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Medicine and Health Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Journal Articles

2014

Biochemistry & Molecular Biology;; Cell Biology;; Medicine

Articles 1 - 3 of 3

Full-Text Articles in Medicine and Health Sciences

A Systematic Nomenclature For The Redox States Of High Mobility Group Box (Hmgb) Proteins, D. J. Antoine, H. E. Harris, U. Andersson, K. J. Tracey, M. E. Bianchi Jan 2014

A Systematic Nomenclature For The Redox States Of High Mobility Group Box (Hmgb) Proteins, D. J. Antoine, H. E. Harris, U. Andersson, K. J. Tracey, M. E. Bianchi

Journal Articles

High mobility group box 1 (HMGB1) is a central mediator in inflammation and immunity. Recently, it was shown that different redox states of the three cysteines of HMGB1 endow it with mutually exclusive activities, such as inducing chemotaxis or the transcription of cytokines and chemokines, via the interaction with different receptors. The different HMGB1 redox forms can be identified by mass spectrometry in body fluids of patients and may hold promise as biomarkers. We propose here a systematic nomenclature of the different redox forms of HMGB1 and related proteins, to replace the conflicting names used so far by different laboratories.


Farewell Statement From Dr. Cerami And Dr. Tracey As Outgoing Co-Editors In Chief Of Molecular Medicine, A. Cerami, K. J. Tracey Jan 2014

Farewell Statement From Dr. Cerami And Dr. Tracey As Outgoing Co-Editors In Chief Of Molecular Medicine, A. Cerami, K. J. Tracey

Journal Articles

No abstract provided.


Letter From Incoming Editor In Chief Of Molecular Medicine, Dr. Betty Diamond, B. Diamond Jan 2014

Letter From Incoming Editor In Chief Of Molecular Medicine, Dr. Betty Diamond, B. Diamond

Journal Articles

No abstract provided.