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Journal Articles

2020

Zucker School of Medicine at Hofstra/Northwell

Articles 1 - 30 of 592

Full-Text Articles in Medicine and Health Sciences

Combination Of Dasatinib With Chemotherapy In Previously Untreated Core Binding Factor Acute Myeloid Leukemia: Calgb 10801, G. Marcucci, S. Geyer, K. Laumann, W. Zhao, D. Bucci, G. L. Uy, W. Blum, A. K. Eisfeld, J. E. Kolitz, R. A. Larson, +7 Additional Authors Jan 2020

Combination Of Dasatinib With Chemotherapy In Previously Untreated Core Binding Factor Acute Myeloid Leukemia: Calgb 10801, G. Marcucci, S. Geyer, K. Laumann, W. Zhao, D. Bucci, G. L. Uy, W. Blum, A. K. Eisfeld, J. E. Kolitz, R. A. Larson, +7 Additional Authors

Journal Articles

© 2020 by The American Society of Hematology. Acutemyeloid leukemia (AML)witheither t(8;21)(q22;q22)or inv(16)(p13q22)/t(16;16)(p13;q22) is referred to as core binding factor (CBF) AML. Although categorized as favorable risk, long-term survival for these patients is only ∼50% to 60%. Mutated (mut) or overexpressed KIT, a gene encoding a receptor tyrosine kinase, has been found almost exclusively in CBF AML and may increase the risk of disease relapse. We tested the safety and clinical activity of dasatinib, a multi-kinase inhibitor, in combination with chemotherapy. Sixty-one adult patients with AML and CBF fusion transcripts (RUNX1/RUNX1T1 or CBFB/MYH11) were enrolled on Cancer and Leukemia Group …

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Cll Intraclonal Fractions Exhibit Established And Recently Acquired Patterns Of Dna Methylation, B. A. Bartholdy, X. Wang, X. Yan, M. Pascual, M. Fan, J. Barrientos, S. L. Allen, K. R. Rai, N. Chiorazzi, S. Roa, +2 Additional Authors Jan 2020

Cll Intraclonal Fractions Exhibit Established And Recently Acquired Patterns Of Dna Methylation, B. A. Bartholdy, X. Wang, X. Yan, M. Pascual, M. Fan, J. Barrientos, S. L. Allen, K. R. Rai, N. Chiorazzi, S. Roa, +2 Additional Authors

Journal Articles

No abstract provided.

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Multiplex Accurate Sensitive Quantitation (Masq) With Application To Minimal Residual Disease In Acute Myeloid Leukemia, A. B. Moffitt, M. S. Spector, P. Andrews, J. Kendall, J. Alexander, A. Stepansky, J. Kolitz, N. Chiorazzi, S. L. Allen, Z. Wang, +4 Additional Authors Jan 2020

Multiplex Accurate Sensitive Quantitation (Masq) With Application To Minimal Residual Disease In Acute Myeloid Leukemia, A. B. Moffitt, M. S. Spector, P. Andrews, J. Kendall, J. Alexander, A. Stepansky, J. Kolitz, N. Chiorazzi, S. L. Allen, Z. Wang, +4 Additional Authors

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No abstract provided.

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Covid-19 Presenting As Stroke, A. Avula, K. Nalleballe, N. Narula, S. Sapozhnikov, V. Dandu, S. Toom, A. Glaser, D. Elsayegh Jan 2020

Covid-19 Presenting As Stroke, A. Avula, K. Nalleballe, N. Narula, S. Sapozhnikov, V. Dandu, S. Toom, A. Glaser, D. Elsayegh

Journal Articles

© 2020 Elsevier Inc. Objective: Acute stroke remains a medical emergency even during the COVID-19 pandemic. Most patients with COVID-19 infection present with constitutional and respiratory symptoms; while others present with atypical gastrointestinal, cardiovascular, or neurological manifestations. Here we present a series of four patients with COVID-19 that presented with acute stroke. Methods: We searched the hospital databases for patients that presented with acute stroke and concomitant features of suspected COVID-19 infection. All patients who had radiographic evidence of stroke and PCR-confirmed COVID-19 infection were included in the study. Patients admitted to the hospital with PCR- confirmed COVID-19 disease whose …

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Acute Kidney Injury In Patients Hospitalized With Covid-19, J. S. Hirsch, J. H. Ng, D. W. Ross, H. H. Shah, R. L. Barnett, A. D. Hazzan, S. Fishbane, K. D. Jhaveri, M. Abate, A. Bellucci, M. C. Bhaskaran, M. Gitman, C. Halinski, S. Hasan, S. Hong, Y. Khanin, A. Kuan, V. Madireddy, D. Malieckal, A. Muzib Jan 2020

Acute Kidney Injury In Patients Hospitalized With Covid-19, J. S. Hirsch, J. H. Ng, D. W. Ross, H. H. Shah, R. L. Barnett, A. D. Hazzan, S. Fishbane, K. D. Jhaveri, M. Abate, A. Bellucci, M. C. Bhaskaran, M. Gitman, C. Halinski, S. Hasan, S. Hong, Y. Khanin, A. Kuan, V. Madireddy, D. Malieckal, A. Muzib

Journal Articles

© 2020 International Society of Nephrology The rate of acute kidney injury (AKI) associated with patients hospitalized with Covid-19, and associated outcomes are not well understood. This study describes the presentation, risk factors and outcomes of AKI in patients hospitalized with Covid-19. We reviewed the health records for all patients hospitalized with Covid-19 between March 1, and April 5, 2020, at 13 academic and community hospitals in metropolitan New York. Patients younger than 18 years of age, with end stage kidney disease or with a kidney transplant were excluded. AKI was defined according to KDIGO criteria. Of 5,449 patients admitted …

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Arterial Thromboembolic Complications In Covid-19 In Low-Risk Patients Despite Prophylaxis, D. O. Griffin, A. Jensen, M. Khan, J. Chin, K. Chin, R. Parnell, C. Awwad, D. Patel Jan 2020

Arterial Thromboembolic Complications In Covid-19 In Low-Risk Patients Despite Prophylaxis, D. O. Griffin, A. Jensen, M. Khan, J. Chin, K. Chin, R. Parnell, C. Awwad, D. Patel

Journal Articles

No abstract provided.

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Mutations Associated With A 17-Gene Leukemia Stem Cell Score And The Score’S Prognostic Relevance In The Context Of The European Leukemianet Classification Of Acute Myeloid Leukemia, M. Bill, D. Nicolet, J. Kohlschmidt, C. J. Walker, K. Mrózek, A. K. Eisfeld, D. Papaioannou, X. Rong-Mullins, J. E. Kolitz, C. D. Bloomfield, +8 Additional Authors Jan 2020

Mutations Associated With A 17-Gene Leukemia Stem Cell Score And The Score’S Prognostic Relevance In The Context Of The European Leukemianet Classification Of Acute Myeloid Leukemia, M. Bill, D. Nicolet, J. Kohlschmidt, C. J. Walker, K. Mrózek, A. K. Eisfeld, D. Papaioannou, X. Rong-Mullins, J. E. Kolitz, C. D. Bloomfield, +8 Additional Authors

Journal Articles

© 2020 Ferrata Storti Foundation. Leukemia stem cells (LSC) are more resistant to standard chemotherapy and their persistence during remission can cause relapse, which is still one of the major clinical challenges in the treatment of acute myeloid leukemia (AML). A better understanding of the mutational patterns and the prognostic impact of molecular markers associated with stemness could lead to better clinical management and improve patients’ outcomes. We applied a previously described 17-gene expression score comprising genes differently expressed between LSC and leukemic bulk blasts, for 934 adult patients with de novo AML, and studied associations of the 17-gene LSC …

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A Faculty Development Graduate Medical Education Retreat To Teach And Address Social Determinants Of Health., J. Martinez, A. Fornari, V. Vanhuse, E. Fried, O. T. Uwemedimo, E. J. Kim, J. Conigliaro, A. C. Yacht Jan 2020

A Faculty Development Graduate Medical Education Retreat To Teach And Address Social Determinants Of Health., J. Martinez, A. Fornari, V. Vanhuse, E. Fried, O. T. Uwemedimo, E. J. Kim, J. Conigliaro, A. C. Yacht

Journal Articles

Background:Social determinants of health (SDH) account for a large percentage of health outcomes. Therefore, ensuring providers can address SDH is paramount yet curricula in this area is limited. Aim:The authors aimed to raise awareness, identify learning opportunities, foster positive attitudes, and equip educators to implement SDH curriculum. Setting and participants:This retreat occurred at a large academic institution and had over 130 participants who represented 56 distinct training programs and over 20 disciplines. Program description:The retreat was titled "Social Determinants of Health: Walking in Your Patients' Shoes." The retreat was holistic and used a multidimensional approach that included traditional learning, team-based …

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Pulmonary Artery Aneurysm: A Review, M. Gupta, A. Agrawal, A. Iakovou, S. Cohen, R. Shah, A. Talwar Jan 2020

Pulmonary Artery Aneurysm: A Review, M. Gupta, A. Agrawal, A. Iakovou, S. Cohen, R. Shah, A. Talwar

Journal Articles

No abstract provided.

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Covid-19 In Kidney Transplant Recipients, V. Nair, N. Jandovitz, J. S. Hirsch, G. Nair, M. Abate, M. Bhaskaran, E. Grodstein, I. Berlinrut, D. Hirschwerk, S. L. Cohen, K. W. Davidson, A. J. Dominello, G. A. Osorio, S. Richardson, L. W. Teperman, E. P. Molmenti Jan 2020

Covid-19 In Kidney Transplant Recipients, V. Nair, N. Jandovitz, J. S. Hirsch, G. Nair, M. Abate, M. Bhaskaran, E. Grodstein, I. Berlinrut, D. Hirschwerk, S. L. Cohen, K. W. Davidson, A. J. Dominello, G. A. Osorio, S. Richardson, L. W. Teperman, E. P. Molmenti

Journal Articles

No abstract provided.

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Cytokine Secretion In Breast Cancer Cells – Milliplex Assay Data, K. Chen, L. Satlof, G. Stoffels, U. Kothapalli, N. Ziluck, M. Lema, L. Poretsky, D. Avtanski Jan 2020

Cytokine Secretion In Breast Cancer Cells – Milliplex Assay Data, K. Chen, L. Satlof, G. Stoffels, U. Kothapalli, N. Ziluck, M. Lema, L. Poretsky, D. Avtanski

Journal Articles

© 2019 The Author(s) Metastatic breast cancer is the most advanced stage of breast cancer and the leading cause of breast cancer mortality. Although understanding of the cancer progression and metastasis process has improved, the bi-directional communication between the tumor cell and the tumor microenvironment is still not well understood. Breast cancer cells are highly secretory, and their secretory activity is modulated by a variety of inflammatory stimuli present in the tumor microenvironment. Here, we characterized the cytokine expression in human breast cancer cells (MDA-MB-231, MCF-7, T-47D, and BT-474) in vitro using 41 cytokine MILLIPLEX assay. Further, we compared cytokine …

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The Impact Of United States Medical Licensing Exam (Usmle) Step 1 Cutoff Scores On Recruitment Of Underrepresented Minorities In Medicine: A Retrospective Cross-Sectional Study., M. Williams, E. J. Kim, K. Pappas, O. Uwemedimo, L. Marrast, R. Pekmezaris, J. Martinez Jan 2020

The Impact Of United States Medical Licensing Exam (Usmle) Step 1 Cutoff Scores On Recruitment Of Underrepresented Minorities In Medicine: A Retrospective Cross-Sectional Study., M. Williams, E. J. Kim, K. Pappas, O. Uwemedimo, L. Marrast, R. Pekmezaris, J. Martinez

Journal Articles

Background and Aims:United States Medical Licensing Exam (USMLE) scores are the single, most objective criteria for admission into residency programs in the country. Underrepresented minorities in medicine (URiM) are found to have lower USMLE scores compared to their White counterparts. The objective of this study is to examine how USMLE step 1 cutoff scores may exclude self-reported URiM from the residency interview process across various specialties. Methods:This was a retrospective cross-sectional study of 10 541 applicants to different residency programs at Zucker School of Medicine at Hofstra/Northwell Health between May 2014 and May 2015. We identified Blacks and Hispanics as …

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The Role Of Chest Imaging In Patient Management During The Covid-19 Pandemic: A Multinational Consensus Statement From The Fleischner Society., G. D. Rubin, C. J. Ryerson, L. B. Haramati, N. Sverzellati, J. P. Kanne, S. Raoof, N. W. Schluger, A. Volpi, J. Yim, A. N. Leung, +10 Additional Authors Jan 2020

The Role Of Chest Imaging In Patient Management During The Covid-19 Pandemic: A Multinational Consensus Statement From The Fleischner Society., G. D. Rubin, C. J. Ryerson, L. B. Haramati, N. Sverzellati, J. P. Kanne, S. Raoof, N. W. Schluger, A. Volpi, J. Yim, A. N. Leung, +10 Additional Authors

Journal Articles

With more than 900,000 confirmed cases worldwide and nearly 50,000 deaths during the first three months of 2020, the COVID-19 pandemic has emerged as an unprecedented healthcare crisis. The spread of COVID-19 has been heterogeneous, resulting in some regions having sporadic transmission and relatively few hospitalized patients with COVID-19 and others having community transmission that has led to overwhelming numbers of severe cases. For these regions, healthcare delivery has been disrupted and compromised by critical resource constraints in diagnostic testing, hospital beds, ventilators, and healthcare workers who have fallen ill to the virus exacerbated by shortages of personal protective equipment. …

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Mir193a Modulation And Podocyte Phenotype, A. Jha, S. Saha, K. Ayasolla, H. Vashistha, A. Malhotra, K. Skorecki, P. C. Singhal Jan 2020

Mir193a Modulation And Podocyte Phenotype, A. Jha, S. Saha, K. Ayasolla, H. Vashistha, A. Malhotra, K. Skorecki, P. C. Singhal

Journal Articles

Apolipoprotein L1 (APOL1)-miR193a axis has been reported to play a role in the maintenance of podocyte homeostasis. In the present study, we analyzed transcription factors relevant to miR193a in human podocytes and their effects on podocytes' molecular phenotype. The motif scan of the miR193a gene provided information about transcription factors, including YY1, WT1, Sox2, and VDR-RXR heterodimer, which could potentially bind to the miR193a promoter region to regulate miR193a expression. All structure models of these transcription factors and the tertiary structures of the miR193a promoter region were generated and refined using computational tools. The DNA-protein complexes of the miR193a promoter …

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Management Of Upper Gi Bleeding In Patients With Covid-19 Pneumonia, K. Cavaliere, C. Levine, P. Wander, D. V. Sejpal, A. J. Trindade Jan 2020

Management Of Upper Gi Bleeding In Patients With Covid-19 Pneumonia, K. Cavaliere, C. Levine, P. Wander, D. V. Sejpal, A. J. Trindade

Journal Articles

No abstract provided.

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Famotidine Use Is Associated With Improved Clinical Outcomes In Hospitalized Covid-19 Patients: A Propensity Score Matched Retrospective Cohort Study., D. E. Freedberg, J. Conigliaro, T. C. Wang, K. J. Tracey, M. V. Callahan, J. A. Abrams, Famotidine Research Group Famotidine Research Grou, M. E. Sobieszczyk, D. D. Markowitz, A. Gupta, M. R. O'Donnell, J. Li, D. A. Tuveson, Z. Jin, W. C. Turner, D. W. Landry Jan 2020

Famotidine Use Is Associated With Improved Clinical Outcomes In Hospitalized Covid-19 Patients: A Propensity Score Matched Retrospective Cohort Study., D. E. Freedberg, J. Conigliaro, T. C. Wang, K. J. Tracey, M. V. Callahan, J. A. Abrams, Famotidine Research Group Famotidine Research Grou, M. E. Sobieszczyk, D. D. Markowitz, A. Gupta, M. R. O'Donnell, J. Li, D. A. Tuveson, Z. Jin, W. C. Turner, D. W. Landry

Journal Articles

No abstract provided.

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Pretreatment Nutritional Status And Response To Checkpoint Inhibitors In Lung Cancer., C. Lee, C. E. Devoe, X. Zhu, J. S. Fishbein, N. Seetharamu Jan 2020

Pretreatment Nutritional Status And Response To Checkpoint Inhibitors In Lung Cancer., C. Lee, C. E. Devoe, X. Zhu, J. S. Fishbein, N. Seetharamu

Journal Articles

Background:Checkpoint inhibitors are integral to non-small-cell lung cancer treatment. Existing data suggests that nutritional status may play a role in antitumor immunity. Materials & methods:This retrospective study of 106 non-small-cell lung cancer patients who started checkpoint inhibitors between 2014 and 2017 at our institution assessed relationship of nutritional parameters to overall survival (OS) and progression-free survival. Results:Mean age was 68.7 ± 9.2 years and 59.4% patients were male. On multivariate analysis for OS, hypoalbuminemia and significant weight loss were prognostic at p-values of 0.0005 and 0.0052, respectively. We noted a parabolic association between age and OS (p = 0.026, 0.0025). …

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The Uses Of Overnight Pulse Oximetry, S. Singh, S. Khan, D. Singh, S. Verma, A. Talwar Jan 2020

The Uses Of Overnight Pulse Oximetry, S. Singh, S. Khan, D. Singh, S. Verma, A. Talwar

Journal Articles

© 2020 Indian Chest Society Published by Wolters Kluwer - Medknow. Overnight pulse oximetry (OPO) has proven to be an effective and beneficial technique to determine the cardiorespiratory status of patients in both the inpatient and outpatient settings. It is a cheap, safe, reliable, simple, and accurate method of patient monitoring as compared to the expensive and labor-intensive method of multichannel polysomnography for detecting sleep-disordered breathing. It provides accurate information about patient's oxygenation status and also helps in monitoring the response to continuous positive airway pressure and in the surgical treatment of obstructive sleep apnea (OSA). Nocturnal hypoxemia portends a …

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Covid-19: Magnifying The Effect Of Health Disparities, E. J. Kim, L. Marrast, J. Conigliaro Jan 2020

Covid-19: Magnifying The Effect Of Health Disparities, E. J. Kim, L. Marrast, J. Conigliaro

Journal Articles

No abstract provided.

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Acthar Gel (Repository Corticotropin Injection) For Persistently Active Sle: Study Design And Baseline Characteristics From A Multicentre, Randomised, Double-Blind, Placebo-Controlled Trial, A. D. Askanase, E. Zhao, J. Zhu, E. Connolly-Strong, R. A. Furie Jan 2020

Acthar Gel (Repository Corticotropin Injection) For Persistently Active Sle: Study Design And Baseline Characteristics From A Multicentre, Randomised, Double-Blind, Placebo-Controlled Trial, A. D. Askanase, E. Zhao, J. Zhu, E. Connolly-Strong, R. A. Furie

Journal Articles

© 2020 Author(s). Objective SLE is a chronic inflammatory autoimmune disease characterised by the excessive production of autoantibodies, immune complexes and proinflammatory cytokines. Repository corticotropin injection (RCI) is a naturally sourced complex mixture of adrenocorticotropic hormone analogues and other pituitary peptides. RCI is approved by the US Food and Drug Administration for use during an exacerbation or as maintenance therapy in select cases of SLE. This paper discusses the design and baseline characteristics of a multicentre, double-blind, randomised, placebo-controlled, 24-week clinical trial evaluating the effect of RCI in reducing disease activity for patients with persistently active SLE despite moderate-dose corticosteroid …

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Knowledge, Attitudes, And Interactions With Chaplains And Nursing Northwell Health Outcomes: A Survey Study, T. Liberman, A. Kozikowski, M. Carney, M. Kline, A. Axelrud, A. Ofer, M. Rossetti, R. Pekmezaris Jan 2020

Knowledge, Attitudes, And Interactions With Chaplains And Nursing Northwell Health Outcomes: A Survey Study, T. Liberman, A. Kozikowski, M. Carney, M. Kline, A. Axelrud, A. Ofer, M. Rossetti, R. Pekmezaris

Journal Articles

© 2020, Springer Science+Business Media, LLC, part of Springer Nature. We conducted a cross-sectional survey of nursing Northwell Health (n = 51) in an academic hospital finding a significant inverse relationship between the frequency of chaplaincy interaction and perceived stress (r = − 0.27, p = 0.05). We also found a significant positive relationship between rated importance of having a chaplain at the hospital and secondary trauma (r = 0.30, p = 0.03). There was a significant positive relationship between religiosity and rated importance for having a chaplain (r = 0.30, p = 0.03) and rated helpfulness of chaplains (r …

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Chagas Disease In The New York City Metropolitan Area., C. Zheng, O. Quintero, E. K. Revere, M. B. Oey, F. Espinoza, Y. A. Puius, D. Ramirez-Baron, C. R. Salama, L. F. Hidalgo, H. B. Tanowitz, +5 Additional Authors Jan 2020

Chagas Disease In The New York City Metropolitan Area., C. Zheng, O. Quintero, E. K. Revere, M. B. Oey, F. Espinoza, Y. A. Puius, D. Ramirez-Baron, C. R. Salama, L. F. Hidalgo, H. B. Tanowitz, +5 Additional Authors

Journal Articles

Background:Chagas disease, caused by the parasite Trypanosoma cruzi, once considered a disease confined to Mexico, Central America, and South America, is now an emerging global public health problem. An estimated 300 000 immigrants in the United States are chronically infected with T. cruzi. However, awareness of Chagas disease among the medical community in the United States is poor. Methods:We review our experience managing 60 patients with Chagas disease in hospitals throughout the New York City metropolitan area and describe screening, clinical manifestations, EKG findings, imaging, and treatment. Results:The most common country of origin of our patients was El Salvador (n …

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Polycystic Liver With Cardiac Compression Leading To Atrial Fibrillation: Case Report And Review Of The Literature., A. Elfiky, C. T. El Imad, B. Karam, S. M. Mulrooney Jan 2020

Polycystic Liver With Cardiac Compression Leading To Atrial Fibrillation: Case Report And Review Of The Literature., A. Elfiky, C. T. El Imad, B. Karam, S. M. Mulrooney

Journal Articles

Polycystic liver disease (PCLD) is a rare condition that most often occurs in patients with polycystic kidney disease and less commonly as an isolated liver disease. Complications include cyst rupture, infection, hemorrhage, and compression of surrounding organs by large cysts. We present the case of a patient with a history of PCLD who presented to our hospital with palpitations and was found to have atrial fibrillation. Imaging and echocardiograph revealed a dominant large cyst compressing the right atrium. Other etiologies including thyroid disease, ischemic heart disease, and electrolytes abnormalities were excluded. The patient refused surgical intervention and was conservatively treated …

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Obstructive Lung Disease Secondary To Compression Of The Bronchus By An Enlarged Pulmonary Artery, J. Panthappattu, V. Sharma, S. Verma, A. Talwar Jan 2020

Obstructive Lung Disease Secondary To Compression Of The Bronchus By An Enlarged Pulmonary Artery, J. Panthappattu, V. Sharma, S. Verma, A. Talwar

Journal Articles

© 2020 Indian Chest Society Published by Wolters Kluwer - Medknow. In clinical practice, the presence of wheezing generally indicates an airway disease. In rare circumstances, adjacent mediastinal structures may compress the tracheobronchial tree leading to obstructive physiology. Compression of the tracheobronchial region by an enlarged pulmonary artery (PA) is exceedingly rare. We present here a case of pulmonary hypertension, where the enlarged PA resulted in obstructive lung physiology with a relevant review of the literature.

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Over-The-Scope Clip To The Rescue! A Novel Tool For Refractory Acute Nonvariceal Upper Gastrointestinal Hemorrhage, S. Amarnath, H. Khan, J. Philipose, J. Abergel Jan 2020

Over-The-Scope Clip To The Rescue! A Novel Tool For Refractory Acute Nonvariceal Upper Gastrointestinal Hemorrhage, S. Amarnath, H. Khan, J. Philipose, J. Abergel

Journal Articles

© 2020 © 2020 The Author(s). Published by S. Karger AG, Basel. Nonvariceal upper gastrointestinal hemorrhage (NVUGIH) is more prevalent than lower gastrointestinal hemorrhage and carries a high risk of mortality in the elderly, especially those with significant cardiovascular comorbidities. Traditional endoscopic methods, such as through-the-scope clips, electrocautery, and epinephrine injection, are frequently used to control these bleeds; however, they carry a 10% risk of rebleeding, and this itself carries a mortality risk of 36%. The larger over-the-scope clips (OTSC) that were initially used for the closure of fistulas and perforations are now gradually being implemented to manage NVUGIH. To …

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A Case Of Plasmodium Falciparum Malaria With A Prolonged Incubation Period Of Four Years., E. Sleiman, A. Upadhyaya, A. Glaser, M. Krzyzak Jan 2020

A Case Of Plasmodium Falciparum Malaria With A Prolonged Incubation Period Of Four Years., E. Sleiman, A. Upadhyaya, A. Glaser, M. Krzyzak

Journal Articles

With increased global travel, unique diseases from different parts of the world pose a new category of differential diagnosis, and an incubation period of different infectious diseases helps narrow differential diagnosis to point to one specific etiology. The normal incubation period of Plasmodium falciparum malariais 7-40 days. We report a case of symptomatic P. falciparum malaria that manifested four years after a visit to a malaria-endemic area in a 51-year-old female patient. Our case illustrates the importance of a broad differential with regard to infectious disease including remote travel history and raises questions of the survival of P. falciparum for …

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Eikenella Corrodens And Streptococcus Anginosus Co-Infection Causing Skull Base Osteomyelitis And Internal Carotid Artery Lesion, K. Patel, C. Park, Z. Memon, N. Ilyas Jan 2020

Eikenella Corrodens And Streptococcus Anginosus Co-Infection Causing Skull Base Osteomyelitis And Internal Carotid Artery Lesion, K. Patel, C. Park, Z. Memon, N. Ilyas

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© 2020 The Author(s) A 35-year-old male presented with headaches and fevers. MRI of his head showed skull-based infection of the clivus extended to the right internal carotid artery. Blood and sinus cultures were positive for Eikenella corrodens and Streptococcus anginosus. He had intravenous antibiotics and sinus washout. The patient had full neurological recovery following this.

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Pulmonary Artery Dilatation And Obstructive Sleep Apnea, J. Simonson, H. Greenberg, A. Talwar Jan 2020

Pulmonary Artery Dilatation And Obstructive Sleep Apnea, J. Simonson, H. Greenberg, A. Talwar

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No abstract provided.

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Inflammation And Erythropoiesis-Stimulating Agent Hyporesponsiveness: A Critical Connection, H. H. Shah, N. N. Uppal, S. Fishbane Jan 2020

Inflammation And Erythropoiesis-Stimulating Agent Hyporesponsiveness: A Critical Connection, H. H. Shah, N. N. Uppal, S. Fishbane

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No abstract provided.

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Covid-19 Presenting As Acute Hepatitis, P. Wander, M. Epstein, D. Bernstein Jan 2020

Covid-19 Presenting As Acute Hepatitis, P. Wander, M. Epstein, D. Bernstein

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No abstract provided.

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