With 14 Different Proteolytic Enzymes, Marion Waller
Autologous Agglutinators To Erythrocytes Sensitized With The Ripley Anti-Rh Antibody Digested With 14 Different Proteolytic Enzymes, Marion Waller
MCV/Q, Medical College of Virginia Quarterly
Studies with 14 different enzyme digested globulin preparations of a single anti-Rh serum Ripley has revealed an astonishing array of autoagglutinators to his enzymatically degraded anti-Rh antibodies. These serum aggulutinators did not differ from isologous agglutinators found in most human sera. They were found to be IgG globulins and were not demonstrable in the macroglobulin fraction of non-rheumatoid sera. The IgM agglutinating activity in rheumatoid sera is indistinguishable from rheumatoid factor.
On The Concept Of Radicalism In Surgery For Cervical Cancer, Nicholas C. Louros
On The Concept Of Radicalism In Surgery For Cervical Cancer, Nicholas C. Louros
MCV/Q, Medical College of Virginia Quarterly
The idea of a radical operation for carcinoma of the cervix originated with Ries and Wertheim. The purpose of this operation, which was applied by Wertheim in 1901, is to remove not only the affected organ, but also the parametrial tissues. However, the limits of the dissection of the parametrium have never been defined with anatomical precision. As a result the extent of such a dissection is left entirely to the choice of the individual surgeon. The results of such procedures, therefore, become difficult to compare statistically. It is time, therefore, to define what is meant by the term "radical."
Contents
MCV/Q, Medical College of Virginia Quarterly
Table of contents for MCV/Q, Medical College of Virginia Quarterly, Summer 1967, Volume Three, Number Two.
Symposium On Pelvic Surgery: The 1966 Mcguire Lectures And Symposium, Randolph H. Hoge
Symposium On Pelvic Surgery: The 1966 Mcguire Lectures And Symposium, Randolph H. Hoge
MCV/Q, Medical College of Virginia Quarterly
The Society of Pelvic Surgeons was formed in 1952 for the purpose of holding meetings for the free and informal interchange of ideas pertaining to pelvic surgery and related topics, and to exert influence for the betterment of the teaching and practice of pelvic surgery. In 1959 and again in 1966, the Society gave the McGuire Lectures and Symposium, thus diverging from its usual program of round table discussion among its own members.
The Treatment Of Anxiety, John J. Schwab, Nancy H. Mcginnis
The Treatment Of Anxiety, John J. Schwab, Nancy H. Mcginnis
MCV/Q, Medical College of Virginia Quarterly
Rational therapy requires accurate diagnosis. When we apply this precept to anxiety a fundamental question arises. Is anxiety an illness in terms of the now berated medical model which holds that an illness has a cause, a natural history, and hopefully a cure? Or is anxiety a basic aspect of the human condition, an innate pattern of response which becomes pathological when stress, induced by physiologic and social forces, is magnified out of proportion to the original stimulus? If the latter is true, then stress and social interactions are the causative factors, the anxiety only a reaction. Logically then, the …
Contents
MCV/Q, Medical College of Virginia Quarterly
Table of contents for MCV/Q, Medical College of Virginia Quarterly, 1967, Volume Three, Number Three.
Volume Three Table Of Contents
Volume Three Table Of Contents
MCV/Q, Medical College of Virginia Quarterly
Table of contents for MCV/Q, Medical College of Virginia Quarterly, Volume Three.